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R. Dashwood · SciRah

Researcher profile · Semantic Scholar

R. Dashwood

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R. Dashwood — researcher profile on SciRah

h-index: 68
Works: 283
Citations: 15K

Most-cited papers

Streptococcus gallolyticus subsp. gallolyticus promotes colorectal tumor development
Ritesh Kumar, Jennifer L. Herold, D. Schady, Jennifer S. Davis +12 more
2017PLoS Pathogens212 citations Open access
Semantic Scholar
Absorption and chemopreventive targets of sulforaphane in humans following consumption of broccoli sprouts or a myrosinase-treated broccoli sprout extract
L. L. Atwell, Anna Hsu, C. Wong, J. Stevens +9 more
2015Molecular Nutrition & Food Research128 citations Open access
Semantic Scholar
HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates
Praveen Rajendran, Ariam I. Kidane, Tian-Shu Yu, W. Dashwood +5 more
2013Epigenetics118 citations Open access
Semantic Scholar
HETEROGENEOUS REACTIONS OF PM-BOUND PAHs AND NPAHs WITH NO3/N2O5, OH RADICALS, AND O3 UNDER SIMULATED LONG-RANGE ATMOSPHERIC TRANSPORT CONDITIONS: REACTIVITY AND MUTAGENICITY
N. Jariyasopit, K. Zimmermann, Jill E. Schrlau, J. Arey +5 more
2014Environmental Science and Technology109 citations Open access
Semantic Scholar
Effects of Sulforaphane and 3,3′-Diindolylmethane on Genome-Wide Promoter Methylation in Normal Prostate Epithelial Cells and Prostate Cancer Cells
C. Wong, Anna Hsu, Alex Buchanan, Zoraya Palomera-Sanchez +5 more
2014PLoS ONE109 citations Open access
Semantic Scholar
Epigenetic Regulation of NRF2/KEAP1 by Phytochemicals
S. Bhattacharjee, R. Dashwood
2020Antioxidants102 citations Open access
Semantic Scholar
Long non-coding RNAs and sulforaphane: a target for chemoprevention and suppression of prostate cancer
L. Beaver, Rachael Kuintzle, Alex Buchanan, M. Wiley +9 more
2017Journal of Nutritional Biochemistry92 citations Open access
Semantic Scholar
Reliable tumor detection by whole-genome methylation sequencing of cell-free DNA in cerebrospinal fluid of pediatric medulloblastoma
Jia Li, Si-Bo Zhao, Minjung Lee, Yue Yin +10 more
2020Science Advances78 citations Open access
Semantic Scholar
HDAC8 and STAT3 repress BMF gene activity in colon cancer cells
Yu-ming Kang, Nian Hui, Praveen Rajendran, Eunah Kim +10 more
2014Cell Death and Disease76 citations Open access
Semantic Scholar
Histone and Non-Histone Targets of Dietary Deacetylase Inhibitors
Eunah Kim, W. Bisson, C. Löhr, David E. Williams +3 more
2015Current Topics in Medicinal Chemistry75 citations Open access
Semantic Scholar
Phytochemicals from Cruciferous Vegetables, Epigenetics, and Prostate Cancer Prevention
Gregory W. Watson, L. Beaver, David E. Williams, R. Dashwood +1 more
2013AAPS Journal75 citations Open access
Semantic Scholar
Sulforaphane Bioavailability and Chemopreventive Activity in Men Presenting for Biopsy of the Prostate Gland: A Randomized Controlled Trial
Zhenzhen Zhang, M. Garzotto, E. Davis, M. Mori +10 more
2019Nutrition and Cancer71 citations Open access
Semantic Scholar
Novel Nitro-PAH Formation from Heterogeneous Reactions of PAHs with NO2, NO3/N2O5, and OH Radicals: Prediction, Laboratory Studies and Mutagenicity
N. Jariyasopit, Melissa MC Intosh, K. Zimmermann, J. Arey +6 more
2013Environmental Science and Technology71 citations Open access
Semantic Scholar
Nrf2 status affects tumor growth, HDAC3 gene promoter associations, and the response to sulforaphane in the colon
Praveen Rajendran, W. Dashwood, Li Li, Yu-Hua Kang +9 more
2015Clinical Epigenetics69 citations Open access
Semantic Scholar
Epigenetic Regulation by Sulforaphane: Opportunities for Breast and Prostate Cancer Chemoprevention
L. L. Atwell, L. Beaver, J. Shannon, David E. Williams +2 more
2015Current Pharmacology Reports68 citations Open access
Semantic Scholar
Heterocyclic Analogs of Sulforaphane Trigger DNA Damage and Impede DNA Repair in Colon Cancer Cells: Interplay of HATs and HDACs
Adaobi O. Okonkwo, J. Mitra, G. Johnson, Li Li +5 more
2018Molecular Nutrition & Food Research56 citations Open access
Semantic Scholar
Matrix metalloproteinase 7 contributes to intestinal barrier dysfunction by degrading tight junction protein Claudin-7
Ying Xiao, Hai-Feng Lian, X. Zhong, S. Krishnachaitanya +6 more
2022Frontiers in Immunology54 citations Open access
Semantic Scholar
A role for low-abundance miRNAs in colon cancer: the miR-206/Krüppel-like factor 4 (KLF4) axis
M. Parasramka, W. Dashwood, Rong Wang, Hassaan Saeed +3 more
2012Clinical Epigenetics54 citations Open access
Semantic Scholar
A functional pseudogene, NMRAL2P, is regulated by Nrf2 and serves as a co-activator of NQO1 in sulforaphane-treated colon cancer cells
G. Johnson, Jia Li, L. Beaver, W. Dashwood +5 more
2017Molecular Nutrition & Food Research47 citations Open access
Semantic Scholar
Epigenetic inactivation of endothelin-2 (ET-2) and ET-3 in colon cancer
Rong Wang, C. Löhr, Kay A. Fischer, W. Dashwood +6 more
2012International Journal of Cancer47 citations Open access
Semantic Scholar
The role of microRNA in nutritional control
E. N. Nolte-'t Hoen, E. van Rooij, M. Bushell, C.-Y. Zhang +4 more
2015Journal of Internal Medicine40 citations Open access
Semantic Scholar
Measuring Histone Deacetylase Inhibition in the Brain
D. Reddy, Xin Wu, Victoria M. Golub, W. Dashwood +1 more
2018Current Protocols in Pharmacology37 citations Open access
Semantic Scholar
MicroRNA profiling of carcinogen-induced rat colon tumors and the influence of dietary spinach
M. Parasramka, W. Dashwood, Rong Wang, A. Abdelli +4 more
2012Molecular Nutrition & Food Research36 citations Open access
Semantic Scholar
Acetylation of CCAR2 establishes a BET/BRD9 acetyl switch in response to combined deacetylase and bromodomain inhibition
Praveen Rajendran, G. Johnson, Li Li, Ying-Shiuan Chen +17 more
2019Cancer Research35 citations Open access
Semantic Scholar
3,3′-Diindolylmethane Induces G1 Arrest and Apoptosis in Human Acute T-Cell Lymphoblastic Leukemia Cells
Lyndsey E. Shorey, A. Hagman, David E. Williams, E. Ho +2 more
2012PLoS ONE34 citations Open access
Semantic Scholar
Transcriptome analysis reveals a dynamic and differential transcriptional response to sulforaphane in normal and prostate cancer cells and suggests a role for Sp1 in chemoprevention
L. Beaver, Alex Buchanan, Elizabeth I. Sokolowski, Allison N. Riscoe +6 more
2014Molecular Nutrition & Food Research32 citations Open access
Semantic Scholar
Untargeted metabolomic screen reveals changes in human plasma metabolite profiles following consumption of fresh broccoli sprouts
Lauren M. Housley, A. A. Magaña, Anna Hsu, L. Beaver +10 more
2018Molecular Nutrition & Food Research30 citations Open access
Semantic Scholar
SUV39H1/H3K9me3 attenuates sulforaphane-induced apoptotic signaling in PC3 prostate cancer cells
Gregory W. Watson, S. Wickramasekara, Z. Palomera‐Sanchez, C. Black +4 more
2014Oncogenesis30 citations Open access
Semantic Scholar
Emerging crosstalk between long non-coding RNAs and Nrf2 signaling
S. Bhattacharjee, Jia Li, R. Dashwood
2020Cancer Letters29 citations Open access
Semantic Scholar
Neonatal Colonic Inflammation Epigenetically Aggravates Epithelial Inflammatory Responses to Injury in Adult Life
X. Zhong, J. Winston, Xiuju Luo, K. Kline +6 more
2018Cellular and Molecular Gastroenterology and Hepatology28 citations Open access
Semantic Scholar
Differential modulation of dibenzo[def,p]chrysene transplacental carcinogenesis: Maternal diets rich in indole-3-carbinol versus sulforaphane
Lyndsey E. Shorey, E. Madeen, L. L. Atwell, E. Ho +4 more
2013Toxicology and Applied Pharmacology28 citations Open access
Semantic Scholar
The Epigenome as a Potential Mediator of Cancer Prevention by Dietary Phytochemicals: the Fetus as a Target
P. Kaur, Lyndsey E. Shorey, E. Ho, R. Dashwood +1 more
2013Nutrition reviews26 citations Open access
Semantic Scholar
Dietary spinach reshapes the gut microbiome in an Apc-mutant genetic background: mechanistic insights from integrated multi-omics
Ying-Shiuan Chen, Jia Li, Rani Menon, A. Jayaraman +6 more
2021Gut microbes25 citations Open access
Semantic Scholar
CCAR1 and CCAR2 as gene chameleons with antagonistic duality: Preclinical, human translational, and mechanistic basis
G. Johnson, Praveen Rajendran, R. Dashwood
2020Cancer Science25 citations Open access
Semantic Scholar
Reciprocal regulation of BMF and BIRC5 (Survivin) linked to Eomes overexpression in colorectal cancer
Rong Wang, Yu-Hua Kang, C. Löhr, Kay A. Fischer +6 more
2016Cancer Letters25 citations Open access
Semantic Scholar
Broccoli sprouts delay prostate cancer formation and decrease prostate cancer severity with a concurrent decrease in HDAC3 protein expression in TRAMP mice.
L. Beaver, C. Löhr, John D. Clarke, Sarah T Glasser +8 more
201724 citations Open access
Semantic Scholar
Neonatal injury increases gut permeability by epigenetically suppressing E-cadherin in adulthood
K. Kline, Hai-Feng Lian, X. Zhong, Xiu-Ju Luo +6 more
2019Journal of Immunology22 citations Open access
Semantic Scholar
p53-dependent autophagic degradation of TET2 modulates cancer therapeutic resistance
Jixiang Zhang, Peng Tan, Lei Guo, Jing Gong +13 more
2018Oncogene22 citations Open access
Semantic Scholar
The phytochemical 3,3′-Diindolylmethane decreases expression of AR-controlled DNA damage repair genes through repressive chromatin modifications and is associated with DNA damage in prostate cancer cells
Z. Palomera‐Sanchez, Gregory W. Watson, C. Wong, L. Beaver +3 more
2017Journal of Nutritional Biochemistry19 citations Open access
Semantic Scholar
Broccoli Sprouts Delay Prostate Cancer Formation and Decrease Prostate Cancer Severity with a Concurrent Decrease in HDAC3 Protein Expression in Transgenic Adenocarcinoma of the Mouse Prostate (TRAMP) Mice
L. Beaver, C. Löhr, John D. Clarke, Sarah T Glasser +8 more
2017Current Developments in Nutrition18 citations Open access
Semantic Scholar
A hypermorphic epithelial β-catenin mutation facilitates intestinal tumorigenesis in mice in response to compounding WNT-pathway mutations
Michael Buchert, F. Rohde, M. Eissmann, N. Tebbutt +11 more
2015Disease Models & Mechanisms18 citations Open access
Semantic Scholar
Immunohistochemical characterization of intestinal neoplasia in zebrafish Danio rerio indicates epithelial origin.
Colleen E Paquette, M. Kent, T. S. Peterson, Rong Wang +2 more
2015Diseases of Aquatic Organisms17 citations Open access
Semantic Scholar
Deacetylase Plus Bromodomain Inhibition Downregulates ERCC2 and Suppresses the Growth of Metastatic Colon Cancer Cells
Sabeeta Kapoor, Trace Gustafson, Mutian Zhang, Ying-Shiuan Chen +6 more
2021Cancers15 citations Open access
Semantic Scholar
Optimization of erlotinib plus sulindac dosing regimens for intestinal cancer prevention in an Apc-mutant model of Familial Adenomatous Polyposis (FAP)
A. Uluşan, Praveen Rajendran, W. Dashwood, Omer Yavuz +8 more
2020Cancer Prevention Research15 citations Open access
Semantic Scholar
Targeting Epigenetic ‘Readers’ with Natural Compounds for Cancer Interception
E. Damiani, Munevver N. Duran, Nivedhitha Mohan, Praveen Rajendran +1 more
2020Journal of Cancer Prevention14 citations Open access
Semantic Scholar
Sulindac plus a phospholipid is effective for polyp reduction and safer than sulindac alone in a mouse model of colorectal cancer development
Jennifer S. Davis, Preeti Kanikarla‐Marie, M. Gagea, Patrick Yu +8 more
2020BMC Cancer12 citations Open access
Semantic Scholar
A miRNA signature for an environmental heterocyclic amine defined by a multi-organ carcinogenicity bioassay in the rat
Ying-Shiuan Chen, Rong Wang, W. Dashwood, C. Löhr +4 more
2017Archives of Toxicology12 citations Open access
Semantic Scholar
BRD9 Inhibition by Natural Polyphenols Targets DNA Damage/Repair and Apoptosis in Human Colon Cancer Cells
Sabeeta Kapoor, E. Damiani, Sha Wang, Ravirajan Dharmanand +5 more
2022Nutrients11 citations Open access
Semantic Scholar
Accurate quantification of PGE2 in the polyposis in rat colon (Pirc) model by surrogate analyte-based UPLC-MS/MS
Chang-Hong Yun, W. Dashwood, Lawrence N. Kwong, Song Gao +5 more
2017Journal of Pharmaceutical and Biomedical Analysis11 citations Open access
Semantic Scholar
HDAC6 activity is not required for basal autophagic flux in metastatic prostate cancer cells
Gregory W. Watson, S. Wickramasekara, Yu-Hua Fang, C. Maier +4 more
2016Experimental biology and medicine11 citations Open access
Semantic Scholar

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