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R. J. Bende · SciRah

Researcher profile · Semantic Scholar

R. J. Bende

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R. J. Bende — researcher profile on SciRah

h-index: 28
Works: 77
Citations: 3,479

Most-cited papers

Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics
M. R. Klein, Card A. Van Baalen, A. M. Holwerda, Susana R. Kerkhof-Garde +6 more
1995Journal of Experimental Medicine729 citations Open access
Semantic Scholar
CD20 deficiency in humans results in impaired T cell-independent antibody responses.
T. Kuijpers, R. J. Bende, P. Baars, A. Grummels +7 more
2010Journal of Clinical Investigation375 citations Open access
Semantic Scholar
UvA-DARE ( Digital Academic Repository ) Among B cell non-Hodgkin ' s lymphomas , MALT lymphomas express a unique antibody repertoire with frequent rheumatoid factor reactivity
R. J. Bende, W. M. Aarts, R. Riedl, D. de Jong +2 more
2005186 citations
Semantic Scholar
The hepatocyte growth factor/Met pathway controls proliferation and apoptosis in multiple myeloma
P. Derksen, D. D. de Gorter, H. P. Meijer, R. J. Bende +5 more
2003Leukemia174 citations Open access
Semantic Scholar
A mutated B cell chronic lymphocytic leukemia subset that recognizes and responds to fungi
R. Hoogeboom, K. V. van Kessel, F. Hochstenbach, T. A. Wormhoudt +6 more
2013Journal of Experimental Medicine162 citations Open access
Semantic Scholar
IL-21 is expressed in Hodgkin lymphoma and activates STAT5: evidence that activated STAT5 is required for Hodgkin lymphomagenesis.
F. Scheeren, S. Diehl, L. Smit, T. Beaumont +7 more
2008Blood145 citations Open access
Semantic Scholar
Associations between HLA frequencies and pathogenic features of human immunodeficiency virus type 1 infection in seroconverters from the Amsterdam cohort of homosexual men.
M. R. Klein, I. Keet, Joe D'Amaro, R. J. Bende +6 more
1994Journal of Infectious Diseases117 citations
Semantic Scholar
Expression of activation-induced cytidine deaminase is confined to B-cell non-Hodgkin's lymphomas of germinal-center phenotype.
L. Smit, R. J. Bende, J. Aten, J. Guikema +2 more
2003Cancer Research113 citations
Semantic Scholar
The majority of cutaneous marginal zone B-cell lymphomas expresses class-switched immunoglobulins and develops in a T-helper type 2 inflammatory environment.
F. van Maldegem, R. V. van Dijk, T. A. Wormhoudt, P. Kluin +4 more
2008Blood103 citations Open access
Semantic Scholar
Primary follicular lymphoma of the small intestine: alpha4beta7 expression and immunoglobulin configuration suggest an origin from local antigen-experienced B cells.
R. J. Bende, L. Smit, Janneke G. Bossenbroek, W. M. Aarts +5 more
2003American Journal of Pathology101 citations Open access
Semantic Scholar
Germinal centers in human lymph nodes contain reactivated memory B cells
R. J. Bende, F. van Maldegem, M. Triesscheijn, T. A. Wormhoudt +2 more
2007Journal of Experimental Medicine84 citations Open access
Semantic Scholar
Variable heavy chain gene analysis of follicular lymphomas: correlation between heavy chain isotype expression and somatic mutation load.
W. M. Aarts, R. J. Bende, E. Steenbergen, Philip M. Kluin +3 more
2000Blood84 citations
Semantic Scholar
Chronic inflammatory disease, lymphoid tissue neogenesis and extranodal marginal zone B-cell lymphomas
R. J. Bende, F. van Maldegem, C. V. van Noesel
2009Haematologica78 citations Open access
Semantic Scholar
Among B cell non-Hodgkin's lymphomas, MALT lymphomas express a unique antibody repertoire with frequent rheumatoid factor reactivity
R. J. Bende, W. M. Aarts, R. Riedl, D. de Jong +2 more
2005Journal of Experimental Medicine73 citations Open access
Semantic Scholar
Comparison of human B cell antigen receptor complexes: membrane- expressed forms of immunoglobulin (Ig)M, IgD, and IgG are associated with structurally related heterodimers
C. V. van Noesel, G. Brouns, G. V. van Schijndel, R. J. Bende +3 more
1992Journal of Experimental Medicine54 citations Open access
Semantic Scholar
A novel chronic lymphocytic leukemia subset expressing mutated IGHV3-7-encoded rheumatoid factor B-cell receptors that are functionally proficient
R. Hoogeboom, T. A. Wormhoudt, M. Schipperus, A. Langerak +4 more
2013Leukemia50 citations Open access
Semantic Scholar
VH gene analysis of primary cutaneous B-cell lymphomas: evidence for ongoing somatic hypermutation and isotype switching.
W. M. Aarts, R. Willemze, R. J. Bende, C. J. Meijer +2 more
1998Blood50 citations
Semantic Scholar
VH Gene Analysis of Primary Cutaneous B-Cell Lymphomas: Evidence for Ongoing Somatic Hypermutation and Isotype Switching
W. M. Aarts, R. Willemze, R. J. Bende, C. Meijer +2 more
199846 citations
Semantic Scholar
Graft-versus-host-like disease complicating thymoma: lack of AIRE expression as a cause of non-hereditary autoimmunity?
G. Offerhaus, M. Schipper, A. Lazenby, E. Montgomery +5 more
2007Immunology Letters45 citations
Semantic Scholar
Variable heavy-chain gene analysis of follicular lymphomas: subclone selection rather than clonal evolution over time.
W. M. Aarts, R. J. Bende, Janneke G. Bossenbroek, S. Pals +1 more
2001Blood45 citations Open access
Semantic Scholar
Effects of IL-4, IL-5, and IL-6 on growth and immunoglobulin production of Epstein-Barr virus-infected human B cells.
R. J. Bende, G. Jochems, Thomas H. Frame, Michél R. Klein +3 more
1992Cellular Immunology45 citations
Semantic Scholar
Stereotypic Rheumatoid Factors That Are Frequently Expressed in Mucosa‐Associated Lymphoid Tissue–Type Lymphomas Are Rare in the Labial Salivary Glands of Patients With Sjögren's Syndrome
R. J. Bende, L. Slot, R. Hoogeboom, T. A. Wormhoudt +3 more
2015Arthritis & Rheumatology41 citations Open access
Semantic Scholar
Follicular Dendritic Cells Catalyze Hepatocyte Growth Factor (HGF) Activation in the Germinal Center Microenvironment by Secreting the Serine Protease HGF Activator
E. Tjin, R. J. Bende, P. Derksen, Anne-Pauline van Huijstee +3 more
2005Journal of Immunology38 citations Open access
Semantic Scholar
AKT signaling restrains tumor suppressive functions of FOXO transcription factors and GSK3 kinase in multiple myeloma.
Timon A. Bloedjes, G. de Wilde, C. Maas, E. Eldering +5 more
2020Blood Advances37 citations Open access
Semantic Scholar
Salivary Gland Mucosa‐Associated Lymphoid Tissue–Type Lymphoma From Sjögren’s Syndrome Patients in the Majority Express Rheumatoid Factors Affinity‐Selected for IgG
R. J. Bende, Jerry Janssen, Anna Beentjes, T. A. Wormhoudt +5 more
2020Arthritis & Rheumatology35 citations Open access
Semantic Scholar
The DNA Damage Response Regulates RAG1/2 Expression in Pre–B Cells through ATM-FOXO1 Signaling
Katarina Ochodnicka-Mackovicova, Mahnoush Bahjat, C. Maas, Amélie van der Veen +9 more
2016Journal of Immunology31 citations Open access
Semantic Scholar
Chlamydia psittaci-negative ocular adnexal marginal zone B-cell lymphomas have biased VH4-34 immunoglobulin gene expression and proliferate in a distinct inflammatory environment
F. van Maldegem, T. A. Wormhoudt, M. M. S. Mulder, M. E. Oud +8 more
2012Leukemia30 citations Open access
Semantic Scholar
Follicular lymphoma with a novel t(14;18) breakpoint involving the immunoglobulin heavy chain switch mu region indicates an origin from germinal center B cells.
J. Fenton, J. Vaandrager, W. M. Aarts, R. J. Bende +6 more
2002Blood29 citations Open access
Semantic Scholar
MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas
Marthe Minderman, Hildo C. Lantermans, Leonie J. Grüneberg, S. Cillessen +5 more
2023Blood Cancer Journal28 citations Open access
Semantic Scholar
Repertoire Analysis of B-Cells Located in Striated Ducts of Salivary Glands of Patients With Sjögren's Syndrome
A. Visser, G. Verstappen, B. van der Vegt, A. Vissink +4 more
2020Frontiers in Immunology27 citations Open access
Semantic Scholar
B-Lymphoblastic Lymphomas Evolving from Follicular Lymphomas Co-Express Surrogate Light Chains and Mutated Gamma Heavy Chains.
L. Slot, R. Hoogeboom, L. Smit, T. A. Wormhoudt +10 more
2016American Journal of Pathology25 citations Open access
Semantic Scholar
NF-κB and AKT signaling prevent DNA damage in transformed pre-B cells by suppressing RAG1/2 expression and activity.
Katarina Ochodnicka-Mackovicova, Mahnoush Bahjat, Timon A. Bloedjes, C. Maas +4 more
2015Blood24 citations Open access
Semantic Scholar
AKT supports the metabolic fitness of multiple myeloma cells by restricting FOXO activity
Timon A. Bloedjes, G. de Wilde, Gerarda H. Khan, T. Ashby +7 more
2022Blood Advances23 citations Open access
Semantic Scholar
Identification of a novel stereotypic IGHV4-59/IGHJ5-encoded B-cell receptor subset expressed by various B-cell lymphomas with high affinity rheumatoid factor activity
R. J. Bende, Jerry Janssen, T. A. Wormhoudt, K. Wagner +2 more
2016Haematologica22 citations Open access
Semantic Scholar
Lymphoma‐associated mutations in autoreactive memory B cells of patients with Sjögren's syndrome
R. J. Bende, L. Slot, M. Kwakkenbos, T. A. Wormhoudt +6 more
2022Journal of Pathology19 citations Open access
Semantic Scholar
Convergent evolution and B-cell recirculation in germinal centers in a human lymph node
A. Pélissier, Maria Stratigopoulou, N. Donner, E. Dimitriadis +4 more
2022Life Science Alliance18 citations Open access
Semantic Scholar
Acquisition of N-Glycosylation Sites in Immunoglobulin Heavy Chain Genes During Local Expansion in Parotid Salivary Glands of Primary Sjögren Patients
A. Visser, M. Doorenspleet, N. de Vries, F. Spijkervet +5 more
2018Frontiers in Immunology17 citations Open access
Semantic Scholar
AID splice variants lack deaminase activity.
F. van Maldegem, F. Scheeren, R. A. Jibodh, R. J. Bende +2 more
2009Blood17 citations Open access
Semantic Scholar
Quantitative RT-PCR analysis of activation-induced cytidine deaminase expression in tissue samples from mantle cell lymphoma and B-cell chronic lymphocytic leukemia patients.
J. Guikema, S. Rosati, K. Akkermans, R. J. Bende +5 more
2005Blood16 citations
Semantic Scholar
In situ analysis of the variable heavy chain gene of an IgM/IgG-expressing follicular lymphoma: evidence for interfollicular trafficking of tumor cells.
W. M. Aarts, R. J. Bende, J. Vaandrager, P. Kluin +3 more
2002American Journal of Pathology16 citations Open access
Semantic Scholar
MALT lymphoma-derived rheumatoid factors are nonpolyreactive high-affinity antibodies.
R. Hoogeboom, R. J. Bende, C. V. van Noesel
2010Blood15 citations
Semantic Scholar
Immunoglobulin diversification in B cell malignancies: internal splicing of heavy chain variable region as a by-product of somatic hypermutation
R. J. Bende, W. M. Aarts, S. Pals, C. V. van Noesel
2002Leukemia15 citations Open access
Semantic Scholar
Biased Igλ expression in hypermutated IgD multiple myelomas does not result from receptor revision
M. V. D. van der Burg, R. J. Bende, W. M. Aarts, A. Langerak +2 more
2002Leukemia14 citations Open access
Semantic Scholar
The NEDD8-activating enzyme inhibitor MLN4924 induces DNA damage in Ph+ leukemia and sensitizes for ABL kinase inhibitors
Mahnoush Bahjat, G. de Wilde, Tijmen P. van Dam, C. Maas +7 more
2019Cell Cycle11 citations Open access
Semantic Scholar
In vitro induction of antibody secretion of primary B-cell chronic lymphocytic leukaemia cells
R. Hoogeboom, Roy J. A. Reinten, J. Schot, Jeroen E. J. Guikema +2 more
2014Leukemia11 citations Open access
Semantic Scholar
Activation-Induced Cytidine Deaminase Splice Variants Are Defective Because of the Lack of Structural Support for the Catalytic Site
F. van Maldegem, R. A. Jibodh, R. V. van Dijk, R. J. Bende +1 more
2010Journal of Immunology11 citations Open access
Semantic Scholar
Antigen receptors and somatic hypermutation in B-cell chronic lymphocytic leukemia with Richter's transformation.
L. Smit, F. van Maldegem, A. Langerak, C. Ellen van der Schoot +5 more
2006Haematologica11 citations
Semantic Scholar
Analysis of variable heavy and light chain genes in follicular lymphomas of different heavy chain isotype.
W. M. Aarts, R. J. Bende, S. Pals, C. V. van Noesel
1999Current Topics in Microbiology and Immunology6 citations
Semantic Scholar
DNA polymerase β prevents AID-instigated mutagenic non-canonical mismatch DNA repair
Mahnoush Bahjat, Maria Stratigopoulou, B. Pilzecker, Tijmen P. van Dam +5 more
2020bioRxiv5 citations Open access
Semantic Scholar
De novo gene mutations in normal human memory B cells
L. Slot, T. A. Wormhoudt, M. Kwakkenbos, K. Wagner +6 more
2018Leukemia5 citations Open access
Semantic Scholar

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C. V. van Noesel — researcher profile on SciRah
J. Guikema×14
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J. Guikema — researcher profile on SciRah
W. M. Aarts×13
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