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D. Landau · SciRah

Researcher profile · Semantic Scholar

D. Landau

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D. Landau — researcher profile on SciRah

h-index: 40
Works: 145
Citations: 11K

Most-cited papers

Mutations driving CLL and their evolution in progression and relapse
D. Landau, E. Tausch, Amaro Taylor-Weiner, Chip Stewart +27 more
2015Nature1,037 citations Open access
Semantic Scholar
Resistance to checkpoint blockade therapy through inactivation of antigen presentation
M. Sade-Feldman, Yunxin J. Jiao, Jonathan H. Chen, Michael S. Rooney +27 more
2017Nature Communications898 citations Open access
Semantic Scholar
Discovery of a periosteal stem cell mediating intramembranous bone formation
Shawon Debnath, Alisha R. Yallowitz, J. McCormick, Sarfaraz Lalani +12 more
2018Nature616 citations Open access
Semantic Scholar
Genomic complexity of multiple myeloma and its clinical implications
S. Manier, K. Salem, Jihye Park, D. Landau +2 more
2017Nature Reviews Clinical Oncology520 citations
Semantic Scholar
Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring
Asaf Zviran, Rafael C. Schulman, M. Shah, S. T. Hill +38 more
2020Nature Medicine373 citations Open access
Semantic Scholar
Integrating genetic and non-genetic determinants of cancer evolution by single-cell multi-omics
Anna S. Nam, R. Chaligné, D. Landau
2020Nature reviews genetics337 citations Open access
Semantic Scholar
Genotyping of Transcriptomes links somatic mutations and cell identity
Anna S. Nam, Kyu-Tae Kim, R. Chaligné, Franco Izzo +20 more
2019Nature236 citations Open access
Semantic Scholar
Epigenetic evolution and lineage histories of chronic lymphocytic leukemia
Federico Gaiti, R. Chaligné, H. Gu, Ryan Brand +22 more
2019Nature235 citations Open access
Semantic Scholar
Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states
R. Chaligné, Federico Gaiti, Dana Silverbush, Joshua S. Schiffman +17 more
2021Nature Genetics204 citations Open access
Semantic Scholar
DNA methylation disruption reshapes the hematopoietic differentiation landscape
Franco Izzo, S. Lee, A. Poran, R. Chaligné +18 more
2020Nature Genetics202 citations Open access
Semantic Scholar
Transcriptomic characterization of SF3B1 mutation reveals its pleiotropic effects in chronic lymphocytic leukemia
Li-Li Wang, A. Brooks, Jean Fan, Youzhong Wan +31 more
2016Cancer Cell200 citations Open access
Semantic Scholar
Integrated protein and transcriptome spatial profiling
N. Ben-Chetrit, Xiang Niu, Ariel D. Swett, Jesus Sotelo +7 more
2023Nature Biotechnology168 citations Open access
Semantic Scholar
m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment
Yuanming Cheng, Hanzhi Luo, Franco Izzo, B. Pickering +9 more
2019Cell Reports160 citations Open access
Semantic Scholar
The evolutionary landscape of chronic lymphocytic leukemia treated with ibrutinib targeted therapy
D. Landau, Clare Sun, D. Rosebrock, Sarah E. M. Herman +18 more
2017Nature Communications157 citations Open access
Semantic Scholar
Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition
S. Hogg, Olga Motorna, L. Cluse, Timothy M. Johanson +38 more
2021Molecules and Cells156 citations Open access
Semantic Scholar
Chromosomal Instability as a Driver of Tumor Heterogeneity and Evolution.
S. Bakhoum, D. Landau
2017Cold Spring Harbor Perspectives in Medicine142 citations Open access
Semantic Scholar
Single-cell multi-omics of human clonal hematopoiesis reveals that DNMT3A R882 mutations perturb early progenitor states through selective hypomethylation
Anna S. Nam, N. Dusaj, Franco Izzo, Rekha R. Murali +13 more
2022bioRxiv118 citations Open access
Semantic Scholar
Epigenetic dysregulation from chromosomal transit in micronuclei
Albert S. Agustinus, Duaa H. Al-Rawi, Bhargavi Dameracharla, R. Raviram +28 more
2022bioRxiv108 citations Open access
Semantic Scholar
DeTiN : Overcoming Tumor in Normal Contamination
Amaro Taylor-Weiner, Chip Stewart, T. Giordano, Mendy Miller +7 more
2018Nature Methods78 citations Open access
Semantic Scholar
Corrupted coordination of epigenetic modifications leads to diverging chromatin states and transcriptional heterogeneity in CLL
A. Pastore, Federico Gaiti, Sydney X. Lu, Ryan Brand +19 more
2019Nature Communications76 citations Open access
Semantic Scholar
Nanobody-tethered transposition enables multifactorial chromatin profiling at single-cell resolution
T. Stuart, S. Hao, Bingjie Zhang, Levan Mekerishvili +4 more
2022Nature Biotechnology73 citations Open access
Semantic Scholar
Specification of fetal liver endothelial progenitors to functional zonated adult sinusoids requires c-Maf induction
J. Gómez-Salinero, Franco Izzo, Yang Lin, S. Houghton +14 more
2022Cell Stem Cell59 citations Open access
Semantic Scholar
Discovery of candidate DNA methylation cancer driver genes
H. Pan, L. Renaud, R. Chaligné, J. Bloehdorn +15 more
2021Cancer Discovery59 citations Open access
Semantic Scholar
Cancer Evolution: A Multifaceted Affair
G. Ciriello, Luca Magnani, Sarah J. Aitken, L. Akkari +16 more
2023Cancer Discovery58 citations Open access
Semantic Scholar
Single-cell multi-omics defines the cell-type specific impact of splicing aberrations in human hematopoietic clonal outgrowths
M. Cortés-López, P. Chamely, Allegra G. Hawkins, Robert F. Stanley +30 more
2022bioRxiv57 citations Open access
Semantic Scholar
Smart-RRBS for single-cell methylome and transcriptome analysis
H. Gu, Ayush T. Raman, Xiao-Xue Wang, Federico Gaiti +8 more
2021Nature Protocols56 citations Open access
Semantic Scholar
Acute Myeloid Leukemia iPSCs Reveal a Role for RUNX1 in the Maintenance of Human Leukemia Stem Cells
Josephine Wesely, A. Kotini, Franco Izzo, Hanzhi Luo +11 more
2020Cell Reports45 citations Open access
Semantic Scholar
Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription
J. Edelmann, K. Holzmann, E. Tausch, E. A. Saunderson +23 more
2019Haematologica39 citations Open access
Semantic Scholar
Rare Germline Variants in ATM Are Associated with Chronic Lymphocytic Leukemia
Grace Tiao, M. R. Improgo, Siddha N. Kasar, W. Poh +21 more
2017Leukemia36 citations Open access
Semantic Scholar
EpiMethylTag: simultaneous detection of ATAC-seq or ChIP-seq signals with DNA methylation
Priscillia Lhoumaud, Gunjan Sethia, Franco Izzo, T. Sakellaropoulos +10 more
2019Genome Biology35 citations Open access
Semantic Scholar
Short telomeres are associated with inferior outcome, genomic complexity, and clonal evolution in chronic lymphocytic leukemia
B. Jebaraj, E. Tausch, D. Landau, J. Bahlo +19 more
2019Leukemia32 citations Open access
Semantic Scholar
Jak2V617F Reversible Activation Shows Its Essential Requirement in Myeloproliferative Neoplasms
Andrew Dunbar, Robert L. Bowman, Young C. Park, Kavi O’Connor +30 more
2024Cancer Discovery26 citations Open access
Semantic Scholar
Multi-platform profiling characterizes molecular subgroups and resistance networks in chronic lymphocytic leukemia
J. Bloehdorn, A. Braun, Amaro Taylor-Weiner, B. Jebaraj +30 more
2021Nature Communications22 citations Open access
Semantic Scholar
Leading Edge Previews Cancer Evolution : No Room for Negative Selection
S. Bakhoum, D. Landau
201721 citations
Semantic Scholar
Deep learning mutation prediction enables early stage lung cancer detection in liquid biopsy
S. Kothen-Hill, Asaf Zviran, Rafael C. Schulman, Sunil Deochand +7 more
2018International Conference on Learning Representations20 citations
Semantic Scholar
Genotype-fitness maps of EGFR-mutant lung adenocarcinoma chart the evolutionary landscape of resistance for combination therapy optimization
Patrick J. Bolan, Asaf Zviran, Lisa Brenan, Joshua S. Schiffman +5 more
2019Cell Systems17 citations Open access
Semantic Scholar
SON is an Essential m6A Target for Hematopoietic Stem Cell Fate
Han-Zhi Luo, Mariela Cortés-López, Cyrus L. Tam, Michael Xiao +12 more
2023Cell Stem Cell16 citations Open access
Semantic Scholar
Machine learning guided signal enrichment for ultrasensitive plasma tumor burden monitoring
Adam J. Widman, M. Shah, N. Øgaard, C. Khamnei +38 more
2022bioRxiv14 citations Open access
Semantic Scholar
Integrated Single-Cell Genotyping and Chromatin Accessibility Charts JAK2V617F Human Hematopoietic Differentiation
Robert M. Myers, Franco Izzo, Sanjay V. Kottapalli, Tamara Prieto +16 more
2022bioRxiv13 citations Open access
Semantic Scholar
Integrated protein and transcriptome high-throughput spatial profiling
N. Ben-Chetrit, Xiang Niu, Ariel D. Swett, Jesus Sotelo +4 more
2022bioRxiv12 citations Open access
Semantic Scholar
Defining ancestry, heritability and plasticity of cellular phenotypes in somatic evolution
Joshua S. Schiffman, Andrew R. D'Avino, Tamara Prieto, Ya-Kun Pang +7 more
2023bioRxiv10 citations Open access
Semantic Scholar
Epigenomically Bistable Regions across Neuron-Specific Genes Govern Neuron Eligibility to a Coding Ensemble in the Hippocampus
S. Odell, F. Taki, S. Klein, Rosa J. Chen +13 more
2020Cell Reports10 citations Open access
Semantic Scholar
High throughput droplet single-cell Genotyping of Transcriptomes (GoT) reveals the cell identity dependency of the impact of somatic mutations
Anna S. Nam, Kyu-Tae Kim, R. Chaligné, Franco Izzo +15 more
2018bioRxiv8 citations Open access
Semantic Scholar
Deconvoluting Clonal and Cellular Architecture in IDH-Mutant Acute Myeloid Leukemia
Maria Sirenko, Soobeom Lee, Zhengxi Sun, R. Chaligné +28 more
2023Blood7 citations Open access
Semantic Scholar
A BAX door to venetoclax resistance.
Franco Izzo, D. Landau
2022Blood6 citations
Semantic Scholar
Nanobody-tethered transposition allows for multifactorial chromatin profiling at single-cell resolution
T. Stuart, S. Hao, Bingjie Zhang, Levan Mekerishvili +4 more
2022bioRxiv6 citations Open access
Semantic Scholar
N/KRAS-Mutant AML LSCs Originate from Committed Myelomonocytic Progenitors and Drive Clinical Resistance to Venetoclax
Junya Sango, S. Carcamo, Nataly Cruz-Rodriguez, Maria Sirenko +16 more
2023Blood5 citations
Semantic Scholar
Single-Cell Multi-Omics Defines the Cell-Type Specific Impact of SF3B1 Splicing Factor Mutations on Hematopoietic Differentiation in Human Clonal Hematopoiesis and Myelodysplastic Syndromes
Federico Gaiti, Allegra G. Hawkins, P. Chamely, Ariel D. Swett +17 more
2021Blood5 citations
Semantic Scholar
TARGET-seq Takes Aim at Cancer Evolution through Multi-omics Single-Cell Genotyping and Transcriptomics.
R. Chaligné, Anna S. Nam, D. Landau
2019Molecules and Cells5 citations Open access
Semantic Scholar
Quantitative Clonal Dynamics Define Mechanisms of CLL Evolution in Response to Combination Chemotherapy
D. Landau, E. Tausch, S. Böttcher, Chip Stewart +22 more
20155 citations
Semantic Scholar

Frequent co-authors

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R. Chaligné×16
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R. Chaligné — researcher profile on SciRah
C. Wu×12
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C. Wu — researcher profile on SciRah
Franco Izzo×12
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Franco Izzo — researcher profile on SciRah
Federico Gaiti×10
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Federico Gaiti — researcher profile on SciRah

×9

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O. Abdel-Wahab — researcher profile on SciRah

Robert M. Myers×8

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Robert M. Myers — researcher profile on SciRah

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E. Tausch — researcher profile on SciRah

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K. Fischer — researcher profile on SciRah

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M. Hallek — researcher profile on SciRah

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G. Getz — researcher profile on SciRah

S. Stilgenbauer×7

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S. Stilgenbauer — researcher profile on SciRah

Amaro Taylor-Weiner×6

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Amaro Taylor-Weiner — researcher profile on SciRah