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J. Edelmann · SciRah

Researcher profile · Semantic Scholar

J. Edelmann

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J. Edelmann — researcher profile on SciRah

h-index: 19
Works: 46
Citations: 3,504

Most-cited papers

Mutations driving CLL and their evolution in progression and relapse
D. Landau, E. Tausch, Amaro Taylor-Weiner, Chip Stewart +27 more
2015Nature1,037 citations Open access
Semantic Scholar
TP53 mutation and survival in chronic lymphocytic leukemia.
T. Zenz, B. Eichhorst, R. Busch, T. Denzel +10 more
2010Journal of Clinical Oncology631 citations Open access
Semantic Scholar
Gene mutations and treatment outcome in chronic lymphocytic leukemia: results from the CLL8 trial.
S. Stilgenbauer, A. Schnaiter, P. Paschka, T. Zenz +28 more
2012Blood541 citations
Semantic Scholar
Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up.
T. Zenz, A. Kröber, Katrin Scherer, S. Häbe +8 more
2008Blood433 citations Open access
Semantic Scholar
High-resolution genomic profiling of chronic lymphocytic leukemia reveals new recurrent genomic alterations.
J. Edelmann, K. Holzmann, Florian Miller, D. Winkler +18 more
2012Blood112 citations Open access
Semantic Scholar
NOTCH1, SF3B1, and TP53 mutations in fludarabine-refractory CLL patients treated with alemtuzumab: results from the CLL2H trial of the GCLLSG.
A. Schnaiter, P. Paschka, M. Rossi, T. Zenz +12 more
2012Blood90 citations Open access
Semantic Scholar
Gene expression signatures separate B-cell chronic lymphocytic leukaemia prognostic subgroups defined by ZAP-70 and CD38 expression status
A. Huettmann, Ludger Klein-Hitpass, J. Thomale, R. Deenen +8 more
2006Leukemia90 citations Open access
Semantic Scholar
Genomic disruption of the histone methyltransferase SETD2 in chronic lymphocytic leukemia
H. Parker, M. Rose-Zerilli, Marta Larrayoz, R. Clifford +34 more
2015Leukemia82 citations Open access
Semantic Scholar
High-resolution genomic profiling of adult and pediatric core-binding factor acute myeloid leukemia reveals new recurrent genomic alterations.
Michael W. M. Kühn, I. Radtke, L. Bullinger, S. Goorha +20 more
2010Blood82 citations Open access
Semantic Scholar
Bone marrow fibroblasts induce expression of PI3K/NF-kappaB pathway genes and a pro-angiogenic phenotype in CLL cells.
J. Edelmann, L. Klein-Hitpass, A. Carpinteiro, Anja Führer +4 more
2008Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis76 citations
Semantic Scholar
Treatment resistance in chronic lymphocytic leukemia–the role of the p53 pathway
T. Zenz, J. Mohr, J. Edelmann, A. Sarno +6 more
2009Leukemia and Lymphoma50 citations
Semantic Scholar
Telomere dysfunction and chromothripsis
A. Ernst, David T. W. Jones, K. Maass, A. Rode +21 more
2016International Journal of Cancer48 citations Open access
Semantic Scholar
Genomic alterations in high-risk chronic lymphocytic leukemia frequently affect cell cycle key regulators and NOTCH1-regulated transcription
J. Edelmann, K. Holzmann, E. Tausch, E. A. Saunderson +23 more
2019Haematologica39 citations Open access
Semantic Scholar
Lamin B1 regulates somatic mutations and progression of B-cell malignancies
T. Klymenko, J. Bloehdorn, J. Bahlo, S. Robrecht +13 more
2017Leukemia29 citations Open access
Semantic Scholar
Mutation analysis of the TNFAIP3 (A20) tumor suppressor gene in CLL
C. Philipp, J. Edelmann, A. Bühler, D. Winkler +2 more
2011International Journal of Cancer22 citations
Semantic Scholar
Managing Patients With TP53-Deficient Chronic Lymphocytic Leukemia.
J. Edelmann, J. Gribben
2017Journal of Oncology Practice21 citations
Semantic Scholar
Frequent evolution of copy number alterations in CLL following first-line treatment with FC(R) is enriched with TP53 alterations: Results from the CLL8 trial
J. Edelmann, E. Tausch, Dan A. Landau, S. Robrecht +14 more
2016Leukemia20 citations Open access
Semantic Scholar
Rituximab and obinutuzumab differentially hijack the B cell receptor and NOTCH1 signaling pathways
J. Edelmann, Arran D. Dokal, Emma Vilventhraraja, K. Holzmann +7 more
2021iScience19 citations Open access
Semantic Scholar
Telomere length in poor-risk chronic lymphocytic leukemia: associations with disease characteristics and outcome
Daniela Steinbrecher, B. Jebaraj, C. Schneider, J. Edelmann +11 more
2018Leukemia and Lymphoma19 citations
Semantic Scholar
Genome-wide genotyping of acute myeloid leukemia with translocation t(9;11)(p22;q23) reveals novel recurrent genomic alterations
Michael W. M. Kühn, L. Bullinger, S. Gröschel, J. Krönke +9 more
2014Haematologica11 citations Open access
Semantic Scholar
Obinutuzumab for the treatment of indolent lymphoma.
J. Edelmann, J. Gribben
2016Future Oncology9 citations Open access
Semantic Scholar
Supplementary Table 10
D. Landau, E. Tausch, Amaro Taylor-Weiner, Chip Stewart +27 more
20148 citations
Semantic Scholar
Subclonal Driver Mutations Predict Shorter Progression Free Survival in Chronic Lymphocytic Leukemia Following First-Line Chemo(immuno)Therapy: Results from the CLL8 Trial
D. Landau, E. Tausch, Amaro Taylor-Weiner, S. Böttcher +18 more
20148 citations
Semantic Scholar
Mono-allelic TP53 inactivation is associated with poor prognosis in CLL: Results from a detailed genetic characterization with long term follow-up
T. Zenz, A. Kröber, Katrin Scherer, S. Häbe +8 more
20087 citations
Semantic Scholar
NOTCH1 Signalling: A key pathway for the development of high-risk chronic lymphocytic leukaemia
J. Edelmann
2022Frontiers in Oncology5 citations Open access
Semantic Scholar
Rituximab and Obinutuzumab Induce Direct B-Cell Death Via B-Cell Receptor (BCR) Signaling, but Rituximab Elicits Stronger BCR-Derived Pro-Survival Signals Diminishing Apoptosis
J. Edelmann, Arran D. Dokal, K. Holzmann, D. Britton +7 more
2019Blood4 citations Open access
Semantic Scholar
Telomere Length and Treatment Outcome In Chronic Lymphocytic Leukemia: Results From The CLL8 Trial
B. Jebaraj, R. Busch, T. Zenz, A. Bühler +15 more
20134 citations
Semantic Scholar
Opinion: What defines high-risk CLL in the post-chemoimmunotherapy era?
J. Edelmann, J. Malčíková, J. Riches
2023Frontiers in Oncology3 citations Open access
Semantic Scholar
Reduction of Mitochondrial Membrane Potential Leads to Enhancement of Type-II CD20-Antibody Cytotoxicity in Diffuse Large B-Cell Lymphoma
Emma Vilventhraraja, T. Klymenko, J. Edelmann, J. Gribben +1 more
20162 citations
Semantic Scholar
High-Resolution SNP-Array Profiling of Chronic Lymphocytic Leukemia
J. Edelmann, K. Holzmann, W. M. Michael Kühn, L. Bullinger +9 more
20102 citations
Semantic Scholar
Editorial: Biology and treatment of high-risk CLL
E. Tausch, J. Malčíková, J. Riches, J. Edelmann
2023Frontiers in Oncology1 citations Open access
Semantic Scholar
Anti-CD20 Monoclonal Antibodies Hijack the B-Cell Receptor Signaling Cascade Thereby Activating the NOTCH1 Signaling Pathway
J. Edelmann, D. Britton, Emma Vilventhraraja, Arran D. Dokal +5 more
2018Blood1 citations Open access
Semantic Scholar
High Resolution Genomic Profiling of Primary “Ultra High Risk” and Refractory Chronic Lymphocytic Leukemia: Results from the CLL2O Trial
J. Edelmann, Jenny Saub, S. Ibach, K. Holzmann +11 more
20141 citations
Semantic Scholar
Chromosome Banding and SNP-Array Analysis Are Complementary Methods to Characterize Karyotype Complexity in High-Risk Chronic Lymphocytic Leukemia
J. Edelmann
2023Blood0 citations
Semantic Scholar
(Peri)Centromeric Rearrangements Are Recurrent Recombination Events in Complex-Karyotype Chronic Lymphocytic Leukemia
Maria-Veronica Teleanu, K. Holzmann, J. Edelmann
2022Blood0 citations Open access
Semantic Scholar
Multiplatform Profiling Characterizes Functional Networks in Genomically Stable and Instable Chronic Lymphocytic Leukemia
J. Bloehdorn, A. Braun, B. Jebaraj, Amaro Taylor-Weiner +20 more
2020Blood0 citations Open access
Semantic Scholar
Rituximab Activates NOTCH1 Signaling in CLL Cells and Induces Changes in the Cytokine Repertoire Favoring a Tumor-Protective Microenvironment
J. Edelmann, K. Holzmann, Doriana Di Bella, Emma Vilventhraraja +4 more
20170 citations
Semantic Scholar
Lamin B1 regulates somatic mutation and progression of B cell malignancies
T. Klymenko, J. Bloehdorn, J. Bahlo, S. Robrecht +13 more
20170 citations
Semantic Scholar
In Chronic Lymphocytic Leukemia ΔCT7544-7545 Mutant NOTCH1 Maintains Transcription Factor Activity with Longer Lasting Effects Due to Slower Degradation
J. Edelmann, T. Klymenko, Lu Chen, Emma Vilventhraraja +7 more
20160 citations
Semantic Scholar
High-Resolution Genomic Copy Number Analysis on Sequential Samples from the CLL8 Trial: Relation Between Clonal Evolution and Defects in DNA Damage Response?
J. Edelmann, E. Tausch, J. Bloehdorn, T. Zenz +5 more
20140 citations
Semantic Scholar
Genomic Mechanisms of 17p / TP53 Loss in Primary “ultra High-risk” and Refractory Chronic Lymphocytic Leukemia: Results from the CLL2O Trial
V. Teleanu, J. Edelmann, C. Haferlach, S. Ibach +8 more
20140 citations
Semantic Scholar
GCLLSG patients treated with alemtuzumab : results from the CLL 2 H trial of the mutations in fludarabine-refractory CLL
A. Schnaiter, P. Paschka, M. Rossi, T. Zenz +12 more
20130 citations
Semantic Scholar
acute myeloid leukemia reveals new recurrent genomic alterations High-resolution genomic profiling of adult and pediatric core-binding-factor
J. Rubnitz, J. Downing, R. Ribeiro, V. Gaidzik +12 more
20130 citations
Semantic Scholar
Genome-Wide Genotyping of Acute Myeloid Leukemia with t(9;11) Reveals New Recurrent Genomic Alterations,
Michael W. M. Kühn, L. Bullinger, J. Edelmann, J. Krönke +8 more
20110 citations
Semantic Scholar
IGHV-Mutation Status, IGHV-Gene Usage and Chromosomal Aberrations In CLL: Pooled Analysis within First-Line Clinical Trials of the German CLL Study Group (GCLLSG)
A. Bühler, T. Zenz, D. Winkler, R. Busch +8 more
20100 citations
Semantic Scholar
chronic lymphocytic leukemia : results from a detailed genetic inactivation is associated with poor prognosis in TP 53 Monoallelic
T. Zenz, A. Kröber, Katrin Scherer, S. Häbe +8 more
20080 citations
Semantic Scholar

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J. Gribben — researcher profile on SciRah

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