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D. Sonkin · SciRah

Researcher profile · Semantic Scholar

D. Sonkin

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D. Sonkin — researcher profile on SciRah

h-index: 23
Works: 85
Citations: 14K

Most-cited papers

The Cancer Cell Line Encyclopedia enables predictive modeling of anticancer drug sensitivity
J. Barretina, G. Caponigro, N. Stransky, K. Venkatesan +57 more
2012Nature7,580 citations Open access
Semantic Scholar
Next-generation characterization of the Cancer Cell Line Encyclopedia
Mahmoud Ghandi, Franklin W. Huang, Judit Jané-Valbuena, G. Kryukov +64 more
2019Nature2,943 citations Open access
Semantic Scholar
TP53 Variations in Human Cancers: New Lessons from the IARC TP53 Database and Genomics Data
L. Bouaoun, D. Sonkin, M. Ardin, M. Hollstein +3 more
2016Human Mutation700 citations
Semantic Scholar
Cancer treatments: past, present, and future
D. Sonkin, Anish Thomas, Beverly A. Teicher
2024Cancer Genetics566 citations Open access
Semantic Scholar
Consistency of drug profiles and predictors in large-scale cancer cell line data
N. Stransky, Mahmoud Ghandi, G. Kryukov, L. Garraway +24 more
2015Nature372 citations Open access
Semantic Scholar
Standards for the Classification of Pathogenicity of Somatic Variants in Cancer (Oncogenicity): Joint Recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC)
P. Horák, M. Griffith, Arpad M. Danos, B. Pitel +43 more
2022Genetics in Medicine231 citations Open access
Semantic Scholar
Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
J. Barretina, G. Caponigro, N. Stransky, K. Venkatesan +57 more
2012Nature175 citations
Semantic Scholar
Small Cell Lung Cancer Screen of Oncology Drugs, Investigational Agents, and Gene and microRNA Expression.
E. Polley, M. Kunkel, David Evans, T. Silvers +14 more
2016Journal of the National Cancer Institute158 citations Open access
Semantic Scholar
A harmonized meta-knowledgebase of clinical interpretations of somatic genomic variants in cancer
A. Wagner, B. Walsh, Georgia Mayfield, D. Tamborero +35 more
2020Nature Genetics142 citations Open access
Semantic Scholar
Integrative radiogenomic profiling of squamous cell lung cancer
M. Abazeed, Drew J. Adams, Kristen E. Hurov, P. Tamayo +11 more
2013Cancer Research120 citations Open access
Semantic Scholar
Epigenome-wide DNA methylation analysis of small cell lung cancer cell lines suggests potential chemotherapy targets
J. Krushkal, T. Silvers, W. Reinhold, D. Sonkin +9 more
2020Clinical Epigenetics64 citations Open access
Semantic Scholar
Somatic cancer variant curation and harmonization through consensus minimum variant level data
D. Ritter, S. Roychowdhury, A. Roy, Shruti Rao +14 more
2016Genome Medicine61 citations Open access
Semantic Scholar
The NCI Transcriptional Pharmacodynamics Workbench: a tool to examine dynamic expression profiling of therapeutic response in the NCI-60 cell line panel
A. Monks, Yingdong Zhao, C. Hose, Hossein A. Hamed +18 more
2018Cancer Research56 citations Open access
Semantic Scholar
Integrating Somatic Variant Data and Biomarkers for Germline Variant Classification in Cancer Predisposition Genes
M. Walsh, D. Ritter, C. Kesserwan, D. Sonkin +15 more
2018Human Mutation56 citations Open access
Semantic Scholar
Genetic Mechanisms in Apc-Mediated Mammary Tumorigenesis
M. Kuraguchi, N. Ohene-Baah, D. Sonkin, R. Bronson +1 more
2009PLoS Genetics51 citations Open access
Semantic Scholar
Inhibiting Tankyrases sensitizes KRAS-mutant cancer cells to MEK inhibitors via FGFR2 feedback signaling.
M. Schoumacher, Kristen E. Hurov, J. Lehar, Y. Yan-Neale +13 more
2014Cancer Research42 citations
Semantic Scholar
Tumor Suppressors Status in Cancer Cell Line Encyclopedia
D. Sonkin, Mehedi Hassan, D. Murphy, T. Tatarinova
2013Molecular Oncology31 citations Open access
Semantic Scholar
Are neuroendocrine negative small cell lung cancer and large cell neuroendocrine carcinoma with WT RB1 two faces of the same entity?
D. Sonkin, Anish Thomas, B. Teicher
2019Lung Cancer Management26 citations Open access
Semantic Scholar
Standard operating procedure for curation and clinical interpretation of variants in cancer
Arpad M. Danos, K. Krysiak, Erica K. Barnell, Adam C. Coffman +19 more
2019Genome Medicine25 citations Open access
Semantic Scholar
A harmonized meta-knowledgebase of clinical interpretations of cancer genomic variants
A. Wagner, B. Walsh, Georgia Mayfield, D. Tamborero +33 more
2018bioRxiv24 citations Open access
Semantic Scholar
Integrative modeling of multi-omics data to identify cancer drivers and infer patient-specific gene activity
A. Pavel, D. Sonkin, Anupama Reddy
2016BMC Systems Biology24 citations Open access
Semantic Scholar
Loss of Rb1 in the gastrointestinal tract of Apc1638N mice promotes tumors of the cecum and proximal colon
M. Kucherlapati, Kan Yang, K. Fan, M. Kuraguchi +6 more
2008Proceedings of the National Academy of Sciences of the United States of America24 citations Open access
Semantic Scholar
Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC).
P. Horák, M. Griffith, Arpad M. Danos, B. Pitel +43 more
2022Genetics in Medicine23 citations Open access
Semantic Scholar
Small cell lung carcinoma cell line screen of etoposide/carboplatin plus a third agent
B. Teicher, T. Silvers, M. Selby, R. Delosh +9 more
2017Cancer Medicine22 citations Open access
Semantic Scholar
ClinGen Cancer Somatic Working Group – standardizing and democratizing access to cancer molecular diagnostic data to drive translational research
S. Madhavan, D. Ritter, C. Micheel, Shruti Rao +7 more
2017bioRxiv20 citations Open access
Semantic Scholar
MutSpliceDB: A database of splice sites variants with RNA-seq based evidence on effects on splicing
Alida Palmisano, S. Vural, Ying-Dong Zhao, D. Sonkin
2021Human Mutation19 citations Open access
Semantic Scholar
Expression signature based on TP53 target genes doesn't predict response to TP53-MDM2 inhibitor in wild type TP53 tumors
D. Sonkin
2015eLife19 citations Open access
Semantic Scholar
Adapting crowdsourced clinical cancer curation in CIViC to the ClinGen minimum variant level data community‐driven standards
Arpad M. Danos, D. Ritter, A. Wagner, K. Krysiak +16 more
2018Human Mutation17 citations Open access
Semantic Scholar
Targeted Investigational Oncology Agents in the NCI-60: A Phenotypic Systems–based Resource
Joel Morris, M. Kunkel, Stephen L White, D. Wishka +17 more
2023Molecular Cancer Therapeutics16 citations Open access
Semantic Scholar
Neuroendocrine negative SCLC is mostly RB1 WT and may be sensitive to CDK4/6 inhibition
D. Sonkin, S. Vural, Anish Thomas, B. Teicher
2019bioRxiv12 citations Open access
Semantic Scholar
Improving transparency of computational tools for variant effect prediction
R. Karchin, P. Radivojac, A. O'Donnell-Luria, M. Greenblatt +2 more
2024Nature Genetics10 citations
Semantic Scholar
The identification and characterization of a STAT5 gene signature in hematologic malignancies
D. Sonkin, Michael R. Palmer, Xian-Hui Rong, K. Horrigan +10 more
2015Cancer Biomarkers10 citations Open access
Semantic Scholar
Detection of homozygous deletions in tumor‐suppressor genes ranging from dozen to hundreds nucleotides in cancer models
L. Chang, S. Vural, D. Sonkin
2017Human Mutation9 citations Open access
Semantic Scholar
Prediction of drug response using genomic signatures from the Cancer Cell Line Encyclopedia
K. Venkatesan, N. Stransky, A. Margolin, Anupama Reddy +12 more
20108 citations
Semantic Scholar
Bioinformatics Tools and Resources for Cancer Immunotherapy Study.
Alida Palmisano, J. Krushkal, Ming-Chung Li, Jianwen Fang +5 more
2019Methods in molecular biology7 citations
Semantic Scholar
Abstract 5455: Integrative analysis of the Cancer Cell Line Encyclopedia reveals genetic and transcriptional predictors of compound sensitivity
J. Barretina, N. Stransky, G. Caponigro, Sungjoon Kim +46 more
20115 citations
Semantic Scholar
Interpreting the functional impact of genetic variants: the need for context qualifiers
Simone Martinelli, Hélène Cavé, A. De Luca, M. DiStefano +9 more
2025American Journal of Human Genetics4 citations Open access
Semantic Scholar
TP53 variations in human cancers: new lessons from the IARC TP53 Database and genomic studies
M. Olivier, L. Bouaoun, D. Sonkin, M. Ardin +3 more
20164 citations
Semantic Scholar
Abstract 4884: Targeted investigational oncology agents (IOA) in the NCI60: a phenotypic systems-based resource
Joel Morris, M. Kunkel, Stephen L White, D. Wishka +13 more
2023Cancer Research2 citations
Semantic Scholar
TP53 isoform junction reads based analysis in malignant and normal contexts
S. Vural, L. Chang, Laura M. Yee, D. Sonkin
2021Scientific Reports1 citations Open access
Semantic Scholar
The CIViC knowledge model and standard operating procedures for curation and clinical interpretation of variants in cancer
Arpad M. Danos, K. Krysiak, Erica K. Barnell, Adam C. Coffman +17 more
2019bioRxiv1 citations Open access
Semantic Scholar
Integrative radiogenomic profiling of squamous cell lung cancer
M. Abazeed, Drew J. Adams, Kristen E. Hurov, Pablo Tamayo +12 more
20131 citations
Semantic Scholar
Identification of pSTAT5 gene signature in hematologic malignancy.
D. Sonkin, C. Regnier, Xian-Hui Rong, C. Fanton +8 more
20131 citations
Semantic Scholar
Abstract 105: Integrative analysis of genomic and pharmacologic data from the Cancer Cell Line Encyclopedia
N. Stransky, Kavitha Venkhatesan, Michael P. Morrissey, J. Barretina +34 more
2010Cellular and Molecular Biology1 citations
Semantic Scholar
80. Integrating expert knowledge for somatic variant interpretation: Achievements and future directions of ClinGen somatic
J. Saliba, Arpad M. Danos, K. Krysiak, Adam C. Coffman +24 more
2025Cancer Genetics0 citations Open access
Semantic Scholar
68. ClinGen Cancer Variant Interpretation (CVI): Updates and recommendations on the ClinGen/CGC/VICC Oncogenicity SOP
Deborah Ritter, D. Sonkin, M. Griffith, O. Griffith +10 more
2024Cancer Genetics0 citations
Semantic Scholar
54. Creation of a knowledgebase of high-quality assertions of the clinical actionability of somatic variants in cancer
J. Saliba, Arpad M. Danos, K. Krysiak, Adam C. Coffman +24 more
2024Cancer Genetics0 citations
Semantic Scholar
94. Initial efforts of the ClinGen Solid Tumor Taskforce in promoting variant curation in solid tumors into CIViC
L. Satgunaseelan, M. Sukhanova, G. Toruner, Arpad M. Danos +23 more
2023Cancer Genetics0 citations
Semantic Scholar
16. ClinGen Cancer Variant Interpretation (CVI) Committee: Pilot guidance for somatic cancer variant curation expert panels
D. Ritter, Eric J. Duncavage, J. Elvin, G. Frampton +24 more
2023Cancer Genetics0 citations
Semantic Scholar
Abstract 1192: The Clinical Genome Resource (ClinGen) somatic cancer clinical domain working group
J. Saliba, G. Raca, A. Roy, I. King +25 more
2022Cancer Research0 citations
Semantic Scholar

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