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A. Lespagnol · SciRah

Researcher profile · Semantic Scholar

A. Lespagnol

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A. Lespagnol — researcher profile on SciRah

h-index: 20
Works: 44
Citations: 2,006

Most-cited papers

Exosome secretion, including the DNA damage-induced p53-dependent secretory pathway, is severely compromised in TSAP6/Steap3-null mice
A. Lespagnol, D. Duflaut, C. Beekman, L. Blanc +5 more
2008Cell Death and Differentiation344 citations
Semantic Scholar
Translationally controlled tumor protein is a target of tumor reversion.
M. Tuynder, G. Fiucci, S. Prieur, A. Lespagnol +9 more
2004Proceedings of the National Academy of Sciences of the United States of America244 citations Open access
Semantic Scholar
TCTP protects from apoptotic cell death by antagonizing bax function
Laurent Susini, S. Besse, D. Duflaut, A. Lespagnol +11 more
2008Cell Death and Differentiation215 citations
Semantic Scholar
Reciprocal repression between P53 and TCTP
R. Amson, S. Pece, A. Lespagnol, Rajesh Vyas +11 more
2011Nature Medicine214 citations
Semantic Scholar
Parallel FISH and Immunohistochemical Studies of ALK Status in 3244 Non–Small-Cell Lung Cancers Reveal Major Discordances
F. Cabillic, A. Gros, F. Dugay, H. Bégueret +13 more
2014Journal of Thoracic Oncology152 citations Open access
Semantic Scholar
The p53-inducible TSAP6 gene product regulates apoptosis and the cell cycle and interacts with Nix and the Myt1 kinase
Brent J. Passer, V. Nancy-Portebois, Nathalie Amzallag, S. Prieur +13 more
2003Proceedings of the National Academy of Sciences of the United States of America124 citations Open access
Semantic Scholar
A framework for validating AI in precision medicine: considerations from the European ITFoC consortium
R. Tsopra, X. Fernández, C. Luchinat, L. Alberghina +30 more
2021BMC Medical Informatics and Decision Making107 citations Open access
Semantic Scholar
Siah-1b is a direct transcriptional target of p53: identification of the functional p53 responsive element in the siah-1b promoter.
G. Fiucci, Séverine Beaucourt, D. Duflaut, A. Lespagnol +11 more
2004Proceedings of the National Academy of Sciences of the United States of America88 citations Open access
Semantic Scholar
Association of AXL and PD-L1 Expression with Clinical Outcomes in Patients with Advanced Renal Cell Carcinoma Treated with PD-1 Blockade
S. Terry, C. Dalban, N. Rioux-Leclercq, J. Adam +20 more
2021Clinical Cancer Research71 citations Open access
Semantic Scholar
Positive Association Between Location of Melanoma, Ultraviolet Signature, Tumor Mutational Burden, and Response to Anti–PD-1 Therapy
L. Dousset, F. Poizeau, C. Robert, S. Mansard +24 more
2021JCO Precision Oncology56 citations Open access
Semantic Scholar
Independent association of PD‐L1 expression with noninactivated VHL clear cell renal cell carcinoma—A finding with therapeutic potential
S. Kammerer-Jacquet, L. Crouzet, A. Brunot, J. Dagher +16 more
2017International Journal of Cancer49 citations
Semantic Scholar
Prognostic and predictive values of oncogenic BRAF, NRAS, c‐KIT and MITF in cutaneous and mucous melanoma
M. Pracht, Ariane Mogha, A. Lespagnol, A. Fautrel +10 more
2015Journal of the European Academy of Dermatology and Venereology39 citations
Semantic Scholar
Deep Learning for Detecting BRCA Mutations in High-Grade Ovarian Cancer based on an Innovative Tumor Segmentation Method from Whole-Slide Images.
R. Bourgade, Noémie Rabilloud, T. Perennec, T. Pécot +12 more
2023Modern Pathology29 citations Open access
Semantic Scholar
Synchronous Metastatic Clear‐Cell Renal Cell Carcinoma: A Distinct Morphologic, Immunohistochemical, and Molecular Phenotype
S. Kammerer-Jacquet, A. Brunot, A. Pladys, G. Bouzillé +13 more
2017Clinical Genitourinary Cancer29 citations Open access
Semantic Scholar
Correlation of c-MET Expression with PD-L1 Expression in Metastatic Clear Cell Renal Cell Carcinoma Treated by Sunitinib First-Line Therapy
S. Kammerer-Jacquet, Sarah Medane, K. Bensalah, J. Bernhard +13 more
2017Targeted oncology28 citations Open access
Semantic Scholar
Circulating tumor DNA is detectable in canine histiocytic sarcoma, oral malignant melanoma, and multicentric lymphoma
A. Prouteau, J. Denis, P. de Fornel, É. Cadieu +13 more
2021Scientific Reports27 citations Open access
Semantic Scholar
Wild-type VHL Clear Cell Renal Cell Carcinomas Are a Distinct Clinical and Histologic Entity: A 10-Year Follow-up.
J. Dagher, S. Kammerer-Jacquet, A. Brunot, A. Pladys +10 more
2016European Urology Focus27 citations Open access
Semantic Scholar
Genomic organization and expression of mouse Tpt1 gene.
G. Fiucci, A. Lespagnol, Pamela Stumptner-Cuvelette, Séverine Beaucourt +4 more
2003Genomics27 citations
Semantic Scholar
Depicting the genetic architecture of pediatric cancers through an integrative gene network approach
Clara Savary, Artem Kim, A. Lespagnol, V. Gandemer +6 more
2020Scientific Reports25 citations Open access
Semantic Scholar
EFGR-mutant lung adenocarcinoma and Li-Fraumeni syndrome: report of two cases and review of the literature.
C. Ricordel, M. Labalette-Tiercin, A. Lespagnol, M. Kerjouan +4 more
2015Lung Cancer20 citations Open access
Semantic Scholar
Clear cell renal cell carcinoma: a comparative study of histological and chromosomal characteristics between primary tumors and their corresponding metastases
J. Dagher, S. Kammerer-Jacquet, F. Dugay, Marion Beaumont +6 more
2017Virchows Archiv18 citations
Semantic Scholar
Standardisation of pathogenicity classification for somatic alterations in solid tumours and haematologic malignancies.
Florence Koeppel, Etienne Muller, Alexandre Harlé, C. Guien +16 more
2021European Journal of Cancer15 citations Open access
Semantic Scholar
Implementation of a molecular tumor board at a regional level to improve access to targeted therapy
H. Bourien, A. Lespagnol, B. Campillo-Gimenez, Ingrid Felten-Vinot +12 more
2020International Journal of Clinical Oncology14 citations Open access
Semantic Scholar
Mutational Landscape of DDR2 Gene in Lung Squamous Cell Carcinoma Using Next‐generation Sequencing
C. Ricordel, A. Lespagnol, F. Llamas-Gutiérrez, M. de Tayrac +7 more
2017Clinical Lung Cancer14 citations
Semantic Scholar
FACILITATE: A real-world, multicenter, prospective study investigating the utility of a rapid, fully automated real-time PCR assay versus local reference methods for detecting epidermal growth factor receptor variants in NSCLC
A. Behnke, A. Cayre, G. De Maglio, G. Giannini +14 more
2023Pathology and Oncology Research11 citations Open access
Semantic Scholar
[Predictive biomarkers of response to immune checkpoint inhibitors].
Alexandra Frelau, M. Pracht, S. Le Sourd, A. Lespagnol +5 more
2018Bulletin du Cancer6 citations Open access
Semantic Scholar
Multiple metastatic clones assessed by an integrative multiomics strategy in clear cell renal carcinoma: a case study
J. Dagher, A. Brunot, B. Evrard, S. Kammerer-Jacquet +10 more
2021Journal of Clinical Pathology5 citations Open access
Semantic Scholar
Metastatic Clear-cell Renal Cell Carcinoma With a Long-term Response to Sunitinib: A Distinct Phenotype Independently Associated With Low PD-L1 Expression.
S. Kammerer-Jacquet, A. Brunot, M. Lefort, S. Bayat +13 more
2019Clinical Genitourinary Cancer4 citations Open access
Semantic Scholar
MiR-31-3p do not predict anti-EGFR efficacy in first-line therapy of RAS wild-type metastatic right-sided colon cancer.
E. Boisteau, A. Lespagnol, M. de Tayrac, Sébastien Corre +25 more
2022Clinics And Research in Hepatology and Gastroenterology3 citations Open access
Semantic Scholar
Hilar fat infiltration: A new prognostic factor in metastatic clear cell renal cell carcinoma with first-line sunitinib treatment.
S. Kammerer-Jacquet, A. Brunot, K. Bensalah, B. Campillo-Gimenez +14 more
2017Urologic oncology2 citations Open access
Semantic Scholar
Evaluation of droplet digital PCR for the clinical diagnosis of toxoplasmosis
Elise Recalt, A. Lespagnol, Lya Hamet, H. Guegan +3 more
2025Microbiology spectrum1 citations Open access
Semantic Scholar
Interest of circulating tumor DNA as a biomarker for canine cancers: illustration in histiocytic sarcoma, oral malignant melanoma and multicentric lymphoma
A. Prouteau, J. Denis, P. de Fornel, É. Cadieu +13 more
2020bioRxiv1 citations Open access
Semantic Scholar
Tumour mutational burden and response to PD-1 inhibitors: An analysis of 89 cases of metastatic melanoma
L. Dousset, L. Boussemart, C. Robert, S. Mansard +16 more
2019Annals of Oncology1 citations Open access
Semantic Scholar
[GFCO national recommendations on the use of liquid biopsy for circulating tumor DNA analysis in oncology].
Alexandre Harlé, Léa Payen, A. Lespagnol, Nicolas Goardon +7 more
2026Bulletin du Cancer0 citations Open access
Semantic Scholar
Identification of a novel CTNNA1 germline mutation predisposing to melanoma: Genotype and functional effects.
A. Forestier, Laure Masson, Anne-Gaëlle Rio, A. Lespagnol +16 more
20210 citations
Semantic Scholar
Circulating tumor DNA is detectable in canine histiocytic sarcoma, oral malignant melanoma, and multicentric lymphoma
A. Prouteau, J. Denis, P. de Fornel, É. Cadieu +13 more
2021Scientific Reports0 citations Open access
Semantic Scholar
Nomogram Predicting Prognosis in Metastatic Patients with Clear Cell Renal Cell Carcinoma Treated by First-Line Sunitinib
S. Kammerer-Jacquet, F. Dugay, K. Bensalah, A. Brunot +15 more
20170 citations
Semantic Scholar
Hilar Fat Infiltration: An Independent Prognostic Factor in Metastatic Clear Cell Renal Cell Carcinoma with Sunitinib First-Line Treatment
S. Kammerer-Jacquet, A. Brunot, Karim Benasalah, B. Campillo-Gimenez +14 more
20170 citations
Semantic Scholar
External quality assessment of EGFR testing in circulating DNA: a french pilot study
M. Denis, I. Rouquette, A. Morel, C. Villalva +5 more
20160 citations Open access
Semantic Scholar
Targeted high-throughput sequencing for the routine diagnosis of somatic theranostic mutations on formalin-fixed, paraffin-embedded FFPE tumor samples: A prospective study of 3366 cancer samples.
J. Mosser, A. Lespagnol, Amyra Aliouat, A. Mosser +5 more
20150 citations
Semantic Scholar
Multicentric, retrospective study evaluating the epidemiologic characteristics and outcomes of patients aged 80years or older with non-small-cell lung cancer (NSCLC) harboring egfr mutations treated by EGFR-TKI
R. Corre, M. Labalette-Tiercin, A. Lespagnol, M. Denis +7 more
20140 citations
Semantic Scholar
Nomogram for Predicting Resistance to Sunitinib in Patients with Metastatic Clear Cell Renal Carcinoma
S. Kammerer-Jacquet, M. Belaud-Rotureau, E. Oger, G. Verhoest +6 more
20140 citations
Semantic Scholar
Clinical, immunohistochemical and genetic analysis of 50 thymic epithelial tumours managed in Rennes University Hospital between 2000 and 2011
M. Kerjouan, S. Jouneau, N. Choukeir, D. Chiforeanu +5 more
2013European Respiratory Journal0 citations
Semantic Scholar
C-kit, B-raf, and N-ras mutations in melanoma subtypes.
M. Pracht, Ariane Mogha, A. Fautrel, A. Lespagnol +5 more
20120 citations
Semantic Scholar

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