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E. Meuillet · SciRah

Researcher profile · Semantic Scholar

E. Meuillet

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E. Meuillet — researcher profile on SciRah

h-index: 32
Works: 92
Citations: 3,552

Most-cited papers

A roadmap for interpreting 13C metabolite labeling patterns from cells
J. Buescher, M. Antoniewicz, L. Boros, Shawn C. Burgess +33 more
2015Current Opinion in Biotechnology597 citations Open access
Semantic Scholar
3-(Hydroxymethyl)-bearing phosphatidylinositol ether lipid analogues and carbonate surrogates block PI3-K, Akt, and cancer cell growth.
You-Hong Hu, Li-Xin Qiao, Shaomeng Wang, Suo-Bao Rong +5 more
2000Journal of Medicinal Chemistry216 citations Open access
Semantic Scholar
Thioredoxin-1 binds to the C2 domain of PTEN inhibiting PTEN's lipid phosphatase activity and membrane binding: a mechanism for the functional loss of PTEN's tumor suppressor activity.
E. Meuillet, D. Mahadevan, M. Berggren, A. Coon +1 more
2004Archives of Biochemistry and Biophysics192 citations
Semantic Scholar
Interaction of the Extracellular Domain of the Epidermal Growth Factor Receptor with Gangliosides*
E. Miljan, E. Meuillet, B. Mania-Farnell, D. George +3 more
2002Journal of Biological Chemistry169 citations Open access
Semantic Scholar
Deoxycholic Acid Induces Intracellular Signaling through Membrane Perturbations*
Samira Jean-Louis, Sandeep Akare, M. A. Ali, Eugene A. Mash +2 more
2006Journal of Biological Chemistry134 citations Open access
Semantic Scholar
Identification and development of mPGES-1 inhibitors: where we are at?
Hui-Hua Chang, E. Meuillet
2011Future Medicinal Chemistry96 citations Open access
Semantic Scholar
While NM23-H2 may play an indirect role in transcriptional activation of c-myc gene expression, it does not cleave the NHE III1 element
T. Dexheimer, S. Carey, Zuo-He Song, V. Gokhale +8 more
2009Molecular Cancer Therapeutics95 citations Open access
Semantic Scholar
Chemoprevention of prostate cancer with selenium: An update on current clinical trials and preclinical findings
E. Meuillet, S. Stratton, Durga Prasad Cherukuri, Anne-Christine Goulet +3 more
2004Journal of Cellular Biochemistry95 citations
Semantic Scholar
mPGES-1 as a Target for Cancer Suppression
Masako Nakanishi, V. Gokhale, E. Meuillet, D. Rosenberg
2010Biochimie91 citations Open access
Semantic Scholar
The EP4 receptor antagonist, L-161,982, blocks prostaglandin E2-induced signal transduction and cell proliferation in HCA-7 colon cancer cells.
D. Cherukuri, Xiao B O Chen, Anne-Christine Goulet, R. Young +5 more
2007Experimental Cell Research88 citations Open access
Semantic Scholar
Time and dose-dependent radiosensitization of the glioblastoma multiforme U251 cells by the EGF receptor tyrosine kinase inhibitor ZD1839 ('Iressa').
B. Stea, R. Falsey, K. Kislin, J. Patel +5 more
2003Cancer Letters86 citations
Semantic Scholar
Specific inhibition of the Akt1 pleckstrin homology domain by D-3-deoxy-phosphatidyl-myo-inositol analogues.
E. Meuillet, D. Mahadevan, H. Vankayalapati, M. Berggren +4 more
2003Molecular Cancer Therapeutics81 citations
Semantic Scholar
Gene Transfection-mediated Overexpression of β1,4-N-Acetylglucosamine Bisecting Oligosaccharides in Glioma Cell Line U373 MG Inhibits Epidermal Growth Factor Receptor Function*
A. Rebbaa, H. Yamamoto, Tasuku Saito, E. Meuillet +5 more
1997Journal of Biological Chemistry81 citations Open access
Semantic Scholar
Discovery of a novel class of AKT pleckstrin homology (PH) domain inhibitors
D. Mahadevan, G. Powis, E. Mash, B. George +13 more
2008Molecular Cancer Therapeutics80 citations Open access
Semantic Scholar
Submolecular regulation of cell transformation by deuterium depleting water exchange reactions in the tricarboxylic acid substrate cycle
L. Boros, D. D'Agostino, H. Katz, J. Roth +2 more
2015Medical Hypotheses75 citations Open access
Semantic Scholar
Direct Inhibition of Hypoxia-Inducible Transcription Factor Complex with Designed Dimeric Epidithiodiketopiperazine
Katherine M. Block, Hui Wang, L. Szabó, Nathan W. Polaske +8 more
2009Journal of the American Chemical Society74 citations Open access
Semantic Scholar
Molecular pharmacology and antitumor activity of PHT-427 a novel AKT/PDPK1 pleckstrin homology domain inhibitor
E. Meuillet, Zuo-He Song, Robert Lemos, N. Ihle +12 more
2010Molecular Cancer Therapeutics71 citations Open access
Semantic Scholar
Modulation of EGF receptor activity by changes in the GM3 content in a human epidermoid carcinoma cell line, A431.
E. Meuillet, B. Mania-Farnell, D. George, J. Inokuchi +1 more
2000Experimental Cell Research68 citations
Semantic Scholar
Sialidase gene transfection enhances epidermal growth factor receptor activity in an epidermoid carcinoma cell line, A431.
E. Meuillet, R. Kroes, H. Yamamoto, T. G. Warner +6 more
1999Cancer Research67 citations
Semantic Scholar
Vascular endothelial growth factor receptor-1 and receptor-2 initiate a phosphatidylinositide 3-kinase-dependent clonogenic response in acute myeloid leukemia cells.
A. List, B. Glinsmann-Gibson, Chad Stadheim, E. Meuillet +2 more
2004Experimental Hematology61 citations Open access
Semantic Scholar
In vitro and In vivo Activity of Novel Small-Molecule Inhibitors Targeting the Pleckstrin Homology Domain of Protein Kinase B/AKT
Sylvestor A. Moses, M. A. Ali, Zuo-He Song, Lei Du-Cuny +8 more
2009Cancer Research59 citations Open access
Semantic Scholar
In vivo molecular pharmacology and antitumor activity of the targeted Akt inhibitor PX-316.
E. Meuillet, N. Ihle, A. Baker, Jaime M. C. Gard +7 more
2004Oncology Research57 citations Open access
Semantic Scholar
Molecular modeling studies of the Akt PH domain and its interaction with phosphoinositides.
Suo-Bao Rong, Youhong Hu, I. Enyedy, G. Powis +5 more
2001Journal of Medicinal Chemistry56 citations
Semantic Scholar
Novel Inhibitors of AKT: Assessment of a Different Approach Targeting the Pleckstrin Homology Domain
E. Meuillet
2011Current Medicinal Chemistry53 citations Open access
Semantic Scholar
Ganglioside modulates ligand binding to the epidermal growth factor receptor.
Xiao-Qi Wang, Zakia Rahman, P. Sun, E. Meuillet +4 more
2001Journal of Investigative Dermatology48 citations Open access
Semantic Scholar
Differential modulation of basic fibroblast and epidermal growth factor receptor activation by ganglioside GM3 in cultured retinal Müller glia
E. Meuillet, G. Cremel, H. Dreyfus, D. Hicks
1996Glia48 citations
Semantic Scholar
Synthesis and Biological Activity of 2-Aminothiazoles as Novel Inhibitors of PGE2 Production in Cells
Breland E. Smith, Hui-Hua Chang, F. Medda, V. Gokhale +4 more
2012Bioorganic & Medicinal Chemistry Letters46 citations Open access
Semantic Scholar
Pleckstrin Homology [PH] domain, structure, mechanism, and contribution to human disease.
G. Powis, E. Meuillet, M. Indarte, Garrett Booher +1 more
2023Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie44 citations Open access
Semantic Scholar
Targeting inflammation: multiple innovative ways to reduce prostaglandin E2
Jessica Norberg, E. Sells, Hui-Hua Chang, Srinivas R. Alla +2 more
2013Pharmaceutical Patent Analyst43 citations Open access
Semantic Scholar
Contextual inhibition of fatty acid synthesis by metformin involves glucose-derived acetyl-CoA and cholesterol in pancreatic tumor cells
Mary Jo Castro Cantoria, L. Boros, E. Meuillet
2013Metabolomics34 citations Open access
Semantic Scholar
Recent Development of Anticancer Therapeutics Targeting Akt
J. Morrow, Lei Du-Cuny, Lu Chen, E. Meuillet +3 more
2011Recent Patents on Anti-Cancer Drug Discovery34 citations Open access
Semantic Scholar
Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain
Lei Du-Cuny, Zuo-He Song, Sylvestor A. Moses, G. Powis +3 more
2009Bioorganic & Medicinal Chemistry32 citations Open access
Semantic Scholar
Nanoparticle delivery of an AKT/PDK1 inhibitor improves the therapeutic effect in pancreatic cancer
A. Lucero-Acuña, J. Jeffery, E. Abril, R. Nagle +3 more
2014International Journal of Nanomedicine28 citations Open access
Semantic Scholar
Development of sulfonamide AKT PH domain inhibitors
A. Ahad, Zuo-He Song, Lei Du-Cuny, Sylvestor A. Moses +5 more
2011Bioorganic & Medicinal Chemistry28 citations Open access
Semantic Scholar
Novel Inhibitors Induce Large Conformational Changes of GAB1 Pleckstrin Homology Domain and Kill Breast Cancer Cells
Lu Chen, Lei Du-Cuny, Sylvestor A. Moses, S. Dumas +5 more
2015PLoS Comput. Biol.27 citations Open access
Semantic Scholar
The matrix protein CCN1/CYR61 is required for αVβ5-mediated cancer cell migration
J. Jandova, Tracey E. Beyer, E. Meuillet, George S. Watts
2012Cell Biochemistry and Function26 citations Open access
Semantic Scholar
Sodium Selenite Increases the Activity of the Tumor Suppressor Protein, PTEN in DU-145 Prostate Cancer Cells
M. Berggren, S. Sittadjody, Zuo-He Song, J. Samira +2 more
2009Nutrition and Cancer26 citations Open access
Semantic Scholar
Incorporation of exogenous lipids modulates insulin signaling in the hepatoma cell line, HepG2.
E. Meuillet, Valérie Leray, Pierre Hubert, C. Leray +1 more
1999Biochimica et Biophysica Acta24 citations Open access
Semantic Scholar
Current status of targeted microbubbles in diagnostic molecular imaging of pancreatic cancer
Natacha Jugniot, Rakesh Bam, E. Meuillet, E. Unger +1 more
2020Bioengineering & Translational Medicine23 citations Open access
Semantic Scholar
Improved Treatment of Pancreatic Cancer With Drug Delivery Nanoparticles Loaded With a Novel AKT/PDK1 Inhibitor
Joseph E. Kobes, Iman Daryaei, C. Howison, J. Bontrager +3 more
2016Pancreas22 citations Open access
Semantic Scholar
Regulation of the activity of the tumor suppressor PTEN by thioredoxin in Drosophila melanogaster.
Zuo-He Song, N. Saghafi, V. Gokhale, Marc C. Brabant +1 more
2007Experimental Cell Research22 citations Open access
Semantic Scholar
An inhibitor of the pleckstrin homology domain of CNK1 selectively blocks the growth of mutant KRAS cells and tumors
M. Indarte, Roisin Puentes, Marco Maruggi, N. Ihle +13 more
2019Cancer Research19 citations Open access
Semantic Scholar
3-Deoxy-3-substituted-D-myo-inositol imidazolyl ether lipid phosphates and carbonate as inhibitors of the phosphatidylinositol 3-kinase pathway and cancer cell growth.
You-Hong Hu, E. Meuillet, M. Berggren, G. Powis +1 more
2001Bioorganic & Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
SUPEROXIDE DISMUTASE IS REGULATED BY LAMMER KINASE IN DROSOPHILA AND HUMAN CELLS
B. James, W. Staatz, S. Wilkinson, E. Meuillet +1 more
2008Free Radical Biology & Medicine17 citations Open access
Semantic Scholar
Gangliosides and Neurotrophic Growth Factors in the Retina: Molecular Interactions and Applications as Neuroprotective Agents a
H. Dreyfus, J. Sahel, V. Heidinger, S. Mohand-Said +4 more
1998Annals of the New York Academy of Sciences17 citations
Semantic Scholar
Metformin modulates insulin receptor signaling in normal and cholesterol-treated human hepatoma cells (HepG2).
E. Meuillet, N. Wiernsperger, B. Mania-Farnell, Pierre Hubert +1 more
1999European Journal of Pharmacology15 citations
Semantic Scholar
Lipid Modulation of Insulin Receptor Tyrosine Kinase Activity in Cultured Cells, Animals, and Reconstituted Systems a
Gérard Crémel, M. Ficková, I. Klimes̆, C. Leray +5 more
1993Annals of the New York Academy of Sciences14 citations
Semantic Scholar
Ganglioside effects on basic fibroblast and epidermal growth factor receptors in retinal glial cells.
E. Meuillet, Gérard Crémel, D. Hicks, H. Dreyfus
1996Journal of Lipid Mediators and Cell Signalling13 citations
Semantic Scholar
Towards the Clinical Development and Validation of a Thy1-Targeted Ultrasound Contrast Agent for the Early Detection of Pancreatic Ductal Adenocarcinoma
Rakesh Bam, Iman Daryaei, Lotfi Abou-Elkacem, J. Vilches-Moure +6 more
2020Investigative Radiology12 citations Open access
Semantic Scholar
Metformin and Pancreatic Cancer Metabolism
Mary Jo Castro Cantoria, Hitendra R. H. Patel, L. Boros, E. Meuillet
201412 citations Open access
Semantic Scholar

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