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R. van Eijk · SciRah

Researcher profile · Semantic Scholar

R. van Eijk

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R. van Eijk — researcher profile on SciRah

h-index: 40
Works: 131
Citations: 7,975

Most-cited papers

Somatic mosaic IDH1 or IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome
T. Pansuriya, R. van Eijk, Pio d' Adamo, M. van Ruler +23 more
2011Nature Genetics535 citations Open access
Semantic Scholar
E-cadherin transcriptional downregulation by promoter methylation but not mutation is related to epithelial-to-mesenchymal transition in breast cancer cell lines
M. Lombaerts, T. van Wezel, K. Philippo, J. Dierssen +7 more
2006British Journal of Cancer362 citations Open access
Semantic Scholar
A genome-wide association study of Hodgkin Lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21, and 10p14 (GATA3)
V. Enciso-Mora, P. Broderick, Yussanne P. Ma, R. Jarrett +41 more
2010Nature Genetics206 citations Open access
Semantic Scholar
Rapid KRAS, EGFR, BRAF and PIK3CA Mutation Analysis of Fine Needle Aspirates from Non-Small-Cell Lung Cancer Using Allele-Specific qPCR
R. van Eijk, Jappe Licht, Melanie Schrumpf, Mehrdad Talebian Yazdi +9 more
2011PLoS ONE192 citations Open access
Semantic Scholar
Expression of HLA class I antigen, aspirin use, and survival after a diagnosis of colon cancer.
M. Reimers, E. Bastiaannet, R. Langley, R. van Eijk +9 more
2014JAMA Internal Medicine104 citations Open access
Semantic Scholar
Differential gene expression in ovarian tumors reveals Dusp 4 and Serpina 5 as key regulators for benign behavior of serous borderline tumors.
Nathalie L. G. Sieben, J. Oosting, A. Flanagan, J. Prat +6 more
2005Journal of Clinical Oncology101 citations
Semantic Scholar
Chromosome 8q23.3 and 11q23.1 variants modify colorectal cancer risk in Lynch syndrome.
J. Wijnen, R. Brohet, R. van Eijk, S. Jagmohan-Changur +21 more
2009Gastroenterology94 citations
Semantic Scholar
Statin Use After Diagnosis of Colon Cancer and Patient Survival.
P. Voorneveld, M. Reimers, E. Bastiaannet, R. Jacobs +11 more
2017Gastroenterology92 citations Open access
Semantic Scholar
Reliable high-throughput genotyping and loss-of-heterozygosity detection in formalin-fixed, paraffin-embedded tumors using single nucleotide polymorphism arrays.
E. Lips, J. Dierssen, R. van Eijk, J. Oosting +7 more
2005Cancer Research92 citations Open access
Semantic Scholar
High prevalence of MYD88 and CD79B mutations in intravascular large B-cell lymphoma.
A. Schrader, P. Jansen, R. Willemze, M. Vermeer +17 more
2018Blood88 citations Open access
Semantic Scholar
Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational enrichment in kinases associated with cell migration and invasion.
Willie Yu, J. Mcpherson, M. Stevenson, R. van Eijk +14 more
2015Journal of Clinical Endocrinology and Metabolism86 citations Open access
Semantic Scholar
Genome Haploidisation with Chromosome 7 Retention in Oncocytic Follicular Thyroid Carcinoma
W. Corver, D. Ruano, Karin Weijers, Wietske C. E. den Hartog +11 more
2012PLoS ONE86 citations Open access
Semantic Scholar
No genomic aberrations in Langerhans cell histiocytosis as assessed by diverse molecular technologies
Cristiana E. T. da Costa, K. Szuhai, R. van Eijk, M. Hoogeboom +8 more
2009Genes, Chromosomes and Cancer84 citations
Semantic Scholar
Chromium speciation in coal and biomass co-combustion products.
A. Stam, R. Meij, Henk Te Winkel, R. van Eijk +2 more
2011Environmental Science and Technology80 citations
Semantic Scholar
Cell Cycle/Apoptosis Molecule Expression Correlates with Imatinib Response in Patients with Advanced Gastrointestinal Stromal Tumors
S. Romeo, M. Debiec-Rychter, M. Van Glabbeke, Heidi van Paassen +9 more
2009Clinical Cancer Research75 citations Open access
Semantic Scholar
Assessment of a fully automated high-throughput DNA extraction method from formalin-fixed, paraffin-embedded tissue for KRAS, and BRAF somatic mutation analysis.
R. van Eijk, L. Stevens, H. Morreau, T. van Wezel
2013Experimental and molecular pathology (Print)73 citations Open access
Semantic Scholar
Enrichment of Low Penetrance Susceptibility Loci in a Dutch Familial Colorectal Cancer Cohort
Anneke Middeldorp, S. Jagmohan-Changur, R. van Eijk, C. Tops +9 more
2009Cancer Epidemiology, Biomarkers and Prevention73 citations Open access
Semantic Scholar
High-resolution copy number analysis of paraffin-embedded archival tissue using SNP BeadArrays.
J. Oosting, E. Lips, R. van Eijk, P. Eilers +4 more
2007Genome Research71 citations Open access
Semantic Scholar
Improved risk assessment of endometrial cancer by combined analysis of MSI, PI3K-AKT, Wnt/β-catenin and P53 pathway activation.
R. Nout, T. Bosse, C. Creutzberg, I. Jürgenliemk-Schulz +6 more
2012Gynecologic Oncology67 citations
Semantic Scholar
Colorectal carcinomas in MUTYH-associated polyposis display histopathological similarities to microsatellite unstable carcinomas
M. Nielsen, N. D. de Miranda, M. van Puijenbroek, E. Jordanova +7 more
2009BMC Cancer67 citations Open access
Semantic Scholar
Early onset MSI-H colon cancer with MLH1 promoter methylation, is there a genetic predisposition?
E. V. van Roon, M. van Puijenbroek, Anneke Middeldorp, R. van Eijk +10 more
2010BMC Cancer62 citations Open access
Semantic Scholar
PIK3CA kinase domain mutation identifies a subgroup of stage III colon cancer patients with poor prognosis
A. F. Sarasqueta, E. Zeestraten, T. van Wezel, G. van Lijnschoten +9 more
2011Cellular Oncology53 citations Open access
Semantic Scholar
Macrodissection versus microdissection of rectal carcinoma: minor influence of stroma cells to tumor cell gene expression profiles
E. de Bruin, S. van de Pas, E. Lips, R. van Eijk +9 more
2005BMC Genomics49 citations Open access
Semantic Scholar
Progression and Tumor Heterogeneity Analysis in Early Rectal Cancer
E. Lips, R. van Eijk, E. D. de Graaf, P. Doornebosch +7 more
2008Clinical Cancer Research48 citations Open access
Semantic Scholar
High frequency of copy‐neutral LOH in MUTYH‐associated polyposis carcinomas
Anneke Middeldorp, M. van Puijenbroek, M. Nielsen, W. Corver +11 more
2008Journal of Pathology48 citations
Semantic Scholar
Molecular Background of Colorectal Tumors From Patients With Lynch Syndrome Associated With Germline Variants in PMS2.
S. T. ten Broeke, Tom C. van Bavel, A. M. Jansen, E. Gomez-Garcia +12 more
2018Gastroenterology47 citations Open access
Semantic Scholar
Beneficial Effects of the mTOR Inhibitor Everolimus in Patients with Advanced Medullary Thyroid Carcinoma: Subgroup Results of a Phase II Trial
T. Schneider, D. de Wit, T. Links, N. V. van Erp +7 more
2015International Journal of Endocrinology47 citations Open access
Semantic Scholar
Integral analysis of p53 and its value as prognostic factor in sporadic colon cancer
A. Farina Sarasqueta, G. Forte, W. Corver, N. D. de Miranda +6 more
2013BMC Cancer47 citations Open access
Semantic Scholar
Integrating chromosomal aberrations and gene expression profiles to dissect rectal tumorigenesis
E. Lips, R. van Eijk, E. D. de Graaf, J. Oosting +7 more
2008BMC Cancer45 citations Open access
Semantic Scholar
Single nucleotide polymorphism array analysis of chromosomal instability patterns discriminates rectal adenomas from carcinomas
E. Lips, E. D. de Graaf, R. Tollenaar, R. van Eijk +9 more
2007Journal of Pathology45 citations
Semantic Scholar
Designing a High-Throughput Somatic Mutation Profiling Panel Specifically for Gynaecological Cancers
Vivian M. Spaans, Marjolijn D. Trietsch, S. Crobach, E. Stelloo +10 more
2014PLoS ONE43 citations Open access
Semantic Scholar
Sensitive and specific KRAS somatic mutation analysis on whole-genome amplified DNA from archival tissues.
R. van Eijk, M. van Puijenbroek, Amiet R. Chhatta, N. Gupta +5 more
2010Journal of Molecular Diagnostics39 citations Open access
Semantic Scholar
Genome-wide allelic state analysis on flow-sorted tumor fractions provides an accurate measure of chromosomal aberrations.
W. Corver, Anneke Middeldorp, N. T. ter Haar, E. Jordanova +7 more
2008Cancer Research37 citations Open access
Semantic Scholar
Near‐haploidization significantly associates with oncocytic adrenocortical, thyroid, and parathyroid tumors but not with mitochondrial DNA mutations
W. Corver, T. van Wezel, Kees Molenaar, Melanie Schrumpf +5 more
2014Genes, Chromosomes and Cancer35 citations
Semantic Scholar
Incidence and determinants of thrombotic and bleeding complications in patients with glioblastoma
F. Kaptein, M. A. Stals, M. Kapteijn, S. Cannegieter +10 more
2022Journal of Thrombosis and Haemostasis30 citations Open access
Semantic Scholar
Frequent mutated B2M, EZH2, IRF8, and TNFRSF14 in primary bone diffuse large B-cell lymphoma reflect a GCB phenotype.
Ruben Al de Groen, R. van Eijk, Stefan Böhringer, T. van Wezel +26 more
2021Blood Advances29 citations Open access
Semantic Scholar
Increased frequency of 20q gain and copy‐neutral loss of heterozygosity in mismatch repair proficient familial colorectal carcinomas
Anneke Middeldorp, R. van Eijk, J. Oosting, G. Forte +8 more
2012International Journal of Cancer29 citations Open access
Semantic Scholar
Genome-wide copy neutral LOH is infrequent in familial and sporadic microsatellite unstable carcinomas
M. van Puijenbroek, Anneke Middeldorp, C. Tops, R. van Eijk +7 more
2008Familial Cancer28 citations
Semantic Scholar
Validation and Implementation of BRCA1/2 Variant Screening in Ovarian Tumor Tissue.
M. D. de Jonge, D. Ruano, R. van Eijk, N. van der Stoep +13 more
2018Journal of Molecular Diagnostics26 citations Open access
Semantic Scholar
The Influence of BRAF and KRAS Mutation Status on the Association between Aspirin Use and Survival after Colon Cancer Diagnosis
M. Frouws, M. Reimers, Marloes Swets, E. Bastiaannet +9 more
2017PLoS ONE25 citations Open access
Semantic Scholar
Diagnostic and prognostic significance of CDKN2A/CDKN2B deletions in patients with transformed mycosis fungoides and primary cutaneous CD30‐positive lymphoproliferative disease
A. Nicolae-Cristea, M. F. Benner, W. Zoutman, R. van Eijk +3 more
2015British Journal of Dermatology24 citations
Semantic Scholar
ATBF1 and NQO1 as candidate targets for allelic loss at chromosome arm 16q in breast cancer: Absence of somatic ATBF1 mutations and no role for the C609T NQO1 polymorphism
A. Cleton-Jansen, R. van Eijk, M. Lombaerts, M. Schmidt +7 more
2008BMC Cancer22 citations Open access
Semantic Scholar
Somatic mutation profiles in primary colorectal cancers and matching ovarian metastases: Identification of driver and passenger mutations
S. Crobach, D. Ruano, R. van Eijk, Melanie Schrumpf +3 more
2016The Journal of Pathology: Clinical Research20 citations Open access
Semantic Scholar
Cell-of-origin classification using the Hans and Lymph2Cx algorithms in primary cutaneous large B-cell lymphomas
A. Schrader, R. D. de Groen, R. Willemze, P. Jansen +12 more
2022Virchows Archiv17 citations Open access
Semantic Scholar
The complexity of screening PMS2 in DNA isolated from formalin-fixed paraffin-embedded material
A. M. Jansen, C. Tops, D. Ruano, R. van Eijk +6 more
2019European Journal of Human Genetics17 citations Open access
Semantic Scholar
Mutational analyses of epidermal growth factor receptor and downstream pathways in adrenocortical carcinoma.
I. Hermsen, H. Haak, R. D. de Krijger, T. Kerkhofs +9 more
2013European Journal of Endocrinology17 citations
Semantic Scholar
Genetic Stability of Driver Alterations in Primary Cutaneous Diffuse Large B-Cell Lymphoma, Leg Type and Their Relapses: A Rationale for the Use of Molecular-Based Methods for More Effective Disease Monitoring
A. Schrader, R. D. de Groen, R. Willemze, P. Jansen +14 more
2022Cancers16 citations Open access
Semantic Scholar
Real-world routine diagnostic molecular analysis for TP53 mutational status is recommended over p53 immunohistochemistry in B-cell lymphomas
L. D. de Haan, R. D. de Groen, F. D. de Groot, T. Noordenbos +15 more
2023Virchows Archiv15 citations Open access
Semantic Scholar
MLPAinter for MLPA interpretation: an integrated approach for the analysis, visualisation and data management of Multiplex Ligation-dependent Probe Amplification
R. van Eijk, P. Eilers, R. Natté, A. Cleton-Jansen +3 more
2010BMC Bioinformatics15 citations Open access
Semantic Scholar
Target-enriched next-generation sequencing reveals differences between primary and secondary ovarian tumors in formalin-fixed, paraffin-embedded tissue.
S. Crobach, D. Ruano, R. van Eijk, G. Fleuren +5 more
2015Journal of Molecular Diagnostics14 citations Open access
Semantic Scholar

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T. van Wezel×42
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H. Morreau×31
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J. Oosting×18
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Anneke Middeldorp

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Anneke Middeldorp — researcher profile on SciRah

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F. Hes — researcher profile on SciRah

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E. Lips — researcher profile on SciRah

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C. V. D. van de Velde — researcher profile on SciRah

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N. D. de Miranda — researcher profile on SciRah

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M. van Puijenbroek — researcher profile on SciRah