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J. Fairman · SciRah

Researcher profile · Semantic Scholar

J. Fairman

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J. Fairman — researcher profile on SciRah

h-index: 15
Works: 50
Citations: 1,384

Most-cited papers

The structural biology of β-barrel membrane proteins: a summary of recent reports
J. Fairman, N. Noinaj, S. Buchanan
2011Current Opinion in Structural Biology266 citations Open access
Semantic Scholar
STRUCTURAL BASIS FOR ALLOSTERIC REGULATION OF HUMAN RIBONUCLEOTIDE REDUCTASE BY NUCLEOTIDE-INDUCED OLIGOMERIZATION
J. Fairman, S. R. Wijerathna, Md. Faiz Ahmad, Hai Xu +10 more
2011Nature Structural &Molecular Biology175 citations Open access
Semantic Scholar
Structural engineering of a phage lysin that targets Gram-negative pathogens
P. Lukacik, T. J. Barnard, P. Keller, K. S. Chaturvedi +8 more
2012Proceedings of the National Academy of Sciences of the United States of America159 citations Open access
Semantic Scholar
Combining Functional and Structural Genomics to Sample the Essential Burkholderia Structome
L. Baugh, L. Gallagher, Rapatbhorn Patrapuvich, M. Clifton +23 more
2013PLoS ONE128 citations Open access
Semantic Scholar
Increasing the Structural Coverage of Tuberculosis Drug Targets
L. Baugh, Isabelle Q. Phan, D. Begley, M. Clifton +31 more
2014Tuberculosis123 citations Open access
Semantic Scholar
The crystal structure of BamB suggests interactions with BamA and its role within the BAM complex
N. Noinaj, J. Fairman, S. Buchanan
2011Journal of Molecular Biology98 citations Open access
Semantic Scholar
Crystal Structures of the Outer Membrane Domain of Intimin and Invasin from Enterohemorrhagic Escherichia coli and Enteropathogenic Yersinia pseudotuberculosis
J. Fairman, N. Dautin, Damian Wójtowicz, Wei Liu +6 more
2012Structure96 citations Open access
Semantic Scholar
Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation.
Hai Xu, C. Faber, T. Uchiki, J. Fairman +2 more
2006Proceedings of the National Academy of Sciences of the United States of America82 citations Open access
Semantic Scholar
Lab-in-the-loop therapeutic antibody design with deep learning
Nathan C. Frey, I. Hötzel, S. Stanton, Ryan L Kelly +60 more
2025bioRxiv46 citations Open access
Semantic Scholar
An O-Methyltransferase Is Required for Infection of Tick Cells by Anaplasma phagocytophilum
Adela S. Oliva Chávez, J. Fairman, R. Felsheim, C. M. Nelson +8 more
2015PLoS Pathogens38 citations Open access
Semantic Scholar
A Maltose-Binding Protein Fusion Construct Yields a Robust Crystallography Platform for MCL1
M. Clifton, D. Dranow, Alison J. Leed, B. Fulroth +14 more
2015PLoS ONE30 citations Open access
Semantic Scholar
The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: a Conformationally Flexible Pharmacophore
Hai Xu, J. Fairman, S. R. Wijerathna, N. Kreischer +4 more
2008Journal of Medicinal Chemistry27 citations Open access
Semantic Scholar
X-ray Crystallography and Isothermal Titration Calorimetry Studies of the Salmonella Zinc Transporter ZntB
Q. Wan, Md. Faiz Ahmad, J. Fairman, Bonnie M. Gorzelle +3 more
2011Structure25 citations Open access
Semantic Scholar
Single Diastereomer of a Macrolactam Core Binds Specifically to Myeloid Cell Leukemia 1 (MCL1).
Chao Fang, B. D'Souza, C. Thompson, M. Clifton +13 more
2014ACS Medicinal Chemistry Letters24 citations Open access
Semantic Scholar
Iron superoxide dismutases in eukaryotic pathogens: new insights from Apicomplexa and Trypanosoma structures.
Isabelle Q. Phan, D. Davies, N. Moretti, D. Shanmugam +7 more
2015Acta Crystallographica Section F Structural Biology Communications19 citations Open access
Semantic Scholar
Targeting the Large Subunit of Human Ribonucleotide Reductase for Cancer Chemotherapy
S. R. Wijerathna, Md. Faiz Ahmad, Hai Xu, J. Fairman +5 more
2011Pharmaceuticals14 citations Open access
Semantic Scholar
Structural characterization of aspartate-semialdehyde dehydrogenase from Pseudomonas aeruginosa and Neisseria gonorrhoeae
S. Teakel, J. Fairman, M. Muruthi, J. Abendroth +5 more
2022Scientific Reports11 citations Open access
Semantic Scholar
Structural analysis of H1N1 and H7N9 influenza A virus PA in the absence of PB1
Spencer O. Moen, J. Abendroth, J. Fairman, Ruth O. Baydo +14 more
2014Scientific Reports11 citations Open access
Semantic Scholar
Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP.
Spencer O. Moen, J. Fairman, Steve R. Barnes, A. Sullivan +6 more
2015Acta Crystallographica Section F Structural Biology Communications8 citations Open access
Semantic Scholar
Site-Specific Incorporation of Clickable d-Mannose Derivatives in the Lipopolysaccharide Core of the Pathogen Brucella abortus.
Marine Lacritick, A. Reboul, Rym Yahia Boudhar, E. Carlier +7 more
2025ACS Chemical Biology2 citations
Semantic Scholar
Multi-target Parallel Processing Approach for Gene-to-structure Determination of the Influenza Polymerase PB2 Subunit
Brianna Armour, Steve R. Barnes, Spencer O. Moen, Eric R. Smith +7 more
2013Journal of Visualized Experiments2 citations Open access
Semantic Scholar
The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase
Hai-Ying Xu, J. Fairman, S. R. Wijerathna, J. Lamacchia +4 more
20081 citations
Semantic Scholar
Crystal Structure of the PDE4D Catalytic Domain and UCR2 Regulatory Helix with T-48
D. Fox, J. Fairman, M. Gurney
20190 citations
Semantic Scholar
asymmetric hTNF-alpha
T. Arakaki, T. E. Edwards, J. Fairman, D. R. Davies +2 more
20190 citations
Semantic Scholar
Crystal Structure of the PDE4D Catalytic Domain and UCR2 Regulatory Helix with T-49
D. Fox, J. Fairman, M. Gurney
20190 citations
Semantic Scholar
Crystal Structure of the PDE4D Catalytic Domain and UCR2 Regulatory Helix with BPN14770
D. Fox, J. Fairman, M. Gurney
20190 citations
Semantic Scholar
Crystal Structure of the PDE4D Catalytic Domain and UCR2 Regulatory Helix with BPN5004
D. Fox, J. Fairman, M. Gurney
20180 citations
Semantic Scholar
Crystal structure of FcRn at pH3
D. Fox, J. Fairman
20180 citations
Semantic Scholar
Crystal structure of Fab fragment of anti-FcRn antibody DX-2507
T. Edwards, J. Fairman, A. Nixon, J. Kenniston
20170 citations
Semantic Scholar
X-ray Crystal Structure of an LpqH orthologue from Mycobacterium avium
J. Fairman, J. Abendroth, D. Lorimer, T. Edwards
20150 citations
Semantic Scholar
X-ray crystal structure of superoxide dismutase from Babesia bovis solved by Sulfur SAD
J. Fairman, M. Clifton, J. Abendroth, T. Edwards +1 more
20150 citations
Semantic Scholar
X-ray Crystal Structure of a Pyridoxine 5-prime-phosphate synthase from Pseudomonas aeruginosa
J. Fairman, J. Abendroth, D. Lorimer, T. Edwards
20150 citations
Semantic Scholar
Binding affinity (K D ) of ligands to MCL1 and MBP-MCL1.
M. Clifton, D. Dranow, Alison J. Leed, B. Fulroth +14 more
20150 citations Open access
Semantic Scholar
X-ray Crystal Structure of an Amino Acid Aminotransferase from Burkholderia pseudomallei Bound to the Co-factor Pyridoxal Phosphate
J. Fairman, D. M. Dranow, B. M. Taylor, D. Lorimer +1 more
20140 citations
Semantic Scholar
X-ray crystal structure of a putative D-amino acid aminotransferase from Burkholderia cenocepacia
J. Fairman, J. Abendroth, T. Edwards, D. Lorimer
20140 citations
Semantic Scholar
X-ray Crystal Structure of PA protein from Influenza strain H7N9
J. Fairman, Spencer O. Moen, M. Clifton, T. Edwards +1 more
20140 citations
Semantic Scholar
X-ray crystal structure of a D-amino acid aminotransferase from Burkholderia thailandensis E264 bound to the co-factor pyridoxal phosphate
J. Fairman, B. M. Taylor, T. Edwards, D. Lorimer
20140 citations
Semantic Scholar
X-ray crystal structure of an O-methyltransferase from Anaplasma phagocytophilum bound to SAM and a Manganese ion.
J. Fairman, J. Abendroth, D. Lorimer, T. Edwards
20140 citations
Semantic Scholar
X-ray crystal structure of the transmembrane beta-domain from invasin from Yersinia pseudotuberculosis
J. Fairman, N. Dautin, Damian Wójtowicz, L. Wei +7 more
20120 citations
Semantic Scholar
The crystal structure of an engineered phage lysin containing the binding domain of pesticin and the killing domain of T4-lysozyme
N. Seddiki, N. Noinaj, J. Fairman, P. Lukacik +2 more
20120 citations
Semantic Scholar
The crystal structure of pesticin-T4 lysozyme hybrid stabilized by engineered disulfide bonds
N. Seddiki, J. Fairman, N. Noinaj, P. Lukacik +2 more
20120 citations
Semantic Scholar
X-ray crystal structure of the transmembrane beta-domain from intimin from EHEC strain O157:H7
J. Fairman, N. Dautin, Damian Wójtowicz, L. Wei +7 more
20120 citations
Semantic Scholar
Crystal structure of human ribonucleotide reductase 1 bound to the effectors TTP and dATP
J. Fairman, S. R. Wijerathna, Hai Xu, C. Dealwis
20110 citations
Semantic Scholar
The crystal structure of BamB from the BAM complex in spacegroup P212121
N. Noinaj, J. Fairman, S. Buchanan
20110 citations
Semantic Scholar
Crystal structure of human ribonucleotide reductase 1 bound to the effector TTP and substrate GDP
J. Fairman, S. R. Wijerathna, Hai Xu, C. Dealwis
20110 citations
Semantic Scholar
Low resolution X-ray crystal structure of Yeast Rnr1p with dATP bound in the A-site
J. Fairman, S. R. Wijerathna, C. Dealwis
20110 citations
Semantic Scholar
Crystal structure of human ribonucleotide reductase 1 bound to the effector TTP
J. Fairman, S. R. Wijerathna, Hai Xu, C. Dealwis
20110 citations
Semantic Scholar
Structure-Function Studies of the Large Subunit of Ribonucleotide Reductase from Homo sapiens and Saccharomyces cerevisiae
J. Fairman
20090 citations
Semantic Scholar
Structures of Yeast Ribonucleotide Reductase I
Hai Xu, C. Faber, T. Uchiki, J. Fairman +2 more
20060 citations
Semantic Scholar
Structures of Yeast Ribonucleotide Reductase I complexed with Ligands and Subunit Peptides
C. Dealwis, Hai Xu, C. Faber, T. Uchiki +2 more
20060 citations
Semantic Scholar

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J. Abendroth×11
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