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R. Nout · SciRah

Researcher profile · Semantic Scholar

R. Nout

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R. Nout — researcher profile on SciRah

h-index: 58
Works: 251
Citations: 15K

Most-cited papers

Molecular Classification of the PORTEC-3 Trial for High-Risk Endometrial Cancer: Impact on Prognosis and Benefit From Adjuvant Therapy
A. Léon-Castillo, S. D. de Boer, M. Powell, L. Mileshkin +18 more
2020Journal of Clinical Oncology693 citations Open access
Semantic Scholar
MRI-guided adaptive brachytherapy in locally advanced cervical cancer (EMBRACE-I): a multicentre prospective cohort study.
R. Pötter, K. Tanderup, M. Schmid, I. Jürgenliemk-Schulz +22 more
2021The Lancet Oncology559 citations Open access
Semantic Scholar
Prognostic refinement of NSMP high-risk endometrial cancers using oestrogen receptor immunohistochemistry
L. Vermij, J. Jobsen, A. Léon-Castillo, M. Brinkhuis +17 more
2022British Journal of Cancer182 citations Open access
Semantic Scholar
p53 immunohistochemistry in endometrial cancer: clinical and molecular correlates in the PORTEC-3 trial
L. Vermij, A. Léon-Castillo, Naveena Singh, M. Powell +33 more
2022Modern Pathology165 citations Open access
Semantic Scholar
Tertiary lymphoid structures critical for prognosis in endometrial cancer patients
N. Horeweg, H. Workel, Dominik Loiero, D. Church +17 more
2022Nature Communications131 citations Open access
Semantic Scholar
Interpretable deep learning model to predict the molecular classification of endometrial cancer from haematoxylin and eosin-stained whole-slide images: a combined analysis of the PORTEC randomised trials and clinical cohorts.
Sarah Fremond, S. Andani, J. Barkey Wolf, J. Dijkstra +20 more
2022The Lancet Digital Health129 citations Open access
Semantic Scholar
Prediction of recurrence risk in endometrial cancer with multimodal deep learning
S. Volinsky-Fremond, N. Horeweg, S. Andani, J. Barkey Wolf +21 more
2024Nature Medicine104 citations Open access
Semantic Scholar
Prognostic relevance of the molecular classification in high-grade endometrial cancer for patients staged by lymphadenectomy and without adjuvant treatment.
A. Léon-Castillo, N. Horeweg, E. Peters, T. Rutten +10 more
2022Gynecologic Oncology102 citations Open access
Semantic Scholar
Prevalence and Prognosis of Lynch Syndrome and Sporadic Mismatch Repair Deficiency in Endometrial Cancer
C. Post, E. Stelloo, V. Smit, D. Ruano +19 more
2021Journal of the National Cancer Institute91 citations Open access
Semantic Scholar
Molecular Classification Predicts Response to Radiotherapy in the Randomized PORTEC-1 and PORTEC-2 Trials for Early-Stage Endometrioid Endometrial Cancer
N. Horeweg, R. Nout, I. Jürgenliemk-Schulz, L. Lutgens +12 more
2023Journal of Clinical Oncology85 citations Open access
Semantic Scholar
Defining Substantial Lymphovascular Space Invasion in Endometrial Cancer
E. Peters, A. Léon-Castillo, V. Smit, M. Boennelycke +11 more
2021International Journal of Gynecological Pathology80 citations Open access
Semantic Scholar
Risk Factors for Local Failure Following Chemoradiation and Magnetic Resonance Image–Guided Brachytherapy in Locally Advanced Cervical Cancer: Results From the EMBRACE-I Study
M. Schmid, J. Lindegaard, U. Mahantshetty, K. Tanderup +26 more
2023Journal of Clinical Oncology78 citations Open access
Semantic Scholar
Adjuvant chemoradiotherapy versus radiotherapy alone in women with high-risk endometrial cancer (PORTEC-3): 10-year clinical outcomes and post-hoc analysis by molecular classification from a randomised phase 3 trial
C. Post, S. D. de Boer, M. Powell, Linda Mileshkin +25 more
2025The Lancet Oncology47 citations Open access
Semantic Scholar
Risk factors and dose-effects for bladder fistula, bleeding and cystitis after radiotherapy with imaged-guided adaptive brachytherapy for cervical cancer: An EMBRACE analysis.
S. Spampinato, L. Fokdal, R. Pötter, C. Haie-meder +20 more
2021Radiotherapy and Oncology46 citations Open access
Semantic Scholar
Impact of vaginal symptoms and hormonal replacement therapy on sexual outcomes in locally advanced cervical cancer patients after definitive chemoradiotherapy - results from the EMBRACE-I study.
K. Kirchheiner, S. Smet, I. Jürgenliemk-Schulz, C. Haie-meder +21 more
2021International Journal of Radiation Oncology, Biology, Physics43 citations Open access
Semantic Scholar
Dose-Volume Effects and Risk Factors for Late Diarrhea in Cervix Cancer Patients after Radiochemotherapy with Image-Guided Adaptive Brachytherapy in the EMBRACE I Study.
Nina Boje Kibsgaard Jensen, R. Pötter, S. Spampinato, L. Fokdal +20 more
2020International Journal of Radiation Oncology, Biology, Physics43 citations Open access
Semantic Scholar
Substantial Lymphovascular Space Invasion Is an Adverse Prognostic Factor in High-Risk Endometrial Cancer
E. Peters, A. Léon-Castillo, E. Høgdall, M. Boennelycke +6 more
2021International Journal of Gynecological Pathology37 citations Open access
Semantic Scholar
Overall severe morbidity after chemo-radiotherapy and MRI guided adaptive brachytherapy in locally advanced cervical cancer: results from the EMBRACE-I study.
A. Vittrup, K. Kirchheiner, R. Pötter, L. Fokdal +21 more
2023International Journal of Radiation Oncology, Biology, Physics35 citations Open access
Semantic Scholar
Prognostic impact and causality of age on oncological outcomes in women with endometrial cancer: a multimethod analysis of the randomised PORTEC-1, PORTEC-2, and PORTEC-3 trials.
F. C. Wakkerman, Ji-Qing Wu, H. Putter, I. Jürgenliemk-Schulz +21 more
2024The Lancet Oncology34 citations Open access
Semantic Scholar
Phantom-based quality assurance for multicenter quantitative MRI in locally advanced cervical cancer.
P. van Houdt, J. Kallehauge, K. Tanderup, R. Nout +13 more
2020Radiotherapy and Oncology31 citations Open access
Semantic Scholar
GEC-ESTRO (ACROP) - ABS - CBG Consensus Brachytherapy Target Definition Guidelines for Recurrent Endometrial and Cervical Tumors in the Vagina.
M. Kamrava, E. Leung, F. Bachand, S. Beriwal +15 more
2022International Journal of Radiation Oncology, Biology, Physics30 citations Open access
Semantic Scholar
Severity and persistency of late gastrointestinal morbidity in locally advanced cervical cancer: lessons learned from EMBRACE-I and implications for the future.
S. Spampinato, N. Jensen, R. Pötter, L. Fokdal +26 more
2021International Journal of Radiation Oncology, Biology, Physics29 citations Open access
Semantic Scholar
Detection of Subclinical Cardiovascular Disease by Cardiovascular Magnetic Resonance in Lymphoma Survivors
N. van der Velde, C. Janus, Daniel J. Bowen, H. Hassing +6 more
2021JACC CardioOncology29 citations Open access
Semantic Scholar
Dose-effect relationship between vaginal dose points and vaginal stenosis in cervical cancer: an EMBRACE-I sub-study.
H. Westerveld, K. Kirchheiner, R. Nout, K. Tanderup +11 more
2022Radiotherapy and Oncology28 citations Open access
Semantic Scholar
Phase II study of definitive chemoradiation for locally advanced squamous cell cancer of the vulva: An efficacy study.
B. van Triest, M. Rasing, J. van der Velden, J. D. de Hullu +10 more
2021Gynecologic Oncology28 citations Open access
Semantic Scholar
Implementing an online radiotherapy quality assurance programme with supporting continuous medical education - report from the EMBRACE-II evaluation of cervix cancer IMRT contouring.
S. Duke, L. Tan, N. Jensen, T. Rumpold +7 more
2020Radiotherapy and Oncology28 citations
Semantic Scholar
Importance of the ICRU Bladder point dose on incidence and persistence of urinary frequency and incontinence in locally advanced cervical cancer: an EMBRACE analysis.
S. Spampinato, L. Fokdal, R. Pötter, C. Haie-meder +20 more
2020Radiotherapy and Oncology26 citations Open access
Semantic Scholar
Association of persistent morbidity after radiotherapy with quality of life in locally advanced cervical cancer survivors.
S. Spampinato, K. Tanderup, J. Lindegaard, M. Schmid +23 more
2023Radiotherapy and Oncology24 citations Open access
Semantic Scholar
Brachytherapy quality assurance in the PORTEC-4a trial for molecular-integrated risk profile guided adjuvant treatment of endometrial cancer.
B. Wortman, E. Astreinidou, M. Laman, E. M. van der Steen-Banasik +19 more
2020Radiotherapy and Oncology22 citations Open access
Semantic Scholar
Automated causal inference in application to randomized controlled clinical trials
Ji Wu, N. Horeweg, M. de Bruyn, R. Nout +9 more
2022Nature Machine Intelligence21 citations Open access
Semantic Scholar
Risk factors for nodal failure after radiochemotherapy and image-guided brachytherapy in locally advanced cervical cancer: an EMBRACE analysis.
M. Peters, A. De Leeuw, C. Nomden, K. Tanderup +23 more
2021Radiotherapy and Oncology21 citations Open access
Semantic Scholar
Prognostic implications of uterine cervical cancer regression during chemoradiation evaluated by the T-score in the multicenter XXX study.
J. Lindegaard, P. Petric, M. Schmid, N. Nesvacil +23 more
2022International Journal of Radiation Oncology, Biology, Physics19 citations Open access
Semantic Scholar
Persistence of late substantial patient-reported symptoms (LAPERS) after radiochemotherapy including image-guided adaptive brachytherapy for locally advanced cervical cancer: A report from the EMBRACE study.
A. Vittrup, K. Tanderup, S. Bentzen, N. Jensen +24 more
2020International Journal of Radiation Oncology, Biology, Physics19 citations Open access
Semantic Scholar
Association between the regular use of vaginal dilators and/or sexual activity and vaginal morbidity in locally advanced cervical cancer survivors - An EMBRACE-I study report.
K. Kirchheiner, A. Zaharie, S. Smet, S. Spampinato +16 more
2024International Journal of Radiation Oncology, Biology, Physics18 citations Open access
Semantic Scholar
Vaginal changes, sexual functioning and distress of women with locally advanced cervical cancer treated in the EMBRACE vaginal morbidity substudy.
I. Suvaal, K. Kirchheiner, R. Nout, A. Sturdza +9 more
2023Gynecologic Oncology18 citations Open access
Semantic Scholar
Radiotherapy Techniques and Treatment-Related Toxicity in the PORTEC-3 Trial: Comparison of Three-Dimensional Conformal Radiotherapy versus Intensity-Modulated Radiotherapy.
B. Wortman, C. Post, M. Powell, P. Khaw +20 more
2021International Journal of Radiation Oncology, Biology, Physics17 citations Open access
Semantic Scholar
Molecular and Clinicopathologic Characterization of Mismatch Repair-Deficient Endometrial Carcinoma Not Related to MLH1 Promoter Hypermethylation.
Merve Kaya, C. Post, C. Tops, M. Nielsen +17 more
2024Modern Pathology15 citations Open access
Semantic Scholar
Image-Guided Adaptive Brachytherapy (IGABT) for Primary Vaginal Cancer: Results of the International Multicenter RetroEMBRAVE Cohort Study
H. Westerveld, M. Schmid, R. Nout, C. Chargari +8 more
2021Cancers15 citations Open access
Semantic Scholar
Efficacy of a nurse-led sexual rehabilitation intervention for women with gynaecological cancers receiving radiotherapy: results of a randomised trial
I. Suvaal, Susanna B. Hummel, J. Mens, Charlotte C. Tuijnman-Raasveld +16 more
2024British Journal of Cancer13 citations Open access
Semantic Scholar
Biomarker expression and impact on clinical outcomes in an international study of chemoradiation and MRI-based image-guided brachytherapy for locally advanced cervical cancer: BIOEMBRACE.
S. Chopra, T. Bosse, N. Horeweg, K. Deodhar +18 more
2024International Journal of Radiation Oncology, Biology, Physics12 citations Open access
Semantic Scholar
Vaginal brachytherapy management of stage I and II endometrial cancer
A. S. V. D. van den Heerik, N. Horeweg, C. Creutzberg, R. Nout
2022International Journal of Gynecological Cancer11 citations Open access
Semantic Scholar
Risk factors for late persistent fatigue after chemoradiotherapy in locally advanced cervical cancer: an analysis from the EMBRACE-I study.
S. Smet, S. Spampinato, R. Pötter, I. Jürgenliemk-Schulz +19 more
2021International Journal of Radiation Oncology, Biology, Physics11 citations Open access
Semantic Scholar
Co-occurrence of symptoms after radiochemotherapy in locally advanced cervix cancer patients: a cluster analysis
Marta Pelizzola, K. Tanderup, S. Chopra, I. Jürgenliemk-Schulz +3 more
2023Acta oncologica8 citations Open access
Semantic Scholar
Image-Guided Brachytherapy for Rectal Cancer: Reviewing the Past Two Decades of Clinical Investigation
T. Vuong, A. Garant, V. Vendrely, R. Nout +5 more
2022Cancers8 citations Open access
Semantic Scholar
Distant metastasis after chemoradiation and IGABT in locally advanced cervical cancer.
J. Knoth, R. Nout, R. Pötter, U. Mahantshetty +25 more
2025International Journal of Radiation Oncology, Biology, Physics7 citations Open access
Semantic Scholar
EviGUIDE - A tool for evidence-based decision making in image-guided adaptive brachytherapy for cervical cancer.
S. Ecker, C. Kirisits, M. Schmid, J. Knoth +11 more
2023Radiotherapy and Oncology6 citations Open access
Semantic Scholar
Gynecological brachytherapy hybrid training: The Tata Memorial Centre and BrachyAcademy experience.
E. Dizendorf, S. Chopra, P. Mittal, Ankita Gupta +15 more
2024Brachytherapy4 citations Open access
Semantic Scholar
In Reply to Murakami et al.
A. Vittrup, S. Spampinato, N. Jensen, K. Tanderup +4 more
2023International Journal of Radiation Oncology, Biology, Physics4 citations
Semantic Scholar
Tools for large-scale data analytics of an international multi-center study in radiation oncology for cervical cancer.
S. Ecker, C. Kirisits, Maximilian Paul Schmid, Astrid Agatha Catharina De Leeuw +14 more
2023Radiotherapy and Oncology3 citations Open access
Semantic Scholar
Association between Regular Vaginal Dilation and/or Sexual Activity and Long-Term Vaginal Morbidity in Cervical Cancer Survivors.
K. Kirchheiner, A. Zaharie, S. Smet, S. Spampinato +16 more
2023International Journal of Radiation Oncology, Biology, Physics3 citations Open access
Semantic Scholar

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