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L. Boros · SciRah

Researcher profile · Semantic Scholar

L. Boros

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L. Boros — researcher profile on SciRah

h-index: 47
Works: 129
Citations: 6,570

Most-cited papers

A roadmap for interpreting 13C metabolite labeling patterns from cells
J. Buescher, M. Antoniewicz, L. Boros, Shawn C. Burgess +33 more
2015Current Opinion in Biotechnology597 citations Open access
Semantic Scholar
Transcription factor NRF2 regulates miR-1 and miR-206 to drive tumorigenesis.
Anju Singh, Christine Happel, S. Manna, G. Acquaah-Mensah +12 more
2013Journal of Clinical Investigation312 citations Open access
Semantic Scholar
Metabolic control analysis in drug discovery and disease
M. Cascante, L. Boros, B. Comin-Anduix, P. De Atauri +2 more
2002Nature Biotechnology285 citations
Semantic Scholar
Abstract C151: Contribution of serine, folate, and glycine metabolism to the ATP, NADPH, and purine requirements of cancer cells.
Philip M. Tedeschi, E. Markert, M. Gounder, Hongxia Lin +8 more
2013243 citations
Semantic Scholar
PGC1α promotes tumor growth by inducing gene expression programs supporting lipogenesis
Kavita Bhalla, Bor-Jang Hwang, Ruby E. Dewi, Li-Wen Ou +7 more
2011Cancer Research185 citations Open access
Semantic Scholar
Fructose induces transketolase flux to promote pancreatic cancer growth.
Hai-Bo Liu, Dan-Shan Huang, David McArthur, L. Boros +2 more
2010Cancer Research184 citations Open access
Semantic Scholar
Metabolic strategy of boar spermatozoa revealed by a metabolomic characterization
Silvia Marín, Kelly Chiang, S. Bassilian, W. Lee +6 more
2003FEBS Letters155 citations Open access
Semantic Scholar
Metabolic profiling of cell growth and death in cancer: applications in drug discovery.
L. Boros, M. Cascante, W. Lee
2002Drug Discovery Today151 citations
Semantic Scholar
Abnormalities in Glucose Uptake and Metabolism in Imatinib-Resistant Human BCR-ABL–Positive Cells
Douglas J. Kominsky, Jelena Klawitter, Jaimi L. Brown, L. Boros +3 more
2009Clinical Cancer Research121 citations Open access
Semantic Scholar
Fermented Wheat Germ Extract Inhibits Glycolysis/Pentose Cycle Enzymes and Induces Apoptosis through Poly(ADP-ribose) Polymerase Activation in Jurkat T-cell Leukemia Tumor Cells*
B. Comin-Anduix, L. Boros, Silvia Marín, J. Boren +6 more
2002Journal of Biological Chemistry118 citations Open access
Semantic Scholar
K-ras Codon-Specific Mutations Produce Distinctive Metabolic Phenotypes in Human Fibroblasts
Pedro Vizán, L. Boros, A. Figueras, G. Capellá +5 more
2005104 citations
Semantic Scholar
Cancer-associated Isocitrate Dehydrogenase 1 (IDH1) R132H Mutation and d-2-Hydroxyglutarate Stimulate Glutamine Metabolism under Hypoxia*
Z. Reitman, Christopher G. Duncan, E. Poteet, Ali Winters +6 more
2014Journal of Biological Chemistry85 citations Open access
Semantic Scholar
An Inhibitor of GSK3B and HDACs Kills Pancreatic Cancer Cells and Slows Pancreatic Tumor Growth and Metastasis in Mice
M. Edderkaoui, C. Chheda, Badr Soufi, Fouzia Zayou +13 more
2018Gastroenterology82 citations Open access
Semantic Scholar
The Stable Isotope-based Dynamic Metabolic Profile of Butyrate-induced HT29 Cell Differentiation*
J. Boren, W. Lee, S. Bassilian, J. Centelles +4 more
2003Journal of Biological Chemistry77 citations Open access
Semantic Scholar
Submolecular regulation of cell transformation by deuterium depleting water exchange reactions in the tricarboxylic acid substrate cycle
L. Boros, D. D'Agostino, H. Katz, J. Roth +2 more
2015Medical Hypotheses75 citations Open access
Semantic Scholar
Anaplerotic Metabolism of Alloreactive T Cells Provides a Metabolic Approach To Treat Graft-Versus-Host Disease
G. Glick, R. Rossignol, C. Lyssiotis, D. Wahl +11 more
2014Journal of Pharmacology and Experimental Therapeutics73 citations Open access
Semantic Scholar
In utero nicotine exposure alters fetal rat lung alveolar type II cell proliferation, differentiation, and metabolism.
V. Rehan, Ying Wang, S. Sugano, Jamie Santos +5 more
2007American Journal of Physiology - Lung cellular and Molecular Physiology72 citations
Semantic Scholar
Diverse mechanisms of growth inhibition by luteolin, resveratrol, and quercetin in MIA PaCa-2 cells: a comparative glucose tracer study with the fatty acid synthase inhibitor C75
D. M. Harris, Lu-Yi Li, M. Chen, F. T. Lagunero +2 more
2011Metabolomics70 citations Open access
Semantic Scholar
Fermented Wheat Germ Extract (Avemar) in the Treatment of Cancer and Autoimmune Diseases
L. Boros, M. Nichelatti, Y. Shoenfeld
2005Annals of the New York Academy of Sciences68 citations
Semantic Scholar
Defective RNA ribose synthesis in fibroblasts from patients with thiamine-responsive megaloblastic anemia (TRMA).
L. Boros, Mara P. Steinkamp, J. Fleming, W. Lee +2 more
2003Blood68 citations Open access
Semantic Scholar
Iron regulates glucose homeostasis in liver and muscle via AMP‐activated protein kinase in mice
Jingyu Huang, J. Simcox, T. Mitchell, Deborah L. Jones +5 more
2013The FASEB Journal65 citations Open access
Semantic Scholar
Acidosis induces reprogramming of cellular metabolism to mitigate oxidative stress
Gregory M. LaMonte, Xiao-Hu Tang, J. L. Chen, Jian-Li Wu +8 more
2013Cancer & Metabolism65 citations Open access
Semantic Scholar
Growth stimulation of COX-2-negative pancreatic cancer by a selective COX-2 inhibitor.
G. Eibl, Y. Takata, L. Boros, Joey Liu +3 more
2005Cancer Research65 citations Open access
Semantic Scholar
K-ras codon-specific mutations produce distinctive metabolic phenotypes in NIH3T3 mice [corrected] fibroblasts.
Pedro Vizán, L. Boros, A. Figueras, G. Capellá +5 more
2005Cancer Research65 citations
Semantic Scholar
Direct Spectrophotometric Determination of Serum Fructose in Pancreatic Cancer Patients
H. Hui, Dan-Shan Huang, David McArthur, Nicholas N. Nissen +2 more
2009Pancreas64 citations
Semantic Scholar
Detection of Resistance to Imatinib by Metabolic Profiling
N. Serkova, L. Boros
2005American Journal of Pharmacogenomics64 citations
Semantic Scholar
5′-AMP-activated Protein Kinase (AMPK) Supports the Growth of Aggressive Experimental Human Breast Cancer Tumors*
K. Laderoute, J. Calaoagan, W. Chao, Đ. Đình +7 more
2014Journal of Biological Chemistry60 citations Open access
Semantic Scholar
Dual modulation of both lipid oxidation and synthesis by peroxisome proliferator‐activated receptor‐γ coactivator‐1α and ‐1β in cultured myotubes
D. Espinoza, L. Boros, Sarah Crunkhorn, H. Gami +1 more
2010The FASEB Journal60 citations Open access
Semantic Scholar
AMPK Activation through Mitochondrial Regulation Results in Increased Substrate Oxidation and Improved Metabolic Parameters in Models of Diabetes
Y. Jenkins, Tianduo Sun, V. Markovtsov, M. Foretz +35 more
2013PLoS ONE58 citations Open access
Semantic Scholar
Dynamic profiling of the glucose metabolic network in fasted rat hepatocytes using [1,2-13C2]glucose.
Silvia Marín, W. Lee, S. Bassilian, Shu K. Lim +5 more
2004Biochemical Journal58 citations Open access
Semantic Scholar
A Metabolic Hypothesis of Cell Growth and Death in Pancreatic Cancer
L. Boros, W. Lee, V. L. Go
2002Pancreas58 citations
Semantic Scholar
Metabolic biomarker and kinase drug target discovery in cancer using stable isotope-based dynamic metabolic profiling (SIDMAP).
L. Boros, D. Brackett, G. Harrigan
2003Current Cancer Drug Targets57 citations
Semantic Scholar
Polymorphism of the TNF-α, HSP70-2, and CD14 Genes Increases Susceptibility to Severe Acute Pancreatitis
A. Balog, Z. Gyulai, L. Boros, G. Farkas +3 more
2005Pancreas54 citations
Semantic Scholar
[1,2-13C2]-D-Glucose Profiles of the Serum, Liver, Pancreas, and DMBA-Induced Pancreatic Tumors of Rats
L. Boros, M. Lerner, D. Morgan, Stephanie L Taylor +3 more
2005Pancreas54 citations
Semantic Scholar
Fructose impairs glucose-induced hepatic triglyceride synthesis
Dan-Shan Huang, Tania Dhawan, Stepheng Young, W. Yong +2 more
2011Lipids in Health and Disease53 citations Open access
Semantic Scholar
De novo lipogenesis represents a therapeutic target in mutant Kras non‐small cell lung cancer
Anju Singh, Christian F Ruiz, Kavita Bhalla, John A. Haley +15 more
2018The FASEB Journal44 citations Open access
Semantic Scholar
Increased Glucose Disposal and AMP-dependent Kinase Signaling in a Mouse Model of Hemochromatosis*
Jingyu Huang, J. Gabrielsen, Robert C. Cooksey, Bai Luo +8 more
2007Journal of Biological Chemistry44 citations Open access
Semantic Scholar
Assessment of usnic acid toxicity in rat primary hepatocytes using ¹³C isotopomer distribution analysis of lactate, glutamate and glucose.
B. Sonko, T. Schmitt, Lei Guo, Q. Shi +3 more
2011Food and Chemical Toxicology39 citations Open access
Semantic Scholar
PNU-91325 increases fatty acid synthesis from glucose and mitochondrial long chain fatty acid degradation: a comparative tracer-based metabolomics study with rosiglitazone and pioglitazone in HepG2 cells
G. Harrigan, J. Colca, S. Szalma, L. Boros
2006Metabolomics38 citations Open access
Semantic Scholar
Oxygen-induced metabolic changes and transdifferentiation in immature fetal rat lung lipofibroblasts.
L. Boros, J. Torday, W. Paul Lee, V. Rehan
2002Molecular Genetics and Metabolism38 citations
Semantic Scholar
Single valproic acid treatment inhibits glycogen and RNA ribose turnover while disrupting glucose-derived cholesterol synthesis in liver as revealed by the [U-13C6]-d-glucose tracer in mice
R. Beger, D. K. Hansen, L. Schnackenberg, B. M. Cross +4 more
2009Metabolomics37 citations Open access
Semantic Scholar
Medicinal chemistry, metabolic profiling and drug target discovery: a role for metabolic profiling in reverse pharmacology and chemical genetics.
G. Harrigan, D. Brackett, L. Boros
2005Mini-Reviews in Medical Chemistry37 citations
Semantic Scholar
Use of metabolic pathway flux information in targeted cancer drug design
L. Boros, N. Serkova, M. Cascante, W. Lee
200437 citations
Semantic Scholar
Contextual inhibition of fatty acid synthesis by metformin involves glucose-derived acetyl-CoA and cholesterol in pancreatic tumor cells
Mary Jo Castro Cantoria, L. Boros, E. Meuillet
2013Metabolomics34 citations Open access
Semantic Scholar
Pharmacological Targeting of Glucagon and Glucagon-Like Peptide 1 Receptors Has Different Effects on Energy State and Glucose Homeostasis in Diet-Induced Obese Mice
W. Gu, D. Lloyd, Narumol Chinookswong, R. Komorowski +7 more
2011Journal of Pharmacology and Experimental Therapeutics33 citations
Semantic Scholar
Metabolic fate of fructose in human adipocytes: a targeted 13C tracer fate association study
Vijayalakshmi Varma, L. Boros, G. Nolen, Ching-Wei Chang +3 more
2014Metabolomics32 citations Open access
Semantic Scholar
Deuterium Depletion Inhibits Cell Proliferation, RNA and Nuclear Membrane Turnover to Enhance Survival in Pancreatic Cancer
L. Boros, I. Somlyai, B. Z. Kovács, L. Puskás +4 more
2021Cancer Control: Journal of the Moffitt Cancer Cente31 citations Open access
Semantic Scholar
Metabolomics in Alcohol Research and Drug Development
G. Harrigan, Greg Maguire, L. Boros
2008Alcohol Research and Health27 citations
Semantic Scholar
Spermatogenetic expression of RNA-binding motif protein 7, a protein that interacts with splicing factors.
Taylor B. Guo, L. Boros, Kam C Chan, A. S. Sinha Hikim +4 more
2003Journal of Andrology27 citations
Semantic Scholar
Metabolic targeted therapy of cancer: current tracer technologies and future drug design strategies in the old metabolic network
L. Boros
2005Metabolomics26 citations Open access
Semantic Scholar

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M. Cascante×10
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M. Cascante — researcher profile on SciRah
W. Lee×8
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W. Lee — researcher profile on SciRah
S. Bassilian×6
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S. Bassilian — researcher profile on SciRah
J. Centelles×5
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Shu K. Lim — researcher profile on SciRah

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G. Harrigan — researcher profile on SciRah

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E. Meuillet — researcher profile on SciRah

Geoffrey D. Girnun×3

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Geoffrey D. Girnun — researcher profile on SciRah

Dan-Shan Huang×3

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Dan-Shan Huang — researcher profile on SciRah

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Silvia Marín×3

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Silvia Marín — researcher profile on SciRah

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N. Serkova — researcher profile on SciRah