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Kailin Yang · SciRah

Researcher profile · Semantic Scholar

Kailin Yang

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Kailin Yang — researcher profile on SciRah

h-index: 42
Works: 116
Citations: 10K

Most-cited papers

Structure of Mpro from SARS-CoV-2 and discovery of its inhibitors
Zhenming Jin, Xiaoyu Du, Yechun Xu, Yong-Qiang Deng +27 more
2020Nature3,606 citations Open access
Semantic Scholar
Structure of Mpro from COVID-19 virus and discovery of its inhibitors
Zhenming Jin, Xiaoyu Du, Yechun Xu, Yongqiang Deng +27 more
2020bioRxiv530 citations Open access
Semantic Scholar
Mitochondrial Control by DRP1 in Brain Tumor Initiating Cells
Qi Xie, Qiulian Wu, C. Horbinski, William A. Flavahan +10 more
2015Nature Neuroscience383 citations Open access
Semantic Scholar
Structural basis for the inhibition of SARS-CoV-2 main protease by antineoplastic drug carmofur
Zhenming Jin, Yao Zhao, Yuan-Yuan Sun, Bing Zhang +17 more
2020Nature Structural & Molecular Biology348 citations Open access
Semantic Scholar
Antigen presentation in cancer — mechanisms and clinical implications for immunotherapy
Kailin Yang, A. Halima, T. Chan
2023Nature Reviews Clinical Oncology306 citations
Semantic Scholar
Reciprocal signaling between Glioblastoma Stem Cells and Differentiated Tumor Cells Promotes Malignant Progression
Xiu-Xing Wang, B. Prager, Qiulian Wu, Leo J Y Kim +25 more
2018Cell Stem Cell233 citations Open access
Semantic Scholar
Lysine Catabolism Reprograms Tumour Immunity through Histone Crotonylation
Huairui Yuan, Xujia Wu, Qiulian Wu, Adam Chatoff +14 more
2023Nature231 citations Open access
Semantic Scholar
Crystal structure of SARS-CoV-2 main protease in complex with protease inhibitor PF-07321332
Yao Zhao, Chao Fang, Qi Zhang, Ruxue Zhang +14 more
2021Protein & Cell200 citations Open access
Semantic Scholar
Purine synthesis promotes maintenance of brain tumor initiating cells in glioma
Xiu-Xing Wang, Kailin Yang, Qi Xie, Qiulian Wu +18 more
2017Nature Neuroscience189 citations Open access
Semantic Scholar
Structure of Main Protease from Human Coronavirus NL63: Insights for Wide Spectrum Anti-Coronavirus Drug Design
Fenghua Wang, Cheng Chen, Wenjie Tan, Kailin Yang +1 more
2016Scientific Reports178 citations Open access
Semantic Scholar
Targeting pyrimidine synthesis accentuates molecular therapy response in glioblastoma stem cells
Xiu-Xing Wang, Kailin Yang, Qiulian Wu, Leo J Y Kim +18 more
2019Science Translational Medicine172 citations Open access
Semantic Scholar
Deubiquitinase USP13 maintains glioblastoma stem cells by antagonizing FBXL14-mediated Myc ubiquitination
X. Fang, Wenchao Zhou, Qiulian Wu, Zhi Huang +13 more
2017Journal of Experimental Medicine143 citations Open access
Semantic Scholar
Structural basis for replicase polyprotein cleavage and substrate specificity of main protease from SARS-CoV-2
Yao Zhao, Yan Zhu, Xiang Liu, Zhenming Jin +15 more
2022Proceedings of the National Academy of Sciences of the United States of America140 citations Open access
Semantic Scholar
High-throughput screening identifies established drugs as SARS-CoV-2 PLpro inhibitors
Yao Zhao, Xiaoyu Du, Yinkai Duan, Xiaoyan Pan +22 more
2021Protein & Cell130 citations Open access
Semantic Scholar
Brain cancer stem cells: resilience through adaptive plasticity and hierarchical heterogeneity
R. Gimple, Kailin Yang, Matthew E. Halbert, S. Agnihotri +1 more
2022Nature Reviews. Cancer112 citations
Semantic Scholar
MYC-regulated Mevalonate Metabolism Maintains Brain Tumor Initiating Cells
Xiu-Xing Wang, Zhi Huang, Qiulian Wu, B. Prager +17 more
2017Cancer Research110 citations Open access
Semantic Scholar
Immunometabolic rewiring in tumorigenesis and anti-tumor immunotherapy
Xin Lian, Kailin Yang, Ren-Liang Li, Mao-Mao Li +5 more
2022Molecular Cancer104 citations Open access
Semantic Scholar
Recent Progress in the Drug Development Targeting SARS-CoV-2 Main Protease as Treatment for COVID-19
Wen Cui, Kailin Yang, Haitao Yang
2020Frontiers in Molecular Biosciences96 citations Open access
Semantic Scholar
β2-microglobulin maintains glioblastoma stem cells and induces M2-like polarization of tumor-associated macrophages.
Da-Qi Li, Qian Zhang, Lu Li, Kexin Chen +32 more
2022Cancer Research87 citations Open access
Semantic Scholar
Mechanisms of activation and inhibition of Zika virus NS2B-NS3 protease
Xia Chen, Kailin Yang, Chen Wu, Cheng Chen +6 more
2016Cell Research87 citations Open access
Semantic Scholar
Structure-based drug design, virtual screening and high-throughput screening rapidly identify antiviral leads targeting COVID-19
Zhenming Jin, Xiaoyu Du, Yechun Xu, Yong-Qiang Deng +25 more
202084 citations
Semantic Scholar
Structural basis of Zika virus helicase in recognizing its substrates
H. Tian, Xiaoyun Ji, Xiao-Yun Yang, Zhong-yin Zhang +11 more
2016Protein & Cell81 citations Open access
Semantic Scholar
The crystal structure of Zika virus helicase: basis for antiviral drug design
H. Tian, Xiaoyun Ji, Xiao-Yun Yang, Wei Xie +7 more
2016Protein & Cell79 citations Open access
Semantic Scholar
PDGF Signaling Inhibits Mitophagy in Glioblastoma Stem Cells through N6-methyladenosine
D. Lv, R. Gimple, Cuiqing Zhong, Qiulian Wu +14 more
2022Developmental Cell76 citations Open access
Semantic Scholar
Targeting Microglial Metabolic Rewiring Synergizes with Immune Checkpoint Blockade Therapy for Glioblastoma
Zengpanpan Ye, Xiao-Lin Ai, Kailin Yang, Zheng-Nan Yang +24 more
2023Cancer Discovery74 citations Open access
Semantic Scholar
Increased pathologic upstaging with rising time to treatment initiation for head and neck cancer: A mechanism for increased mortality
R. Xiao, M. Ward, Kailin Yang, D. Adelstein +3 more
2018Cancer73 citations Open access
Semantic Scholar
Preoperative radiosurgery for resected brain metastases: the PROPS-BM multicenter cohort study.
R. Prabhu, R. Dhakal, Z. Vaslow, T. Dan +13 more
2021International Journal of Radiation Oncology, Biology, Physics72 citations
Semantic Scholar
Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells
Zhixin Qiu, Linjie Zhao, Jialing Shen, Zhengyu Liang +26 more
2021Cancer Discovery61 citations Open access
Semantic Scholar
RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation.
Qi Xie, Qiulian Wu, Leo J Y Kim, Tyler E. Miller +12 more
2016Journal of Clinical Investigation58 citations Open access
Semantic Scholar
CDC20 maintains tumor initiating cells
Qi Xie, Qiulian Wu, S. Mack, Kailin Yang +6 more
2015OncoTarget54 citations Open access
Semantic Scholar
Malignant Transformation of Molecularly Classified Adult Low Grade Glioma.
M. Tom, Deborah Y. Park, Kailin Yang, C. M. Leyrer +14 more
2019International Journal of Radiation Oncology, Biology, Physics53 citations
Semantic Scholar
Dual role of CXCL8 in maintaining the mesenchymal state of glioblastoma stem cells and M2-like tumor-associated macrophages.
Wei Yuan, Qian Zhang, Danling Gu, Chen-Fei Lu +39 more
2023Clinical Cancer Research42 citations Open access
Semantic Scholar
Michael Acceptor-Based Peptidomimetic Inhibitor of Main Protease from Porcine Epidemic Diarrhea Virus.
Fenghua Wang, Cheng Chen, Kailin Yang, Yang Xu +8 more
2017Journal of Medicinal Chemistry35 citations
Semantic Scholar
Crystal Structure of Feline Infectious Peritonitis Virus Main Protease in Complex with Synergetic Dual Inhibitors
Fenghua Wang, Cheng Chen, Xuemeng Liu, Kailin Yang +2 more
2015Journal of Virology31 citations Open access
Semantic Scholar
SREBP2 maintains glioblastoma stem cells through keeping the balance between cholesterol biosynthesis and uptake.
Danling Gu, Feng-Qi Zhou, Hao You, Jiancheng Gao +26 more
2023Neuro-Oncology29 citations Open access
Semantic Scholar
Radiomic Features Associated With HPV Status on Pretreatment Computed Tomography in Oropharyngeal Squamous Cell Carcinoma Inform Clinical Prognosis
Bo-Lin Song, Kailin Yang, Jonathan C. Garneau, Cheng Lu +10 more
2021Frontiers in Oncology29 citations Open access
Semantic Scholar
Structural insight into the Zika virus capsid encapsulating the viral genome
Ting Li, Qi Zhao, Xiao-Yun Yang, Cheng Chen +9 more
2018Cell Research29 citations Open access
Semantic Scholar
Risk Factors for Progression and Toxic Effects After Preoperative Stereotactic Radiosurgery for Patients With Resected Brain Metastases.
R. Prabhu, T. Akinyelu, Z. Vaslow, J. Matsui +16 more
2023JAMA Oncology28 citations Open access
Semantic Scholar
An Imaging Biomarker of Tumor-Infiltrating Lymphocytes to Risk-Stratify Patients With HPV-Associated Oropharyngeal Cancer
Germán Corredor, P. Toro, C. Koyuncu, Cheng Lu +18 more
2021Journal of the National Cancer Institute22 citations Open access
Semantic Scholar
Mechanism of ATP hydrolysis by the Zika virus helicase
Xiao-Yun Yang, Cheng Chen, H. Tian, H. Chi +8 more
2018The FASEB Journal21 citations Open access
Semantic Scholar
A delicate initiation: Lipolysis of lipid droplets fuels glioblastoma.
Kailin Yang, J. Rich
2021Molecules and Cells15 citations Open access
Semantic Scholar
Stereotactic Body Radiation Therapy for Sarcoma Pulmonary Metastases
W. Asha, S. Koro, Z. Mayo, Kailin Yang +9 more
2023American Journal of Clinical Oncology14 citations
Semantic Scholar
CT radiomic signature predicts survival and chemotherapy benefit in stage I and II HPV-associated oropharyngeal carcinoma
Bo-Lin Song, Kailin Yang, V. Viswanathan, Xiang-Xue Wang +7 more
2023npj Precision Oncology14 citations Open access
Semantic Scholar
Growth factor receptor signaling induces mitophagy through epitranscriptomic regulation
D. Lv, Kailin Yang, Jeremy N. Rich
2022Autophagy14 citations Open access
Semantic Scholar
Recursive partitioning analysis is predictive of overall survival for patients undergoing spine stereotactic radiosurgery
E. Balagamwala, Jacob A. Miller, Chandana A. Reddy, L. Angelov +9 more
2018Journal of Neuro-Oncology12 citations
Semantic Scholar
Machine Learning Driven Index of Tumor Multinucleation Correlates with Survival and Suppressed Anti-tumor Immunity in Head and Neck Squamous Cell Carcinoma Patients
C. Koyuncu, M. Frederick, Lester D. R. Thompson, Germán Corredor +14 more
2023Oral Oncology11 citations Open access
Semantic Scholar
Image Analysis Reveals Differences in Tumor Multinucleations in Black and White Oropharyngeal Squamous Cell Carcinoma Patients
C. Koyuncu, Reetoja Nag, Cheng Lu, Germán Corredor +23 more
2022Cancer11 citations Open access
Semantic Scholar
Immunometabolic rewiring in tumorigenesis and anti-tumor immunotherapy
Xin Lian, Kailin Yang, Ren-Liang Li, Mao-Mao Li +5 more
2022Molecular Cancer10 citations Open access
Semantic Scholar
Comparison of real‐world outcomes following immunotherapy in recurrent or metastatic head and neck squamous cell carcinoma with outcomes of randomized controlled trials
A. Yalamanchali, Kailin Yang, L. Roof, N. Lopetegui-Lia +7 more
2023Head and Neck7 citations Open access
Semantic Scholar
Proteomics mining of cancer hallmarks on a single-cell resolution.
Mao-Mao Li, Jing Zuo, Kailin Yang, Ping Wang +1 more
2023Mass spectrometry reviews (Print)5 citations
Semantic Scholar

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Qiulian Wu — researcher profile on SciRah
Xiu-Xing Wang×12
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