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S. Headey · SciRah

Researcher profile · Semantic Scholar

S. Headey

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S. Headey — researcher profile on SciRah

h-index: 22
Works: 75
Citations: 1,229

Most-cited papers

IGF-binding proteins--the pieces are falling into place.
L. Bach, S. Headey, R. Norton
2005Trends in endocrinology and metabolism172 citations
Semantic Scholar
Small heat-shock proteins interact with a flanking domain to suppress polyglutamine aggregation
A. L. Robertson, S. Headey, Helen Saunders, H. Ecroyd +3 more
2010Proceedings of the National Academy of Sciences of the United States of America83 citations Open access
Semantic Scholar
Parallel Screening of Low Molecular Weight Fragment Libraries
J. Wielens, S. Headey, D. Rhodes, R. Mulder +7 more
2013Journal of biomolecular screening76 citations Open access
Semantic Scholar
Enhanced Homology-directed Repair for Highly Efficient Gene Editing in Hematopoietic Stem/Progenitor Cells.
S. D. de Ravin, J. Brault, R. Meis, Siyuan Liu +19 more
2021Blood62 citations Open access
Semantic Scholar
Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module
J. Selkrig, M. Belousoff, S. Headey, E. Heinz +10 more
2015Scientific Reports58 citations Open access
Semantic Scholar
Application of fragment-based screening to the design of inhibitors of Escherichia coli DsbA.
L. Adams, Pooja Sharma, B. Mohanty, O. Ilyichova +16 more
2015Angewandte Chemie54 citations Open access
Semantic Scholar
Structural basis for the inhibition of poxvirus assembly by the antibiotic rifampicin
D. Garriga, S. Headey, C. Accurso, M. Gunzburg +2 more
2018Proceedings of the National Academy of Sciences of the United States of America51 citations Open access
Semantic Scholar
C-terminal domain of insulin-like growth factor (IGF) binding protein-6: structure and interaction with IGF-II.
S. Headey, David W Keizer, S. Yao, Geoffrey Brasier +3 more
2004Molecular Endocrinology49 citations Open access
Semantic Scholar
Crystal structure of the HIV‐1 integrase core domain in complex with sucrose reveals details of an allosteric inhibitory binding site
J. Wielens, S. Headey, D. Jeevarajah, D. Rhodes +4 more
2010FEBS Letters45 citations
Semantic Scholar
Contributions of the N- and C-terminal domains of IGF binding protein-6 to IGF binding.
S. Headey, K. S. Leeding, R. Norton, L. Bach
2004Journal of Molecular Endocrinology43 citations Open access
Semantic Scholar
Evolutionary Differences in the Vegf/Vegfr Code Reveal Organotypic Roles for the Endothelial Cell Receptor Kdr in Developmental Lymphangiogenesis.
Adam J. Vogrin, N. I. Bower, M. Gunzburg, S. Roufail +6 more
2019Cell Reports35 citations Open access
Semantic Scholar
Binding site for the C‐domain of insulin‐like growth factor (IGF) binding protein‐6 on IGF‐II; implications for inhibition of IGF actions
S. Headey, David W Keizer, S. Yao, J. Wallace +2 more
2004FEBS Letters35 citations
Semantic Scholar
Δ-Myrtoxin-Mp1a is a Helical Heterodimer from the Venom of the Jack Jumper Ant that has Antimicrobial, Membrane-Disrupting, and Nociceptive Activities.
Zoltan Dekan, S. Headey, M. Scanlon, B. Baldo +9 more
2017Angewandte Chemie34 citations Open access
Semantic Scholar
Characterization of two distinct modes of drug binding to human intestinal fatty acid binding protein.
R. Patil, Aisha Laguerre, J. Wielens, S. Headey +5 more
2014ACS Chemical Biology34 citations Open access
Semantic Scholar
Distinct binding properties of TIAR RRMs and linker region
Henry S. Kim, S. Headey, Yano M. K. Yoga, M. Scanlon +3 more
2013RNA Biology33 citations Open access
Semantic Scholar
Molecular dissection of an inhibitor targeting the HIV integrase dependent preintegration complex nuclear import
K. Wagstaff, S. Headey, S. Telwatte, D. Tyssen +4 more
2018Cellular Microbiology29 citations Open access
Semantic Scholar
Computational Models of the Gastrointestinal Environment. 1. The Effect of Digestion on the Phase Behavior of Intestinal Fluids.
Woldeamanuel A. Birru, Dallas B. Warren, S. Headey, H. Benameur +3 more
2017Molecular Pharmaceutics26 citations Open access
Semantic Scholar
The Structure of Integrin α1I Domain in Complex with a Collagen-mimetic Peptide*
Yan-Ni K. Y. Chin, S. Headey, B. Mohanty, R. Patil +6 more
2013Journal of Biological Chemistry25 citations Open access
Semantic Scholar
A ligand-induced structural change in fatty acid–binding protein 1 is associated with potentiation of peroxisome proliferator–activated receptor α agonists
R. Patil, B. Mohanty, Bo-Nan Liu, I. Chandrashekaran +11 more
2018Journal of Biological Chemistry24 citations Open access
Semantic Scholar
Fragment‐Based Design of Ligands Targeting a Novel Site on the Integrase Enzyme of Human Immunodeficiency Virus 1
J. Wielens, S. Headey, J. Deadman, D. Rhodes +3 more
2011ChemMedChem24 citations
Semantic Scholar
A picornaviral loop-to-loop replication complex
Jolyon K. Claridge, S. Headey, John Y. H. Chow, M. Schwalbe +5 more
2009Journal of Structural Biology24 citations Open access
Semantic Scholar
Identification of mechanistically distinct inhibitors of HIV-1 reverse transcriptase through fragment screening
J. La, C. F. Latham, Ricky N Tinetti, Adam Johnson +7 more
2015Proceedings of the National Academy of Sciences of the United States of America23 citations Open access
Semantic Scholar
Fragment-Based Discovery of Inhibitors of the Bacterial DnaG-SSB Interaction
Zorik Chilingaryan, S. Headey, A. T. Lo, Zhi-Qiang Xu +4 more
2018Antibiotics18 citations Open access
Semantic Scholar
Solution Structure of the Squash Aspartic Acid Proteinase Inhibitor (SQAPI) and Mutational Analysis of Pepsin Inhibition
S. Headey, U. K. Macaskill, Michele A. Wright, Jolyon K. Claridge +5 more
2010Journal of Biological Chemistry16 citations Open access
Semantic Scholar
C-terminal domain of insulin-like growth factor (IGF) binding protein 6: conformational exchange and its correlation with IGF-II binding.
S. Yao, S. Headey, David W Keizer, L. Bach +1 more
2004Biochemistry16 citations
Semantic Scholar
Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1
B. Mohanty, K. Rimmer, R. McMahon, S. Headey +8 more
2017PLoS ONE15 citations Open access
Semantic Scholar
Protein unfolding is essential for cleavage within the α-helix of a model protein substrate by the serine protease, thrombin.
A. L. Robertson, S. Headey, N. Ng, L. Wijeyewickrema +3 more
2016Biochimie15 citations
Semantic Scholar
NMR structure of stem-loop D from human rhinovirus-14.
S. Headey, He Huang, Jolyon K. Claridge, G. A. Soares +4 more
2007RNA: A publication of the RNA Society15 citations Open access
Semantic Scholar
Structure of the Chicken CD3ϵδ/γ Heterodimer and Its Assembly with the αβT Cell Receptor*
Richard Berry, S. Headey, M. J. Call, J. McCluskey +6 more
2014Journal of Biological Chemistry14 citations Open access
Semantic Scholar
Structural and biochemical insights into the disulfide reductase mechanism of DsbD, an essential enzyme for neisserial pathogens
Roxanne P. Smith, B. Mohanty, S. Mowlaboccus, J. Paxman +8 more
2018Journal of Biological Chemistry9 citations Open access
Semantic Scholar
Ligand-enhanced expression and in-cell assay of human peroxisome proliferator-activated receptor alpha ligand binding domain.
T. Velkov, K. Rimmer, S. Headey
2010Protein Expression and Purification9 citations
Semantic Scholar
Detection and Prevention of Aggregation-based False Positives in STD-NMR-based Fragment Screening
Amelia Vom, S. Headey, Geqing Wang, B. Capuano +3 more
20138 citations
Semantic Scholar
Cyclic Hexapeptide Mimics of the LEDGF Integrase Recognition Loop in Complex with HIV‐1 Integrase
Susan E. Northfield, J. Wielens, S. Headey, Billy J. Williams-Noonan +5 more
2018ChemMedChem7 citations Open access
Semantic Scholar
C-terminal domain of insulin-like growth factor binding protein-6: structure and interaction with insulin-like growth factor-II
S. Headey, David W Keizer, S. Yao, P. Kantharidis +3 more
20046 citations
Semantic Scholar
Letter to the Editor: 1H, 13C and 15N resonance assignments of the C-terminal domain of insulin-like growth factor binding protein-6 (IGFBP-6)
S. Headey, S. Yao, N. Parker, P. Kantharidis +2 more
2003Journal of Biomolecular NMR6 citations
Semantic Scholar
Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra-Terminal Domain.
Luke A Adams, Lorna Wilkinson-White, M. Gunzburg, S. Headey +5 more
2023Journal of Medicinal Chemistry5 citations Open access
Semantic Scholar
NMR case study of ropinirole: concentration‐dependent effects of nonexchangeable proton resonances
Manuela Jörg, S. Headey, Peter J. Scammells, B. Capuano
2014Magnetic resonance in chemistry : MRC5 citations Open access
Semantic Scholar
Colloidal characteristics and formulation of pure protein particulate vaccines
P. White, Pascal L. C. Hickey, Linda Sze Tu, S. Headey +3 more
2012The Journal of pharmacy and pharmacology5 citations
Semantic Scholar
The Structure of Inequality
B. Headey, S. Headey, R. Muffels
20015 citations
Semantic Scholar
Targeting HIV-1 Reverse Transcriptase Using a Fragment-Based Approach
Mahta Mansouri, Shawn Rumrill, S. Dawson, Adam Johnson +14 more
2023Molecules4 citations Open access
Semantic Scholar
Assignments of human integrin α1I domain in the apo and Mg2+ bound states
Yan-Ni K. Y. Chin, S. Headey, B. Mohanty, J. Emsley +2 more
2013Biomolecular NMR Assignments4 citations
Semantic Scholar
Blind man's bluff - Elaboration of fragment hits in the absence of structure for the development of antitrypsin deficiency inhibitors
S. Headey, M. C. Pearce, M. Scanlon, S. Bottomley
20133 citations
Semantic Scholar
Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra Terminal Domain
L. Adams, Lorna Wilkinson-White, M. Gunzburg, S. Headey +4 more
20202 citations Open access
Semantic Scholar
TUDOR DOMAIN OF TUMOR SUPPRESSOR P53BP1 WITH MFP-6008
J. The, Z. Hong, A. Dong, S. Headey +7 more
20202 citations
Semantic Scholar
Solution structure and DNA binding of the catalytic domain of the large serine resolvase TnpX
S. Headey, A. Sivakumaran, V. Adams, D. Lyras +3 more
2015Journal of Molecular Recognition2 citations Open access
Semantic Scholar
Fragment-Based Design of Ligands Targeting a Novel Site on the Integrase Enzyme of Human Immunodeficiency Virus 1 (vol 6, pg 258, 2011)
J. Wielens, S. Headey, J. Deadman, D. Rhodes +4 more
20112 citations
Semantic Scholar
Backbone assignments of the 34 kDa ketopantoate reductase from E. coli
S. Headey, Amelia Vom, J. Simpson, M. Scanlon
2008Biomolecular NMR Assignments2 citations
Semantic Scholar
Who Enjoys the Fruits of Growth? Impact of Governments and Markets on Living Standards in Germany, The Netherlands and the U.S.A., 1987–1996
B. Headey, S. Headey, R. Muffels, Colin R. Janssen
20041 citations
Semantic Scholar
Using 4-HPP and PP as Substrates to Assess Purified MIF and D-DT Tautomerase Activity and Inhibition.
Emmanuel K Yeboah, Samie Elmazi, S. Headey, Natalie A Borg
2026Methods in molecular biology0 citations
Semantic Scholar
Expression and Purification of Recombinant Macrophage Migration Inhibitory Factor (MIF).
Samie Elmazi, Emmanuel K Yeboah, S. Headey, Natalie A Borg
2026Methods in molecular biology0 citations
Semantic Scholar

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