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S. Ben Mkaddem · SciRah

Researcher profile · Semantic Scholar

S. Ben Mkaddem

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S. Ben Mkaddem — researcher profile on SciRah

h-index: 28
Works: 57
Citations: 2,647

Most-cited papers

New insights in the pathogenesis of immunoglobulin A vasculitis (Henoch-Schönlein purpura).
Marieke H. Heineke, A. Ballering, A. Jamin, S. Ben Mkaddem +2 more
2017Autoimmunity Reviews301 citations Open access
Semantic Scholar
Understanding Fc Receptor Involvement in Inflammatory Diseases: From Mechanisms to New Therapeutic Tools
S. Ben Mkaddem, M. Benhamou, R. Monteiro
2019Frontiers in Immunology254 citations Open access
Semantic Scholar
NADPH Oxidase 1 Modulates WNT and NOTCH1 Signaling To Control the Fate of Proliferative Progenitor Cells in the Colon
N. Coant, S. Ben Mkaddem, E. Pédruzzi, Cécile Guichard +17 more
2010Molecular and Cellular Biology179 citations Open access
Semantic Scholar
IgA, IgA receptors, and their anti-inflammatory properties.
S. Ben Mkaddem, Ivy Christou, Elisabetta Rossato, L. Berthelot +2 more
2014Current Topics in Microbiology and Immunology115 citations
Semantic Scholar
Gluten exacerbates IgA nephropathy in humanized mice through gliadin-CD89 interaction.
Christina Papista, S. Lechner, S. Ben Mkaddem, Marie-Bénédicte LeStang +11 more
2015Kidney International102 citations Open access
Semantic Scholar
IgG1 and IVIg induce inhibitory ITAM signaling through FcγRIII controlling inflammatory responses.
M. Aloulou, S. Ben Mkaddem, M. Biarnes-Pelicot, Tarek Boussetta +8 more
2012Blood97 citations Open access
Semantic Scholar
NOX enzymes and Toll-like receptor signaling
É. Ogier-Denis, S. Ben Mkaddem, A. Vandewalle
2008Seminars in Immunopathology97 citations
Semantic Scholar
Shifting FcγRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis.
S. Ben Mkaddem, G. Hayem, F. Jönsson, Elisabetta Rossato +8 more
2014Journal of Clinical Investigation96 citations Open access
Semantic Scholar
Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury
S. Ben Mkaddem, E. Pédruzzi, C. Werts, N. Coant +5 more
2010Cell Death and Differentiation94 citations Open access
Semantic Scholar
Pore-forming epsilon toxin causes membrane permeabilization and rapid ATP depletion-mediated cell death in renal collecting duct cells.
C. Chassin, M. Bens, J. de Barry, R. Courjaret +7 more
2007AJP - Renal Physiology93 citations
Semantic Scholar
Modulation of the microbiota by oral antibiotics treats immunoglobulin A nephropathy in humanized mice.
J. Chemouny, P. Gleeson, L. Abbad, Gabriella Lauriero +14 more
2018Nephrology, Dialysis and Transplantation90 citations
Semantic Scholar
Reduced expression of the NADPH oxidase NOX4 is a hallmark of adipocyte differentiation.
S. Mouche, S. Ben Mkaddem, Wei Wang, M. Katić +9 more
2007Biochimica et Biophysica Acta87 citations Open access
Semantic Scholar
High levels of gut-homing immunoglobulin A+ B lymphocytes support the pathogenic role of intestinal mucosal hyperresponsiveness in immunoglobulin A nephropathy patients
F. Sallustio, C. Curci, N. Chaoul, G. Fontò +11 more
2020Nephrology, Dialysis and Transplantation84 citations Open access
Semantic Scholar
Anti-inflammatory role of the IgA Fc receptor (CD89): from autoimmunity to therapeutic perspectives.
S. Ben Mkaddem, Elisabetta Rossato, N. Heming, R. Monteiro
2013Autoimmunity Reviews82 citations
Semantic Scholar
Les Nox/Duox : une nouvelle famille de NADPH oxydases
Cécile Guichard, E. Pedruzzi, M. Fay, S. Ben Mkaddem +3 more
200673 citations Open access
Semantic Scholar
Clostridium septicum alpha-toxin forms pores and induces rapid cell necrosis.
O. Knapp, E. Maier, S. Ben Mkaddem, R. Benz +5 more
2010Toxicon70 citations
Semantic Scholar
Potentiation of Epithelial Innate Host Responses by Intercellular Communication
Tamas Dolowschiak, C. Chassin, S. Ben Mkaddem, T. Fuchs +3 more
2010PLoS Pathogens66 citations Open access
Semantic Scholar
LC3-associated phagocytosis protects against inflammation and liver fibrosis via immunoreceptor inhibitory signaling
J. Wan, E. Weiss, S. Ben Mkaddem, M. Mabire +13 more
2020Science Translational Medicine63 citations
Semantic Scholar
CD31 is a key coinhibitory receptor in the development of immunogenic dendritic cells
M. Clément, G. Fornasa, K. Guedj, S. Ben Mkaddem +5 more
2014Proceedings of the National Academy of Sciences of the United States of America60 citations Open access
Semantic Scholar
Differential activation of Toll-like receptor-mediated apoptosis induced by hypoxia
S. Ben Mkaddem, M. Bens, A. Vandewalle
2010OncoTarget54 citations Open access
Semantic Scholar
Reversal of Arthritis by Human Monomeric IgA Through the Receptor‐Mediated SH2 Domain–Containing Phosphatase 1 Inhibitory Pathway
Elisabetta Rossato, S. Ben Mkaddem, Yutaka Kanamaru, M. Hurtado-Nedelec +6 more
2015Arthritis & Rheumatology53 citations
Semantic Scholar
Heat Shock Protein gp96 Interacts with Protein Phosphatase 5 and Controls Toll-like Receptor 2 (TLR2)-mediated Activation of Extracellular Signal-regulated Kinase (ERK) 1/2 in Post-hypoxic Kidney Cells*
S. Ben Mkaddem, C. Werts, J. Goujon, M. Bens +3 more
2009Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Cyclosporine A Impairs Nucleotide Binding Oligomerization Domain (Nod1)-Mediated Innate Antibacterial Renal Defenses in Mice and Human Transplant Recipients
E. Tourneur, S. Ben Mkaddem, C. Chassin, M. Bens +12 more
2013PLoS Pathogens46 citations Open access
Semantic Scholar
Cannabinoids as Immune System Modulators: Cannabidiol Potential Therapeutic Approaches and Limitations
Abdel Aziz, L. C. Nguyen, Loubna Oumeslakht, A. Bensussan +1 more
2022Cannabis and Cannabinoid Research36 citations
Semantic Scholar
Rifaximin as a Potential Treatment for IgA Nephropathy in a Humanized Mice Model
V. Di Leo, P. Gleeson, F. Sallustio, Carine Bounaix +4 more
2021Journal of Personalized Medicine34 citations Open access
Semantic Scholar
Serum Iron Protects from Renal Postischemic Injury.
Céline Vaugier, M. Amano, J. Chemouny, Michael Dussiot +21 more
2017Journal of the American Society of Nephrology33 citations Open access
Semantic Scholar
Early Phase Mast Cell Activation Determines the Chronic Outcome of Renal Ischemia–Reperfusion Injury
Luca Danelli, L. C. Madjene, I. Madera-Salcedo, G. Gautier +6 more
2017Journal of Immunology30 citations Open access
Semantic Scholar
Flagellin/TLR5 signalling activates renal collecting duct cells and facilitates invasion and cellular translocation of uropathogenic Escherichia coli
M. Bens, S. Vimont, S. Ben Mkaddem, C. Chassin +5 more
2014Cellular Microbiology29 citations
Semantic Scholar
[The Nox/Duox family of ROS-generating NADPH oxidases].
Cécile Guichard, E. Pédruzzi, M. Fay, S. Ben Mkaddem +3 more
2006Medecine sciences : M/S28 citations
Semantic Scholar
CD89 Is a Potent Innate Receptor for Bacteria and Mediates Host Protection from Sepsis.
C. de Tymowski, N. Heming, M. D. T. Correia, L. Abbad +15 more
2019Cell Reports21 citations Open access
Semantic Scholar
LC3-associated phagocytosis in myeloid cells, a fireman that restrains inflammation and liver fibrosis, via immunoreceptor inhibitory signalling.
J. Wan, E. Weiss, S. Ben Mkaddem, M. Mabire +11 more
2020Autophagy20 citations Open access
Semantic Scholar
Role of FcγRIIIA (CD16) in IVIg-Mediated Anti-Inflammatory Function
S. Ben Mkaddem, M. Aloulou, M. Benhamou, R. Monteiro
2014Journal of Clinical Immunology20 citations
Semantic Scholar
Protective role of mouse IgG1 in cryoglobulinaemia; insights from an animal model and relevance to human pathology.
J. Chemouny, M. Hurtado-Nedelec, H. Flament, S. Ben Mkaddem +4 more
2016Nephrology, Dialysis and Transplantation14 citations Open access
Semantic Scholar
Glioblastoma-associated macrophages: A key target in overcoming glioblastoma therapeutic resistance.
Aymane Kricha, Najat Bouchmaa, S. Ben Mkaddem, Abdellatif Abbaoui +2 more
2024Cytokine & growth factor reviews13 citations
Semantic Scholar
CD160 receptor in CLL: Current state and future avenues
Loubna Oumeslakht, Abdel Aziz, A. Bensussan, S. Ben Mkaddem
2022Frontiers in Immunology13 citations Open access
Semantic Scholar
Mechanisms Underlying Potential Therapeutic Approaches for COVID-19
A. Benani, S. Ben Mkaddem
2020Frontiers in Immunology11 citations Open access
Semantic Scholar
Contribution of renal tubule epithelial cells in the innate immune response during renal bacterial infections and ischemia-reperfusion injury.
S. Ben Mkaddem, C. Chassin, A. Vandewalle
2010Chang Gung medical journal10 citations
Semantic Scholar
In Situ Synthesis of Polysaccharide-Stabilized Amorphous Calcium Phosphate: Mechanical Performance and In Vitro Biological Assessment
Hamza Elbaza, H. Mabroum, Y. Hamdan, R. El Fatimy +4 more
2025Composites Communications9 citations
Semantic Scholar
Fc receptors act as innate immune receptors during infection?
Chaimaa Laassili, Fatiha Ben El Hend, Riad Benzidane, Loubna Oumeslakht +4 more
2023Frontiers in Immunology8 citations Open access
Semantic Scholar
Negative regulation of bacterial killing and inflammation by two novel CD16 ligands
Jaqueline Beppler, S. Ben Mkaddem, Jussara S Michaloski, R. Honorato +5 more
2016European Journal of Immunology8 citations Open access
Semantic Scholar
Synergistic effects of bioactive glass and sodium alginate on the surface properties and therapeutic release of ciprofloxacin from apatite cements
H. Mabroum, Hamid Ait Said, Hamza Elbaza, Y. Hamdan +8 more
2025International Journal of Pharmaceutics: X3 citations Open access
Semantic Scholar
Bacterial Proliferation May Be the Key Component of Sepsis Mortality
C. de Tymowski, M. D. T. Correia, R. Monteiro, P. Montravers +1 more
2018Infection and Immunity3 citations Open access
Semantic Scholar
Insulin-regulated aminopeptidase contributes to setting the intensity of FcR-mediated inflammation
Manuela Bratti, S. Vibhushan, C. Longé, Despoina Koumantou +6 more
2022Frontiers in Immunology2 citations Open access
Semantic Scholar
Development and validation of the first HBV qRT-PCR assay in the Mediterranean area targeting the X region.
Salma Madihi, Chaimaa Laassili, Samia Boukaira, W. Baha +4 more
2024Journal of Virological Methods1 citations
Semantic Scholar
Tu1738 NOD2 Controls the Paracellular Permeability Related to Macropinocytosis of Enterocyte Tight Junctions in Response to Autophagy
E. Thachil, J. Bucher, S. Ben Mkaddem, D. Château +8 more
20131 citations
Semantic Scholar
IL4I1+ Macrophage Accumulation in Advanced Cutaneous T-Cell Lymphomas Suggests a Role in Tumor Immune Escape.
Oumeslakht Loubna, B. Papouin, C. Lamaison, S. Ingen-Housz-Oro +5 more
2026Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
Abstract 4800: Targeting CD160 as an immunotherapy approach to modulate tumor angiogenesis and improve outcomes in triple-negative breast cancer
Abdel Aziz, Maxence Mocquery-corre, Chloé Jean, Jessica Thevenard-Devy +9 more
2026Cancer Research0 citations
Semantic Scholar
1193 Identification of ICOS/ICOSL co-expression in Sézary syndrome and their therapeutic targeting
Loubna Oumeslakht, Jérôme Giustiniani, A. Decroos, R. El Fatimy +4 more
2025Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
High levels of gut-homing immunoglobulin A + B lymphocytes support the pathogenic role of intestinal mucosal hyperresponsiveness in immunoglobulin A nephropathy patients
F. Sallustio, C. Curci, Nada Chaoul, Giulia Fontò +11 more
20210 citations
Semantic Scholar
Shifting Fc (cid:13) RIIA-ITAM from activation to inhibitory configuration ameliorates arthritis.
S. Ben Mkaddem, G. Hayem, F. Jönsson, Elisabetta Rossato +8 more
20200 citations
Semantic Scholar

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