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C. Porter · SciRah

Researcher profile · Semantic Scholar

C. Porter

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C. Porter — researcher profile on SciRah

h-index: 76
Works: 279
Citations: 24K

Most-cited papers

Minimum Information Reporting in Bio–Nano Experimental Literature
Matthew Faria, M. Björnmalm, K. Thurecht, S. Kent +15 more
2018Nature Nanotechnology655 citations Open access
Semantic Scholar
50years of oral lipid-based formulations: Provenance, progress and future perspectives.
O. Feeney, M. Crum, C. McEvoy, Natalie L. Trevaskis +5 more
2016Advanced Drug Delivery Reviews361 citations Open access
Semantic Scholar
The mechanisms of pharmacokinetic food-drug interactions - A perspective from the UNGAP group.
M. Koziolek, S. Alcaro, P. Augustijns, A. Basit +20 more
2019European Journal of Pharmaceutical Sciences307 citations Open access
Semantic Scholar
Neurokinin 1 receptor signaling in endosomes mediates sustained nociception and is a viable therapeutic target for prolonged pain relief
D. Jensen, T. Lieu, M. Halls, N. Veldhuis +22 more
2017Science Translational Medicine206 citations Open access
Semantic Scholar
Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission
R. E. Yarwood, Wendy L. Imlach, T. Lieu, N. Veldhuis +13 more
2017Proceedings of the National Academy of Sciences of the United States of America171 citations Open access
Semantic Scholar
Computational prediction of formulation strategies for beyond-rule-of-5 compounds.
Christel A. S. Bergström, W. Charman, C. Porter
2016Advanced Drug Delivery Reviews158 citations Open access
Semantic Scholar
Protease-activated receptor-2 in endosomes signals persistent pain of irritable bowel syndrome
N. Jiménez-Vargas, Luke A. Pattison, Pei-Shen Zhao, T. Lieu +23 more
2018Proceedings of the National Academy of Sciences of the United States of America156 citations Open access
Semantic Scholar
Size and rigidity of cylindrical polymer brushes dictate long circulating properties in vivo.
M. Müllner, Sarah J. Dodds, Tri-Hung Nguyen, D. Senyschyn +3 more
2015ACS Nano144 citations Open access
Semantic Scholar
Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy
Eunice E. To, R. Vlahos, Raymond Luong, M. Halls +16 more
2017Nature Communications140 citations Open access
Semantic Scholar
Current challenges and future perspectives in oral absorption research: An opinion of the UNGAP network.
Z. Vinarov, B. Abrahamsson, P. Artursson, H. Batchelor +32 more
2021Advanced Drug Delivery Reviews134 citations Open access
Semantic Scholar
Mesenteric lymphatic dysfunction promotes insulin resistance and represents a potential treatment target in obesity
En-Yuan Cao, M. Watt, C. Nowell, T. Quach +19 more
2021Nature Metabolism94 citations Open access
Semantic Scholar
Tools for Early Prediction of Drug Loading in Lipid-Based Formulations
Linda C. Alskär, C. Porter, Christel A. S. Bergström
2015Molecular Pharmaceutics90 citations Open access
Semantic Scholar
Fatty Acid-Binding Protein 5 at the Blood–Brain Barrier Regulates Endogenous Brain Docosahexaenoic Acid Levels and Cognitive Function
Yi-Jun Pan, J. Short, Kwok H. C. Choy, An-Nie X. Zeng +5 more
2016Journal of Neuroscience80 citations Open access
Semantic Scholar
Glyceride-Mimetic Prodrugs Incorporating Self-Immolative Spacers Promote Lymphatic Transport, Avoid First-Pass Metabolism, and Enhance Oral Bioavailability.
Luojuan Hu, T. Quach, Sifei Han, S. Lim +5 more
2016Angewandte Chemie72 citations Open access
Semantic Scholar
Toward the Establishment of Standardized In Vitro Tests for Lipid-Based Formulations. 5. Lipolysis of Representative Formulations by Gastric Lipase
Jean-Claude Bakala-N’Goma, H. Williams, P. Sassene, Karen Kleberg +14 more
2015Pharmaceutical Research67 citations
Semantic Scholar
Impact of Drug Physicochemical Properties on Lipolysis-Triggered Drug Supersaturation and Precipitation from Lipid-Based Formulations
Linda C. Alskär, Janneke Keemink, Jenny Johannesson, C. Porter +1 more
2018Molecular Pharmaceutics62 citations Open access
Semantic Scholar
Ionic Liquid Forms of Weakly Acidic Drugs in Oral Lipid Formulations: Preparation, Characterization, in Vitro Digestion, and in Vivo Absorption Studies.
Yasemin Şahbaz, Tri-Hung Nguyen, Leigh Ford, C. McEvoy +3 more
2017Molecular Pharmaceutics61 citations Open access
Semantic Scholar
Lipids in the Stomach – Implications for the Evaluation of Food Effects on Oral Drug Absorption
M. Koziolek, F. Carrière, C. Porter
2018Pharmaceutical Research57 citations Open access
Semantic Scholar
Enhancing the Oral Absorption of Kinase Inhibitors Using Lipophilic Salts and Lipid-Based Formulations.
H. Williams, Leigh Ford, Sifei Han, K. J. Tangso +7 more
2018Molecular Pharmaceutics56 citations Open access
Semantic Scholar
Unlocking the full potential of lipid-based formulations using lipophilic salt/ionic liquid forms.
H. Williams, Leigh Ford, A. Igonin, Zhenhua Shan +7 more
2019Advanced Drug Delivery Reviews54 citations Open access
Semantic Scholar
Polymeric Precipitation Inhibitors Promote Fenofibrate Supersaturation and Enhance Drug Absorption from a Type IV Lipid-Based Formulation.
Estelle J A Suys, David K. Chalmers, C. Pouton, C. Porter
2018Molecular Pharmaceutics54 citations Open access
Semantic Scholar
Transformation of Biopharmaceutical Classification System Class I and III Drugs Into Ionic Liquids and Lipophilic Salts for Enhanced Developability Using Lipid Formulations.
H. Williams, Leigh Ford, S. Lim, Sifei Han +8 more
2018Journal of Pharmacy and Science54 citations Open access
Semantic Scholar
Fatty Acid-binding Proteins 1 and 2 Differentially Modulate the Activation of Peroxisome Proliferator-activated Receptor α in a Ligand-selective Manner*
M. L. R. Hughes, Bo-Nan Liu, M. Halls, K. Wagstaff +6 more
2015Journal of Biological Chemistry54 citations Open access
Semantic Scholar
The mesenteric lymph duct cannulated rat model: application to the assessment of intestinal lymphatic drug transport.
Natalie L. Trevaskis, Luojuan Hu, S. Caliph, Sifei Han +1 more
2015Journal of Visualized Experiments54 citations Open access
Semantic Scholar
Smart design approaches for orally administered lipophilic prodrugs to promote lymphatic transport.
Aurelia S. Elz, Natalie L. Trevaskis, C. Porter, J. Bowen +1 more
2021Journal of Controlled Release53 citations
Semantic Scholar
Pointing in the Right Direction: Controlling the Orientation of Proteins on Nanoparticles Improves Targeting Efficiency.
Ken W. Yong, D. Yuen, Moore Z. Chen, C. Porter +1 more
2019Nano letters (Print)51 citations Open access
Semantic Scholar
Methotrexate-conjugated PEGylated dendrimers show differential patterns of deposition and activity in tumor-burdened lymph nodes after intravenous and subcutaneous administration in rats.
L. Kaminskas, Victoria M Mcleod, D. Ascher, Gemma M. Ryan +12 more
2015Molecular Pharmaceutics50 citations
Semantic Scholar
Reducing Dendrimer Generation and PEG Chain Length Increases Drug Release and Promotes Anticancer Activity of PEGylated Polylysine Dendrimers Conjugated with Doxorubicin via a Cathepsin-Cleavable Peptide Linker.
Dharmini C. Mehta, Nathania J. Leong, Victoria M Mcleod, B. Kelly +4 more
2018Molecular Pharmaceutics48 citations Open access
Semantic Scholar
Lipophilic Conjugates of Drugs: A Tool to Improve Drug Pharmacokinetic and Therapeutic Profiles
Sifei Han, Lianghe Mei, T. Quach, C. Porter +1 more
2021Pharmaceutical Research45 citations Open access
Semantic Scholar
Cyclic peptide-poly(HPMA) nanotubes as drug delivery vectors: In vitro assessment, pharmacokinetics and biodistribution.
Sophie C. Larnaudie, Joaquin Sanchis, Tri-Hung Nguyen, Raoul Peltier +5 more
2018Biomaterials45 citations Open access
Semantic Scholar
Gel-Mediated Electrospray Assembly of Silica Supraparticles for Sustained Drug Delivery.
Yutian Ma, M. Björnmalm, A. Wise, Christina Cortez-Jugo +8 more
2018ACS Applied Materials and Interfaces42 citations Open access
Semantic Scholar
Lymphatic uptake of liposomes after intraperitoneal administration primarily occurs via the diaphragmatic lymphatics and is dependent on liposome surface properties.
Given Lee, Sifei Han, I. Inocencio, En-Yuan Cao +5 more
2019Molecular Pharmaceutics40 citations Open access
Semantic Scholar
Intestinal Lymph Flow, and Lipid and Drug Transport Scale Allometrically From Pre-clinical Species to Humans
Natalie L. Trevaskis, Given Lee, Alistair Escott, K. L. Phang +9 more
2020Frontiers in Physiology36 citations Open access
Semantic Scholar
Ionic Liquid Forms of the Antimalarial Lumefantrine in Combination with LFCS Type IIIB Lipid-Based Formulations Preferentially Increase Lipid Solubility, In Vitro Solubilization Behavior and In Vivo Exposure
Erin Tay, Tri-Hung Nguyen, Leigh Ford, H. Williams +3 more
2019Pharmaceutics36 citations Open access
Semantic Scholar
Lymphatic Transport and Lymphocyte Targeting of a Triglyceride Mimetic Prodrug Is Enhanced in a Large Animal Model: Studies in Greyhound Dogs.
Sifei Han, Luojuan Hu, Gracia, T. Quach +4 more
2016Molecular Pharmaceutics36 citations Open access
Semantic Scholar
Profiling the Role of Deacylation-Reacylation in the Lymphatic Transport of a Triglyceride-Mimetic Prodrug
Sifei Han, Luojuan Hu, T. Quach, J. Simpson +2 more
2015Pharmaceutical Research36 citations
Semantic Scholar
Targeting immune cells within lymph nodes
C. Porter, Natalie L. Trevaskis
2020Nature Nanotechnology35 citations Open access
Semantic Scholar
Hyaluronic Acid Molecular Weight Determines Lung Clearance and Biodistribution after Instillation
Christopher Kuehl, Ti Zhang, L. Kaminskas, C. Porter +3 more
2016Molecular Pharmaceutics34 citations Open access
Semantic Scholar
High density lipoprotein composition influences lymphatic transport after subcutaneous administration.
Gracia Gracia, En-Yuan Cao, O. Feeney, A. Johnston +2 more
2020Molecular Pharmaceutics32 citations Open access
Semantic Scholar
Effect of increased surface hydrophobicity via drug conjugation on the clearance of inhaled PEGylated polylysine dendrimers
Shadabul Haque, Victoria M Mcleod, Seth A. Jones, Sandy Fung +6 more
2017European journal of pharmaceutics and biopharmaceutics32 citations Open access
Semantic Scholar
Computational Models of the Gastrointestinal Environment. 2. Phase Behavior and Drug Solubilization Capacity of a Type I Lipid-Based Drug Formulation after Digestion.
Woldeamanuel A. Birru, Dallas B. Warren, Sifei Han, H. Benameur +3 more
2017Molecular Pharmaceutics32 citations
Semantic Scholar
Spatial Properties of Reactive Oxygen Species Govern Pathogen-Specific Immune System Responses
Eunice E. To, J. O'Leary, L. O'Neill, R. Vlahos +5 more
2020Antioxidants and Redox Signaling30 citations Open access
Semantic Scholar
Engineering Biocoatings To Prolong Drug Release from Supraparticles.
Yutian Ma, Christina Cortez-Jugo, Jianhua Li, Zhi-Xing Lin +9 more
2019Biomacromolecules30 citations Open access
Semantic Scholar
A Nonionic Polyethylene Oxide (PEO) Surfactant Model: Experimental and Molecular Dynamics Studies of Kolliphor EL.
Estelle J A Suys, Dallas B. Warren, Anna C. Pham, C. Nowell +5 more
2019Journal of Pharmacy and Science29 citations Open access
Semantic Scholar
Optimal PEGylation can improve the exposure of interferon in the lungs following pulmonary administration.
Victoria M Mcleod, L. Chan, Gemma M. Ryan, C. Porter +1 more
2015Journal of Pharmacy and Science29 citations
Semantic Scholar
Lymph-directed immunotherapy - Harnessing endogenous lymphatic distribution pathways for enhanced therapeutic outcomes in cancer.
O. Feeney, Gracia Gracia, D. H. Brundel, Natalie L. Trevaskis +3 more
2020Advanced Drug Delivery Reviews26 citations Open access
Semantic Scholar
Computational Models of the Gastrointestinal Environment. 1. The Effect of Digestion on the Phase Behavior of Intestinal Fluids.
Woldeamanuel A. Birru, Dallas B. Warren, S. Headey, H. Benameur +3 more
2017Molecular Pharmaceutics26 citations Open access
Semantic Scholar
Lymphatic transport and lymph node targeting of methotrexate-conjugated PEGylated dendrimers are enhanced by reducing the length of the drug linker or masking interactions with the injection site.
Gemma M. Ryan, Victoria M Mcleod, Dharmini C. Mehta, B. Kelly +4 more
2017Nanomedicine: Nanotechnology, Biology and Medicine25 citations Open access
Semantic Scholar
Conjugation of 10 kDa Linear PEG onto Trastuzumab Fab' Is Sufficient to Significantly Enhance Lymphatic Exposure while Preserving in Vitro Biological Activity.
L. Chan, D. Ascher, Rajbharan Yadav, J. Bulitta +4 more
2016Molecular Pharmaceutics25 citations Open access
Semantic Scholar
Targeted delivery of mycophenolic acid to the mesenteric lymph node using a triglyceride mimetic prodrug approach enhances gut-specific immunomodulation in mice.
Ruby Kochappan, En-Yuan Cao, Sifei Han, Luojuan Hu +15 more
2021Journal of Controlled Release24 citations Open access
Semantic Scholar

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