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S. Chellappan · SciRah

Researcher profile · Semantic Scholar

S. Chellappan

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S. Chellappan — researcher profile on SciRah

h-index: 46
Works: 137
Citations: 6,888

Most-cited papers

Nicotine induces cell proliferation, invasion and epithelial-mesenchymal transition in a variety of human cancer cell lines
P. Dasgupta, Wasia Rizwani, S. Pillai, Rebecca Kinkade +8 more
2009International Journal of Cancer395 citations Open access
Semantic Scholar
Nicotine-mediated cell proliferation and tumor progression in smoking-related cancers
C. Schaal, S. Chellappan
2014Molecular Cancer Research316 citations Open access
Semantic Scholar
EGFR/Src/Akt signaling modulates Sox2 expression and self-renewal of stem-like side-population cells in non-small cell lung cancer
S. Singh, J. Trevino, Namrata Bora-Singhal, D. Coppola +3 more
2012Molecular Cancer250 citations Open access
Semantic Scholar
Nicotine Promotes Tumor Growth and Metastasis in Mouse Models of Lung Cancer
Rebecca K Davis, Wasia Rizwani, Sarmistha Banerjee, Michelle Kovacs +3 more
2009PLoS ONE203 citations Open access
Semantic Scholar
YAP1 REGULATES OCT4 ACTIVITY AND SOX2 EXPRESSION TO FACILITATE SELF-RENEWAL AND VASCULAR MIMICRY OF STEM-LIKE CELLS
Namrata Bora-Singhal, Jonathan Nguyen, C. Schaal, Deepak Perumal +3 more
2015Stem Cells162 citations Open access
Semantic Scholar
Nicotinic Acetylcholine Receptor Signaling in Tumor Growth and Metastasis
S. Singh, S. Pillai, S. Chellappan
2011Journal of Oncology142 citations Open access
Semantic Scholar
Nicotine/Cigarette-smoke Promotes Metastasis of Pancreatic Cancer Through α7nAChR-mediated MUC4 Up-regulation
N. Momi, M. Ponnusamy, S. Kaur, S. Rachagani +4 more
2012Oncogene137 citations Open access
Semantic Scholar
Regulation of Sox2 and stemness by nicotine and electronic-cigarettes in non-small cell lung cancer
C. Schaal, Namrata Bora-Singhal, D. Kumar, S. Chellappan
2018Molecular Cancer129 citations Open access
Semantic Scholar
ARRB1-mediated regulation of E2F target genes in nicotine-induced growth of lung tumors.
P. Dasgupta, Wasia Rizwani, S. Pillai, Rebecca K Davis +6 more
2011Journal of the National Cancer Institute105 citations Open access
Semantic Scholar
Gli1-Mediated Regulation of Sox2 Facilitates Self-Renewal of Stem-Like Cells and Confers Resistance to EGFR Inhibitors in Non–Small Cell Lung Cancer
Namrata Bora-Singhal, Deepak Perumal, Jonathan Nguyen, S. Chellappan
2015Neoplasia101 citations Open access
Semantic Scholar
Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis
S. Pillai, Jonathan Nguyen, Joseph Johnson, E. Haura +2 more
2015Nature Communications97 citations Open access
Semantic Scholar
Regulation of Matrix Metalloproteinase Genes by E2F transcription factors: Rb-Raf-1 interaction as a novel target for metastatic disease
Jackie L. Johnson, S. Pillai, Danielle Pernazza, Said M Sebti +2 more
2011Cancer Research94 citations Open access
Semantic Scholar
HDAC inhibition enhances the in vivo efficacy of MEK inhibitor therapy in uveal melanoma
Fernanda Faião-Flores, Michael F. Emmons, Michael A. Durante, F. Kinose +9 more
2019Clinical Cancer Research88 citations Open access
Semantic Scholar
Novel HDAC11 inhibitors suppress lung adenocarcinoma stem cell self-renewal and overcome drug resistance by suppressing Sox2
Namrata Bora-Singhal, Durairaj Mohankumar, Biswarup Saha, C. Colin +5 more
2020Scientific Reports78 citations Open access
Semantic Scholar
IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer
Jian-ping Guo, Donghwa Kim, J. Gao, C. Kurtyka +8 more
2012Oncogene75 citations Open access
Semantic Scholar
The Rb-E2F transcriptional regulatory pathway in tumor angiogenesis and metastasis.
C. Schaal, S. Pillai, S. Chellappan
2014Advances in Cancer Research74 citations
Semantic Scholar
Nicotine induces inhibitor of differentiation-1 in a Src-dependent pathway promoting metastasis and chemoresistance in pancreatic adenocarcinoma.
J. Trevino, S. Pillai, Sateesh S. Kunigal, S. Singh +3 more
2012Neoplasia74 citations Open access
Semantic Scholar
Fascin Controls Metastatic Colonization and Mitochondrial Oxidative Phosphorylation by Remodeling Mitochondrial Actin Filaments
Shengchen Lin, Chong-Biao Huang, V. Gunda, Jian-Wei Sun +8 more
2019Cell Reports72 citations Open access
Semantic Scholar
β-arrestin-1 mediates nicotine-induced metastasis through E2F1 target genes that modulate epithelial-mesenchymal transition
S. Pillai, J. Trevino, B. Rawal, S. Singh +6 more
2015Cancer Research71 citations Open access
Semantic Scholar
Small molecule regulators of Rb-E2F pathway as modulators of transcription
S. Singh, Jackie L. Johnson, S. Chellappan
2010Biochimica et Biophysica Acta58 citations Open access
Semantic Scholar
Lung Cancer Stem Cells: Molecular features and Therapeutic Targets
S. Singh, S. Chellappan
2013Molecular Aspects of Medicine55 citations Open access
Semantic Scholar
GATA3 Transcription Factor Abrogates Smad4 Transcription Factor-mediated Fascin Overexpression, Invadopodium Formation, and Breast Cancer Cell Invasion*
Jian-Wei Sun, Hui-Fang He, S. Pillai, Y. Xiong +4 more
2013Journal of Biological Chemistry55 citations Open access
Semantic Scholar
Genetic and Biochemical Alterations in Non-Small Cell Lung Cancer
Jackie L. Johnson, S. Pillai, S. Chellappan
2012Biochemistry Research International55 citations Open access
Semantic Scholar
A small molecule disruptor of Rb/Raf-1 interaction inhibits cell proliferation, angiogenesis, and growth of human tumor xenografts in nude mice.
Rebecca Kinkade, P. Dasgupta, Adam Carie, Daniele Pernazza +5 more
2008Cancer Research55 citations Open access
Semantic Scholar
Cationic lipid guided short-hairpin RNA interference of annexin A2 attenuates tumor growth and metastasis in a mouse lung cancer stem cell model
T. Andey, S. Marepally, Apurva Patel, Tanise L. Jackson +6 more
2014Journal of Controlled Release49 citations Open access
Semantic Scholar
The Role of nAChR and Calcium Signaling in Pancreatic Cancer Initiation and Progression
C. Schaal, J. Padmanabhan, S. Chellappan
2015Cancers48 citations Open access
Semantic Scholar
Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and β-catenin signaling
N. Woods, J. Trevino, D. Coppola, S. Chellappan +2 more
2015OncoTarget46 citations Open access
Semantic Scholar
Nicotine-Mediated Regulation of Nicotinic Acetylcholine Receptors in Non-Small Cell Lung Adenocarcinoma by E2F1 and STAT1 Transcription Factors
C. Schaal, S. Chellappan
2016PLoS ONE45 citations Open access
Semantic Scholar
Nicotine-mediated invasion and migration of non-small cell lung carcinoma cells by modulating STMN3 and GSPT1 genes in an ID1-dependent manner
Sajith Nair, Namrata Bora-Singhal, Deepak Perumal, S. Chellappan
2014Molecular Cancer45 citations Open access
Semantic Scholar
α7 nicotinic acetylcholine receptor subunit in angiogenesis and epithelial to mesenchymal transition.
S. Pillai, S. Chellappan
2012Current Drug Targets44 citations
Semantic Scholar
βArrestin-1 and Mcl-1 Modulate Self-Renewal Growth of Cancer Stem-Like Side-Population Cells in Non-Small Cell Lung Cancer
S. Singh, Namrata Bora-Singhal, Jodi L. Kroeger, Hanane Laklai +1 more
2013PLoS ONE43 citations Open access
Semantic Scholar
TNF-α-mediated proliferation of vascular smooth muscle cells involves Raf-1-mediated inactivation of Rb and transcription of E2F1-regulated genes
Rebecca K Davis, S. Pillai, N. Lawrence, S. Chellappan
2012Cell Cycle43 citations Open access
Semantic Scholar
Mammalian Lysine Histone Demethylase KDM2A Regulates E2F1-Mediated Gene Transcription in Breast Cancer Cells
Wasia Rizwani, C. Schaal, Sateesh S. Kunigal, D. Coppola +1 more
2014PLoS ONE41 citations Open access
Semantic Scholar
Nicotinic acetylcholine receptors induce c-Kit ligand/Stem Cell Factor and promote stemness in an ARRB1/ β-arrestin-1 dependent manner in NSCLC
Deepak Perumal, S. Pillai, Jonathan Nguyen, C. Schaal +2 more
2014OncoTarget40 citations Open access
Semantic Scholar
ChIP on chip assays: genome-wide analysis of transcription factor binding and histone modifications.
S. Pillai, S. Chellappan
2009Methods in molecular biology40 citations
Semantic Scholar
Prohibitin physically interacts with MCM proteins and inhibits mammalian DNA replication
Wasia Rizwani, M. Alexandrow, S. Chellappan
2009Cell Cycle40 citations Open access
Semantic Scholar
The Nek2 centrosome-mitotic kinase contributes to the mesenchymal state, cell invasion, and migration of triple-negative breast cancer cells
Yainyrette Rivera-Rivera, M. Marina, Shirley Jusino, Miyoung Lee +6 more
2021Scientific Reports32 citations Open access
Semantic Scholar
Nicotine, IFN-γ and retinoic acid mediated induction of MUC4 in pancreatic cancer requires E2F1 and STAT-1 transcription factors and utilize different signaling cascades
Sateesh S. Kunigal, M. Ponnusamy, N. Momi, S. Batra +1 more
2012Molecular Cancer32 citations Open access
Semantic Scholar
Chromatin immunoprecipitation assays: analyzing transcription factor binding and histone modifications in vivo.
S. Pillai, P. Dasgupta, S. Chellappan
2009Methods in molecular biology30 citations
Semantic Scholar
Nicotine-mediated induction of E-selectin in aortic endothelial cells requires Src kinase and E2F1 transcriptional activity
V. Alamanda, S. Singh, N. Lawrence, S. Chellappan
2012Biochemical and Biophysical Research Communications - BBRC28 citations Open access
Semantic Scholar
A Novel Five Gene Signature Derived from Stem-Like Side Population Cells Predicts Overall and Recurrence-Free Survival in NSCLC
Deepak Perumal, S. Singh, S. Yoder, G. Bloom +1 more
2012PLoS ONE26 citations Open access
Semantic Scholar
CDKN1C Negatively Regulates RNA Polymerase II C-terminal Domain Phosphorylation in an E2F1-dependent Manner*
Yi-Hong Ma, Lu Chen, Gabriela M. Wright, S. Pillai +2 more
2010Journal of Biological Chemistry24 citations Open access
Semantic Scholar
Rb-Raf-1 interaction disruptor RRD-251 induces apoptosis in metastatic melanoma cells and synergizes with dacarbazine
S. Singh, Rebecca K Davis, V. Alamanda, Roberta Pireddu +4 more
2010Molecular Cancer Therapeutics21 citations Open access
Semantic Scholar
Cationic lipoplexes for treatment of cancer stem cell-derived murine lung tumors
T. Andey, Namrata Bora-Singhal, S. Chellappan, Mandip Singh
2019Nanomedicine: Nanotechnology, Biology and Medicine18 citations Open access
Semantic Scholar
CDK7 and CDK9 inhibition interferes with transcription, translation and stemness, and induces cytotoxicity in GBM irrespective of temozolomide sensitivity.
Isha Bhutada, F. Khambati, Shi-Yuan Cheng, D. Tiek +6 more
2023Neuro-Oncology16 citations Open access
Semantic Scholar
Tank Binding Kinase 1 modulates spindle assembly checkpoint components to regulate mitosis in breast and lung cancer cells
M. Maan, N. Agrawal, J. Padmanabhan, C. Leitzinger +3 more
2020Biochimica et biophysica acta. Molecular cell research14 citations Open access
Semantic Scholar
Fendiline Enhances the Cytotoxic Effects of Therapeutic Agents on PDAC Cells by Inhibiting Tumor-Promoting Signaling Events: A Potential Strategy to Combat PDAC
M. Alhothali, Mevin Mathew, Geeta Iyer, H. Lawrence +3 more
2019International Journal of Molecular Sciences13 citations Open access
Semantic Scholar
ChIP on chip and ChIP-Seq assays: genome-wide analysis of transcription factor binding and histone modifications.
S. Pillai, S. Chellappan
2015Methods in molecular biology12 citations
Semantic Scholar
Chromatin immunoprecipitation assays: analyzing transcription factor binding and histone modifications in vivo.
S. Pillai, P. Dasgupta, S. Chellappan
2015Methods in molecular biology11 citations
Semantic Scholar
A Novel PHD2/VHL-mediated Regulation of YAP1 Contributes to VEGF Expression and Angiogenesis
Namrata Bora-Singhal, Biswarup Saha, Durairaj Mohankumar, J. Padmanabhan +2 more
2022Cancer Research Communications10 citations Open access
Semantic Scholar

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D. Coppola×11
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S. Singh×11
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Namrata Bora-Singhal×9
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C. Schaal — researcher profile on SciRah

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