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F. Penco · SciRah

Researcher profile · Semantic Scholar

F. Penco

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F. Penco — researcher profile on SciRah

h-index: 18
Works: 50
Citations: 1,689

Most-cited papers

Regulation of Human Macrophage M1–M2 Polarization Balance by Hypoxia and the Triggering Receptor Expressed on Myeloid Cells-1
Federica Raggi, Simone Pelassa, D. Pierobon, F. Penco +6 more
2017Frontiers in Immunology261 citations Open access
Semantic Scholar
ADA2 deficiency (DADA2) as an unrecognised cause of early onset polyarteritis nodosa and stroke: a multicentre national study
R. Caorsi, F. Penco, A. Grossi, A. Insalaco +27 more
2017Annals of the Rheumatic Diseases229 citations Open access
Semantic Scholar
Role of IL-1 Beta in the Development of Human TH17 Cells: Lesson from NLPR3 Mutated Patients
D. Lasiglié, E. Traggiai, S. Federici, M. Alessio +6 more
2011PLoS ONE131 citations Open access
Semantic Scholar
An Update on Familial Mediterranean Fever
M. Lancieri, M. Bustaffa, S. Palmeri, I. Prigione +5 more
2023International Journal of Molecular Sciences120 citations Open access
Semantic Scholar
Monogenic polyarteritis: the lesson of ADA2 deficiency
R. Caorsi, F. Penco, F. Schena, M. Gattorno
2016Pediatric Rheumatology Online Journal120 citations Open access
Semantic Scholar
Cell stress increases ATP release in NLRP3 inflammasome-mediated autoinflammatory diseases, resulting in cytokine imbalance
S. Carta, F. Penco, Rosa Lavieri, A. Martini +3 more
2015Proceedings of the National Academy of Sciences of the United States of America116 citations Open access
Semantic Scholar
Dependence of immunoglobulin class switch recombination in B cells on vesicular release of ATP and CD73 ectonucleotidase activity.
F. Schena, Stefano Volpi, Caterina Elisa Faliti, F. Penco +20 more
2013Cell Reports85 citations Open access
Semantic Scholar
Actin Remodeling Defects Leading to Autoinflammation and Immune Dysregulation
R. Papa, F. Penco, Stefano Volpi, M. Gattorno
2021Frontiers in Immunology70 citations Open access
Semantic Scholar
Syndrome of Undifferentiated Recurrent Fever (SURF): An Emerging Group of Autoinflammatory Recurrent Fevers
R. Papa, F. Penco, Stefano Volpi, D. Sutera +2 more
2021Journal of Clinical Medicine63 citations Open access
Semantic Scholar
Disease activity accounts for long-term efficacy of IL-1 blockers in pyogenic sterile arthritis pyoderma gangrenosum and severe acne syndrome.
A. Omenetti, S. Carta, R. Caorsi, M. Finetti +10 more
2016Rheumatology48 citations
Semantic Scholar
Adenosine Deaminase 2 Deficiency (DADA2): A Crosstalk Between Innate and Adaptive Immunity
S. Signa, A. Bertoni, F. Penco, R. Caorsi +5 more
2022Frontiers in Immunology45 citations Open access
Semantic Scholar
HLA-G and HLA-E in patients with juvenile idiopathic arthritis.
I. Prigione, F. Penco, A. Martini, M. Gattorno +2 more
2011Rheumatology43 citations Open access
Semantic Scholar
Spontaneous NLRP3 inflammasome-driven IL-1-β secretion is induced in severe COVID-19 patients and responds to anakinra treatment
A. Bertoni, F. Penco, Hilaria Mollica, P. Bocca +20 more
2022Journal of Allergy and Clinical Immunology41 citations Open access
Semantic Scholar
Cryopyrin-associated Periodic Syndromes in Italian Patients: Evaluation of the Rate of Somatic NLRP3 Mosaicism and Phenotypic Characterization
D. Lasiglié, A. Mensa-Vilaró, Denise Ferrera, R. Caorsi +23 more
2017Journal of Rheumatology36 citations Open access
Semantic Scholar
Clinical Characteristics of Patients Carrying the Q703K Variant of the NLRP3 Gene: A 10-year Multicentric National Study
A. Naselli, F. Penco, L. Cantarini, A. Insalaco +14 more
2016Journal of Rheumatology36 citations Open access
Semantic Scholar
Clinical characterization, long-term follow-up, and response to treatment of patients with syndrome of undifferentiated recurrent fever (SURF).
D. Sutera, M. Bustaffa, R. Papa, C. Matucci-Cerinic +9 more
2022Seminars in Arthritis & Rheumatism32 citations
Semantic Scholar
Dysregulation in B‐cell responses and T follicular helper cell function in ADA2 deficiency patients
F. Schena, F. Penco, Stefano Volpi, Claudia Pastorino +17 more
2020European Journal of Immunology32 citations Open access
Semantic Scholar
Complex regulation of alarmins S100A8/A9 and secretion via Gasdermin-D pores exacerbates autoinflammation in Familial Mediterranean Fever.
Selina K. Jorch, A. McNally, P. Berger, Jonas Wolf +22 more
2023Journal of Allergy and Clinical Immunology23 citations Open access
Semantic Scholar
Case Report: Deficiency of Adenosine Deaminase 2 Presenting With Overlapping Features of Autoimmune Lymphoproliferative Syndrome and Bone Marrow Failure
G. Dell'Orso, A. Grossi, F. Penco, R. Caorsi +12 more
2021Frontiers in Immunology18 citations Open access
Semantic Scholar
Two siblings presenting with novel ADA2 variants, lymphoproliferation, persistence of large granular lymphocytes, and T-cell perturbations.
Francesco Saettini, G. Fazio, Paola Corti, M. Quadri +16 more
2020Clinical Immunology18 citations
Semantic Scholar
Long-term efficacy of MAS825, a bispecific anti-IL1β and IL-18 monoclonal antibody, in two patients with systemic JIA and recurrent episodes of macrophage activation syndrome
R. Caorsi, A. Bertoni, C. Matucci-Cerinic, Valentina Natoli +11 more
2024Rheumatology17 citations Open access
Semantic Scholar
A novel knock-in mouse model of CAPS that develops amyloidosis: therapeutic efficacy of proton pump inhibitors.
A. Bertoni, S. Carta, C. Baldovini, F. Penco +16 more
2020Journal of Allergy and Clinical Immunology15 citations Open access
Semantic Scholar
Pyrin Inflammasome Activation Defines Colchicine-Responsive SURF Patients from FMF and Other Recurrent Fevers
S. Palmeri, F. Penco, A. Bertoni, M. Bustaffa +11 more
2024Journal of Clinical Immunology14 citations
Semantic Scholar
ADA2 deficiency due to a novel structural variation in 22q11.1
A. Grossi, R. Cusano, M. Rusmini, F. Penco +6 more
2019Clinical Genetics13 citations
Semantic Scholar
Case Report: Susceptibility to viral infections and secondary hemophagocytic lymphohistiocytosis responsive to intravenous immunoglobulin as primary manifestations of adenosine deaminase 2 deficiency
Enrico Drago, F. Garbarino, S. Signa, A. Grossi +8 more
2022Frontiers in Immunology12 citations Open access
Semantic Scholar
A Novel LC–MS/MS-Based Method for the Diagnosis of ADA2 Deficiency from Dried Plasma Spot
A. Cafaro, Federica Pigliasco, S. Barco, F. Penco +6 more
2021Molecules12 citations Open access
Semantic Scholar
Dysregulation of miRNA-30e-3p targeting IL-1β in an international cohort of systemic autoinflammatory disease patients
T. H. Akbaba, Yeliz Z. Akkaya-Ulum, E. Batu, F. Penco +7 more
2023Journal of molecular medicine10 citations Open access
Semantic Scholar
Knowledge, practices, educational needs and hospital engagement in Infection Prevention and Control (IPC) among Italian healthcare workers and students: results from a national multicentre survey
F. Di Gennaro, F. Segala, Roberta Papagni, Elda De Vita +17 more
2025JAC-Antimicrobial Resistance9 citations Open access
Semantic Scholar
Case Report: Consistent disease manifestations with a staggered time course in two identical twins affected by adenosine deaminase 2 deficiency
F. Barzaghi, M. Cicalese, M. Zoccolillo, I. Brigida +31 more
2022Frontiers in Immunology6 citations Open access
Semantic Scholar
Abstracts from the ISSAID 2021 Periodic Congress
A. Bertoni, F. Penco, H. Mollica, P. Bocca +16 more
2022Pediatric Rheumatology Online Journal5 citations Open access
Semantic Scholar
Proteomic Signatures of Monocytes in Hereditary Recurrent Fevers
F. Penco, A. Petretto, C. Lavarello, R. Papa +7 more
2022Frontiers in Immunology4 citations Open access
Semantic Scholar
Predictive factors for therapeutic response and cluster analysis in syndrome of undifferentiated recurrent fever (SURF)
S. Palmeri, M. Ponzano, Giada Recchi, C. Conti +12 more
2025RMD Open3 citations Open access
Semantic Scholar
Redox imbalance and NLRP3 activation: H Syndrome mistaken for CAPS-a case report.
S. Palmeri, Anna Agrusti, Valentina Natoli, S. Orsi +11 more
2025Rheumatology2 citations
Semantic Scholar
Inborn Error of WAS Presenting with SARS-CoV-2-Related Multisystem Inflammatory Syndrome in Children
Enrico Drago, F. Fioredda, F. Penco, I. Prigione +10 more
2024Journal of Clinical Immunology2 citations Open access
Semantic Scholar
Corrigendum to "Clinical characterization, long-term follow-up, and response to treatment of patients with syndrome of undifferentiated recurrent fever (SURF)" Seminars in Arthritis and Rheumatism 55 (2022) 152024.
D. Sutera, M. Bustaffa, R. Papa, C. Matucci-Cerinic +9 more
2023Seminars in Arthritis & Rheumatism2 citations Open access
Semantic Scholar
Bespoke Base and Prime Editing Approaches for STING-Associated Vasculopathy with Onset in Infancy (SAVI)
Enrico Drago, Jona Papri, Chiara Fresia, G. Casirati +16 more
2026Journal of Human Immunity1 citations Open access
Semantic Scholar
Household and community-based approaches to malaria and cholera prevention: A narrative review with case studies from Uganda and Mozambique
G. Guido, Valentina Totaro, P. Lochoro, Jerry Ictho +16 more
2026PLoS Neglected Tropical Diseases1 citations Open access
Semantic Scholar
Neurological Phenotypes of SOCS1 Haploinsufficiency: Insights from Functional and Histological Investigations
S. Palmeri, I. Prigione, F. Schena, M. Jeanpierre +18 more
2025Journal of Clinical Immunology1 citations Open access
Semantic Scholar
How multi-omic technologies can help define paediatric undifferentiated systemic autoinflammatory diseases: the experience of the European PerSAIDs consortium
Camilla Speziani, S. Palmeri, P. Uva, Simona Gattulli +17 more
2026RMD Open0 citations Open access
Semantic Scholar
Case Report: Sirolimus as management strategy for thrombocytopenia related to ARPC1B deficiency
Gianluca Dellorso, Martina Guardigni, E. Palmisani, Enrico Drago +11 more
2026Frontiers in Immunology0 citations Open access
Semantic Scholar
Long-Term Viral Presence in Monocytes Correlates with Dysregulation of Innate Immunity in Patients with SARS-CoV-2–Related Multisystem Inflammatory Syndrome in Children
Enrico Drago, I. Prigione, A. Bertoni, F. Penco +13 more
2025Journal of Human Immunity0 citations Open access
Semantic Scholar
THU0509 MONOCYTES PROTEOMIC PROFILE OF PATIENTS WITH DIFFERENT AUTOINFLAMMATORY DISEASES: A NEW APPROACH TO CHARACTERIZE THESE DISEASES
F. Penco, Andrea Petetto, C. Lavarello, I. Gueli +4 more
2019Poster Presentations0 citations Open access
Semantic Scholar
THU0505 INTRINSIC AND EXTRINSIC B CELL DEFECT IN DADA2 PATIENTS
F. Schena, F. Penco, Stefano Volpi, Claudia Pastorino +16 more
2019Poster Presentations0 citations Open access
Semantic Scholar
Author response for "ADA2 deficiency due to a novel structural variation in 22q11.1"
A. Grossi, R. Cusano, M. Rusmini, F. Penco +6 more
20190 citations
Semantic Scholar
OP0106 A NOVEL KNOCK-IN MOUSE MODEL OF CAPS THAT DEVELOPS AMYLOIDOSIS: THERAPEUTIC EFFICACY OF PROTON PUMP INHIBITORS
A. Bertoni, S. Carta, C. Baldovini, F. Penco +15 more
2019Oral Presentations0 citations Open access
Semantic Scholar
iCARE: Telematic Platform for the Improvement of Home Care Services for Pediatric Palliative Care
L. Bianconi, C. Degano, Matteo Toma, L. Manfredini +4 more
2016International Conference on eHealth, Telemedicine, and Social Medicine0 citations
Semantic Scholar
Recruitment of abundant NK cells to the PFAPA tonsils support the crucial role of innate immunity in pathogenesis of PFAPA syndrome
S. Chiesa, R. Caorsi, I. Ingrosso, F. Bellora +10 more
2015Pediatric Rheumatology Online Journal0 citations Open access
Semantic Scholar
Cryopyrin associated periodic syndromes (CAPS): immunological characterization of knock-in mouse model to exploit novel approaches for the modulation of the NLRP3 inflammasome.
A. Bertoni, S. Carta, E. Balza, P. Catellani +11 more
2015Pediatric Rheumatology Online Journal0 citations Open access
Semantic Scholar
Rheumatoid arthritis and other inflammatory joint diseases (human studies) (WS-036) Chairpersons: Tsutomu Takeuchi, Nobuyuki Miyasaka
M. Bokarewa, E. Boström, M. Svensson, S. Andersson +39 more
20100 citations
Semantic Scholar
WSC 20 ‐ Immunological Kidney Diseases and Periodic Fever Syndromes
V. Chernyshov, I. Sudoma, B. Donskoi, A. Kostyuchyk +42 more
20090 citations Open access
Semantic Scholar

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