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D. Lorimer · SciRah

Researcher profile · Semantic Scholar

D. Lorimer

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D. Lorimer — researcher profile on SciRah

h-index: 23
Works: 105
Citations: 2,783

Most-cited papers

Structure of nucleotide‐binding domain 1 of the cystic fibrosis transmembrane conductance regulator
H. Lewis, S. Buchanan, S. Burley, K. Conners +20 more
2004EMBO Journal426 citations Open access
Semantic Scholar
Impact of the ΔF508 Mutation in First Nucleotide-binding Domain of Human Cystic Fibrosis Transmembrane Conductance Regulator on Domain Folding and Structure*
H. Lewis, Xun Zhao, Chi Wang, J. Sauder +10 more
2005Journal of Biological Chemistry292 citations Open access
Semantic Scholar
In vivo progression of LAPC-9 and LNCaP prostate cancer models to androgen independence is associated with increased expression of insulin-like growth factor I (IGF-I) and IGF-I receptor (IGF-IR).
T. Nickerson, F. Chang, D. Lorimer, S. Smeekens +2 more
2001Cancer Research259 citations
Semantic Scholar
Cloning and characterization of a novel human histone deacetylase, HDAC8.
J. Buggy, Mindy L Compton Sideris, Polly Mak, D. Lorimer +2 more
2000Biochemical Journal201 citations Open access
Semantic Scholar
Structural model of the dimeric Parkinson’s protein LRRK2 reveals a compact architecture involving distant interdomain contacts
Giambattista Guaitoli, Francesco Raimondi, Bernd K. Gilsbach, Y. Gómez-Llorente +18 more
2016Proceedings of the National Academy of Sciences of the United States of America144 citations Open access
Semantic Scholar
Expression of the catalytic domain of myosin light chain kinase increases paracellular permeability.
G. Hecht, L. Pestic, G. Nikcevic, A. Koutsouris +6 more
1996American Journal of Physiology143 citations
Semantic Scholar
Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis
B. Baragaña, B. Forte, Ryan Choi, Stephen Nakazawa-Hewitt +73 more
2019Proceedings of the National Academy of Sciences of the United States of America126 citations Open access
Semantic Scholar
Increasing the Structural Coverage of Tuberculosis Drug Targets
L. Baugh, Isabelle Q. Phan, D. Begley, M. Clifton +31 more
2014Tuberculosis123 citations Open access
Semantic Scholar
Artificial Neural Networks Trained to Detect Viral and Phage Structural Proteins
V. Seguritan, Nélson Alves, Michael Arnoult, Amy C. Raymond +4 more
2012PLoS Comput. Biol.100 citations Open access
Semantic Scholar
Overcoming adaptive therapy resistance in AML by targeting immune response pathways
Katelyn Melgar, Morgan M. Walker, LaQuita M. Jones, L. Bolanos +21 more
2019Science Translational Medicine88 citations Open access
Semantic Scholar
Cloning and quantification of galanin-1 receptor expression by mucosal cells lining the human gastrointestinal tract.
D. Lorimer, R. Benya
1996Biochemical and Biophysical Research Communications - BBRC66 citations
Semantic Scholar
Combined protein construct and synthetic gene engineering for heterologous protein expression and crystallization using Gene Composer
Amy C. Raymond, S. Lovell, D. Lorimer, John Walchli +6 more
2009BMC Biotechnology59 citations Open access
Semantic Scholar
Gene Composer: database software for protein construct design, codon engineering, and gene synthesis
D. Lorimer, Amy C. Raymond, John Walchli, M. Mixon +5 more
2009BMC Biotechnology56 citations Open access
Semantic Scholar
Challenging the state-of-the-art in protein structure prediction: Highlights of experimental target structures for the 10th Critical Assessment of Techniques for Protein Structure Prediction Experiment CASP10
A. Kryshtafovych, J. Moult, Patrick M. Bales, J. Bazan +19 more
2014Proteins: Structure, Function, and Bioinformatics55 citations Open access
Semantic Scholar
New York-Structural GenomiX Research Consortium (NYSGXRC): A Large Scale Center for the Protein Structure Initiative
J. Bonanno, S. Almo, A. Bresnick, Mark R. Chance +18 more
2005Journal of Structural and Functional Genomics53 citations
Semantic Scholar
High-throughput Limited Proteolysis/Mass Spectrometry for Protein Domain Elucidation
Xia Gao, K. Bain, J. Bonanno, M. Buchanan +8 more
2005Journal of Structural and Functional Genomics52 citations
Semantic Scholar
Cloning, chromosomal location, and transcriptional regulation of the human galanin-1 receptor gene (GALN1R).
D. Lorimer, Kristina Matkowskj, R. Benya
1997Biochemical and Biophysical Research Communications - BBRC38 citations
Semantic Scholar
Structure and function of a cyanophage-encoded peptide deformylase
Jeremy A. Frank, D. Lorimer, M. Youle, P. Witte +6 more
2013The ISME Journal36 citations Open access
Semantic Scholar
Structure of acid deoxyribonuclease
A. Varela-Ramírez, J. Abendroth, Adrian A. Mejia, Isabelle Q. Phan +3 more
2017Nucleic Acids Research32 citations Open access
Semantic Scholar
Mycofactocin-associated mycobacterial dehydrogenases with non-exchangeable NAD cofactors
D. Haft, P. G. Pierce, S. Mayclin, A. Sullivan +9 more
2017Scientific Reports29 citations Open access
Semantic Scholar
Tyrosine aminotransferase from Leishmania infantum: A new drug target candidate
M. Moreno, A. Alonso, P. J. Alcolea, Ariel B. Abramov +7 more
2014International Journal for Parasitology: Drugs and Drug Resistance28 citations Open access
Semantic Scholar
Structural characterisation of hemagglutinin from seven Influenza A H1N1 strains reveal diversity in the C05 antibody recognition site
S. Ghafoori, Gayle F. Petersen, D. G. Conrady, B. Calhoun +7 more
2023Scientific Reports23 citations Open access
Semantic Scholar
Naegleria fowleri: Protein structures to facilitate drug discovery for the deadly, pathogenic free-living amoeba
Kayleigh Barrett, Logan M Tillery, J. Goldstein, Jared W. Lassner +27 more
2020bioRxiv23 citations Open access
Semantic Scholar
Structure of tyrosine aminotransferase from Leishmania infantum
M. Moreno, Ariel B. Abramov, Jan Abendroth, A. Alonso +6 more
2014Acta Crystallographica Section F Structural Biology Communications22 citations Open access
Semantic Scholar
Company Says It Mapped Part of SARS Virus
J. Bonanno, R. Fowler, S. Gupta, J. Hendle +7 more
200319 citations
Semantic Scholar
Structures of plasmepsin X from P. falciparum reveal a novel inactivation mechanism of the zymogen and molecular basis for binding of inhibitors in mature enzyme
P. Kesari, Anuradha Deshmukh, N. Pahelkar, A. Suryawanshi +12 more
2021bioRxiv18 citations Open access
Semantic Scholar
Structural characterization of a GNAT family acetyltransferase from Elizabethkingia anophelis bound to acetyl-CoA reveals a new dimeric interface
P. Shirmast, S. Ghafoori, R. Irwin, J. Abendroth +4 more
2021Scientific Reports17 citations Open access
Semantic Scholar
Some of the most interesting CASP11 targets through the eyes of their authors
A. Kryshtafovych, J. Moult, A. Baslé, A. Burgin +20 more
2015Proteins: Structure, Function, and Bioinformatics17 citations Open access
Semantic Scholar
A Structural Biology Approach Enables the Development of Antimicrobials Targeting Bacterial Immunophilins
D. Begley, D. Fox, D. Jenner, C. Juli +18 more
2013Antimicrobial Agents and Chemotherapy17 citations Open access
Semantic Scholar
Ligand co-crystallization of aminoacyl-tRNA synthetases from infectious disease organisms
Spencer O. Moen, T. Edwards, D. Dranow, M. Clifton +7 more
2017Scientific Reports16 citations Open access
Semantic Scholar
Expression of a mutant myosin light chain that cannot be phosphorylated increases paracellular permeability.
S. Gandhi, D. Lorimer, P. de Lanerolle
1997American Journal of Physiology16 citations
Semantic Scholar
Structural characterization of a Type B chloramphenicol acetyltransferase from the emerging pathogen Elizabethkingia anophelis NUHP1
S. Ghafoori, A. Robles, Angelika Arada, P. Shirmast +7 more
2021Scientific Reports13 citations Open access
Semantic Scholar
Toward a structome of Acinetobacter baumannii drug targets
Logan M Tillery, Kayleigh Barrett, D. Dranow, Justin Craig +9 more
2020Protein Science12 citations Open access
Semantic Scholar
Challenging the state of the art in protein structure prediction: Highlights of experimental target structures for the 10th critical assessment of techniques for protein structure prediction experiment CASP10
D. Lorimer, Hartmut, Luecke, D. Nelson
201512 citations Open access
Semantic Scholar
Structural characterization of aspartate-semialdehyde dehydrogenase from Pseudomonas aeruginosa and Neisseria gonorrhoeae
S. Teakel, J. Fairman, M. Muruthi, J. Abendroth +5 more
2022Scientific Reports11 citations Open access
Semantic Scholar
High-resolution Crystal Structure of Dimeric VP40 From Sudan ebolavirus.
M. Clifton, J. Bruhn, Kateri A. Atkins, T. Webb +6 more
2015Journal of Infectious Diseases11 citations Open access
Semantic Scholar
Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1
Spencer O. Moen, J. Abendroth, J. Fairman, Ruth O. Baydo +14 more
2014Scientific Reports11 citations Open access
Semantic Scholar
Structure of the Reston ebolavirus VP30 C-terminal domain
M. Clifton, R. Kirchdoerfer, Kateri A. Atkins, J. Abendroth +8 more
2014Acta Crystallographica Section F Structural Biology Communications11 citations Open access
Semantic Scholar
Structures of glyceraldehyde 3‐phosphate dehydrogenase in Neisseria gonorrhoeae and Chlamydia trachomatis
Kayleigh Barrett, D. Dranow, Isabelle Q. Phan, Samantha A. Michaels +20 more
2020Protein Science10 citations Open access
Semantic Scholar
Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP.
Spencer O. Moen, J. Fairman, Steve R. Barnes, A. Sullivan +6 more
2015Acta Crystallographica Section F Structural Biology Communications8 citations Open access
Semantic Scholar
Crystal structures of thiamine monophosphate kinase from Acinetobacter baumannii in complex with substrates and products
A. Sullivan, D. Dranow, P. Horanyi, D. Lorimer +2 more
2017Scientific Reports7 citations Open access
Semantic Scholar
Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia.
J. Abendroth, Ryan Choi, A. Wall, M. Clifton +6 more
2015Acta Crystallographica Section F Structural Biology Communications7 citations Open access
Semantic Scholar
Crystal structures of Mycobacterial MeaB and MMAA-like GTPases
T. Edwards, L. Baugh, Jameson Bullen, Ruth O. Baydo +11 more
2015Journal of Structural and Functional Genomics6 citations Open access
Semantic Scholar
Structures of a histidine triad family protein from Entamoeba histolytica bound to sulfate, AMP and GMP.
D. Lorimer, Ryan Choi, Ariel B. Abramov, Stephen Nakazawa-Hewitt +5 more
2015Acta Crystallographica Section F Structural Biology Communications4 citations Open access
Semantic Scholar
Broad-spectrum in vitro activity of macrophage infectivity potentiator inhibitors against Gram-negative bacteria and Leishmania major
J. Iwasaki, D. Lorimer, Mirella Vivoli-Vega, Emily A Kibble +22 more
2022Journal of Antimicrobial Chemotherapy3 citations Open access
Semantic Scholar
Crystal structure of chorismate mutase from Burkholderia phymatum.
O. Asojo, S. Subramanian, J. Abendroth, Ilyssa Exley +3 more
2018Acta Crystallographica Section F Structural Biology Communications2 citations Open access
Semantic Scholar
Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit
Brianna Armour, Steve R. Barnes, Spencer O. Moen, Eric R. Smith +7 more
2013Journal of Visualized Experiments2 citations Open access
Semantic Scholar
Characterization of a family I inorganic pyrophosphatase from Legionella pneumophila Philadelphia 1.
Julia Moorefield, Yagmur Konuk, Jordan O Norman, J. Abendroth +10 more
2023Acta Crystallographica Section F Structural Biology Communications1 citations Open access
Semantic Scholar
Structure of RND efflux system, outer membrane lipoprotein, NodT family from Burkholderia mallei ATCC 23344
P. Horanyi, D. Fox, J. Abendroth, D. Lorimer +1 more
20191 citations
Semantic Scholar
Crystal Structure of Human DHFR complexed with NADP and N10formyltetrahydrofolate
S. Mayclin, D. Dranow, D. Lorimer
20181 citations
Semantic Scholar

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P. Myler×21
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B. Staker×13
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W. Van Voorhis×11

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Isabelle Q. Phan×8

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Amy C. Raymond×8

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A. Burgin — researcher profile on SciRah

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