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D. Xia · SciRah

Researcher profile · Semantic Scholar

D. Xia

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D. Xia — researcher profile on SciRah

h-index: 39
Works: 109
Citations: 4,570

Most-cited papers

Crystallographic studies of quinol oxidation site inhibitors: a modified classification of inhibitors for the cytochrome bc(1) complex.
L. Esser, B. Quinn, Yong-Fu Li, Min-Quan Zhang +4 more
2004Journal of Molecular Biology263 citations
Semantic Scholar
Structural basis for the quinone reduction in the bc1 complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc1 with bound substrate and inhibitors at the Qi site.
Xiu-Gong Gao, X. Wen, L. Esser, B. Quinn +3 more
2003Biochemistry244 citations
Semantic Scholar
Structural Analysis of Cytochrome bc1 Complexes: Implications to the Mechanism of Function
D. Xia, L. Esser, Wai-Kwan Tang, F. Zhou +3 more
2012Biochimica et Biophysica Acta173 citations Open access
Semantic Scholar
A Mighty “Protein Extractor” of the Cell: Structure and Function of the p97/CDC48 ATPase
Yi-Hong Ye, Wai-Kwan Tang, Ting Zhang, D. Xia
2017Frontiers in Molecular Biosciences171 citations Open access
Semantic Scholar
STRUCTURE AND FUNCTION OF THE AAA+ ATPASE p97/Cdc48p
D. Xia, Wai-Kwan Tang, Yi-Hong Ye
2016Gene169 citations Open access
Semantic Scholar
The A‐loop, a novel conserved aromatic acid subdomain upstream of the Walker A motif in ABC transporters, is critical for ATP binding
S. Ambudkar, In‐Wha Kim, D. Xia, Z. Sauna
2006FEBS Letters168 citations Open access
Semantic Scholar
The role of YAP/TAZ activity in cancer metabolic reprogramming
Xiao-Dong Zhang, Haiying Zhao, Yan Li, D. Xia +3 more
2018Molecular Cancer165 citations Open access
Semantic Scholar
Structures of the Multidrug Transporter P-glycoprotein Reveal Asymmetric ATP Binding and the Mechanism of Polyspecificity*♦
L. Esser, F. Zhou, Kristen M. Pluchino, J. Shiloach +11 more
2016Journal of Biological Chemistry153 citations Open access
Semantic Scholar
A novel ATP‐dependent conformation in p97 N–D1 fragment revealed by crystal structures of disease‐related mutants
Wai-Kwan Tang, Dongyang Li, Chou-Chi H. Li, L. Esser +3 more
2010EMBO Journal146 citations Open access
Semantic Scholar
Structure of a multidrug transporter
M. Gottesman, S. Ambudkar, D. Xia
2009Nature Biotechnology144 citations Open access
Semantic Scholar
Inhibitor-complexed Structures of the Cytochrome bc1 from the Photosynthetic Bacterium Rhodobacter sphaeroides*
L. Esser, M. Elberry, F. Zhou, Chang-An Yu +2 more
2008Journal of Biological Chemistry133 citations Open access
Semantic Scholar
The crystal structure of mitochondrial cytochrome bc1 in complex with famoxadone: the role of aromatic-aromatic interaction in inhibition.
Xiu-Gong Gao, X. Wen, Chang-Hong Yu, L. Esser +5 more
2002Biochemistry127 citations
Semantic Scholar
Surface-modulated motion switch: Capture and release of iron–sulfur protein in the cytochrome bc1 complex
L. Esser, X. Gong, Shao-Qing Yang, Linda P. C. Yu +2 more
2006Proceedings of the National Academy of Sciences of the United States of America113 citations
Semantic Scholar
Crystal Structure of the Heterodimeric Complex of the Adaptor, ClpS, with the N-domain of the AAA+ Chaperone, ClpA*
F. Guo, L. Esser, S. Singh, M. Maurizi +1 more
2002Journal of Biological Chemistry108 citations Open access
Semantic Scholar
Mutations in the Human AAA+ Chaperone p97 and Related Diseases
Wai-Kwan Tang, D. Xia
2016Frontiers in Molecular Biosciences99 citations Open access
Semantic Scholar
Structure of CFA/I fimbriae from enterotoxigenic Escherichia coli
Yong-Fu Li, S. Poole, K. Nishio, K. Jang +5 more
2009Proceedings of the National Academy of Sciences of the United States of America98 citations Open access
Semantic Scholar
Altered Intersubunit Communication Is the Molecular Basis for Functional Defects of Pathogenic p97 Mutants*
Wai-Kwan Tang, D. Xia
2013Journal of Biological Chemistry83 citations Open access
Semantic Scholar
Cryo-EM Analysis of the Conformational Landscape of Human P-glycoprotein (ABCB1) During its Catalytic Cycle
G. A. Frank, S. Shukla, P. Rao, M. Borgnia +9 more
2016Molecular Pharmacology79 citations Open access
Semantic Scholar
Protein binding and disruption by Clp/Hsp100 chaperones.
M. Maurizi, D. Xia
2004Structure69 citations Open access
Semantic Scholar
Structural Basis and Mode of Action for Two Broadly Neutralizing Antibodies Against SARS-CoV-2 Emerging Variants of Concern
Wen-Wei Li, Yao-Zong Chen, Jérémie Prévost, Irfan Ullah +26 more
2021bioRxiv64 citations Open access
Semantic Scholar
Structural Basis of p97 Inhibition by the Site-Selective Anticancer Compound CB-5083
Wai-Kwan Tang, Taivan Odzorig, Whitney Jin, D. Xia
2018Molecular Pharmacology64 citations Open access
Semantic Scholar
Mutations Define Cross-talk between the N-terminal Nucleotide-binding Domain and Transmembrane Helix-2 of the Yeast Multidrug Transporter Pdr5
Z. Sauna, S. Bohn, Robert M. Rutledge, M. Dougherty +5 more
2008Journal of Biological Chemistry62 citations Open access
Semantic Scholar
Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1
X. Jian, Wai-Kwan Tang, P. Zhai, N. Roy +8 more
2015Structure61 citations Open access
Semantic Scholar
Defeating drug resistance in cancer.
M. Gottesman, J. Ludwig, D. Xia, G. Szakács
2006Discover medicine61 citations
Semantic Scholar
A Receptor-binding Site as Revealed by the Crystal Structure of CfaE, the Colonization Factor Antigen I Fimbrial Adhesin of Enterotoxigenic Escherichia coli*
Yong-Fu Li, S. Poole, F. Rasulova, A. Mcveigh +2 more
2007Journal of Biological Chemistry59 citations Open access
Semantic Scholar
Evidence for Electron Equilibrium between the Two Hemes bL in the Dimeric Cytochrome bc1 Complex*
X. Gong, Linda P. C. Yu, D. Xia, Chang-An Yu
2005Journal of Biological Chemistry59 citations Open access
Semantic Scholar
Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone.
D. Xia, L. Esser, S. Singh, F. Guo +1 more
2004Journal of Structural Biology59 citations
Semantic Scholar
The conserved tyrosine residues 401 and 1044 in ATP sites of human P-glycoprotein are critical for ATP binding and hydrolysis: evidence for a conserved subdomain, the A-loop in the ATP-binding cassette.
In‐Wha Kim, Xiang-Hong Peng, Z. Sauna, P. FitzGerald +4 more
2006Biochemistry58 citations
Semantic Scholar
Structural basis for the mechanism of electron bifurcation at the quinol oxidation site of the cytochrome bc1 complex
D. Xia, L. Esser, Linda P. C. Yu, Chang-An Yu
2007Photosynthesis Research53 citations
Semantic Scholar
Elevated Expression of TMEM205, a Hypothetical Membrane Protein, is Associated with Cisplatin Resistance
Ding-Wu Shen, Ji-Chun Ma, Mitsunori Okabe, Guo-Feng Zhang +2 more
2010Journal of Cellular Physiology50 citations Open access
Semantic Scholar
The Signaling Interface of the Yeast Multidrug Transporter Pdr5 Adopts a Cis Conformation and There Is Functional Overlap and Equivalence of the Deviant and Canonical Q-loop Residues
N. Ananthaswamy, Robert M. Rutledge, Z. Sauna, S. Ambudkar +4 more
2010Biochemistry49 citations Open access
Semantic Scholar
Role of the D1-D2 Linker of Human VCP/p97 in the Asymmetry and ATPase Activity of the D1-domain
Wai-Kwan Tang, D. Xia
2016Scientific Reports48 citations Open access
Semantic Scholar
Toward Understanding the Mechanism of Action of the Yeast Multidrug Resistance Transporter Pdr5p: A Molecular Modeling Study
Robert M. Rutledge, L. Esser, Ji-Chun Ma, D. Xia
2010Journal of Structural Biology48 citations Open access
Semantic Scholar
Structures of AAA protein translocase Bcs1 suggest translocation mechanism of a folded protein
Wai-Kwan Tang, M. Borgnia, Allen L. Hsu, L. Esser +3 more
2020Nature Structural & Molecular Biology45 citations Open access
Semantic Scholar
Recognition of Mesothelin by the Therapeutic Antibody MORAb-009
Ji-Chun Ma, Wai-Kwan Tang, L. Esser, I. Pastan +1 more
2012Journal of Biological Chemistry42 citations Open access
Semantic Scholar
Structural basis for the specific recognition of dual receptors by the homopolymeric pH 6 antigen (Psa) fimbriae of Yersinia pestis
R. Bao, M. Nair, Wai-Kwan Tang, L. Esser +4 more
2012Proceedings of the National Academy of Sciences of the United States of America40 citations Open access
Semantic Scholar
Towards understanding the mechanism of action of the multidrug resistance-linked half-ABC transporter ABCG2: a molecular modeling study.
Yong-Fu Li, O. Polgar, Masaki Okada, L. Esser +2 more
2007Journal of Molecular Graphics and Modelling40 citations
Semantic Scholar
Mutational Analysis of Threonine 402 Adjacent to the GXXXG Dimerization Motif in TM1 of ABCG2
O. Polgar, C. Ieranò, A. Tamaki, Bradford J. Stanley +5 more
2010Biochemistry38 citations Open access
Semantic Scholar
Studies on Inhibition of Respiratory Cytochrome bc 1 Complex by the Fungicide Pyrimorph Suggest a Novel Inhibitory Mechanism
Yu-Mei Xiao, L. Esser, F. Zhou, Chang Li +4 more
2014PLoS ONE35 citations Open access
Semantic Scholar
Structures of synthetic nanobody–SARS-CoV-2 receptor-binding domain complexes reveal distinct sites of interaction
J. Ahmad, Jian-Sheng Jiang, L. Boyd, A. Zeher +4 more
2021Journal of Biological Chemistry29 citations Open access
Semantic Scholar
Structural Basis of Resistance to Anti-Cytochrome bc1 Complex Inhibitors: Implication for Drug Improvement
L. Esser, Chang-An Yu, D. Xia
2014Current pharmaceutical design27 citations Open access
Semantic Scholar
Arginine 383 is a crucial residue in ABCG2 biogenesis
O. Polgar, L. Ediriwickrema, R. Robey, Ajay Sharma +8 more
2009Biochimica et Biophysica Acta27 citations Open access
Semantic Scholar
The use of blue native PAGE in the evaluation of membrane protein aggregation states for crystallization.
Ji-Chun Ma, D. Xia
2008Journal of Applied Crystallography27 citations Open access
Semantic Scholar
The Iron-Sulfur Cluster of the Rieske Iron-Sulfur Protein Functions as a Proton-exiting Gate in the Cytochrome bc1 Complex*
Buddha Gurung, Linda P. C. Yu, D. Xia, Chang-An Yu
2005Journal of Biological Chemistry26 citations Open access
Semantic Scholar
Domain conformational switch of the iron-sulfur protein in cytochrome bc1 complex is induced by the electron transfer from cytochrome bL to bH.
Chang-An Yu, Xiaowei Cen, He-Wen Ma, Ying Yin +3 more
2008Biochimica et Biophysica Acta24 citations Open access
Semantic Scholar
Structural and Functional Deviations in Disease-Associated p97 Mutants
Wai-Kwan Tang, D. Xia
2012Journal of Structural Biology21 citations Open access
Semantic Scholar
NADPH oxidase 1 mediates caerulein-induced pancreatic fibrosis in chronic pancreatitis
D. Xia, Bithika Halder, C. Godoy, A. Chakraborty +7 more
2019Free Radical Biology & Medicine19 citations Open access
Semantic Scholar
Structural basis for nucleotide-modulated p97 association with the ER membrane
Wai-Kwan Tang, Ting Zhang, Yi-Hong Ye, D. Xia
2017Cell Discovery19 citations Open access
Semantic Scholar
Hydrogen Bonding to the Substrate Is Not Required for Rieske Iron-Sulfur Protein Docking to the Quinol Oxidation Site of Complex III*
L. Esser, F. Zhou, Yihui Zhou, Yu-Mei Xiao +4 more
2016Journal of Biological Chemistry19 citations Open access
Semantic Scholar
Human-Mouse Chimeras With Normal Expression and Function Reveal That Major Domain Swapping is Tolerated by P-glycoprotein (ABCB1)
Kristen M. Pluchino, M. Hall, Janna K. Moen, E. Chufán +7 more
2016Biochemistry17 citations Open access
Semantic Scholar

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Chang-An Yu×12
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S. Ambudkar — researcher profile on SciRah

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