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L. Varesio · SciRah

Researcher profile · Semantic Scholar

L. Varesio

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L. Varesio — researcher profile on SciRah

h-index: 50
Works: 246
Citations: 9,573

Most-cited papers

Mesenchymal Stem Cell‐Derived Extracellular Vesicles as Mediators of Anti‐Inflammatory Effects: Endorsement of Macrophage Polarization
Claudia Lo Sicco, D. Reverberi, C. Balbi, V. Ulivi +9 more
2017Stem Cells Translational Medicine516 citations Open access
Semantic Scholar
ResearchA biology-driven approach identifies the hypoxia gene signature as a predictor of the outcome of neuroblastoma patients
Paolo Fardin, A. Barla, S. Mosci, L. Rosasco +8 more
2010490 citations
Semantic Scholar
LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression
J. Molenaar, R. Domingo-Fernández, M. E. Ebus, S. Lindner +26 more
2012Nature Genetics389 citations Open access
Semantic Scholar
Hypoxia downregulates the expression of activating receptors involved in NK‐cell‐mediated target cell killing without affecting ADCC
M. Balsamo, Claudia Manzini, G. Pietra, Federica Raggi +6 more
2013European Journal of Immunology265 citations Open access
Semantic Scholar
Regulation of Human Macrophage M1–M2 Polarization Balance by Hypoxia and the Triggering Receptor Expressed on Myeloid Cells-1
Federica Raggi, Simone Pelassa, D. Pierobon, F. Penco +6 more
2017Frontiers in Immunology261 citations Open access
Semantic Scholar
Monocytes and dendritic cells in a hypoxic environment: Spotlights on chemotaxis and migration.
M. C. Bosco, M. Puppo, F. Blengio, Tiziana Fraone +3 more
2008Immunobiology182 citations
Semantic Scholar
The P2X7 receptor is a key modulator of the PI3K/GSK3β/VEGF signaling network: evidence in experimental neuroblastoma
F. Amoroso, Marina Capece, A. Rotondo, Davide Cangelosi +6 more
2015Oncogene167 citations Open access
Semantic Scholar
Cytokines induce tight junction disassembly in airway cells via an EGFR-dependent MAPK/ERK1/2-pathway
L. Petecchia, F. Sabatini, C. Usai, E. Caci +2 more
2012Laboratory Investigation148 citations Open access
Semantic Scholar
Hypoxia Modifies the Transcriptome of Human NK Cells, Modulates Their Immunoregulatory Profile, and Influences NK Cell Subset Migration
M. Parodi, Federica Raggi, Davide Cangelosi, Claudia Manzini +9 more
2018Frontiers in Immunology135 citations Open access
Semantic Scholar
Hypoxia modulates the gene expression profile of immunoregulatory receptors in human mature dendritic cells: identification of TREM-1 as a novel hypoxic marker in vitro and in vivo.
M. C. Bosco, D. Pierobon, F. Blengio, Federica Raggi +7 more
2011Blood127 citations Open access
Semantic Scholar
First Characterization of Human Amniotic Fluid Stem Cell Extracellular Vesicles as a Powerful Paracrine Tool Endowed with Regenerative Potential
C. Balbi, M. Piccoli, L. Barile, Andrea Papait +12 more
2017Stem Cells Translational Medicine119 citations Open access
Semantic Scholar
Human dendritic cells differentiated in hypoxia down‐modulate antigen uptake and change their chemokine expression profile
A. R. Elia, P. Cappello, M. Puppo, Tiziana Fraone +6 more
2008Journal of Leukocyte Biology106 citations Open access
Semantic Scholar
Transcriptome of Hypoxic Immature Dendritic Cells: Modulation of Chemokine/Receptor Expression
A. Ricciardi, A. R. Elia, P. Cappello, M. Puppo +7 more
2008Molecular Cancer Research105 citations Open access
Semantic Scholar
Bronchial airway epithelial cell damage following exposure to cigarette smoke includes disassembly of tight junction components mediated by the extracellular signal-regulated kinase 1/2 pathway.
L. Petecchia, F. Sabatini, L. Varesio, A. Camoirano +3 more
2009Chest103 citations
Semantic Scholar
Genomic Amplifications and Distal 6q Loss: Novel Markers for Poor Survival in High-risk Neuroblastoma Patients
P. Depuydt, V. Boeva, T. Hocking, Robrecht Cannoodt +31 more
2018Journal of the National Cancer Institute88 citations Open access
Semantic Scholar
Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1α and -2α
M. Puppo, F. Battaglia, C. Ottaviano, S. Delfino +3 more
2008Molecular Cancer Therapeutics82 citations Open access
Semantic Scholar
The hypoxic environment reprograms the cytokine/chemokine expression profile of human mature dendritic cells.
F. Blengio, Federica Raggi, D. Pierobon, P. Cappello +4 more
2013Immunobiology71 citations
Semantic Scholar
Synergystic induction of HIF-1α transcriptional activity by hypoxia and lipopolysaccharide in macrophages
Z. Mi, A. Rapisarda, L. Taylor, A. Brooks +3 more
2008Cell Cycle69 citations Open access
Semantic Scholar
Hypoxia: a double-edged sword of immunity
A. Sica, G. Melillo, L. Varesio
2011Journal of molecular medicine64 citations
Semantic Scholar
Hypoxia Predicts Poor Prognosis in Neuroblastoma Patients and Associates with Biological Mechanisms Involved in Telomerase Activation and Tumor Microenvironment Reprogramming
Davide Cangelosi, Martina Morini, Nicolò Zanardi, A. Sementa +7 more
2020Cancers59 citations Open access
Semantic Scholar
The human amniotic fluid stem cell secretome effectively counteracts doxorubicin-induced cardiotoxicity
E. Lazzarini, C. Balbi, P. Altieri, Ulrich Pfeffer +10 more
2016Scientific Reports59 citations Open access
Semantic Scholar
Chronic hypoxia reprograms human immature dendritic cells by inducing a proinflammatory phenotype and TREM‐1 expression
D. Pierobon, M. C. Bosco, F. Blengio, Federica Raggi +7 more
2013European Journal of Immunology55 citations Open access
Semantic Scholar
Hypoxia transcriptionally induces macrophage‐inflammatory protein‐3α/CCL‐20 in primary human mononuclear phagocytes through nuclear factor (NF)‐κB
F. Battaglia, S. Delfino, E. Merello, M. Puppo +3 more
200851 citations
Semantic Scholar
Exosomal microRNAs from Longitudinal Liquid Biopsies for the Prediction of Response to Induction Chemotherapy in High-Risk Neuroblastoma Patients: A Proof of Concept SIOPEN Study ‖
Martina Morini, Davide Cangelosi, Daniela Segalerba, D. Marimpietri +21 more
2019Cancers50 citations Open access
Semantic Scholar
Hypoxic synovial environment and expression of macrophage inflammatory protein 3gamma/CCL20 in juvenile idiopathic arthritis.
M. C. Bosco, S. Delfino, F. Ferlito, F. Battaglia +6 more
2008Arthritis & Rheumatism49 citations
Semantic Scholar
Therapeutic Potential of Targeting TREM-1 in Inflammatory Diseases and Cancer.
M. C. Bosco, Federica Raggi, L. Varesio
2016Current pharmaceutical design42 citations
Semantic Scholar
The Hypoxic Synovial Environment Regulates Expression of Vascular Endothelial Growth Factor and Osteopontin in Juvenile Idiopathic Arthritis
M. C. Bosco, S. Delfino, F. Ferlito, M. Puppo +5 more
2009Journal of Rheumatology42 citations Open access
Semantic Scholar
Heterogeneous MYCN amplification in neuroblastoma: a SIOP Europe Neuroblastoma Study
Ana P. Berbegall, D. Bogen, U. Pötschger, K. Beiske +20 more
2018British Journal of Cancer40 citations Open access
Semantic Scholar
Dendritic cell reprogramming by the hypoxic environment.
M. C. Bosco, L. Varesio
2012Immunobiology36 citations Open access
Semantic Scholar
Artificial neural network classifier predicts neuroblastoma patients’ outcome
Davide Cangelosi, Simone Pelassa, Martina Morini, M. Conte +4 more
2016BMC Bioinformatics35 citations Open access
Semantic Scholar
The l1-l2 regularization framework unmasks the hypoxia signature hidden in the transcriptome of a set of heterogeneous neuroblastoma cell lines
Paolo Fardin, A. Barla, S. Mosci, L. Rosasco +2 more
2009BMC Genomics33 citations Open access
Semantic Scholar
Logic Learning Machine creates explicit and stable rules stratifying neuroblastoma patients
Davide Cangelosi, F. Blengio, R. Versteeg, A. Eggert +6 more
2013BMC Bioinformatics32 citations Open access
Semantic Scholar
Hypoxia transcriptionally induces macrophage-inflammatory protein-3alpha/CCL-20 in primary human mononuclear phagocytes through nuclear factor (NF)-kappaB.
F. Battaglia, S. Delfino, E. Merello, M. Puppo +3 more
2008Journal of Leukocyte Biology32 citations
Semantic Scholar
CHL1 gene acts as a tumor suppressor in human neuroblastoma
M. Ognibene, G. Pagnan, D. Marimpietri, Davide Cangelosi +9 more
2018OncoTarget31 citations Open access
Semantic Scholar
Use of Attribute Driven Incremental Discretization and Logic Learning Machine to build a prognostic classifier for neuroblastoma patients
Davide Cangelosi, M. Muselli, S. Parodi, F. Blengio +4 more
2014BMC Bioinformatics29 citations Open access
Semantic Scholar
Development of hepatocellular adenomas and carcinomas in mice with liver-specific G6Pase-α deficiency
Roberta Resaz, Cristina Vanni, Daniela Segalerba, A. Sementa +8 more
2014Disease Models & Mechanisms26 citations Open access
Semantic Scholar
Early response of gene clusters is associated with mouse lung resistance or sensitivity to cigarette smoke.
E. Cavarra, Paolo Fardin, S. Fineschi, A. Ricciardi +7 more
2009American Journal of Physiology - Lung cellular and Molecular Physiology25 citations
Semantic Scholar
The SRCIN1/p140Cap adaptor protein negatively regulates the aggressiveness of neuroblastoma
Silvia Grasso, Davide Cangelosi, J. Chapelle, M. Alzona +20 more
2019Cell Death and Differentiation24 citations Open access
Semantic Scholar
The p53 codon 72 Pro/Pro genotype identifies poor-prognosis neuroblastoma patients: correlation with reduced apoptosis and enhanced senescence by the p53-72P isoform.
S. Cattelani, G. Ferrari‐Amorotti, Sara Galavotti, R. Defferrari +19 more
2012Neoplasia22 citations Open access
Semantic Scholar
Design of a multi-signature ensemble classifier predicting neuroblastoma patients' outcome
Andrea Cornero, M. Acquaviva, Paolo Fardin, R. Versteeg +6 more
2012BMC Bioinformatics21 citations Open access
Semantic Scholar
Identification of CD300a as a new hypoxia-inducible gene and a regulator of CCL20 and VEGF production by human monocytes and macrophages
Federica Raggi, F. Blengio, A. Eva, D. Pende +2 more
2014Innate Immunity20 citations Open access
Semantic Scholar
Normalization of low-density microarray using external spike-in controls: analysis of macrophage cell lines expression profile
Paolo Fardin, S. Moretti, B. Biasotti, A. Ricciardi +2 more
2007BMC Genomics19 citations Open access
Semantic Scholar
A digital repository with an extensible data model for biobanking and genomic analysis management
Massimiliano Izzo, Francesco Mortola, G. Arnulfo, M. Fato +1 more
2014BMC Genomics17 citations Open access
Semantic Scholar
Spermine metabolism and radiation-derived reactive oxygen species for future therapeutic implications in cancer: an additive or adaptive response
R. Amendola, M. Cervelli, G. Tempera, E. Fratini +3 more
2014Amino Acids17 citations
Semantic Scholar
The Tumor Suppressor Hamartin Enhances Dbl Protein Transforming Activity through Interaction with Ezrin*
M. Ognibene, Cristina Vanni, Daniela Segalerba, P. Mancini +5 more
2011Journal of Biological Chemistry16 citations Open access
Semantic Scholar
Transcriptome analysis defines myocardium gene signatures in children with ToF and ASD and reveals disease-specific molecular reprogramming in response to surgery with cardiopulmonary bypass
Federica Raggi, Davide Cangelosi, P. Becherini, F. Blengio +8 more
2020Journal of Translational Medicine15 citations Open access
Semantic Scholar
A PROTEOMIC ANALYSIS OF GSD-1a IN MOUSE LIVERS: EVIDENCE FOR METABOLIC REPROGRAMMING, INFLAMMATION AND MACROPHAGE POLARIZATION.
Davide Cangelosi, Roberta Resaz, A. Petretto, Daniela Segalerba +9 more
2019Journal of Proteome Research15 citations
Semantic Scholar
Macrophage-inflammatory protein-3alpha/CCL-20 is transcriptionally induced by the iron chelator desferrioxamine in human mononuclear phagocytes through nuclear factor (NF)-kappaB.
L. Varesio, F. Battaglia, Federica Raggi, B. Ledda +1 more
2010Molecular Immunology15 citations
Semantic Scholar
Event‐free survival of infants and toddlers enrolled in the HR‐NBL‐1/SIOPEN trial is associated with the level of neuroblastoma mRNAs at diagnosis
M. Corrias, S. Parodi, A. Tchirkov, T. Lammens +13 more
2018Pediatric Blood & Cancer14 citations Open access
Semantic Scholar
Immunohistochemical analysis of PDK1, PHD3 and HIF-1α expression defines the hypoxic status of neuroblastoma tumors
M. Ognibene, Davide Cangelosi, Martina Morini, Daniela Segalerba +4 more
2017PLoS ONE14 citations Open access
Semantic Scholar

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Federica Raggi×12
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