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T. Zenser · SciRah

Researcher profile · Semantic Scholar

T. Zenser

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T. Zenser — researcher profile on SciRah

h-index: 38
Works: 214
Citations: 5,009

Most-cited papers

The impact of interindividual variation in NAT2 activity on benzidine urinary metabolites and urothelial DNA adducts in exposed workers.
N. Rothman, V. Bhatnagar, R. Hayes, T. Zenser +13 more
1996Proceedings of the National Academy of Sciences of the United States of America85 citations Open access
Semantic Scholar
Human N-acetylation of benzidine: role of NAT1 and NAT2.
T. Zenser, V. Lakshmi, T. Rustan, M. Doll +3 more
1996Cancer Research84 citations
Semantic Scholar
Glucuronidation of benzidine and its metabolites by cDNA-expressed human UDP-glucuronosyltransferases and pH stability of glucuronides.
Marco Ciotti, V. Lakshmi, N. K. Basu, Bernard B. Davis +2 more
1999Carcinogenesis69 citations Open access
Semantic Scholar
Mechanism of formation and structural characterization of DNA adducts derived from peroxidative activation of benzidine.
Y. Yamazoe, T. Zenser, Dwight W. Miller, F. Kadlubar
1988Carcinogenesis65 citations
Semantic Scholar
Inhibition by aspirin of N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide initiation and sodium saccharin promotion of urinary bladder carcinogenesis in male F344 rats.
T. Sakata, R. Hasegawa, S. Johansson, T. Zenser +1 more
1986Cancer Research61 citations
Semantic Scholar
Acidic urine pH is associated with elevated levels of free urinary benzidine and N-acetylbenzidine and urothelial cell DNA adducts in exposed workers.
N. Rothman, Glenn Talaska, Richard B. Hayes, V. Bhatnagar +11 more
1997Cancer Epidemiology, Biomarkers and Prevention56 citations
Semantic Scholar
Glucuronide conjugates of 4-aminobiphenyl and its N-hydroxy metabolites. pH stability and synthesis by human and dog liver.
S. R. Babu, V. Lakshmi, George W. Huang, T. Zenser +1 more
1996Biochemical Pharmacology54 citations
Semantic Scholar
Human and Escherichia coli β-Glucuronidase Hydrolysis of Glucuronide Conjugates of Benzidine and 4-Aminobiphenyl, and their Hydroxy Metabolites
T. Zenser, V. Lakshmi, Bernard B. Davis
1999Drug Metabolism And Disposition53 citations
Semantic Scholar
Metabolism of N-acetylbenzidine and initiation of bladder cancer.
T. Zenser, V. Lakshmi, Fong-Fu Hsu, B. Davis
2002Mutation research50 citations
Semantic Scholar
Eicosanoid synthesis by cultured human urothelial cells: potential role in bladder cancer.
A. Danon, T. Zenser, David L. Thomasson, Bernard B. Davis
1986Cancer Research42 citations
Semantic Scholar
The glutathione S-transferase M1 (GSTM1) null genotype and benzidine-associated bladder cancer, urine mutagenicity, and exfoliated urothelial cell DNA adducts.
N. Rothman, Richard B. Hayes, T. Zenser, D. DeMarini +19 more
1996Cancer Epidemiology, Biomarkers and Prevention41 citations
Semantic Scholar
Glucuronidation of N-hydroxy metabolites of N-acetylbenzidine.
S. R. Babu, V. Lakshmi, F. Hsu, T. Zenser +1 more
1995Carcinogenesis39 citations
Semantic Scholar
N-acetylbenzidine and N,N'-diacetylbenzidine formation by rat and human liver slices exposed to benzidine.
V. Lakshmi, Douglas A. Bell, M. Watson, T. Zenser +1 more
1995Carcinogenesis39 citations
Semantic Scholar
N-glucuronidation of benzidine and its metabolites. Role in bladder cancer.
T. Zenser, V. Lakshmi, B. Davis
1998Drug Metabolism And Disposition38 citations
Semantic Scholar
Urinary mutagenicity as a biomarker in workers exposed to benzidine: correlation with urinary metabolites and urothelial DNA adducts.
D. DeMarini, L. Brooks, V. Bhatnagar, Richard B. Hayes +13 more
1997Carcinogenesis37 citations
Semantic Scholar
Determination of benzidine, N-acetylbenzidine, and N,N'-diacetylbenzidine in human urine by capillary gas chromatography/negative ion chemical ionization mass spectrometry.
F. Hsu, V. Lakshmi, N. Rothman, V. K. Bhatnager +7 more
1996Analytical Biochemistry33 citations
Semantic Scholar
Myeloperoxidase Potentiates Nitric Oxide-mediated Nitrosation*
V. Lakshmi, W. Nauseef, T. Zenser
2005Journal of Biological Chemistry29 citations Open access
Semantic Scholar
Rat liver cytochrome P450 metabolism of N-acetylbenzidine and N,N'-diacetylbenzidine.
V. Lakshmi, T. Zenser, Bernard B. Davis
1997Drug Metabolism And Disposition29 citations
Semantic Scholar
Role of N-glucuronidation in benzidine-induced bladder cancer in dog.
S. R. Babu, V. Lakshmi, F.-F. Hsu, T. Zenser +1 more
1992Carcinogenesis29 citations
Semantic Scholar
N-acetylbenzidine-N'-glucuronidation by human, dog and rat liver.
S. R. Babu, V. Lakshmi, F.-F. Hsu, R. E. Kane +2 more
1993Carcinogenesis26 citations
Semantic Scholar
The effect of long-term administration of aspirin and sodium saccharin on the rat kidney.
S. Johansson, T. Sakata, R. Hasegawa, T. Zenser +2 more
1986Toxicology and Applied Pharmacology26 citations
Semantic Scholar
The role of acetylation in benzidine metabolism and DNA adduct formation in dog and rat liver.
V. Lakshmi, T. Zenser, H. D. Goldman, G. Spencer +3 more
1995Chemical Research in Toxicology25 citations
Semantic Scholar
Nitrating reactive nitric oxygen species transform acetaminophen to 3-nitroacetaminophen.
V. Lakshmi, F. Hsu, Bernard B. Davis, T. Zenser
2000Chemical Research in Toxicology23 citations
Semantic Scholar
Metabolism and disposition of benzidine in the dog.
V. Lakshmi, M. Mattammal, Leslie A. Spry, F. Kadlubar +2 more
1990Carcinogenesis23 citations
Semantic Scholar
Hemin potentiates nitric oxide-mediated nitrosation of 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) to 2-nitrosoamino-3-methylimidazo[4,5-f]quinoline.
V. Lakshmi, M. Clapper, Wen-Chi L. Chang, T. Zenser
2005Chemical Research in Toxicology22 citations
Semantic Scholar
Nitric oxide-mediated nitrosation of 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline potentiated by hemin and myeloperoxidase.
V. Lakshmi, F. Hsu, T. Zenser
2005Chemical Research in Toxicology21 citations
Semantic Scholar
Characteristics of bradykinin and TPA increases in the PGE2 levels of human urothelial cells.
T. Zenser, D. Thomasson, B. Davis
1988Carcinogenesis20 citations
Semantic Scholar
Transformation and activation of benzidine by oxidants of the inflammatory response.
V. Lakshmi, Fong-Fu Hsu, T. Zenser
2003Chemical Research in Toxicology19 citations
Semantic Scholar
Glucuronidation of N-acetylbenzidine by human liver.
S. R. Babu, V. Lakshmi, T. Zenser, Bernard B. Davis
1994Drug Metabolism And Disposition19 citations
Semantic Scholar
N'-(3'-monophospho-deoxyguanosin-8-yl)-N-acetylbenzidine formation by peroxidative metabolism.
V. Lakshmi, T. Zenser, Bernard B. Davis
1998Carcinogenesis18 citations Open access
Semantic Scholar
Mechanism of 3-(glutathion-S-yl)-benzidine formation.
V. Lakshmi, T. Zenser, Bernard B. Davis
1994Toxicology and Applied Pharmacology18 citations
Semantic Scholar
Peroxidatic metabolism of benzidine by intact tissue: a prostaglandin H synthase-mediated process.
Ronald W. Wise, T. Zenser, John R. Rice, Bernard B. Davis
1986Carcinogenesis18 citations
Semantic Scholar
Activation of aminoimidazole carcinogens by nitrosation: mutagenicity and nucleotide adducts
T. Zenser, V. Lakshmi, H. Schut, Hui-jia Zhou +1 more
2009Mutation research17 citations Open access
Semantic Scholar
Metabolism of a Heterocyclic Amine Colon Carcinogen in Young and Old Rats
H. Armbrecht, V. Lakshmi, Jason Wickstra, Fong-Fu Hsu +1 more
2007Drug Metabolism And Disposition17 citations
Semantic Scholar
N-Demethylation Is a Major Route of 2-Amino-3-Methylimidazo[4,5-f]quinoline Metabolism in Mouse
V. Lakshmi, F. Hsu, T. Zenser
2008Drug Metabolism And Disposition16 citations Open access
Semantic Scholar
2-Nitrosoamino-3-methylimidazo[4,5-f]quinoline activated by the inflammatory response forms nucleotide adducts.
V. Lakshmi, H. Schut, T. Zenser
2005Food and Chemical Toxicology16 citations
Semantic Scholar
Lung prostaglandin H synthase and mixed-function oxidase metabolism of nicotine.
M. Mattammal, V. Lakshmi, T. Zenser, B. Davis
1987Journal of Pharmacology and Experimental Therapeutics16 citations
Semantic Scholar
Peroxygenase Metabolism of N-Acetylbenzidine by Prostaglandin H Synthase
T. Zenser, V. Lakshmi, F. Hsu, B. Davis
1999Journal of Biological Chemistry14 citations Open access
Semantic Scholar
Human liver glucuronidation of benzidine.
S. R. Babu, V. Lakshmi, Ida S. Owens, T. Zenser +1 more
1994Carcinogenesis13 citations
Semantic Scholar
Regulation of dog urothelial cell arachidonic acid release and prostaglandin E2 synthesis.
Y. Wong, T. Zenser, B. Davis
1989Carcinogenesis13 citations
Semantic Scholar
NADPH-dependent oxidation of benzidine by rat liver.
V. Lakshmi, Nathan T. Zenser, F.-F. Hsu, M. Mattammal +2 more
1996Carcinogenesis12 citations Open access
Semantic Scholar
Effect of peroxidase inhibitors on an in vivo metabolite of the urinary bladder carcinogen N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide in rats.
John R. Rice, Leslie A. Spry, T. Zenser, Bernard B. Davis
1988Cancer Research12 citations
Semantic Scholar
Stability and reactivity of 2-nitrosoamino-3,8-dimethylimidazo[4,5-f]quinoxaline.
V. Lakshmi, Fong-Fu Hsu, H. Schut, T. Zenser
2006Chemical Research in Toxicology11 citations Open access
Semantic Scholar
N-Acetylbenzidine-DNA adduct formation by phorbol 12-myristate-stimulated human polymorphonuclear neutrophils.
V. Lakshmi, Fong-Fu Hsu, Bernard B. Davis, T. Zenser
2000Chemical Research in Toxicology11 citations
Semantic Scholar
Benzidine glucuronidation in dog liver.
S. R. Babu, V. Wongsurawat, T. Zenser, Bernard B. Davis
1993Carcinogenesis11 citations
Semantic Scholar
Mechanism of peroxidative activation of the bladder carcinogen 2-amino-4-(5-nitro-2-furyl)-thiazole (ANFT): comparison with benzidine.
V. Lakshmi, M. Mattammal, T. Zenser, Bernard B. Davis
1990Carcinogenesis10 citations
Semantic Scholar
Nitrosation and nitration of 2-amino-3-methylimidazo[4,5-f]quinoline by reactive nitrogen oxygen species.
V. Lakshmi, Fong-Fu Hsu, T. Zenser
2002Chemical Research in Toxicology9 citations
Semantic Scholar
Methemoglobin oxidation of N-acetylbenzidine to form a sulfinamide.
T. Zenser, V. Lakshmi, F. Hsu, Bernard B. Davis
2001Drug Metabolism And Disposition9 citations
Semantic Scholar
Metabolism and disposition of bladder carcinogens in rat and guinea pig: possible mechanism of guinea pig resistance to bladder cancer.
R. Dawley, T. Zenser, M. Mattammal, V. Lakshmi +2 more
1991Cancer Research9 citations
Semantic Scholar
Mechanism of 12-O-tetradecanoylphorbol-13-acetate enhanced metabolism of arachidonic acid in dog urothelial cells.
T. Zenser, T. Eling, Z. Duniec, Y. Wong +1 more
1990Cancer Research9 citations
Semantic Scholar

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V. Lakshmi×40
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Bernard B. Davis×21
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F. Hsu×9
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B. Davis×9
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Bernard B. Davis×8

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S. Kashyap — researcher profile on SciRah

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D. J. Parikh×5

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M. Mattammal×5

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V. Bhatnagar×4

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