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A. Lehuen · SciRah

Researcher profile · Semantic Scholar

A. Lehuen

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A. Lehuen — researcher profile on SciRah

h-index: 49
Works: 144
Citations: 8,611

Most-cited papers

Immune cell crosstalk in type 1 diabetes
A. Lehuen, J. Diana, P. Zaccone, A. Cooke
2010Nature reviews. Immunology491 citations
Semantic Scholar
Crosstalk between neutrophils, B-1a cells and plasmacytoid dendritic cells initiates autoimmune diabetes
J. Diana, Y. Simoni, L. Furio, L. Beaudoin +3 more
2012Nature Medicine421 citations
Semantic Scholar
Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition)
A. Cossarizza, Hyun-Dong Chang, A. Radbruch, A. Acs +432 more
2019European Journal of Immunology306 citations Open access
Semantic Scholar
Mucosal-associated invariant T cell alterations in obese and type 2 diabetic patients.
Isabelle Magalhaes, Karine Pingris, C. Poitou, Stéphanie Bessoles +18 more
2015Journal of Clinical Investigation281 citations Open access
Semantic Scholar
Mucosal-associated invariant T cells and disease
A. Toubal, Isabelle Nel, S. Lotersztajn, A. Lehuen
2019Nature reviews. Immunology274 citations
Semantic Scholar
Dual role of Mucosal-Associated Invariant T cells in type 1 diabetes
Ophélie Rouxel, Jennifer da Silva, L. Beaudoin, Isabelle Nel +15 more
2017Nature Immunology225 citations Open access
Semantic Scholar
Mucosal-associated invariant T cells are a profibrogenic immune cell population in the liver
P. Hegde, E. Weiss, V. Paradis, J. Wan +15 more
2018Nature Communications210 citations Open access
Semantic Scholar
Expansion and long-range differentiation of the NKT cell lineage in mice expressing CD1d exclusively on cortical thymocytes
D. Wei, Hyunji Lee, Se-Ho Park, L. Beaudoin +3 more
2005Journal of Experimental Medicine194 citations Open access
Semantic Scholar
Outcome of SARS-CoV-2 infection is linked to MAIT cell activation and cytotoxicity
H. Flament, Matthieu Rouland, L. Beaudoin, A. Toubal +31 more
2021Nature Immunology185 citations Open access
Semantic Scholar
Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity
A. Toubal, Badr Kiaf, L. Beaudoin, Lucie Cagninacci +11 more
2020Nature Communications146 citations Open access
Semantic Scholar
MAIT cells, guardians of skin and mucosa?
Isabelle Nel, L. Bertrand, A. Toubal, A. Lehuen
2021Mucosal Immunology125 citations Open access
Semantic Scholar
NKT cell-plasmacytoid dendritic cell cooperation via OX40 controls viral infection in a tissue-specific manner.
J. Diana, T. Griseri, S. Lagaye, L. Beaudoin +8 more
2009Immunity118 citations Open access
Semantic Scholar
IgA, IgA receptors, and their anti-inflammatory properties.
S. Ben Mkaddem, Ivy Christou, Elisabetta Rossato, L. Berthelot +2 more
2014Current Topics in Microbiology and Immunology115 citations
Semantic Scholar
Viral infection prevents diabetes by inducing regulatory T cells through NKT cell–plasmacytoid dendritic cell interplay
J. Diana, V. Brezar, L. Beaudoin, M. Dalod +6 more
2011Journal of Experimental Medicine101 citations Open access
Semantic Scholar
Mechanism of regulation of autoimmunity by iNKT cells.
J. Novak, A. Lehuen
2011Cytokine92 citations
Semantic Scholar
Therapeutic manipulation of natural killer (NK) T cells in autoimmunity: are we close to reality?
Y. Simoni, J. Diana, L. Ghazarian, L. Beaudoin +1 more
2013Clinical and Experimental Immunology89 citations Open access
Semantic Scholar
Macrophages and β-cells are responsible for CXCR2-mediated neutrophil infiltration of the pancreas during autoimmune diabetes
J. Diana, A. Lehuen
2014EMBO Molecular Medicine88 citations Open access
Semantic Scholar
NKT cells: Friend or foe during viral infections?
J. Diana, A. Lehuen
2009European Journal of Immunology84 citations Open access
Semantic Scholar
Secretory IgA Induces Tolerogenic Dendritic Cells through SIGNR1 Dampening Autoimmunity in Mice
J. Diana, I. Moura, Céline Vaugier, A. Gestin +6 more
2013Journal of Immunology81 citations Open access
Semantic Scholar
Intestinal invalidation of the glucose transporter GLUT2 delays tissue distribution of glucose and reveals an unexpected role in gut homeostasis
C. Schmitt, Thomas Aranias, T. Viel, D. Château +12 more
2016Molecular Metabolism78 citations Open access
Semantic Scholar
TRAIL but not FasL and TNFα, regulates IL‐33 expression in murine hepatocytes during acute hepatitis
M. Arshad, C. Piquet-Pellorce, A. L'helgoualc'h, M. Rauch +9 more
2012Hepatology68 citations Open access
Semantic Scholar
Invariant NKT Cells Regulate Experimental Autoimmune Encephalomyelitis and Infiltrate the Central Nervous System in a CD1d-Independent Manner1
L. Mars, Anne‐Sophie Gautron, J. Novak, L. Beaudoin +3 more
2008Journal of Immunology67 citations
Semantic Scholar
Invariant Vα14+ NKT Cells Participate in the Early Response to Enteric Listeria monocytogenes Infection1
Thomas Ranson, S. Bregenholt, A. Lehuen, O. Gaillot +4 more
2005Journal of Immunology66 citations
Semantic Scholar
Regulation of Type 1 Diabetes by NKT Cells
J. Novak, T. Griseri, L. Beaudoin, A. Lehuen
2007International Reviews of Immunology65 citations
Semantic Scholar
A Griscelli syndrome type 2 murine model of hemophagocytic lymphohistiocytosis (HLH)
Jana Pachlopnik Schmid, Chen-Hsuan Ho, J. Diana, G. Pivert +4 more
2008European Journal of Immunology61 citations Open access
Semantic Scholar
IRF5 governs liver macrophage activation that promotes hepatic fibrosis in mice and humans.
F. Alzaid, Floriane Lagadec, M. Albuquerque, R. Ballaire +10 more
2016JCI Insight60 citations Open access
Semantic Scholar
iNKT and MAIT Cell Alterations in Diabetes
Isabelle Magalhaes, Badr Kiaf, A. Lehuen
2015Frontiers in Immunology54 citations Open access
Semantic Scholar
Regulatory role of natural killer T cells in diabetes
Céline Tard, Ophélie Rouxel, A. Lehuen
2015Biomedical Journal54 citations Open access
Semantic Scholar
CD4+ Type II NKT Cells Mediate ICOS and Programmed Death-1–Dependent Regulation of Type 1 Diabetes
N. Kadri, É. Korpos, Shashank Gupta, C. Briet +7 more
2012Journal of Immunology53 citations
Semantic Scholar
Fcα receptor I activation induces leukocyte recruitment and promotes aggravation of glomerulonephritis through the FcRγ adaptor
Yutaka Kanamaru, Michelle Arcos-Fajardo, I. Moura, T. Tsuge +10 more
200752 citations
Semantic Scholar
Mucosal‐associated invariant T cells in autoimmune and immune‐mediated diseases
Ophélie Rouxel, A. Lehuen
2018Immunology and Cell Biology51 citations
Semantic Scholar
NOD mice contain an elevated frequency of iNKT17 cells that exacerbate diabetes
Y. Simoni, Anne‐Sophie Gautron, L. Beaudoin, L. Bui +5 more
2011European Journal of Immunology46 citations Open access
Semantic Scholar
Mucosal‐associated invariant T (MAIT) cells are depleted and prone to apoptosis in cardiometabolic disorders
Sothea Touch, K. Assmann, J. Aron-Wisnewsky, Florian Marquet +10 more
2018The FASEB Journal45 citations
Semantic Scholar
Mast cell chymase protects against renal fibrosis in murine unilateral ureteral obstruction.
Walid Beghdadi, L. C. Madjene, Julien Claver, G. Pejler +4 more
2013Kidney International44 citations Open access
Semantic Scholar
Prevention or acceleration of type 1 diabetes by viruses
L. Ghazarian, J. Diana, Y. Simoni, L. Beaudoin +1 more
2012Cellular and Molecular Life Sciences42 citations Open access
Semantic Scholar
Globosides but not isoglobosides can impact the development of invariant natural killer T cells and their interaction with dendritic cells
S. Porubský, A. Speak, M. Salio, R. Jennemann +11 more
2012Journal of Immunology39 citations Open access
Semantic Scholar
Prevention of Type 1 Diabetes by Invariant NKT Cells Is Independent of Peripheral CD1d Expression1
J. Novak, L. Beaudoin, Seho Park, T. Griseri +3 more
2007Journal of Immunology39 citations Open access
Semantic Scholar
Gut mucosa alterations and loss of segmented filamentous bacteria in type 1 diabetes are associated with inflammation rather than hyperglycaemia
Matthieu Rouland, L. Beaudoin, Ophélie Rouxel, L. Bertrand +14 more
2021Gut36 citations Open access
Semantic Scholar
Plasmacytoid dendritic cells license regulatory T cells, upon iNKT‐cell stimulation, to prevent autoimmune diabetes
L. Beaudoin, J. Diana, L. Ghazarian, Y. Simoni +2 more
2014European Journal of Immunology36 citations Open access
Semantic Scholar
Insulin resistance per se drives early and reversible dysbiosis-mediated gut barrier impairment and bactericidal dysfunction
D. Gueddouri, M. Caüzac, V. Fauveau, F. Benhamed +9 more
2022Molecular Metabolism33 citations Open access
Semantic Scholar
MAIT cells in metabolic diseases
L. Bertrand, A. Lehuen
2019Molecular Metabolism32 citations Open access
Semantic Scholar
A natural protective function of invariant NKT cells in a mouse model of innate‐cell‐driven lung inflammation
E. Bourgeois, A. Levescot, Séverine Diem, A. Chauvineau +9 more
2011European Journal of Immunology32 citations Open access
Semantic Scholar
MAIT cell alterations in adults with recent-onset and long-term type 1 diabetes
Isabelle Nel, L. Beaudoin, Zouriatou Gouda, Camille Rousseau +6 more
2021Diabetologia25 citations Open access
Semantic Scholar
Ablation of interaction between IL-33 and ST2+ regulatory T cells increases immune cell-mediated hepatitis and activated NK cell liver infiltration.
G. Noel, M. Arshad, A. Filliol, V. Genêt +6 more
2016American Journal of Physiology - Gastrointestinal and Liver Physiology23 citations Open access
Semantic Scholar
SLAM‐associated protein favors the development of iNKT2 over iNKT17 cells
Marie‐Laure Michel, C. Lenoir, B. Massot, Séverine Diem +8 more
2016European Journal of Immunology21 citations Open access
Semantic Scholar
Fc alpha receptor I activation induces leukocyte recruitment and promotes aggravation of glomerulonephritis through the FcR gamma adaptor.
Yutaka Kanamaru, Michelle Arcos-Fajardo, I. Moura, T. Tsuge +10 more
2007European Journal of Immunology19 citations
Semantic Scholar
[Mucosal-associated invariant T cells].
Ophélie Rouxel, A. Lehuen
2018Medecine sciences : M/S16 citations Open access
Semantic Scholar
Lights on MAIT cells, a new immune player in liver diseases.
A. Toubal, A. Lehuen
2016Journal of Hepatology16 citations
Semantic Scholar
Low numbers and altered phenotype of invariant natural killer T cells in recurrent varicella zoster virus infection.
L. Nováková, A. Lehuen, J. Novak
2011Cellular Immunology15 citations
Semantic Scholar
Protection Against Type 1 Diabetes Upon Coxsackievirus B4 Infection and iNKT-Cell Stimulation
L. Ghazarian, J. Diana, L. Beaudoin, P. Larsson +4 more
2013Diabetes14 citations Open access
Semantic Scholar

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