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Jens M. Moll · SciRah

Researcher profile · Semantic Scholar

Jens M. Moll

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Jens M. Moll — researcher profile on SciRah

h-index: 18
Works: 36
Citations: 1,652

Most-cited papers

Targeting IL-6 trans-signalling: past, present and future prospects
S. Rose-John, B. Jenkins, Christoph Garbers, Jens M. Moll +1 more
2023Nature reviews. Immunology474 citations Open access
Semantic Scholar
The balance of interleukin (IL)-6, IL-6·soluble IL-6 receptor (sIL-6R), and IL-6·sIL-6R·sgp130 complexes allows simultaneous classic and trans-signaling
Paul Baran, S. Hansen, G. H. Waetzig, M. Akbarzadeh +5 more
2018Journal of Biological Chemistry206 citations Open access
Semantic Scholar
Rho-kinase: regulation, (dys)function, and inhibition
Ehsan Amin, B. Dubey, Si-Cai Zhang, L. Gremer +7 more
2013Biological chemistry162 citations Open access
Semantic Scholar
IL‐6 Trans‐signaling Controls Liver Regeneration After Partial Hepatectomy
Nastaran Fazel Modares, Robin Polz, F. Haghighi, Larissa Lamertz +12 more
2019Hepatology89 citations
Semantic Scholar
Soluble gp130 prevents interleukin-6 and interleukin-11 cluster signaling but not intracellular autocrine responses
Larissa Lamertz, Franziska Rummel, Robin Polz, Paul Baran +5 more
2018Science Signaling68 citations
Semantic Scholar
IL-12 and IL-23—Close Relatives with Structural Homologies but Distinct Immunological Functions
D. Floss, Jens M. Moll, J. Scheller
2020Cells65 citations Open access
Semantic Scholar
Synthetic cytokine receptors transmit biological signals using artificial ligands
E. Engelowski, A. Schneider, M. Franke, Hai-Feng C. Xu +10 more
2018Nature Communications61 citations Open access
Semantic Scholar
Subcellular Fractionation and Localization Studies Reveal a Direct Interaction of the Fragile X Mental Retardation Protein (FMRP) with Nucleolin
M. S. Taha, K. Nouri, L. Milroy, Jens M. Moll +4 more
2014PLoS ONE61 citations Open access
Semantic Scholar
Titin-Based Cardiac Myocyte Stiffening Contributes to Early Adaptive Ventricular Remodeling After Myocardial Infarction.
Sebastian Kötter, Malgorzata Kazmierowska, Christian Andresen, K. Bottermann +9 more
2016Circulation Research46 citations Open access
Semantic Scholar
Non-Canonical Interleukin 23 Receptor Complex Assembly
Jutta Schröder, Jens M. Moll, Paul Baran, J. Grötzinger +2 more
2014Journal of Biological Chemistry41 citations Open access
Semantic Scholar
Alternative Intronic Polyadenylation Generates the Interleukin-6 Trans-signaling Inhibitor sgp130-E10*
Jan Sommer, Christoph Garbers, J. Wolf, Ahmad Trad +7 more
2014Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Immunoreceptor Engineering and Synthetic Cytokine Signaling for Therapeutics.
J. Scheller, E. Engelowski, Jens M. Moll, D. Floss
2019Trends in immunology32 citations
Semantic Scholar
Selective inhibition of IL-6 trans-signaling by a miniaturized, optimized chimeric soluble gp130 inhibits TH17 cell expansion
Denise Heise, Alicia Derrac Soria, S. Hansen, Christine Dambietz +8 more
2021Science Signaling31 citations
Semantic Scholar
Non-invasive mapping of systemic neutrophil dynamics upon cardiovascular injury
P. Bouvain, Z. Ding, Shiwa Kadir, Patricia Kleimann +25 more
2023Nature Cardiovascular Research30 citations Open access
Semantic Scholar
Exclusive inhibition of IL-6 trans-signaling by soluble gp130FlyRFc
Anna F. Berg, Julia Ettich, Hendrik T. Weitz, Matthias Krusche +3 more
2021Cytokine: X30 citations Open access
Semantic Scholar
Transcytosis of IL-11 and Apical Redirection of gp130 Is Mediated by IL-11α Receptor.
N. Monhasery, Jens M. Moll, C. Cuman, M. Franke +10 more
2016Cell Reports29 citations Open access
Semantic Scholar
Biophysical Characterization of Nucleophosmin Interactions with Human Immunodeficiency Virus Rev and Herpes Simplex Virus US11
K. Nouri, Jens M. Moll, L. Milroy, Anika Hain +11 more
2015PLoS ONE29 citations Open access
Semantic Scholar
Recombinant p35 from Bacteria Can Form Interleukin (IL-)12, but Not IL-35
Samadhi Aparicio-Siegmund, Jens M. Moll, J. Lokau, M. Grusdat +7 more
2014PLoS ONE25 citations Open access
Semantic Scholar
Synthetic Cargo Internalization Receptor System for Nanoparticle Tracking of Individual Cell Populations by Fluorine Magnetic Resonance Imaging.
S. Temme, Paul Baran, P. Bouvain, C. Grapentin +9 more
2018ACS Nano18 citations
Semantic Scholar
Deciphering site 3 interactions of interleukin 12 and interleukin 23 with their cognate murine and human receptors
Alessandra Esch, A. Masiarz, Sofie Mossner, Jens M. Moll +4 more
2020Journal of Biological Chemistry17 citations Open access
Semantic Scholar
Bispecific soluble cytokine receptor-nanobody fusions inhibit Interleukin (IL-)6 trans-signaling and IL-12/23 or tumor necrosis factor (TNF) signaling
Annika Gesiorowski, Julia Ettich, Julia Werner, Christoph Wittich +7 more
2023Journal of Biological Chemistry16 citations Open access
Semantic Scholar
Multimerization strategies for efficient production and purification of highly active synthetic cytokine receptor ligands
Sofie Mossner, H. T. Phan, Saskia Triller, Jens M. Moll +2 more
2020PLoS ONE13 citations Open access
Semantic Scholar
Interleukin‐11 receptor is an alternative α‐receptor for interleukin‐6 and the chimeric cytokine IC7
Hendrik T. Weitz, Julia Ettich, P. Rafii, Christoph Wittich +11 more
2024The FEBS Journal10 citations Open access
Semantic Scholar
Cytokimera GIL-11 rescued IL-6R deficient mice from partial hepatectomy-induced death by signaling via non-natural gp130:LIFR:IL-11R complexes
P. Rafii, Christiane Seibel, Hendrik T. Weitz, Julia Ettich +8 more
2023Communications Biology10 citations Open access
Semantic Scholar
A Hybrid Soluble gp130/Spike-Nanobody Fusion Protein Simultaneously Blocks Interleukin-6 trans-Signaling and Cellular Infection with SARS-CoV-2
Julia Ettich, Julia Werner, Hendrik T. Weitz, Eva-Christina Mueller +4 more
2021Journal of Virology10 citations Open access
Semantic Scholar
Current status and relevance of single nucleotide polymorphisms in IL-6-/IL-12-type cytokine receptors.
J. Scheller, A. Berg, Jens M. Moll, D. Floss +1 more
2021Cytokine10 citations
Semantic Scholar
Engineered interleukin-6-derived cytokines recruit artificial receptor complexes and disclose CNTF signaling via the OSMR
P. Rafii, Patricia Rodrigues Cruz, Julia Ettich, Christiane Seibel +8 more
2024Journal of Biological Chemistry9 citations Open access
Semantic Scholar
Tryptophan (W) at position 37 of murine IL-12/IL-23 p40 is mandatory for binding to IL-12Rβ1 and subsequent signal transduction
Jacqueline Georgy, Yvonne Arlt, Jens M. Moll, M. Ouzin +7 more
2021Journal of Biological Chemistry9 citations Open access
Semantic Scholar
Split2 Protein-Ligation Generates Active IL-6-Type Hyper-Cytokines from Inactive Precursors.
Jens M. Moll, Melanie Wehmöller, Nils C Frank, Lisa Homey +7 more
2017ACS Synthetic Biology8 citations
Semantic Scholar
Respiratory syncytial virus–approved mAb Palivizumab as ligand for anti-idiotype nanobody-based synthetic cytokine receptors
Julia Ettich, Christoph Wittich, Jens M. Moll, K. Behnke +7 more
2023Journal of Biological Chemistry5 citations Open access
Semantic Scholar
Targeting the major pro-inflammatory interleukin-6-type cytokine receptor gp130 by antagonistic single domain antibodies
Silke Pudewell, J. Heuser, Inna Dorogobed, Britta Lipinski +9 more
2025Frontiers in Immunology3 citations Open access
Semantic Scholar
Correction: Multimerization strategies for efficient production and purification of highly active synthetic cytokine receptor ligands
Sofie Mossner, H. T. Phan, Saskia Triller, Jens M. Moll +2 more
2020PLoS ONE1 citations Open access
Semantic Scholar
Synthetic receptor platform to identify loss-of-function single nucleotide variants and designed mutants in the death receptor Fas/CD95
Annamaria Minafra, P. Rafii, Sofie Mossner, Farhad Bazgir +3 more
2023Journal of Biological Chemistry0 citations Open access
Semantic Scholar
Synthetic cytokine receptors transmit biological signals using artificial ligands
E. Engelowski, A. Schneider, M. Franke, Hai-Feng C. Xu +10 more
2018Nature Communications0 citations Open access
Semantic Scholar
Adaptive Ventricular Remodelling after Myocardial Infarction Involves Titin-Based Cardiomyocyte Stiffening and Elevated Titin Turnover
Sebastian Kötter, Malgorzata Kazmierowska, Christian Andresen, K. Bottermann +9 more
20170 citations Open access
Semantic Scholar
ID: 162: Split2-cytokine protein-ligation: Non-toxic and background-free induction of Interleukin (IL-)6 Trans-signaling by split-intein mediated protein ligation of biologically inactive split-IL-6 in vivo
Jens M. Moll, Melanie Wehmöller, Lisa Homey, Nils C Frank +6 more
20150 citations
Semantic Scholar

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