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P. Launay · SciRah

Researcher profile · Semantic Scholar

P. Launay

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P. Launay — researcher profile on SciRah

h-index: 47
Works: 98
Citations: 8,198

Most-cited papers

ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology
A. Perraud, A. Fleig, Christopher A. Dunn, Leigh Ann Bagley +8 more
2001Nature922 citations
Semantic Scholar
TRPM4 Is a Ca2 -Activated Nonselective Cation Channel Mediating Cell Membrane Depolarization
P. Launay, A. Fleig, A. Perraud, A. Scharenberg +2 more
2002734 citations
Semantic Scholar
TRPM4 Regulates Calcium Oscillations After T Cell Activation
P. Launay, Henrique Cheng, S. Srivatsan, R. Penner +2 more
2004Science333 citations
Semantic Scholar
Identification of FcαRI as an Inhibitory Receptor that Controls Inflammation: Dual Role of FcRγ ITAM
Benoit Pasquier, P. Launay, Yutaka Kanamaru, I. Moura +7 more
2005327 citations Open access
Semantic Scholar
Hemogenic Endothelial Fate Mapping Reveals Dual Developmental Origin of Mast Cells
R. Gentek, Clément Ghigo, G. Hoeffel, Maxime Jacques Bulle +6 more
2018Immunity280 citations Open access
Semantic Scholar
Fcα Receptor (Cd89) Mediates the Development of Immunoglobulin a (Iga) Nephropathy (Berger's Disease)
P. Launay, B. Grossetête, Michelle Arcos-Fajardo, Emmanuelle Gaudin +5 more
2000Journal of Experimental Medicine245 citations Open access
Semantic Scholar
Identification of FcalphaRI as an inhibitory receptor that controls inflammation: dual role of FcRgamma ITAM.
Benoit Pasquier, P. Launay, Yutaka Kanamaru, I. Moura +7 more
2005Immunity226 citations
Semantic Scholar
The calcium-activated nonselective cation channel TRPM4 is essential for the migration but not the maturation of dendritic cells
Gaetan Barbet, M. Demion, I. Moura, Nicolas Serafini +6 more
2008Nature Immunology214 citations Open access
Semantic Scholar
A Subset of Human Dendritic Cells Expresses IgA Fc Receptor (CD89), Which Mediates Internalization and Activation Upon Cross-Linking by IgA Complexes
F. Geissmann, P. Launay, Benoit Pasquier, Y. Lepelletier +4 more
2001Journal of Immunology180 citations
Semantic Scholar
Inhibitory ITAMs as novel regulators of immunity
U. Blank, P. Launay, M. Benhamou, R. Monteiro
2009Immunological Reviews175 citations
Semantic Scholar
Adenosine Receptor Antagonists Including Caffeine Alter Fetal Brain Development in Mice
Carla G. Silva, C. Métin, W. Fazeli, Nuno J. Machado +15 more
2013Science Translational Medicine172 citations Open access
Semantic Scholar
TRPM4, a Ca2+-activated nonselective cation channel in mouse sino-atrial node cells.
M. Demion, P. Bois, P. Launay, R. Guinamard
2007Cardiovascular Research172 citations
Semantic Scholar
A Pyrazole Derivative Potently Inhibits Lymphocyte Ca2+ Influx and Cytokine Production by Facilitating Transient Receptor Potential Melastatin 4 Channel Activity
Ryuichi Takezawa, Henrique Cheng, Andreas Beck, J. Ishikawa +6 more
2006Molecular Pharmacology166 citations
Semantic Scholar
TRPM4 controls insulin secretion in pancreatic β-cells
Henrique Cheng, Andreas Beck, P. Launay, S. Gross +4 more
2007160 citations Open access
Semantic Scholar
9‐Phenanthrol inhibits human TRPM4 but not TRPM5 cationic channels
T. Grand, M. Demion, C. Norez, Y. Mettey +4 more
2008British Journal of Pharmacology156 citations Open access
Semantic Scholar
Tangentially migrating neurons assemble a primary cilium that promotes their reorientation to the cortical plate.
J. Baudoin, Lucie Viou, P. Launay, C. Luccardini +10 more
2012Neuron155 citations Open access
Semantic Scholar
β-Catenin Activation Is Associated with Specific Clinical and Pathologic Characteristics and a Poor Outcome in Adrenocortical Carcinoma
S. Gaujoux, S. Grabar, M. Fassnacht, B. Ragazzon +12 more
2010Clinical Cancer Research153 citations Open access
Semantic Scholar
Transcriptome analysis reveals that p53 and {beta}-catenin alterations occur in a group of aggressive adrenocortical cancers.
B. Ragazzon, R. Libé, S. Gaujoux, G. Assié +7 more
2010Cancer Research147 citations Open access
Semantic Scholar
Wnt/beta-catenin and 3',5'-cyclic adenosine 5'-monophosphate/protein kinase A signaling pathways alterations and somatic beta-catenin gene mutations in the progression of adrenocortical tumors.
S. Gaujoux, F. Tissier, L. Groussin, R. Libé +6 more
2008Journal of Clinical Endocrinology and Metabolism143 citations Open access
Semantic Scholar
Mast cells aggravate sepsis by inhibiting peritoneal macrophage phagocytosis.
Albert Dahdah, G. Gautier, T. Attout, F. Fiore +10 more
2014Journal of Clinical Investigation131 citations Open access
Semantic Scholar
Immune sensing of food allergens promotes avoidance behaviour
E. Florsheim, N. Bachtel, Jaime Cullen, Bruna G. C. Lima +10 more
2023Nature130 citations Open access
Semantic Scholar
Wnt/β-catenin pathway activation in adrenocortical adenomas is frequently due to somatic CTNNB1-activating mutations, which are associated with larger and nonsecreting tumors: a study in cortisol-secreting and -nonsecreting tumors.
S. Bonnet, S. Gaujoux, P. Launay, C. Baudry +11 more
2010Journal of Clinical Endocrinology and Metabolism125 citations Open access
Semantic Scholar
Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction
Anta Ngkelo, A. Richart, Jonathan A. Kirk, P. Bonnin +23 more
2016Journal of Experimental Medicine118 citations Open access
Semantic Scholar
SLC41A1 Is a Novel Mammalian Mg2+ Carrier*
M. Kolisek, P. Launay, Andreas Beck, G. Sponder +6 more
2008Journal of Biological Chemistry111 citations Open access
Semantic Scholar
Lyn and Fyn function as molecular switches that control immunoreceptors to direct homeostasis or inflammation
S. B. Mkaddem, Alejandro Murua, H. Flament, Dimitri Titeca-Beauport +8 more
2017Nature Communications110 citations Open access
Semantic Scholar
Mast Cells as Cellular Sensors in Inflammation and Immunity
Walid Beghdadi, L. C. Madjene, M. Benhamou, N. Charles +3 more
2011Front. Immun.103 citations Open access
Semantic Scholar
Ocular inflammation induces trigeminal pain, peripheral and central neuroinflammatory mechanisms.
P. Launay, É. Reboussin, Hong Liang, K. Kessal +6 more
2016Neurobiology of Disease101 citations Open access
Semantic Scholar
Clinical Cancer esearch an Cancer Biology tivation of the APC Gene Is Constant in Adrenocortical ors from Patients with Familial Adenomatous Polyposis R Not Frequent in Sporadic Adrenocortical Cancers
S. Anne, tien Gaujoux, S. Pinson, A. Gimenez-Roqueplo +10 more
201099 citations
Semantic Scholar
Alternative Endocytic Pathway for Immunoglobulin A Fc Receptors (CD89) Depends on the Lack of FcRγ Association and Protects against Degradation of Bound Ligand*
P. Launay, C. Patry, A. Lehuen, Benoit Pasquier +2 more
1999Journal of Biological Chemistry98 citations Open access
Semantic Scholar
IgG1 and IVIg induce inhibitory ITAM signaling through FcγRIII controlling inflammatory responses.
M. Aloulou, S. Ben Mkaddem, M. Biarnes-Pelicot, Tarek Boussetta +8 more
2012Blood97 citations Open access
Semantic Scholar
TREM-1 multimerization is essential for its activation on monocytes and neutrophils
Kévin Carrasco, A. Boufenzer, L. Jolly, Helene Le Cordier +9 more
2018Cellular & Molecular Immunology96 citations Open access
Semantic Scholar
Shifting FcγRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis.
S. Ben Mkaddem, G. Hayem, F. Jönsson, Elisabetta Rossato +8 more
2014Journal of Clinical Investigation96 citations Open access
Semantic Scholar
The TRPM4 Channel Controls Monocyte and Macrophage, but Not Neutrophil, Function for Survival in Sepsis
Nicolas Serafini, Albert Dahdah, Gaetan Barbet, M. Demion +10 more
2012Journal of Immunology90 citations Open access
Semantic Scholar
TRPM4 controls insulin secretion in pancreatic beta-cells.
Henrique Cheng, Andreas Beck, P. Launay, S. Gross +4 more
2007Cell Calcium90 citations
Semantic Scholar
Physiological roles of the TRPM4 channel extracted from background currents.
R. Guinamard, M. Demion, P. Launay
2010Physiology89 citations
Semantic Scholar
Inhibitory ITAM Signaling Traps Activating Receptors with the Phosphatase SHP-1 to Form Polarized “Inhibisome” Clusters
Séverine Pfirsch-Maisonnas, M. Aloulou, Ting Xu, Julien Claver +5 more
2011Science Signaling87 citations
Semantic Scholar
Pathogenic significance of IgA receptor interactions in IgA nephropathy.
R. Monteiro, I. Moura, P. Launay, T. Tsuge +4 more
2002Trends in Molecular Medicine84 citations
Semantic Scholar
The TRPM4 non-selective cation channel contributes to the mammalian atrial action potential.
C. Simard, T. Hof, Zakia Keddache, P. Launay +1 more
2013Journal of Molecular and Cellular Cardiology82 citations
Semantic Scholar
Colostral neutrophils express Fcα receptors (CD89) lacking γ chain association and mediate noninflammatory properties of secretory IgA
Adenilda C. Honorio-França, P. Launay, M. Carneiro-Sampaio, R. Monteiro
2001Journal of Leukocyte Biology79 citations
Semantic Scholar
Trpm4 Gene Invalidation Leads to Cardiac Hypertrophy and Electrophysiological Alterations
M. Demion, J. Thireau, Mélanie Gueffier, Amanda Finan +8 more
2014PLoS ONE74 citations Open access
Semantic Scholar
CD47 Agonist Peptides Induce Programmed Cell Death in Refractory Chronic Lymphocytic Leukemia B Cells via PLCγ1 Activation: Evidence from Mice and Humans
A. Martínez-Torres, C. Quiney, T. Attout, Héloise Boullet +14 more
2015PLoS Medicine73 citations Open access
Semantic Scholar
Substitution p.A350V in Na+/Mg2+ Exchanger SLC41A1, Potentially Associated with Parkinson's Disease, Is a Gain-of-Function Mutation
M. Kolisek, G. Sponder, Lucia Mastrototaro, A. Smorodchenko +3 more
2013PLoS ONE68 citations Open access
Semantic Scholar
IgA Fc receptor (CD89) activation enables coupling to syk and Btk tyrosine kinase pathways: differential signaling after IFN‐γ or phorbol ester stimulation
P. Launay, A. Lehuen, T. Kawakami, U. Blank +1 more
1998Journal of Leukocyte Biology67 citations
Semantic Scholar
The glomerular response to IgA deposition in IgA nephropathy.
I. Moura, M. Benhamou, P. Launay, F. Vrtovsnik +2 more
2008Seminars in Nephrology65 citations
Semantic Scholar
Silencing Mutated β-Catenin Inhibits Cell Proliferation and Stimulates Apoptosis in the Adrenocortical Cancer Cell Line H295R
S. Gaujoux, C. Hantel, P. Launay, S. Bonnet +8 more
2013PLoS ONE54 citations Open access
Semantic Scholar
Fcα receptor I activation induces leukocyte recruitment and promotes aggravation of glomerulonephritis through the FcRγ adaptor
Yutaka Kanamaru, Michelle Arcos-Fajardo, I. Moura, T. Tsuge +10 more
200752 citations
Semantic Scholar
Combined 3DISCO clearing method, retrograde tracer and ultramicroscopy to map corneal neurons in a whole adult mouse trigeminal ganglion.
P. Launay, D. Godefroy, Hanen Khabou, W. Rostène +4 more
2015Experimental Eye Research51 citations Open access
Semantic Scholar
Differential contribution of TRPM4 and TRPM5 nonselective cation channels to the slow afterdepolarization in mouse prefrontal cortex neurons
Ya-Ting Lei, Sébastien J. Thuault, P. Launay, R. Margolskee +2 more
2014Frontiers in Cellular Neuroscience43 citations Open access
Semantic Scholar
Colostral neutrophils express Fc alpha receptors (CD89) lacking gamma chain association and mediate noninflammatory properties of secretory IgA.
A. Honório-França, P. Launay, M. Carneiro-Sampaio, R. Monteiro
2001Journal of Leukocyte Biology42 citations
Semantic Scholar
Mast cells in renal inflammation and fibrosis: lessons learnt from animal studies.
L. C. Madjene, Maguelonne Pons, Luca Danelli, Julien Claver +14 more
2015Molecular Immunology40 citations
Semantic Scholar

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R. Monteiro×19
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R. Monteiro — researcher profile on SciRah
U. Blank×14
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U. Blank — researcher profile on SciRah
M. Benhamou×12
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M. Benhamou — researcher profile on SciRah
J. Kinet×8
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A. Fleig — researcher profile on SciRah

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G. Gautier — researcher profile on SciRah

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R. Penner — researcher profile on SciRah

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I. Moura — researcher profile on SciRah

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M. Demion — researcher profile on SciRah

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A. Lehuen — researcher profile on SciRah