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Deepak Perumal · SciRah

Researcher profile · Semantic Scholar

Deepak Perumal

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Deepak Perumal — researcher profile on SciRah

h-index: 17
Works: 62
Citations: 1,168

Most-cited papers

YAP1 REGULATES OCT4 ACTIVITY AND SOX2 EXPRESSION TO FACILITATE SELF-RENEWAL AND VASCULAR MIMICRY OF STEM-LIKE CELLS
Namrata Bora-Singhal, Jonathan Nguyen, C. Schaal, Deepak Perumal +3 more
2015Stem Cells162 citations Open access
Semantic Scholar
Stage-specific human induced pluripotent stem cells map the progression of myeloid transformation to transplantable leukemia
A. Kotini, Chan-Jung Chang, Arthur Chow, Han Yuan +19 more
2017Cell Stem Cell128 citations Open access
Semantic Scholar
Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non–Small Cell Lung Cancer
Namrata Bora-Singhal, Deepak Perumal, Jonathan Nguyen, S. Chellappan
2015Neoplasia101 citations Open access
Semantic Scholar
Mutation-Derived Neoantigen Specific T cell Responses in Multiple Myeloma
Deepak Perumal, Naoko Imai, A. Laganà, J. Finnigan +13 more
2019Clinical Cancer Research79 citations Open access
Semantic Scholar
Differential Genome Analyses of Metabolic Enzymes in Pseudomonas aeruginosa for Drug Target Identification
Deepak Perumal, C. Lim, Kishore R. Sakharkar, M. Sakharkar
2007Silico Biol.69 citations
Semantic Scholar
Subtype-specific and co-occurring genetic alterations in B-cell non-Hodgkin lymphoma
Man Chun John Ma, Saber Tadros, Alyssa Bouska, Tayla B. Heavican +32 more
2019bioRxiv65 citations Open access
Semantic Scholar
High resolution Chromatin Immunoprecipitation (ChIP) sequencing reveals novel bindings targets and prognostic role for SOX11 in Mantle cell lymphoma
Pei-Yu Kuo, V. Leshchenko, M. Fazzari, Deepak Perumal +19 more
2014Oncogene59 citations Open access
Semantic Scholar
Integrative network analysis identifies novel drivers of pathogenesis and progression in newly diagnosed multiple myeloma
A. Laganà, Deepak Perumal, D. Melnekoff, B. Readhead +14 more
2018Leukemia58 citations
Semantic Scholar
Nicotine-mediated invasion and migration of non-small cell lung carcinoma cells by modulating STMN3 and GSPT1 genes in an ID1-dependent manner
Sajith Nair, Namrata Bora-Singhal, Deepak Perumal, S. Chellappan
2014Molecular Cancer45 citations Open access
Semantic Scholar
A phase 2 study of panobinostat with lenalidomide and weekly dexamethasone in myeloma.
A. Chari, H. Cho, Amishi Dhadwal, Gillian F. Morgan +15 more
2017Blood Advances44 citations Open access
Semantic Scholar
SOX11 augments BCR signaling to drive MCL-like tumor development.
Pei-Yu Kuo, Shashidhar S. Jatiani, A. Rahman, D. Edwards +8 more
2018Blood42 citations Open access
Semantic Scholar
Nicotinic acetylcholine receptors induce c-Kit ligand/Stem Cell Factor and promote stemness in an ARRB1/ β-arrestin-1 dependent manner in NSCLC
Deepak Perumal, S. Pillai, Jonathan Nguyen, C. Schaal +2 more
2014OncoTarget40 citations Open access
Semantic Scholar
Targeting multiple targets in Pseudomonas aeruginosa PAO1 using flux balance analysis of a reconstructed genome-scale metabolic network
Deepak Perumal, Areejit Samal, Kishore R. Sakharkar, M. Sakharkar
2011Journal of drug targeting (Print)33 citations
Semantic Scholar
Dual Inhibition of CDK4/Rb and PI3K/AKT/mTOR Pathways by ON123300 Induces Synthetic Lethality in Mantle Cell Lymphomas
Saikrishna A. Divakar, M. V. Ramana Reddy, S. Cosenza, S. Baker +6 more
2015Leukemia29 citations Open access
Semantic Scholar
Precision Medicine for Relapsed Multiple Myeloma on the Basis of an Integrative Multiomics Approach
A. Laganà, I. Beno, D. Melnekoff, V. Leshchenko +15 more
2018JCO Precision Oncology27 citations Open access
Semantic Scholar
Dual Targeting of CDK4 and ARK5 Using a Novel Kinase Inhibitor ON123300 Exerts Potent Anticancer Activity against Multiple Myeloma
Deepak Perumal, Pei-Yu Kuo, V. Leshchenko, Zewei Jiang +9 more
2016Cancer Research27 citations Open access
Semantic Scholar
A Novel Five Gene Signature Derived from Stem-Like Side Population Cells Predicts Overall and Recurrence-Free Survival in NSCLC
Deepak Perumal, S. Singh, S. Yoder, G. Bloom +1 more
2012PLoS ONE26 citations Open access
Semantic Scholar
MAGE-A inhibit apoptosis and promote proliferation in multiple myeloma through regulation of BIM and p21Cip1
A. Mei, Kaity H. Tung, J. Han, Deepak Perumal +7 more
2020OncoTarget14 citations Open access
Semantic Scholar
A combined computational-experimental analyses of selected metabolic enzymes in Pseudomonas species
Deepak Perumal, Chu-Sing Lim, V. Chow, Kishore R. Sakharkar +1 more
2008International Journal on Biological Sciences12 citations Open access
Semantic Scholar
Weighted Gene Co-Expression Network Analysis (WGCNA) Identifies Highly Proliferative Myeloma Subgroup Responsive to CDK4/ARK5 Inhibition
Deepak Perumal, V. Leshchenko, Pei-Yu Kuo, Zewei Jiang +11 more
201411 citations
Semantic Scholar
A Comparative Study of Metabolic Network Topology between a Pathogenic and a Non-Pathogenic Bacterium for Potential Drug Target Identification
Deepak Perumal, Chu-Sing Lim, M. Sakharkar
2009Summit on translational bioinformatics10 citations
Semantic Scholar
In silico Identification of Putative Drug Targets in Pseudomonas aeruginosa Through Metabolic Pathway Analysis
Deepak Perumal, C. Lim, M. Sakharkar
2007Pattern Recognition in Bioinformatics10 citations Open access
Semantic Scholar
E2F1 Is a Biomarker of Selinexor Resistance in Relapsed/Refractory Multiple Myeloma Patients
A. Laganà, Seongjee Park, D. Edwards, V. Leshchenko +13 more
2018Blood9 citations Open access
Semantic Scholar
Nivolumab, Pomalidomide, and Elotuzumab Combination Regimens for Treatment of Relapsed and Refractory Multiple Myeloma: Results from the Phase 3 CheckMate 602 Study.
A. Oriol, Roman Hájek, I. Špička, I. Sandhu +12 more
2024Clinical Lymphoma, Myeloma & Leukemia8 citations
Semantic Scholar
Cloning and Targeted Disruption of Two Lipopolysaccharide Biosynthesis Genes, kdsA and waaG, of Pseudomonas aeruginosa PAO1 by Site-Directed Mutagenesis
Deepak Perumal, Kishore R. Sakharkar, Thean-Hock Tang, V. Chow +4 more
2010Journal of Molecular Microbiology and Biotechnology7 citations
Semantic Scholar
Increased HLA-E Expression Correlates with Early Relapse in Multiple Myeloma
A. Laganà, D. Ruan, D. Melnekoff, V. Leshchenko +16 more
2018Blood6 citations Open access
Semantic Scholar
MAGE-a Mediate Resistance to Chemotherapy in Multiple Myeloma through Regulation of Bcl-2 Proteins
H. Cho, A. Mei, J. Fukui, Kaity H. Tung +8 more
20166 citations
Semantic Scholar
‘Load Points’ and ‘Choke Points’ as Nodes for Prioritizing Drug Targets in Pseudomonas aeruginosa
Deepak Perumal, C. Lim, Kishore R. Sakharkar, M. Sakharkar
20096 citations
Semantic Scholar
High Dimensional Immune Profiling of Smoldering Multiple Myeloma Distinguishes Distinct Tumor Microenvironments.
Nicolas F. Fernandez, Deepak Perumal, A. Rahman, S. Kim-Schulze +6 more
2022Clinical Lymphoma, Myeloma & Leukemia5 citations
Semantic Scholar
Pathognomonic and epistatic genetic alterations in B-cell non- Pathognomonic and epistatic genetic alterations in B-cell non-Hodgkin lymphoma [preprint] Hodgkin lymphoma [preprint]
Man Chun John Ma, Saber Tadros, Alyssa Bouska, Tayla B. Heavican +34 more
20205 citations
Semantic Scholar
Pharmacokinetics and safety of subcutaneous nivolumab: results from the phase I/II CheckMate 8KX study
S. Lonardi, I. Ługowska, Anne O’Donnell, Christopher Jackson +17 more
2025Journal for ImmunoTherapy of Cancer4 citations Open access
Semantic Scholar
Nivolumab and daratumumab combination regimens for the treatment of relapsed and refractory multiple myeloma: results of a randomized phase I/II clinical trial
Al-Ola A. Abdallah, A. Lesokhin, Tomasz Wróbel, Krzysztof Jamroziak +19 more
2023Frontiers in Hematology3 citations Open access
Semantic Scholar
Pathognomonic and epistatic genetic alterations in 1 B-cell non-Hodgkin lymphoma 2
Man Chun John Ma, Saber Tadros, Alyssa Bouska, Tayla B. Heavican +34 more
20193 citations
Semantic Scholar
Single-Cell RNA Sequencing Reveals Distinct Transcriptomic Profiles of Multiple Myeloma with Implications for Personalized Medicine
D. Melnekoff, A. Laganà, Wissam Hamou, Kimaada Allette +11 more
20173 citations
Semantic Scholar
MAGE-A3 Promotes Chemotherapy Resistance and Proliferation in Multiple Myeloma through Regulation of BIM and p21Cip1
H. Cho, A. Mei, Kaity H. Tung, J. Han +7 more
2018Blood2 citations Open access
Semantic Scholar
Clonal Evolution in Newly Diagnosed Multiple Myeloma Patients: A Follow-up Study from the Mmrf Commpass Genomics Project
A. Laganà, D. Melnekoff, I. Beno, V. Leshchenko +12 more
20172 citations
Semantic Scholar
Integrative Network Analysis of Newly Diagnosed Multiple Myeloma Identifies a Novel RNA-Seq Based High Riskgene Signature
A. Laganà, Deepak Perumal, D. Melnekoff, B. Readhead +14 more
20162 citations
Semantic Scholar
Network Modeling Reveals CDC42BPA and CLEC11A As Novel Driver Genes of t(4; 14) Multiple Myeloma
Deepak Perumal, A. Laganà, D. Melnekoff, B. Readhead +13 more
20162 citations
Semantic Scholar
Microbial drug target identification using different computational approaches: Specific application to Pseudomonas aeruginosa
Deepak Perumal, C. Lim, M. Sakharkar
2008International Conference on Innovations in Information Technology2 citations
Semantic Scholar
Aberrant a-to-I RNA Editing and Prognostic Impact of Adar in Multiple Myeloma Patients with 1q Amplification
A. Laganà, Deepak Perumal, V. Leshchenko, Pei-Yu Kuo +12 more
20161 citations
Semantic Scholar
Patient-Specific Mutation-Derived Tumor Antigens As Targets for Cancer Immunotherapy in Multiple Myeloma
Deepak Perumal, A. Laganà, A. Rubinsteyn, J. Finnigan +10 more
20151 citations
Semantic Scholar
SOX11 Cooperates with CCND1 in Mantle Cell Lymphoma Pathogenesis
Pei-Yu Kuo, Zewei Jiang, Deepak Perumal, V. Leshchenko +6 more
20151 citations Open access
Semantic Scholar
Nicotine-mediated invasion and migration of non-small cell lung carcinoma cells by modulating STMN3 and GSPT1 genes in an ID1-dependent manner
Sajith Nair, Namrata Bora-Singhal, Deepak Perumal, S. Chellappan
2014Molecular Cancer1 citations Open access
Semantic Scholar
BMS-986504 in patients (pts) with advanced solid tumors with homozygous MTAP deletion ( MTAP -del): Exploratory pharmacodynamic (PD) and biomarker analyses from CA240-0007.
Jason T. Henry, Deepak Perumal, Jordi Rodon Ahnert, Ben George +16 more
2026Journal of Clinical Oncology0 citations
Semantic Scholar
High dimensional profiling of the immune microenvironment in smoldering multiple myeloma
H. Cho, Nicolas F. Fernandez, Deepak Perumal, A. Rahman +5 more
2019Clinical Lymphoma, Myeloma & Leukemia0 citations
Semantic Scholar
High Dimensional Immune Profiling in Smoldering Multiple Myeloma Identifies Novel Organizing Features of the Tumor Microenvironment
H. Cho, Deepak Perumal, A. Rahman, Seunghee Kim-Schultze +7 more
2019Blood0 citations Open access
Semantic Scholar
MAGE-A3 mediates survival and proliferation through regulation of BIM and p21Cip1 in multiple myeloma
H. Cho, Anna Huo-Chang Mei, Kaity H. Tung, J. Han +6 more
2019Clinical Lymphoma, Myeloma & Leukemia0 citations
Semantic Scholar
Genomic and Immunologic Analysis of Cmaf and Hypermutated Multiple Myeloma: Implications for Immunologic Therapy
H. Cho, Deepak Perumal, A. Rahman, D. Jackson +6 more
2019Blood0 citations Open access
Semantic Scholar
Adar-Mediated Aberrant a-to-I RNA Editing Is Driven By 1q Amplification and Contributes to Proteasome Inhibitor Resistance in Multiple Myeloma
A. Laganà, V. Leshchenko, D. Melnekoff, I. Beno +12 more
20170 citations
Semantic Scholar
MAGE-a Inhibits Apoptosis in Multiple Myeloma through Regulation of Bim and PUMA
H. Cho, A. Mei, J. Fukui, Kaity H. Tung +7 more
20170 citations
Semantic Scholar

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