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N. Azoitei · SciRah

Researcher profile · Semantic Scholar

N. Azoitei

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N. Azoitei — researcher profile on SciRah

h-index: 21
Works: 60
Citations: 2,783

Most-cited papers

NF-κB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression
M. Huber, N. Azoitei, B. Baumann, Stefan Grünert +5 more
2004784 citations Open access
Semantic Scholar
NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression.
M. Huber, N. Azoitei, B. Baumann, Stefan Grünert +5 more
2004Journal of Clinical Investigation542 citations
Semantic Scholar
PKM2 promotes tumor angiogenesis by regulating HIF-1α through NF-κB activation
N. Azoitei, Alexander Becher, K. Steinestel, A. Rouhi +4 more
2016Molecular Cancer306 citations Open access
Semantic Scholar
Variant classification in precision oncology
J. Leichsenring, P. Horák, S. Kreutzfeldt, C. Heining +39 more
2019International Journal of Cancer106 citations Open access
Semantic Scholar
Modelling Plasticity and Dysplasia of Pancreatic Ductal Organoids Derived from Human Pluripotent Stem Cells
M. Breunig, J. Merkle, M. Wagner, M. Melzer +33 more
2021Cell Stem Cell101 citations Open access
Semantic Scholar
ATM Deficiency Generating Genomic Instability Sensitizes Pancreatic Ductal Adenocarcinoma Cells to Therapy-Induced DNA Damage.
L. Perkhofer, A. Schmitt, M. C. Romero Carrasco, M. Ihle +22 more
2017Cancer Research95 citations
Semantic Scholar
Protein kinase D2 is a crucial regulator of tumour cell–endothelial cell communication in gastrointestinal tumours
N. Azoitei, G. Pusapati, A. Kleger, P. Möller +7 more
2010Gut79 citations
Semantic Scholar
Overexpression of Phospholipid-hydroperoxide Glutathione Peroxidase in Human Dermal Fibroblasts Abrogates UVA Irradiation-induced Expression of Interstitial Collagenase/Matrix Metalloproteinase-1 by Suppression of Phosphatidylcholine Hydroperoxide-mediated NFκB Activation and Interleukin-6 Release*
J. Wenk, Jutta Schüller, Christina Hinrichs, T. Syrovets +14 more
2004Journal of Biological Chemistry73 citations Open access
Semantic Scholar
Targeting of KRAS mutant tumors by HSP90 inhibitors involves degradation of STK33
N. Azoitei, Christopher M. Hoffmann, J. Ellegast, C. Ball +12 more
2012Journal of Experimental Medicine72 citations Open access
Semantic Scholar
Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer
J. Gout, L. Perkhofer, M. Morawe, F. Arnold +27 more
2020Gut66 citations Open access
Semantic Scholar
HSP90 Supports Tumor Growth and Angiogenesis through PRKD2 Protein Stabilization
N. Azoitei, Kristina Diepold, C. Brunner, A. Rouhi +9 more
2014Cancer Research54 citations Open access
Semantic Scholar
Physical plasma-triggered ROS induces tumor cell death upon cleavage of HSP90 chaperone
Sander Bekeschus, Maxi Lippert, Kristina Diepold, G. Chiosis +2 more
2019Scientific Reports44 citations Open access
Semantic Scholar
Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation.
N. Azoitei, A. Kleger, N. Schoo, D. Thal +11 more
2011Neuro-Oncology41 citations Open access
Semantic Scholar
Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure
M. Armacki, Anna Katharina Trugenberger, A. Ellwanger, T. Eiseler +30 more
2018Journal of Clinical Investigation39 citations Open access
Semantic Scholar
Thirty-eight-negative kinase 1 (TNK1) facilitates TNFα-induced apoptosis by blocking NF-κB activation
N. Azoitei, Andreas Brey, T. Busch, S. Fulda +2 more
2007Oncogene34 citations
Semantic Scholar
Requirement for YAP1 signaling in myxoid liposarcoma
M. Trautmann, Ya-Yun Cheng, Patrizia Jensen, N. Azoitei +20 more
2019EMBO Molecular Medicine31 citations Open access
Semantic Scholar
Adenosine receptor 2B activity promotes autonomous growth, migration as well as vascularization of head and neck squamous cell carcinoma cells
M. Wilkat, H. Bast, R. Drees, J. Dünser +14 more
2019Laryngo-Rhino-Otologie27 citations Open access
Semantic Scholar
Protein kinase D2: a versatile player in cancer biology
N. Azoitei, Mathias Cobbaut, Alexander Becher, J. Van Lint +1 more
2018Oncogene25 citations Open access
Semantic Scholar
CDKN2A-Mutated Pancreatic Ductal Organoids from Induced Pluripotent Stem Cells to Model a Cancer Predisposition Syndrome
J. Merkle, M. Breunig, M. Schmid, C. Allgöwer +12 more
2021Cancers24 citations Open access
Semantic Scholar
Activation of the IκB kinase complex is sufficient for neuronal differentiation of PC12 cells
N. Azoitei, T. Wirth, B. Baumann
2005Journal of Neurochemistry24 citations Open access
Semantic Scholar
Telomerase and Pluripotency Factors Jointly Regulate Stemness in Pancreatic Cancer Stem Cells
K. Walter, E. Rodríguez-Aznar, M. V. Ventura Ferreira, P. Frappart +21 more
2021Cancers23 citations Open access
Semantic Scholar
STK33 participates to HSP90-supported angiogenic program in hypoxic tumors by regulating HIF-1α/VEGF signaling pathway
Yang Liu, K. Steinestel, A. Rouhi, M. Armacki +5 more
2017OncoTarget20 citations Open access
Semantic Scholar
An Immunological Glance on Pancreatic Ductal Adenocarcinoma
M. Melzer, F. Arnold, K. Stifter, F. Zengerling +4 more
2020International Journal of Molecular Sciences18 citations Open access
Semantic Scholar
Functional Genomic Screening During Somatic Cell Reprogramming Identifies DKK3 as a Roadblock of Organ Regeneration
F. Arnold, Pallavi U. Mahaddalkar, J. Kraus, Xiao-Wei Zhong +25 more
2021Advancement of science16 citations Open access
Semantic Scholar
Enteropathogenic Infections: Organoids Go Bacterial
Viktoria Hentschel, F. Arnold, T. Seufferlein, N. Azoitei +2 more
2021Stem Cells International16 citations Open access
Semantic Scholar
Sildenafil triggers tumor lethality through altered expression of HSP90 and degradation of PKD2.
Lu Chen, Yang Liu, Alexander Becher, Kristina Diepold +8 more
2020Carcinogenesis15 citations Open access
Semantic Scholar
RINT1 Regulates SUMOylation and the DNA Damage Response to Preserve Cellular Homeostasis in Pancreatic Cancer
F. Arnold, J. Gout, Heike Wiese, S. Weissinger +19 more
2021Cancer Research13 citations
Semantic Scholar
Organoids at the PUB: The Porcine Urinary Bladder Serves as a Pancreatic Niche for Advanced Cancer Modeling
M. Melzer, M. Breunig, F. Arnold, F. Wezel +19 more
2022Advanced Healthcare Materials11 citations Open access
Semantic Scholar
Thirty-eight-negative kinase 1 (TNK1) facilitates TNFalpha-induced apoptosis by blocking NF-kappaB activation.
N. Azoitei, A. Brey, T. Busch, S. Fulda +2 more
2007Oncogene11 citations
Semantic Scholar
DNA methylation‐associated allelic inactivation regulates Keratin 19 gene expression during pancreatic development and carcinogenesis
J. Krüger, Anja Fischer, M. Breunig, C. Allgöwer +12 more
2023Journal of Pathology10 citations Open access
Semantic Scholar
PRKD2: A two-pronged kinase crucial for the tumor-supporting activity of HSP90
N. Azoitei, S. Fröhling, C. Scholl, T. Seufferlein
2015Molecular & Cellular Oncology10 citations Open access
Semantic Scholar
A time frame permissive for Protein Kinase D2 activity to direct angiogenesis in mouse embryonic stem cells
Martin Müller, Jana Schröer, N. Azoitei, T. Eiseler +10 more
2015Scientific Reports9 citations Open access
Semantic Scholar
Abstract 1809: PKM2 promotes tumor angiogenesis by regulating HIF-1alpha through NF-kappaB activation
N. Azoitei, Alexander Becher, K. Steinestel, A. Rouhi +3 more
20178 citations Open access
Semantic Scholar
BTK Isoforms p80 and p65 Are Expressed in Head and Neck Squamous Cell Carcinoma (HNSCC) and Involved in Tumor Progression
A. Betzler, H. Strobel, T. Abou Kors, J. Ezić +20 more
2023Cancers7 citations Open access
Semantic Scholar
Human Pluripotent Stem Cells Go Diabetic: A Glimpse on Monogenic Variants
S. Heller, M. Melzer, N. Azoitei, C. Julier +1 more
2021Frontiers in Endocrinology7 citations Open access
Semantic Scholar
Unveiling the intriguing relationship: oncogenic KRAS , morphological shifts, and mutational complexity in pancreatic mucinous cystic neoplasms
L. Schulte, Annika Beck, R. Marienfeld, N. Azoitei +19 more
2025Journal of Pathology5 citations Open access
Semantic Scholar
Functional Genomic Screening in Human Pluripotent Stem Cells Reveals New Roadblocks in Early Pancreatic Endoderm Formation
J. Krüger, M. Breunig, L. Pasquini, M. Morawe +10 more
2022Cells4 citations Open access
Semantic Scholar
Reconstructing tumor tissues in 3D: From organoids to bioengineered niches.
V. Kast, F. Navaee, Majid Halvaei, S. Liebau +4 more
2026Cell Stem Cell3 citations Open access
Semantic Scholar
Preliminary estimation of the Y Alu polymorphic (YAP) element in the Romanian population.
G. Stefanescu, M. Caraghin, N. Azoitei, A. Azoitei
1997Gene geography : a computerized bulletin on human gene frequencies3 citations
Semantic Scholar
Novel peptide targeting CXCR4 disrupt tumor-stroma crosstalk to eliminate migrating cancer stem cells
K. Tiwary, A. Lahusen, S. Inaas, Bastian Beitzinger +15 more
2025bioRxiv2 citations Open access
Semantic Scholar
DKK3 Initially Preserves Acinar Integrity Through MEK‐Fos Signaling, but Later Switches to an Oncogenic Role in Pancreatic Cancer
Dharini Srinivasan, E. Roger, L. Perkhofer, Eleni Zimmer +17 more
2025Advancement of science2 citations Open access
Semantic Scholar
Pancreatic cancer stem cells (CSCs) are regulated via a feedback-loop of telomerase activity and stemness factors Telomerase activity is important for pancreatic CSCs maintenance
K. Walter, E. Rodríguez-Aznar, M. V. Ventura Ferreira, P. Frappart +19 more
2020bioRxiv1 citations Open access
Semantic Scholar
A feedback-loop between telomerase activity and stemness factors regulates PDAC stem cells
K. Walter, E. Rodríguez-Aznar, M. V. Ventura Ferreira, P. Frappart +19 more
20201 citations Open access
Semantic Scholar
Thirty-eight-negative-kinase-1 is a major mediator of trauma-induced intestinal injury and multi-organ failure
M. Armacki, A. Trugenberger, A. Ellwanger, T. Eiseler +16 more
2018Zeitschrift für Gastroenterologie - German Journal of Gastroenterology1 citations
Semantic Scholar
NF-k B is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression
M. Huber, N. Azoitei, B. Baumann, Stefan Grünert +5 more
20181 citations
Semantic Scholar
A deep learning approach to assess transendothelial cell trafficking performance
T. Schumacher, Elisabeth Marie Gottloeber, Eric Koziel, M. Saçma +14 more
2026Scientific Reports0 citations Open access
Semantic Scholar
A CXCR4 targeting peptide delivered by silica nanoparticles eliminates migrating cancer stem cells in pancreatic ductal adenocarcinoma
K. Tiwary, A. Lahusen, S. Inaas, Bastian Beitzinger +15 more
2026Scientific Reports0 citations Open access
Semantic Scholar
Pandemic punch: SARS-CoV-2 hits pancreas
N. Azoitei, Sandra Heller, A. Kleger
2024Signal Transduction and Targeted Therapy0 citations Open access
Semantic Scholar
Allelic regulation of Keratin 19 gene expression during pancreatic development and carcinogenesis
J. Krüger, A. Fischer, M. Breunig, C. Allgöwer +10 more
2023Pancreatology (Print)0 citations
Semantic Scholar
Abstract 3437: Requirement for YAP1 signaling in myxoid liposarcoma
M. Trautmann, Ya-Yun Cheng, Patrizia Jensen, N. Azoitei +19 more
2019Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar

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