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X. Jian · SciRah

Researcher profile · Semantic Scholar

X. Jian

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X. Jian — researcher profile on SciRah

h-index: 20
Works: 50
Citations: 1,130

Most-cited papers

Small-molecule synergist of the Wnt/β-catenin signaling pathway
Qisheng Zhang, Michael B. Major, Shinichi Takanashi, Nathan D. Camp +8 more
2007Proceedings of the National Academy of Sciences of the United States of America124 citations Open access
Semantic Scholar
A BAR domain in the N terminus of the Arf GAP ASAP1 affects membrane structure and trafficking of epidermal growth factor receptor.
Z. Nie, D. Hirsch, Ruibai Luo, X. Jian +8 more
2006Current Biology95 citations Open access
Semantic Scholar
Autoinhibition of Arf GTPase-activating Protein Activity by the BAR Domain in ASAP1*
X. Jian, P. Brown, P. Schuck, J. Gruschus +3 more
2009Journal of Biological Chemistry73 citations Open access
Semantic Scholar
The Bombesin Receptor Subtypes Have Distinct G Protein Specificities*
X. Jian, E. Sainz, W. Clark, R. Jensen +2 more
1999Journal of Biological Chemistry63 citations Open access
Semantic Scholar
Molecular Basis for Cooperative Binding of Anionic Phospholipids to the PH Domain of the Arf GAP ASAP1
X. Jian, Wai-Kwan Tang, P. Zhai, N. Roy +8 more
2015Structure61 citations Open access
Semantic Scholar
Modifications to the C-terminus of Arf1 alter cell functions and protein interactions
X. Jian, M. Cavenagh, J. Gruschus, P. Randazzo +1 more
2010Traffic : the International Journal of Intracellular Transport57 citations Open access
Semantic Scholar
Small-molecule synergist of the Wnt/beta-catenin signaling pathway.
Qisheng Zhang, Michael B. Major, Shinichi Takanashi, Nathan D. Camp +8 more
2007Proceedings of the National Academy of Sciences of the United States of America54 citations
Semantic Scholar
Phosphatidylinositol-4-phosphate 5-Kinase and GEP100/Brag2 Protein Mediate Antiangiogenic Signaling by Semaphorin 3E-Plexin-D1 through Arf6 Protein*
A. Sakurai, X. Jian, Charity J. Lee, Yosif Manavski +4 more
2011Journal of Biological Chemistry53 citations Open access
Semantic Scholar
The Arf6 GTPase-activating Proteins ARAP2 and ACAP1 Define Distinct Endosomal Compartments That Regulate Integrin α5β1 Traffic*
Pei-Wen Chen, Ruibai Luo, X. Jian, P. Randazzo
2014Journal of Biological Chemistry50 citations Open access
Semantic Scholar
CIB2 regulates mTORC1 signaling and is essential for autophagy and visual function
Saumil Sethna, P. Scott, A. Giese, T. Duncan +7 more
2021Nature Communications42 citations Open access
Semantic Scholar
The N Termini of a-Subunit Isoforms Are Involved in Signaling between Vacuolar H+-ATPase (V-ATPase) and Cytohesin-2*
Hiroyuki Hosokawa, P. Dip, M. Merkulova, A. Bakulina +10 more
2013Journal of Biological Chemistry40 citations Open access
Semantic Scholar
The Arf GTPase-activating Protein, ASAP1, Binds Nonmuscle Myosin 2A to Control Remodeling of the Actomyosin Network*
Pei-Wen Chen, X. Jian, S. Heissler, K. Le +6 more
2016Journal of Biological Chemistry35 citations Open access
Semantic Scholar
The Pleckstrin Homology (PH) Domain of the Arf Exchange Factor Brag2 Is an Allosteric Binding Site*
X. Jian, J. Gruschus, E. Sztul, P. Randazzo
2012Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Membrane surface recognition by the ASAP1 PH domain and consequences for interactions with the small GTPase Arf1
O. Soubias, Shashank Pant, Frank Heinrich, Yue Zhang +8 more
2020Science Advances33 citations Open access
Semantic Scholar
ARAP2 Signals through Arf6 and Rac1 to Control Focal Adhesion Morphology*
Pei-Wen Chen, X. Jian, H. Yoon, P. Randazzo
2013Journal of Biological Chemistry33 citations Open access
Semantic Scholar
The ArfGAP ASAP1 Controls Actin Stress Fiber Organization via Its N-BAR Domain
Anjelika Gasilina, T. Vitali, Ruibai Luo, X. Jian +1 more
2019iScience32 citations Open access
Semantic Scholar
Independent and synergistic interaction of retinal G-protein subunits with bovine rhodopsin measured by surface plasmon resonance.
W. Clark, X. Jian, Loren Chen, J. Northup
2001Biochemical Journal31 citations Open access
Semantic Scholar
Gβγ Affinity for Bovine Rhodopsin Is Determined by the Carboxyl-terminal Sequences of the γ Subunit*
X. Jian, W. Clark, J. Kowalak, S. Markey +2 more
2001Journal of Biological Chemistry30 citations Open access
Semantic Scholar
Inhibition of Cytohesins Protects against Genetic Models of Motor Neuron Disease
J. Zhai, Lei Zhang, J. Mojsilovic-Petrovic, X. Jian +8 more
2015Journal of Neuroscience23 citations Open access
Semantic Scholar
Nucleotide exchange factors
J. Northup, X. Jian, P. Randazzo
2012Cellular Logistics22 citations Open access
Semantic Scholar
Novel C-terminal Motif within Sec7 Domain of Guanine Nucleotide Exchange Factors Regulates ADP-ribosylation Factor (ARF) Binding and Activation*
Jason Lowery, T. Szul, J. Seetharaman, X. Jian +12 more
2011Journal of Biological Chemistry17 citations Open access
Semantic Scholar
Phosphorylation Uncouples the Gastrin-releasing Peptide Receptor from Gq *
G. S. Kroog, X. Jian, Lorenzo H. Chen, J. Northup +1 more
1999Journal of Biological Chemistry16 citations Open access
Semantic Scholar
Small GTPase ARF6 is a coincidence detection code for RPH3A polarization in neutrophil polarization
Chunguang Ren, Qian-Ying Yuan, X. Jian, P. Randazzo +2 more
2020Journal of Immunology15 citations Open access
Semantic Scholar
Interaction of the N terminus of ADP-ribosylation factor with the PH domain of the GTPase-activating protein ASAP1 requires phosphatidylinositol 4,5-bisphosphate
N. Roy, X. Jian, O. Soubias, P. Zhai +10 more
2019Journal of Biological Chemistry14 citations Open access
Semantic Scholar
The small molecule inhibitor NAV-2729 has a complex target profile including multiple ADP-ribosylation factor regulatory proteins
E. Rosenberg, X. Jian, O. Soubias, H. Yoon +10 more
2023Journal of Biological Chemistry12 citations Open access
Semantic Scholar
Quantitative Analysis of Guanine Nucleotide Exchange Factors (GEFs) as Enzymes
P. Randazzo, X. Jian, Pei-Wen Chen, P. Zhai +2 more
2013Cellular Logistics12 citations Open access
Semantic Scholar
Approaches to Studying Arf GAPs in Cells: In Vitro Assay with Isolated Focal Adhesions
Pei-Wen Chen, X. Jian, Ruibai Luo, P. Randazzo
2012Current Protocols in Cell Biology12 citations Open access
Semantic Scholar
ARAP2 inhibits Akt independently of its effects on focal adhesions
Ruibai Luo, Pei-Wen Chen, Jean-Cheng Kuo, L. M. Miller Jenkins +3 more
2018Biology of the Cell9 citations Open access
Semantic Scholar
A lysine-rich cluster in the N-BAR domain of ARF GTPase-activating protein ASAP1 is necessary for binding and bundling actin filaments
Anjelika Gasilina, H. Yoon, X. Jian, Ruibai Luo +1 more
2022Journal of Biological Chemistry8 citations Open access
Semantic Scholar
Direct Functional Interaction of the Kinesin-13 Family Membrane Kinesin-like Protein 2A (Kif2A) and Arf GAP with GTP-binding Protein-like, Ankyrin Repeats and PH Domains1 (AGAP1)*♦
Ruibai Luo, Pei-Wen Chen, Michael J. Wagenbach, X. Jian +3 more
2016Journal of Biological Chemistry6 citations Open access
Semantic Scholar
Direct functional interaction of the kinesin-13 family member kinesin-like protein 2A (Kif2A) and Arf GAP with GTP-binding protein-like, ankyrin repeats and PH domains 1 (AGAP1).
Ruibai Luo, Pei-Wen Chen, Michael J. Wagenbach, X. Jian +3 more
2016Journal of Biological Chemistry6 citations Open access
Semantic Scholar
ASAP1 and ARF1 regulate myogenic differentiation in rhabdomyosarcoma by modulating TAZ activity
K. Hebron, Olivia L. Perkins, Angela Kim, X. Jian +6 more
2024Molecular Cancer Research4 citations Open access
Semantic Scholar
Gbetagamma affinity for bovine rhodopsin is determined by the carboxyl-terminal sequences of the gamma subunit.
X. Jian, W. Clark, J. Kowalak, S. Markey +2 more
2001Journal of Biological Chemistry4 citations
Semantic Scholar
ERK phosphorylation is dependent on cell adhesion in a subset of pediatric sarcoma cell lines.
H. Yoon, Ben Y. Maron, Sofia A Girald-Berlingeri, Anjelika Gasilina +6 more
2022Biochimica et biophysica acta. Molecular cell research3 citations Open access
Semantic Scholar
Enzymology and Regulation of ArfGAPs and ArfGEFs
P. Zhai, X. Jian, Ruibai Luo, P. Randazzo
20123 citations Open access
Semantic Scholar
Point mutations in Arf1 reveal cooperative effects of the N-terminal extension and myristate for GTPase-activating protein catalytic activity
Eric M. Rosenberg, X. Jian, O. Soubias, Rebekah A. Jackson +7 more
2023bioRxiv1 citations Open access
Semantic Scholar
CIB2 regulates autophagy via Rheb-mTORC1 signaling axis
Saumil Sethna, S. Bernstein, X. Jian, S. Riazuddin +3 more
2020bioRxiv1 citations Open access
Semantic Scholar
Autoinhibition of Arf GAP activity by the BAR domain in ASAP1
X. Jian, P. Brown, P. Schuck, J. Gruschus +3 more
20081 citations
Semantic Scholar
Erratum: Small-molecule synergist of the Wnt/β-catenin signaling pathway (Proceedings of the National Academy of Sciences of the United States of America (2007) 104, 18, (7444-7448) DOI: 10.1073/pnas.0702136104)
Qisheng Zhang, Michael B. Major, Shinichi Takanashi, Nathan D. Camp +8 more
20071 citations Open access
Semantic Scholar
Abstract 334: ASAP1’s role in regulating myogenic differentiation in fusion negative rhabdomyosarcoma
Angela Kim, K. Hebron, Olivia L. Perkins, X. Jian +3 more
2023Cancer Research0 citations
Semantic Scholar
Abstract A003: ASAP1 regulates myogenic differentiation in rhabdomyosarcoma by modulating YAP localization
K. Hebron, Olivia Feehan-Nelson, A. Kim, X. Jian +3 more
2022Clinical Cancer Research0 citations
Semantic Scholar
Abstract B32: ASAP1 regulates differentiation in myoblasts and PAX-FOXO1 fusion-negative rhabdomyosarcoma
K. Hebron, Olivia Feehan-Nelson, X. Jian, Sofia A. Girald +2 more
20200 citations
Semantic Scholar
The PH Domain of ASAP1 Binds N terminus of Arf1 in Presence of PIP2 for Efficient GTPase‐activating Protein Activity
N. Roy, P. Zhai, X. Jian, Lisa M. Jenkins +3 more
2019The FASEB Journal0 citations
Semantic Scholar
Interaction of the ASAP1 PH Domain with the N Terminus of ARF1 is Controlled by Conformational Switching
N. Roy, P. Zhai, X. Jian, L. M. Miller Jenkins +3 more
20180 citations Open access
Semantic Scholar
9 Enzymology and Regulation of ArfGAPs and ArfGEFs
P. Zhai, X. Jian, Ruibai Luo, P. Randazzo
20170 citations
Semantic Scholar
Simple in vitro assay of Arf GAPs and preparation of Arf proteins as substrates
Pei-Wen Chen, X. Jian, Ruibai Luo, P. Randazzo
2015Methods in Cell Biology0 citations Open access
Semantic Scholar
The Arf6 GTPase-activating Proteins ARAP2 and ACAP1 Define Distinct Endosomal Compartments That Regulate Integrin (cid:2) 5 (cid:3) 1 Traffic
Pei-Wen Chen, Ruibai Luo, X. Jian, P. Randazzo
20140 citations
Semantic Scholar
Focal Adhesion Morphology ARAP 2 Signals through Arf 6 and Rac 1 to Cell Biology
Pei-Wen Chen, X. Jian, H. Yoon, P. Randazzo
20130 citations
Semantic Scholar
Quantitative a nalysis of Guanine Nucleotide exchange Factors (G eFs) as e nzymes
X. Jian, P. Zhai, J. Northup
20130 citations
Semantic Scholar
V‐ATPase is a novel evolutionarily conserved cytohesin‐signaling receptor
Hiroyuki Hosokawa, P. Dip, M. Merkulova, A. Bakulina +7 more
20130 citations
Semantic Scholar

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