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L. Tabernero · SciRah

Researcher profile · Semantic Scholar

L. Tabernero

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L. Tabernero — researcher profile on SciRah

h-index: 28
Works: 74
Citations: 2,414

Most-cited papers

Molecular Mechanisms of Primary Resistance to Flucytosine in Candida albicans
W. Hope, L. Tabernero, D. Denning, Michael J. Anderson
2004Antimicrobial Agents and Chemotherapy158 citations Open access
Semantic Scholar
Protein tyrosine phosphatases: structure–function relationships
L. Tabernero, A. R. Aricescu, E. Y. Jones, S. Szedlacsek
2008The FEBS Journal154 citations
Semantic Scholar
Hyper-adhesion in desmosomes: its regulation in wound healing and possible relationship to cadherin crystal structure
D. Garrod, M. Berika, William F Bardsley, D. Holmes +1 more
2005Journal of Cell Science153 citations Open access
Semantic Scholar
Dual-specificity MAP kinase phosphatases as targets of cancer treatment.
C. Nunes-Xavier, C. Romá-Mateo, P. Ríos, Céline Tárrega +3 more
2011Anti-Cancer Agents in Medicinal Chemistry122 citations
Semantic Scholar
Protein tyrosine phosphatase TbPTP1: a molecular switch controlling life cycle differentiation in trypanosomes
B. Szöőr, Jude Wilson, Helen McElhinney, L. Tabernero +1 more
2006Journal of Cell Biology114 citations Open access
Semantic Scholar
MptpB, a virulence factor from Mycobacterium tuberculosis, exhibits triple-specificity phosphatase activity.
Nicola J. Beresford, S. Patel, J. Armstrong, B. Szöőr +2 more
2007Biochemical Journal103 citations Open access
Semantic Scholar
The TriTryp Phosphatome: analysis of the protein phosphatase catalytic domains
R. Brenchley, Humera Tariq, Helen McElhinney, B. Szöőr +4 more
2007BMC Genomics98 citations Open access
Semantic Scholar
Molecular structure of the A-tract DNA dodecamer d(CGCAAATTTGCG) complexed with the minor groove binding drug netropsin.
L. Tabernero, N. Verdaguer, M. Coll, I. Fita +4 more
1993Biochemistry91 citations
Semantic Scholar
Inhibition of MptpB phosphatase from Mycobacterium tuberculosis impairs mycobacterial survival in macrophages.
Nicola J. Beresford, Debbie C. Mulhearn, B. Szczepankiewicz, Gang Liu +5 more
2009Journal of Antimicrobial Chemotherapy87 citations
Semantic Scholar
Substrate-induced closure of the flap domain in the ternary complex structures provides insights into the mechanism of catalysis by 3-hydroxy-3-methylglutaryl-CoA reductase.
L. Tabernero, D. Bochar, V. Rodwell, C. Stauffacher
1999Proceedings of the National Academy of Sciences of the United States of America86 citations Open access
Semantic Scholar
Protein tyrosine phosphatase structure–function relationships in regulation and pathogenesis
F. Böhmer, S. Szedlacsek, L. Tabernero, A. Östman +1 more
2013The FEBS Journal85 citations
Semantic Scholar
Dual-Specificity Phosphatases as Molecular Targets for Inhibition in Human Disease
P. Ríos, C. Nunes-Xavier, L. Tabernero, Maja Köhn +1 more
2014Antioxidants and Redox Signaling80 citations
Semantic Scholar
Membrane-impermeable Cross-linking Provides Evidence for Homophilic, Isoform-specific Binding of Desmosomal Cadherins in Epithelial Cells*♦
Zhuxiang Nie, A. Merritt, Mansour Rouhi-Parkouhi, L. Tabernero +1 more
2010Journal of Biological Chemistry74 citations Open access
Semantic Scholar
Protein classification using ontology classification
K. Wolstencroft, P. Lord, L. Tabernero, A. Brass +1 more
2006Intelligent Systems in Molecular Biology65 citations Open access
Semantic Scholar
Crystal structures of a low-molecular weight protein tyrosine phosphatase from Saccharomyces cerevisiae and its complex with the substrate p-nitrophenyl phosphate.
Shuishu Wang, L. Tabernero, Marie Zhang, E. Harms +2 more
2000Biochemistry58 citations
Semantic Scholar
Crystal Structure of the Catalytic Domain of the Mitotic Checkpoint Kinase Mps1 in Complex with SP600125*
M. Chu, L. Chavas, K. Douglas, P. Eyers +1 more
2008Journal of Biological Chemistry56 citations Open access
Semantic Scholar
Crystal Structure of a Statin Bound to a Class II Hydroxymethylglutaryl-CoA Reductase*
L. Tabernero, V. Rodwell, C. Stauffacher
2003Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Class II 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductases
M. Hedl, L. Tabernero, C. Stauffacher, V. Rodwell
2004Journal of Bacteriology46 citations Open access
Semantic Scholar
Structure-Based Design of MptpB Inhibitors That Reduce Multidrug-Resistant Mycobacterium tuberculosis Survival and Infection Burden in Vivo
Clare Vickers, Ana P G Silva, Ajanta Chakraborty, P. Fernández +12 more
2018Journal of Medicinal Chemistry45 citations Open access
Semantic Scholar
Cadherin flexibility provides a key difference between desmosomes and adherens junctions
Humera Tariq, J. Bella, T. Jowitt, D. F. Holmes +5 more
2015Proceedings of the National Academy of Sciences of the United States of America38 citations Open access
Semantic Scholar
Constructing ontology-driven protein family databases
K. Wolstencroft, R. McEntire, Robert Stevens, L. Tabernero +1 more
2005Bioinform.37 citations Open access
Semantic Scholar
The molecular basis for selective assembly of the UBAP1-containing endosome-specific ESCRT-I complex
Lydia Wunderley, Kim Brownhill, Flavia Stefani, L. Tabernero +1 more
2014Journal of Cell Science34 citations Open access
Semantic Scholar
Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes.
M. Chu, Z. Lang, L. Chavas, J. Neres +6 more
2010Biochemistry34 citations
Semantic Scholar
Hyper-adhesion: A Unique Property of Desmosomes
D. Garrod, L. Tabernero
2014Cell Communication & Adhesion31 citations Open access
Semantic Scholar
Phylogenetic and genetic linkage between novel atypical dual-specificity phosphatases from non-metazoan organisms
C. Romá-Mateo, Almudena Sacristán-Reviriego, Nicola J. Beresford, J. A. Caparrós-Martín +5 more
2011Zeitschrift für Induktive Abstammungs- und Vererbungslehre30 citations Open access
Semantic Scholar
Dissecting the role of His domain protein tyrosine phosphatase/PTPN23 and ESCRTs in sorting activated epidermal growth factor receptor to the multivesicular body
L. Tabernero, P. Woodman
2018Biochemical Society Transactions29 citations Open access
Semantic Scholar
The structure of the bovine protein tyrosine phosphatase dimer reveals a potential self-regulation mechanism.
L. Tabernero, B. Evans, P. Tishmack, R. L. van Etten +1 more
1999Biochemistry29 citations
Semantic Scholar
Crystallographic determination of the structures of human α‐thrombin complexed with BMS‐186282 and BMS‐189090
M. Malley, J. Sack, L. Tabernero, Chieh-Ying Y. Chang +3 more
199629 citations Open access
Semantic Scholar
Structural Basis for Selective Interaction between the ESCRT Regulator HD-PTP and UBAP1
D. Gahloth, C. Levy, G. Heaven, Flavia Stefani +7 more
2016Structure28 citations Open access
Semantic Scholar
The open architecture of HD-PTP phosphatase provides new insights into the mechanism of regulation of ESCRT function
D. Gahloth, G. Heaven, T. Jowitt, A. Mould +4 more
2017Scientific Reports27 citations Open access
Semantic Scholar
A new family of phosphoinositide phosphatases in microorganisms: identification and biochemical analysis
Nicola J. Beresford, Charis R. Saville, H. Bennett, I. Roberts +1 more
2010BMC Genomics27 citations Open access
Semantic Scholar
A novel phosphatase family, structurally related to dual-specificity phosphatases, that displays unique amino acid sequence and substrate specificity.
C. Romá-Mateo, P. Ríos, L. Tabernero, T. Attwood +1 more
2007Journal of Molecular Biology27 citations
Semantic Scholar
ERK2 Shows a Restrictive and Locally Selective Mechanism of Recognition by Its Tyrosine Phosphatase Inactivators Not Shared by Its Activator MEK1*
Céline Tárrega, P. Ríos, R. Cejudo-Marín, C. Blanco-Aparicio +5 more
2005Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Mechanism of catalysis and inhibition of Mycobacterium tuberculosis SapM, implications for the development of novel antivirulence drugs
Paulina Fernandez-Soto, A. Bruce, Alistair J. Fielding, J. Cavet +1 more
2019Scientific Reports24 citations Open access
Semantic Scholar
Characterization of an HMG-CoA reductase from Listeria monocytogenes that exhibits dual coenzyme specificity.
Amy E Theivagt, E. Amanti, Nicola J. Beresford, L. Tabernero +1 more
2006Biochemistry24 citations
Semantic Scholar
New strategies in fighting TB: targeting Mycobacterium tuberculosis-secreted phosphatases MptpA & MptpB.
Ana P G Silva, L. Tabernero
2010Future Medicinal Chemistry22 citations
Semantic Scholar
PhosphaBase: An ontology‐driven database resource for protein phosphatases
K. Wolstencroft, Robert Stevens, L. Tabernero, A. Brass
2004Proteins: Structure, Function, and Bioinformatics21 citations
Semantic Scholar
VSpipe, an Integrated Resource for Virtual Screening and Hit Selection: Applications to Protein Tyrosine Phospahatase Inhibition
Sandra Álvarez-Carretero, Niki Pavlopoulou, J. Adams, J. Gilsenan +1 more
2018Molecules17 citations Open access
Semantic Scholar
Characteristics of the First Protein Tyrosine Phosphatase with Phytase Activity from a Soil Metagenome
Genis Andrés Castillo Villamizar, H. Nacke, Laura Griese, L. Tabernero +2 more
2019Genes16 citations Open access
Semantic Scholar
Targeting Methionine Synthase in a Fungal Pathogen Causes a Metabolic Imbalance That Impacts Cell Energetics, Growth, and Virulence
Jennifer Scott, Mónica Sueiro-Olivares, B. P. Thornton, R. Owens +10 more
2020mBio14 citations Open access
Semantic Scholar
Supplemental Information Structural Basis for Specific Interaction of TGFb Signaling Regulators SARA/Endofin with HD-PTP
C. Levy, L. Walker, Lydia Wunderley, Sandra +3 more
201714 citations
Semantic Scholar
Functional assignment of MAPK phosphatase domains
Anna K. L. Nordle, P. Ríos, A. Gaulton, R. Pulido +2 more
2007Proteins: Structure, Function, and Bioinformatics14 citations
Semantic Scholar
A Founder Mutation in EHD1 Presents with Tubular Proteinuria and Deafness
N. Issler, Sara Afonso, I. Weissman, Katrin Jordan +46 more
2022Journal of the American Society of Nephrology12 citations Open access
Semantic Scholar
Targeting methionine synthase in a fungal pathogen causes a metabolic imbalance that impacts cell energetics, growth and virulence
Jennifer Scott, Mónica Sueiro-Olivares, B. P. Thornton, R. Owens +10 more
2020bioRxiv12 citations Open access
Semantic Scholar
Discovery of uncompetitive inhibitors of SapM that compromise intracellular survival of Mycobacterium tuberculosis
Paulina Fernandez-Soto, J. Casulli, Danilo Solano-Castro, P. Rodríguez Fernández +4 more
2021Scientific Reports11 citations Open access
Semantic Scholar
Identification of Functional and Druggable Sites in Aspergillus fumigatus Essential Phosphatases by Virtual Screening
B. P. Thornton, A. Johns, Reem Al-Shidhani, Sandra Álvarez-Carretero +3 more
2019International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
Regulation of dual specificity phosphatases in breast cancer during initial treatment with Herceptin: a Boolean model analysis
Petronela Buiga, A. Elson, L. Tabernero, Jean-Marc Schwartz
2018BMC Systems Biology9 citations Open access
Semantic Scholar
Using Ontology Reasoning to Classify Protein Phosphatases
K. Wolstencroft, P. Lord, L. Tabernero, A. Brass +1 more
20058 citations
Semantic Scholar
Characterization of the atypical Ppz/Hal3 phosphatase system from the pathogenic fungus Cryptococcus neoformans
Chun-Yi Zhang, Rocio Garcia-Rodas, C. Molero, H. C. de Oliveira +4 more
2019Molecular Microbiology7 citations Open access
Semantic Scholar
A New Paradigm for KIM-PTP Drug Discovery: Identification of Allosteric Sites with Potential for Selective Inhibition Using Virtual Screening and LEI Analysis
J. Adams, B. P. Thornton, L. Tabernero
2021International Journal of Molecular Sciences5 citations Open access
Semantic Scholar

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