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M. Chu · SciRah

Researcher profile · Semantic Scholar

M. Chu

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M. Chu — researcher profile on SciRah

h-index: 15
Works: 23
Citations: 1,888

Most-cited papers

Cryo-EM structure of the activated GLP-1 receptor in complex with G protein
Yan Zhang, Bingfa Sun, D. Feng, Hong-Li Hu +7 more
2017Nature537 citations Open access
Semantic Scholar
Structural Insights into Metabotropic Glutamate Receptor Activation
A. Koehl, Hong-Li Hu, D. Feng, Bingfa Sun +13 more
2019Nature274 citations Open access
Semantic Scholar
Structural basis of Wnt signaling inhibition by Dickkopf binding to LRP5/6
V. Ahn, M. Chu, Hee-Jung Choi, D. Tran +2 more
2011Developmental Cell207 citations Open access
Semantic Scholar
Structural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6
J. Stamos, M. Chu, M. Enos, N. Shah +1 more
2014eLife175 citations Open access
Semantic Scholar
Crystal structure of the adenosine A2A receptor bound to an antagonist reveals a potential allosteric pocket
Bingfa Sun, P. Bachhawat, M. Chu, M. Wood +6 more
2017Proceedings of the National Academy of Sciences of the United States of America127 citations Open access
Semantic Scholar
Drug-resistant aurora A mutants for cellular target validation of the small molecule kinase inhibitors MLN8054 and MLN8237.
D. Sloane, M. Trikić, M. Chu, M. Lamers +5 more
2010ACS Chemical Biology121 citations Open access
Semantic Scholar
Structural studies of Wnts and identification of an LRP6 binding site
M. Chu, V. Ahn, Hee-Jung Choi, D. Daniels +2 more
2013Structure89 citations Open access
Semantic Scholar
Discovery and Exploitation of Inhibitor-resistant Aurora and Polo Kinase Mutants for the Analysis of Mitotic Networks◆
P. Scutt, M. Chu, D. Sloane, M. Cherry +3 more
2009Journal of Biological Chemistry69 citations Open access
Semantic Scholar
Crystal Structure of the Catalytic Domain of the Mitotic Checkpoint Kinase Mps1 in Complex with SP600125*
M. Chu, L. Chavas, K. Douglas, P. Eyers +1 more
2008Journal of Biological Chemistry56 citations Open access
Semantic Scholar
Crystal structure of dopamine D1 receptor in complex with G protein and a non-catechol agonist
Bingfa Sun, D. Feng, M. Chu, I. Fish +9 more
2021Nature Communications53 citations Open access
Semantic Scholar
Phosphoregulation of human Mps1 kinase.
R. K. Tyler, M. Chu, H. Reeves (Johnson), E. Mckenzie +2 more
2009Biochemical Journal53 citations Open access
Semantic Scholar
One size does not fit all: navigating the multi-dimensional space to optimize T-cell engaging protein therapeutics
Wei Chen, Fan Yang, Carole Wang, J. Narula +12 more
2021mAbs49 citations Open access
Semantic Scholar
Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes.
M. Chu, Z. Lang, L. Chavas, J. Neres +6 more
2010Biochemistry34 citations
Semantic Scholar
Ligand-Blocking and Membrane-Proximal Domain Targeting Anti-OX40 Antibodies Mediate Potent T Cell-Stimulatory and Anti-Tumor Activity.
Pamela Zhang, G. Tu, Jie Wei, Pamela Santiago +10 more
2019Cell Reports21 citations Open access
Semantic Scholar
Metabotropic Glutamate Receptor 5 Extracellular Domain in Complex with Nb43 and L-quisqualic acid
A. Koehl, H. Hu, D. Feng, B. Sun +5 more
201919 citations
Semantic Scholar
Author Correction: Structural insights into the activation of metabotropic glutamate receptors
A. Koehl, Hong-Li Hu, D. Feng, Bingfa Sun +13 more
2019Nature4 citations Open access
Semantic Scholar
Biochemical and structural analysis of the human kinase MPS1
M. Chu
20092 citations
Semantic Scholar
Phosphoregulation of human Mps 1 kinase
R. K. Tyler, M. Chu, H. Reeves (Johnson), E. Mckenzie +2 more
20082 citations
Semantic Scholar
Author response: Structural basis of GSK-3 inhibition by N-terminal phosphorylation and by the Wnt receptor LRP6
J. Stamos, M. Chu, M. Enos, N. Shah +1 more
20141 citations Open access
Semantic Scholar
Crystal structure of human Mps1 catalytic domain in complex with a quinazolin ligand Compound 4
M. Chu, L. Chavas, D. H. Williams, L. Tabernero +1 more
20100 citations
Semantic Scholar
Crystal structure of human Mps1 catalytic domain in complex with the inhibitor staurosporine
M. Chu, L. Chavas, D. H. Williams, L. Tabernero +1 more
20100 citations
Semantic Scholar
Crystal structure of human Mps1 catalytic domain in complex with ATP
M. Chu, L. Chavas, D. H. Williams, L. Tabernero +1 more
20100 citations
Semantic Scholar
Crystal structure of human mitotic checkpoint kinase Mps1 catalytic domain apo form
M. Chu, L. Chavas, K. T. Douglas, P. Eyers +1 more
20080 citations
Semantic Scholar

Frequent co-authors

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P. Eyers×10
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P. Eyers — researcher profile on SciRah
B. Kobilka×6
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B. Kobilka — researcher profile on SciRah
W. Weis×6
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W. Weis — researcher profile on SciRah
L. Chavas×6
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D. Feng — researcher profile on SciRah

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Bingfa Sun — researcher profile on SciRah

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T. S. Kobilka×4

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