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I. van der Heijden · SciRah

Researcher profile · Semantic Scholar

I. van der Heijden

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I. van der Heijden — researcher profile on SciRah

h-index: 14
Works: 32
Citations: 2,013

Most-cited papers

Loss of p53 triggers Wnt-dependent systemic inflammation to drive breast cancer metastasis
M. Wellenstein, S. Coffelt, D. Duits, M. V. van Miltenburg +16 more
2019Nature435 citations Open access
Semantic Scholar
Selective induction of chemotherapy resistance of mammary tumors in a conditional mouse model for hereditary breast cancer
S. Rottenberg, A. Nygren, M. Pajic, F. V. van Leeuwen +9 more
2007Proceedings of the National Academy of Sciences of the United States of America326 citations Open access
Semantic Scholar
BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance.
R. Drost, P. Bouwman, S. Rottenberg, U. Boon +12 more
2011Cancer Cell269 citations Open access
Semantic Scholar
The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin
Yi-Fan Wang, Andrea J. Bernhardy, C. Cruz, J. Krais +34 more
2016Cancer Research263 citations Open access
Semantic Scholar
A high-throughput functional complementation assay for classification of BRCA1 missense variants.
P. Bouwman, H. van der Gulden, I. van der Heijden, R. Drost +7 more
2013Cancer Discovery139 citations
Semantic Scholar
The human multidrug resistance protein MRP5 transports folates and can mediate cellular resistance against antifolates.
P. Wielinga, J. H. Hooijberg, Sjofn Gunnarsdottir, I. Kathmann +10 more
2005Cancer Research135 citations Open access
Semantic Scholar
BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1.
R. Drost, Kiranjit K. Dhillon, H. van der Gulden, I. van der Heijden +25 more
2016Journal of Clinical Investigation131 citations Open access
Semantic Scholar
Loss of nuclear DNA ligase III reverts PARP inhibitor resistance in BRCA1/53BP1 double-deficient cells by exposing ssDNA gaps
M. Dias, V. Tripathi, I. van der Heijden, Ke Cong +17 more
2021bioRxiv90 citations Open access
Semantic Scholar
cGMP transport by vesicles from human and mouse erythrocytes
C. D. de Wolf, Hiroaki Yamaguchi, I. van der Heijden, P. Wielinga +7 more
2007The FEBS Journal79 citations
Semantic Scholar
Comprehensive characterization of pre- and post-treatment samples of breast cancer reveal potential mechanisms of chemotherapy resistance
M. Hoogstraat, E. Lips, I. Mayayo-Peralta, L. Mulder +9 more
2022npj Breast Cancer37 citations Open access
Semantic Scholar
Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors
J. Bhin, Mariana Paes Dias, E. Gogola, F. Rolfs +18 more
2023Cell Reports34 citations Open access
Semantic Scholar
Functional Categorization of BRCA1 Variants of Uncertain Clinical Significance in Homologous Recombination Repair Complementation Assays
P. Bouwman, I. van der Heijden, H. van der Gulden, Roebi de Bruijn +25 more
2020Clinical Cancer Research29 citations Open access
Semantic Scholar
NASP modulates histone turnover to drive PARP inhibitor resistance
S. Moser, Anna Khalizieva, Josef Roehsner, Elisabeth Pottendorfer +25 more
2025Nature22 citations Open access
Semantic Scholar
BRCA 1 185 delAG tumors may acquire therapy resistance through expression of RINGless BRCA 1
R. Drost, Kiranjit K. Dhillon, H. van der Gulden, I. van der Heijden +25 more
201816 citations
Semantic Scholar
Response of metastatic mouse invasive lobular carcinoma to mTOR inhibition is partly mediated by the adaptive immune system
S. Klarenbeek, C. Doornebal, S. Kas, Nicola Bonzanni +12 more
2020Oncoimmunology11 citations Open access
Semantic Scholar
Loss of Nuclear DNA ligase III Can Revert PARP Inhibitor Resistance in BRCA 1-deficient 1 Cells by Increasing DNA Replication Stress 2
M. Dias, V. Tripathi, I. van der Heijden, Cong Ke +17 more
20211 citations
Semantic Scholar
Loss of Nuclear DNA Ligase III Reverts PARP Inhibitor Resistance in BRCA1-Deficient Cells by Increasing DNA Replication Stress
Mariana Paes Dias, V. Tripathi, I. van der Heijden, Ke Cong +15 more
2020Social Science Research Network1 citations
Semantic Scholar
FIRRM/C1orf112 mediates resolution of homologous recombination intermediates in response to DNA interstrand crosslinks
A. Mazouzi, S. Moser, F. Abascal, B. van den Broek +10 more
2023Science Advances0 citations Open access
Semantic Scholar
Comprehensive characterization of pre- and post-treatment samples of breast cancer reveal potential mechanisms of chemotherapy resistance
M. Hoogstraat, E. Lips, I. Mayayo-Peralta, L. Mulder +9 more
2022npj Breast Cancer0 citations Open access
Semantic Scholar
Correction: Functional Categorization of BRCA1 Variants of Uncertain Clinical Significance in Homologous Recombination Repair Complementation Assays.
P. Bouwman, I. van der Heijden, H. van der Gulden, Roebi de Bruijn +5 more
2022Clinical Cancer Research0 citations
Semantic Scholar
Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors
J. Bhin, M. Dias, E. Gogola, F. Rolfs +17 more
2022bioRxiv0 citations Open access
Semantic Scholar
Ethical Considerations for Conducting Research on Violence against Women with Disabilities: Discussing Issues of Reasonable Accommodation, Capacity and Equal Participation
I. van der Heijden, N. Abrahams, J. Harries
20170 citations
Semantic Scholar
'It Is a Sin to Be in Love with a Disabled Woman': Stigma, Rejection and Intersections of Womanhood and Violence among Physically Disabled Women Living in South Africa
I. van der Heijden, N. Abrahams, J. Harries
20170 citations
Semantic Scholar
Kunstenaarslevens in woord en beeld : Prentenboeken over Gustave Caillebotte en Karel Appel
H. Debrauwer, I. van der Heijden
20170 citations
Semantic Scholar
Bindende banden versterken of overbruggende banden creëren?Pedagogische Civil Society en interetnisch contact in Culemborg
P. Abrol, F. Bolwijn, I. van der Heijden, S. Maas
20160 citations
Semantic Scholar
Boosting Entrepreneurship In South Eastern Europe - International Political Economy
I. van der Heijden
20150 citations
Semantic Scholar
PI3K signalling in mouse models of invasive lobular breast cancer
S. Klarenbeek, C. Doornebal, Nicola Bonzanni, S. Kas +5 more
20150 citations
Semantic Scholar
Production and pharmaceutical formulation of plasmid DNA vaccines
I. van der Heijden
20130 citations
Semantic Scholar
Histidine enhances transfection efficiency in vitro and ex vivo of poly ( amidoamine ) s polyplexes for intradermal DNA tattoo vaccination
I. van der Heijden, M. de Raad, W. Hennink, J. Engbersen +3 more
20130 citations
Semantic Scholar
Reply to Dr Damjanovic et al.: ‘Is the endogenous pathogenesis of Candida parapsilosis infection underreported?’
L. Miranda, I. van der Heijden, S. Costa, R. D. Lobo +1 more
20100 citations
Semantic Scholar
Abstract 2140: Finding co-occurrence and mutual exclusiveness in DNA copy number data
C. Klijn, J. Bot, S. Klarenbeek, I. van der Heijden +4 more
20100 citations
Semantic Scholar
Towards targeted screening for drugs active against lobular breast carcinoma
M. de Bruin, Tanya M. Braumuller, I. van der Heijden, Hermien Boerhout +4 more
20080 citations
Semantic Scholar

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