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H. Schut · SciRah

Researcher profile · Semantic Scholar

H. Schut

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H. Schut — researcher profile on SciRah

h-index: 33
Works: 97
Citations: 3,435

Most-cited papers

DNA adducts of heterocyclic amine food mutagens: implications for mutagenesis and carcinogenesis.
H. Schut, E. Snyderwine
1999Carcinogenesis346 citations
Semantic Scholar
Protection of conjugated linoleic acids against 2-amino-3- methylimidazo[4,5-f]quinoline-induced colon carcinogenesis in the F344 rat: a study of inhibitory mechanisms.
C. Liew, H. Schut, Sou F. Chin, M. Pariza +1 more
1995Carcinogenesis297 citations
Semantic Scholar
MOLECULAR EPIDEMIOLOGY AND CANCER PREVENTION: Protection by green tea, black tea, and indole-3-carbinol against 2-amino-3-methylimidazo[4,5-f]quinoline-induced DNA adducts and colonic aberrant crypts in the F344 rat
Mei-Rong Xu, A. C. Bailey, J. Hernaez, C. Taoka +2 more
1996152 citations Open access
Semantic Scholar
Comparative carcinogenicity in A/J mice and metabolism by cultured mouse peripheral lung of N'-nitrosonornicotine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, and their analogues.
A. Castonguay, D. Lin, G. Stoner, P. Radok +4 more
1983Cancer Research150 citations
Semantic Scholar
Chemoprevention of oral cancer by black raspberries.
B. Casto, L. Kresty, Carrie L Kraly, D. Pearl +5 more
2002Anticancer Research130 citations
Semantic Scholar
Protection by chlorophyllin and indole-3-carbinol against 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced DNA adducts and colonic aberrant crypts in the F344 rat.
D. Guo, H. Schut, Cindy D. Davis, Elizabeth G. Snyderwine +2 more
1995Carcinogenesis127 citations
Semantic Scholar
Metabolism of tobacco-specific N-nitrosamines by cultured human tissues.
A. Castonguay, G. Stoner, H. Schut, S. Hecht
1983Proceedings of the National Academy of Sciences of the United States of America109 citations Open access
Semantic Scholar
Prevention by aspirin and its combination with alpha-difluoromethylornithine of azoxymethane-induced tumors, aberrant crypt foci and prostaglandin E2 levels in rat colon.
Hong Li, H. Schut, Philip B. Conran, P. M. Kramer +5 more
1999Carcinogenesis102 citations
Semantic Scholar
Mutagenic activation of N-hydroxy-2-acetylaminofluorene in the Salmonella test system: the role of deacetylation by liver and kidney fractions from mouse and rat.
H. Schut, P. Wirth, S. Thorgeirsson
1978Molecular Pharmacology92 citations
Semantic Scholar
Novel LC-ESI/MS/MS(n) method for the characterization and quantification of 2'-deoxyguanosine adducts of the dietary carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by 2-D linear quadrupole ion trap mass spectrometry.
Angela K. Goodenough, H. Schut, R. Turesky
2007Chemical Research in Toxicology81 citations Open access
Semantic Scholar
Enzymatic phase II activation of the N-hydroxylamines of IQ, MeIQx and PhIP by various organs of monkeys and rats.
Cindy D. Davis, H. Schut, Elizabeth G. Snyderwine
1993Carcinogenesis78 citations
Semantic Scholar
32P-postlabeling analysis of IQ, MeIQx and PhIP adducts formed in vitro in DNA and polynucleotides and found in vivo in hepatic DNA from IQ-, MeIQx- and PhIP-treated monkeys.
Elizabeth G. Snyderwine, Cindy D. Davis, K. Nouso, P. Roller +1 more
1993Carcinogenesis71 citations
Semantic Scholar
N-Acetyltransferase expression and DNA binding of N-hydroxyheterocyclic amines in human prostate epithelium.
Ching Y. Wang, M. Debiec-Rychter, H. Schut, P. Morse +4 more
1999Carcinogenesis68 citations
Semantic Scholar
Indole-3-carbinol as a chemopreventive agent in 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) carcinogenesis: inhibition of PhIP-DNA adduct formation, acceleration of PhIP metabolism, and induction of cytochrome P450 in female F344 rats.
Ying-Hui He, M. Friesen, R. Ruch, H. Schut
2000Food and Chemical Toxicology62 citations
Semantic Scholar
Mutagenic activation of IQ, PhIP and MeIQx by hepatic microsomes from rat, monkey and man: low mutagenic activation of MeIQx in cynomolgus monkeys in vitro reflects low DNA adduct levels in vivo.
Cindy D. Davis, H. Schut, R. H. Adamson, Unnur P. Thorgeirsson +2 more
1993Carcinogenesis59 citations
Semantic Scholar
Metabolism of food-derived heterocyclic amines in nonhuman primates.
Elizabeth G. Snyderwine, Robert J. Turesky, K. Turteltaub, Cindy D. Davis +7 more
1997Mutation research56 citations
Semantic Scholar
Possible mechanisms for PhIP-DNA adduct formation in the mammary gland of female Sprague-Dawley rats.
Amit Ghoshal, Cindy D. Davis, H. Schut, E. Snyderwine
1995Carcinogenesis51 citations
Semantic Scholar
Metabolism and DNA binding of benzo[a]pyrene in cultured human bladder and bronchus.
Gary D. Stoner, F. Daniel, K. Schenck, H. Schut +2 more
1982Carcinogenesis51 citations
Semantic Scholar
DNA adduct formation of the carcinogen 2-amino-3-methylimidazo[4,5-f]-quinoline in target tissues of the F-344 rat.
H. Schut, K. Putman, K. Randerath
1988Cancer Letters50 citations
Semantic Scholar
Lobe-specific increases in malondialdehyde DNA adduct formation in the livers of mice following infection with Helicobacter hepaticus.
Rajinder Singh, Chiara Leuratti, Shylaja Josyula, M. Sipowicz +6 more
2001Carcinogenesis48 citations
Semantic Scholar
Inhibition of 2-amino-3-methylimidazo[4,5-f]quinoline-DNA adduct formation in CDF1 mice by heat-altered derivatives of linoleic acid.
Hong-Xiang Zu, H. Schut
1992Food and Chemical Toxicology47 citations
Semantic Scholar
Tea as a Potential Chemopreventive Agent in PhIP Carcinogenesis: Effects of Green Tea and Black Tea on PhIP-DNA Adduct Formation in Female F-344 Rats
H. Schut, R. Yao
2000Nutrition and Cancer45 citations
Semantic Scholar
Mutagenic specificity of 2-amino-3-methylimidazo[4,5-f]quinoline and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine in the supF shuttle vector system.
H. Endo, H. Schut, Elizabeth G. Snyderwine
1994Cancer Research44 citations
Semantic Scholar
Metabolic processing and carcinogenicity of heterocyclic amines in nonhuman primates.
R. H. Adamson, E. G. Snyderwine, U. Thorgeirsson, H. Schut +4 more
1990Princess Takamatsu symposia42 citations
Semantic Scholar
A comparison of the lung adenoma response in strain A/J mice after intraperitoneal and oral administration of carcinogens.
Gary D. Stoner, E. Greisiger, H. Schut, Michael A. Pereira +3 more
1984Toxicology and Applied Pharmacology42 citations
Semantic Scholar
In vitro metabolism and mutagenic activation of 2-acetylaminofluorene by subcellular liver fractions from Cotton rats.
H. Schut, S. Thorgeirsson
1978Cancer Research42 citations
Semantic Scholar
Interspecies comparisons of benzo(a)pyrene metabolism and DNA-adduct formation in cultured human and animal bladder and tracheobronchial tissues.
F. Daniel, H. Schut, David W. Sandwisch, K. Schenck +3 more
1983Cancer Research41 citations
Semantic Scholar
Deficiency in N-acetylgalactosamine-6-sulfate sulfatase results in collagen perturbations in cartilage of Morquio syndrome A patients.
R. Bank, J. Groener, J. V. van Gemund, Petra D Maaswinkel +3 more
2009Molecular Genetics and Metabolism40 citations
Semantic Scholar
Cytotoxicity, DNA adduct formation and DNA repair induced by 2-hydroxyamino-3-methylimidazo[4,5-f]quinoline and 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in cultured human mammary epithelial cells.
L. Fan, H. Schut, Elizabeth G. Snyderwine
1995Carcinogenesis37 citations
Semantic Scholar
DNA adducts in humans as dosimeters of exposure to environmental, occupational, or dietary genotoxins 1
H. Schut, K. Shiverick
1992The FASEB Journal37 citations
Semantic Scholar
DNA binding and adduct formation of aflatoxin B1 in cultured human and animal tracheobronchial and bladder tissues.
Gary D. Stoner, F. Daniel, K. Schenck, H. Schut +2 more
1982Carcinogenesis36 citations
Semantic Scholar
Inhibition of 2-amino-3-methylimidazo[4,5-f]quinoline-DNA adducts by indole-3-carbinol: dose-response studies in the rat colon.
Mei-Rong Xu, H. Schut, L. Bjeldanes, David E. Williams +2 more
1997Carcinogenesis35 citations
Semantic Scholar
Chemopreventive properties of Indole‐3‐Carbinol (I3C): Inhibition of DNA adduct formation of the dietary carcinogen, 2‐Amino‐1‐Methyl‐6‐Phenylimidazo [4,5‐b]Pyridine (PhIP), in female F344 rats
Ying-Hui He, Maarten H. E. Smale, H. Schut
1997Journal of cellular biochemistry. Supplement33 citations
Semantic Scholar
Inhibition of Chemically Induced Carcinogenesis by Citrus Limonoids
Lu-Ke K. T. Lam, Jian Zhang, S. Hasegawa, H. Schut
199433 citations
Semantic Scholar
Intestinal tumorigenesis in multiple intestinal neoplasia mice induced by the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine: perinatal susceptibility, regional variation, and correlation with DNA adducts.
I. Steffensen, H. Schut, J. Paulsen, Å. Andreassen +1 more
2001Cancer Research32 citations
Semantic Scholar
Susceptibility of rats to mammary gland carcinogenesis by the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) varies with age and is associated with the induction of differential gene expression.
Shan Liang, Minshu Yu, H. Schut, E. Snyderwine
2004American Journal of Pathology31 citations Open access
Semantic Scholar
DNA adduct levels of 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine (PhIP) in tissues of cynomolgus monkeys after single or multiple dosing.
E. Snyderwine, H. Schut, T. Sugimura, M. Nagao +1 more
1994Carcinogenesis31 citations
Semantic Scholar
Metabolism and DNA adduct formation of 2-acetylaminofluorene by bladder explants from human, dog, monkey, hamster and rat.
H. Schut, F. Daniel, K. Schenck, Timothy R. Loeb +1 more
1984Carcinogenesis31 citations
Semantic Scholar
Removal of DNA adducts of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in the male Fischer-344 rat.
David A. Cummings, H. Schut
1994Carcinogenesis30 citations
Semantic Scholar
Proliferation, development and DNA adduct levels in the mammary gland of rats given 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine and a high fat diet.
Elizabeth G. Snyderwine, Cindy D. Davis, H. Schut, S. Roberts-Thomson
1998Carcinogenesis29 citations
Semantic Scholar
Similar patterns of DNA adduct formation of 2-amino-3-methylimidazo [4,5-f]quinoline in the Fischer 344 rat, CDF1 mouse, cynomolgus monkey and Salmonella typhimurium.
H. Schut, E. G. Snyderwine, Hong-Xiang Zu, S. Thorgeirsson
1991Carcinogenesis27 citations
Semantic Scholar
Validation in rats of two biomarkers of exposure to the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP): PhIP-DNA adducts and urinary PhIP.
M. Friesen, David A. Cummings, L. Garren, Ross Butler +2 more
1996Carcinogenesis24 citations
Semantic Scholar
Effects of dietary conjugated linoleic acid on DNA adduct formation of PhIP and IQ after bolus administration to female F344 rats.
Shylaja Josyula, H. Schut
1998Nutrition and Cancer22 citations
Semantic Scholar
Loss of heterozygosity on chromosomes 1, 11, 12, and 14 in hybrid mouse lung adenocarcinomas
C. R. Herzog, Bin Chen, Yian Wang, H. Schut +1 more
1996Molecular Carcinogenesis19 citations
Semantic Scholar
Preliminary investigations of tissue specificity, species specificity, and strategies for identifying chemicals causing DNA adducts in human placenta.
R. Everson, E. Randerath, T. A. Avitts, H. Schut +1 more
1987Progress in experimental tumor research19 citations
Semantic Scholar
In vivo mutagenicity and hepatocarcinogenicity of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx) in bitransgenic c-myc/lambda lacZ mice.
Doug-Young Ryu, Valerie S. W. Pratt, Cindy D. Davis, H. Schut +1 more
1999Cancer Research18 citations
Semantic Scholar
Inhibition of DNA adduct formation of 2‐amino‐1‐methyl‐6‐phenylimidazo[4,5‐b]pyridine and 2‐amino‐3‐methylimidazo[4,5‐f]quinoline by dietary indole‐3‐carbinol in female rats
Ying-Hui He, H. Schut
1999Journal of biochemical and molecular toxicology18 citations
Semantic Scholar
Cytochrome P4501A2 constitutively expressed from transduced DNA mediates metabolic activation and DNA‐adduct formation of aromatic amine carcinogens in NIH 3T3 cells
N. Battula, H. Schut, S. Thorgeirsson
1991Molecular Carcinogenesis18 citations
Semantic Scholar
Activation of aminoimidazole carcinogens by nitrosation: mutagenicity and nucleotide adducts
T. Zenser, V. Lakshmi, H. Schut, Hui-jia Zhou +1 more
2009Mutation research17 citations Open access
Semantic Scholar
Oestrogen formation from C19 precursors in human choriocarcinoma in culture.
H. Schut, J. D. Townsley
1977Acta Endocrinologica17 citations
Semantic Scholar

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Cindy D. Davis×8
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Cindy D. Davis — researcher profile on SciRah
Elizabeth G. Snyderwine×8
S. Thorgeirsson×6
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S. Thorgeirsson — researcher profile on SciRah
E. Snyderwine×5
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E. Snyderwine — researcher profile on SciRah
R. Dashwood×4
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R. Dashwood — researcher profile on SciRah

Gary D. Stoner×4

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Gary D. Stoner — researcher profile on SciRah

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F. Daniel — researcher profile on SciRah

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K. Schenck — researcher profile on SciRah

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G. Stoner — researcher profile on SciRah

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Ying-Hui He — researcher profile on SciRah

R. H. Adamson×3

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R. H. Adamson — researcher profile on SciRah

David W. Sandwisch×3