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M. Maurizi · SciRah

Researcher profile · Semantic Scholar

M. Maurizi

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M. Maurizi — researcher profile on SciRah

h-index: 56
Works: 139
Citations: 11K

Most-cited papers

Posttranslational quality control: folding, refolding, and degrading proteins.
S. Wickner, M. Maurizi, S. Gottesman
1999Science1,122 citations
Semantic Scholar
Protein quality control: triage by chaperones and proteases.
S. Gottesman, S. Wickner, M. Maurizi
1997Genes & Development573 citations Open access
Semantic Scholar
The RssB response regulator directly targets sigma(S) for degradation by ClpXP.
Yan-Ning Zhou, Susan Gottesman, Joel R. Hoskins, M. Maurizi +1 more
2001Genes & Development309 citations Open access
Semantic Scholar
Homology in structural organization between E. coli ClpAP protease and the eukaryotic 26 S proteasome.
M. Kessel, M. Maurizi, Bernard Kim, E. Kocsis +3 more
1995Journal of Molecular Biology295 citations Open access
Semantic Scholar
Enzymatic and Structural Similarities between theEscherichia coli ATP-dependent Proteases, ClpXP and ClpAP*
Régis Grimaud, M. Kessel, F. Beuron, A. Steven +1 more
1998Journal of Biological Chemistry283 citations Open access
Semantic Scholar
Unfolding and internalization of proteins by the ATP-dependent proteases ClpXP and ClpAP.
Satyendra K. Singh, Régis Grimaud, Joel R. Hoskins, S. Wickner +1 more
2000Proceedings of the National Academy of Sciences of the United States of America241 citations Open access
Semantic Scholar
ATP-dependent Degradation of CcdA by Lon Protease
L. van Melderen, Minh-Hoa Tran Thi, P. Lecchi, S. Gottesman +2 more
1996Journal of Biological Chemistry217 citations Open access
Semantic Scholar
Crystal Structure of ClpA, an Hsp100 Chaperone and Regulator of ClpAP Protease*
F. Guo, M. Maurizi, L. Esser, D. Xia
2002Journal of Biological Chemistry209 citations Open access
Semantic Scholar
The Catalytic Domain of Escherichia coli Lon Protease Has a Unique Fold and a Ser-Lys Dyad in the Active Site*
I. Botos, E. E. Melnikov, S. Cherry, J. Tropea +7 more
2004Journal of Biological Chemistry189 citations Open access
Semantic Scholar
ATP-dependent protease La (lon) from Escherichia coli.
A. Goldberg, R. Moerschell, C. Chung, M. Maurizi
1994Methods in Enzymology182 citations
Semantic Scholar
Visualization of substrate binding and translocation by the ATP-dependent protease, ClpXP.
Joaquín Ortega, Satyendra K. Singh, Tomokazu Ishikawa, M. Maurizi +1 more
2000Molecules and Cells181 citations Open access
Semantic Scholar
Acyldepsipeptide Antibiotics Induces the Formation of a Structured Axial Channel in ClpP: a Model for the ClpX/ClpA Bound State of ClpP
D. Li, Y. Chung, Melanie Gloyd, Ebenezer Joseph +6 more
2010Chemistry and Biology163 citations Open access
Semantic Scholar
Functional Domains of the ClpA and ClpX Molecular Chaperones Identified by Limited Proteolysis and Deletion Analysis*
Satyendra K. Singh, J. Różycki, Joaquín Ortega, Tomokazu Ishikawa +3 more
2001Journal of Biological Chemistry158 citations Open access
Semantic Scholar
Protein binding and unfolding by the chaperone ClpA and degradation by the protease ClpAP.
Joel R. Hoskins, Satyendra K. Singh, M. Maurizi, S. Wickner
2000Proceedings of the National Academy of Sciences of the United States of America157 citations Open access
Semantic Scholar
The role of the ClpA chaperone in proteolysis by ClpAP.
Joel R. Hoskins, M. Pak, M. Maurizi, S. Wickner
1998Proceedings of the National Academy of Sciences of the United States of America141 citations Open access
Semantic Scholar
At sixes and sevens: characterization of the symmetry mismatch of the ClpAP chaperone-assisted protease.
F. Beuron, M. Maurizi, D. Belnap, E. Kocsis +3 more
1998Journal of Structural Biology137 citations
Semantic Scholar
Functional Proteolytic Complexes of the Human Mitochondrial ATP-dependent Protease, hClpXP*
S. Kang, J. Ortega, S. Singh, Nan Wang +3 more
2002Journal of Biological Chemistry132 citations Open access
Semantic Scholar
Turnover of mitochondrial steroidogenic acute regulatory (StAR) protein by Lon protease: the unexpected effect of proteasome inhibitors.
Z. Granot, O. Kobiler, N. Melamed-Book, S. Eimerl +7 more
2007Molecular Endocrinology130 citations Open access
Semantic Scholar
Translocation pathway of protein substrates in ClpAP protease
Tomokazu Ishikawa, F. Beuron, M. Kessel, S. Wickner +2 more
2001Proceedings of the National Academy of Sciences of the United States of America129 citations Open access
Semantic Scholar
Human Mitochondrial ClpP Is a Stable Heptamer That Assembles into a Tetradecamer in the Presence of ClpX*
S. Kang, Mariana N. Dimitrova, J. Ortega, A. Ginsburg +1 more
2005Journal of Biological Chemistry123 citations Open access
Semantic Scholar
Crystallography and mutagenesis point to an essential role for the N-terminus of human mitochondrial ClpP.
S. Kang, M. Maurizi, M. Thompson, T. Mueser +1 more
2004Journal of Structural Biology117 citations Open access
Semantic Scholar
Subunit‐specific degradation of the UmuD/D′ heterodimer by the ClpXP protease: the role of trans recognition in UmuD′ stability
Martín Gonzalez, F. Rasulova, M. Maurizi, R. Woodgate
2000EMBO Journal117 citations Open access
Semantic Scholar
Six‐fold rotational symmetry of ClpQ, the E. coli homolog of the 20S proteasome, and its ATP‐dependent activator, ClpY
M. Kessel, Whi-fin Wu, S. Gottesman, E. Kocsis +2 more
1996FEBS Letters113 citations
Semantic Scholar
Crystal Structure of the Heterodimeric Complex of the Adaptor, ClpS, with the N-domain of the AAA+ Chaperone, ClpA*
F. Guo, L. Esser, S. Singh, M. Maurizi +1 more
2002Journal of Biological Chemistry108 citations Open access
Semantic Scholar
Crystal structure at 1.9A of E. coli ClpP with a peptide covalently bound at the active site.
A. Szyk, M. Maurizi
2006Journal of Structural Biology101 citations
Semantic Scholar
Slicing a protease: Structural features of the ATP‐dependent Lon proteases gleaned from investigations of isolated domains
T. Rotanova, I. Botos, E. E. Melnikov, F. Rasulova +3 more
2006Protein Science97 citations Open access
Semantic Scholar
Turnover of Endogenous SsrA-tagged Proteins Mediated by ATP-dependent Proteases in Escherichia coli*
Mark A Lies, M. Maurizi
2008Journal of Biological Chemistry96 citations Open access
Semantic Scholar
Crystal structure of Lon protease: molecular architecture of gated entry to a sequestered degradation chamber
S. Cha, Y. An, Chang-Ro Lee, H. Lee +7 more
2010EMBO Journal94 citations Open access
Semantic Scholar
Molecular properties of ClpAP protease of Escherichia coli: ATP-dependent association of ClpA and clpP.
M. Maurizi, Satyendra K. Singh, M. W. Thompson, M. Kessel +1 more
1998Biochemistry87 citations
Semantic Scholar
Role of the Heat Shock Protein DnaJ in the Lon-dependent Degradation of Naturally Unstable Proteins*
Y. Jubete, M. Maurizi, S. Gottesman
1996Journal of Biological Chemistry87 citations Open access
Semantic Scholar
Nucleotide‐dependent oligomerization of C1pB from Escherichia coli
M. Żółkiewski, M. Kessel, A. Ginsburg, M. Maurizi
1999Protein Science79 citations Open access
Semantic Scholar
Mutational analysis demonstrates different functional roles for the two ATP-binding sites in ClpAP protease from Escherichia coli.
Sudheer Kumar Singh, M. Maurizi
1994Journal of Biological Chemistry78 citations Open access
Semantic Scholar
Alternating translocation of protein substrates from both ends of ClpXP protease
J. Ortega, H. Lee, M. Maurizi, A. Steven
2002EMBO Journal76 citations Open access
Semantic Scholar
Crystal structure of the AAA + a domain of E . coli Lon protease at 1 . 9 A resolution
I. Botos, E. E. Melnikov, S. Cherry, A. G. Khalatova +6 more
200375 citations
Semantic Scholar
Protein binding and disruption by Clp/Hsp100 chaperones.
M. Maurizi, D. Xia
2004Structure69 citations Open access
Semantic Scholar
ClpA and ClpX ATPases bind simultaneously to opposite ends of ClpP peptidase to form active hybrid complexes.
J. Ortega, H. Lee, M. Maurizi, A. Steven
2004Journal of Structural Biology64 citations
Semantic Scholar
AAA proteins: in search of a common molecular basis
M. Maurizi, Chou-Chi H. Li
200163 citations Open access
Semantic Scholar
Crystallographic investigation of peptide binding sites in the N-domain of the ClpA chaperone.
D. Xia, L. Esser, S. Singh, F. Guo +1 more
2004Journal of Structural Biology59 citations
Semantic Scholar
ClpA and ClpP remain associated during multiple rounds of ATP-dependent protein degradation by ClpAP protease.
Satyendra K. Singh, F. Guo, M. Maurizi
1999Biochemistry59 citations
Semantic Scholar
Proteases and protein degradation inEscherichia coli
M. Maurizi
2005Experientia58 citations
Semantic Scholar
Concurrent Chaperone and Protease Activities of ClpAP and the Requirement for the N-terminal ClpA ATP Binding Site for Chaperone Activity*
M. Pak, Joel R. Hoskins, Satyendra K. Singh, M. Maurizi +1 more
1999Journal of Biological Chemistry56 citations Open access
Semantic Scholar
The N-terminal substrate-binding domain of ClpA unfoldase is highly mobile and extends axially from the distal surface of ClpAP protease.
T. Ishikawa, M. Maurizi, A. Steven
2004Journal of Structural Biology55 citations
Semantic Scholar
Crystal structure of the N‐terminal domain of E. coli Lon protease
Mi Li, F. Rasulova, E. E. Melnikov, T. Rotanova +3 more
2005Protein Science53 citations Open access
Semantic Scholar
Structure and Functional Properties of the Active Form of the Proteolytic Complex, ClpP1P2, from Mycobacterium tuberculosis*
Mi Li, Olga Kandror, T. Akopian, P. Dharkar +3 more
2016Journal of Biological Chemistry52 citations Open access
Semantic Scholar
The N-degradome of Escherichia coli
Matthew A. Humbard, S. Surkov, G. D. de Donatis, Lisa M. Jenkins +1 more
2013Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Local and Global Mobility in the ClpA AAA+ Chaperone Detected by Cryo-electron Microscopy: Functional Connotations
G. Effantin, T. Ishikawa, G. D. de Donatis, M. Maurizi +1 more
2010Structure45 citations Open access
Semantic Scholar
Binding of the ClpA Unfoldase Opens the Axial Gate of ClpP Peptidase*
G. Effantin, M. Maurizi, A. Steven
2010Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Degradation of L-glutamate dehydrogenase from Escherichia coli: allosteric regulation of enzyme stability.
M. Maurizi, F. Rasulova
2002Archives of Biochemistry and Biophysics38 citations
Semantic Scholar
ATP-dependent proteases: Docking of components in a bacterial complex
T. Ishikawa, M. Maurizi, D. Belnap, A. Steven
2000Nature37 citations
Semantic Scholar
Mitochondrial ClpP activity is required for cisplatin resistance in human cells
Yang Zhang, M. Maurizi
2015Biochimica et Biophysica Acta34 citations Open access
Semantic Scholar

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A. Steven×14
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A. Steven — researcher profile on SciRah
S. Wickner×8
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S. Wickner — researcher profile on SciRah
Satyendra K. Singh×8
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Satyendra K. Singh — researcher profile on SciRah
M. Kessel×7
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M. Kessel — researcher profile on SciRah

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F. Rasulova — researcher profile on SciRah

S. Gottesman×5

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S. Gottesman — researcher profile on SciRah

Joel R. Hoskins×5

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Joel R. Hoskins — researcher profile on SciRah

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J. Ortega — researcher profile on SciRah

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F. Guo — researcher profile on SciRah

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D. Xia — researcher profile on SciRah

E. E. Melnikov×4

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E. E. Melnikov — researcher profile on SciRah

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T. Rotanova — researcher profile on SciRah