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C. Coackley · SciRah

Researcher profile · Semantic Scholar

C. Coackley

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C. Coackley — researcher profile on SciRah

h-index: 18
Works: 31
Citations: 1,391

Most-cited papers

Cancer esearch apeutics , Targets , and Chemical Biology textual Synthetic Lethality of Cancer Cell Kill Based R he Tumor Microenvironment
Norm Nirma Thom, A. Chan, Isabel M. Pires, Zuzana Bencokova +9 more
2010205 citations
Semantic Scholar
Cardiolipin exposure on the outer mitochondrial membrane modulates α-synuclein
Tammy L. Ryan, Vladimir V. Bamm, Morgan G. Stykel, C. Coackley +7 more
2018Nature Communications191 citations Open access
Semantic Scholar
PTEN Deletion in Prostate Cancer Cells Does Not Associate With Loss of RAD51 Function: Implications for Radiotherapy and Chemotherapy
Michael Fraser, Helen Zhao, K. Luoto, Cecilia Lundin +7 more
2011Clinical Cancer Research148 citations Open access
Semantic Scholar
A novel poly(ADP-ribose) polymerase inhibitor, ABT-888, radiosensitizes malignant human cell lines under hypoxia.
Stanley K. Liu, C. Coackley, M. Krause, F. Jalali +2 more
2008Radiotherapy and Oncology130 citations
Semantic Scholar
MRE11 promotes AKT phosphorylation in direct response to DNA double-strand breaks
Michael Fraser, S. Harding, Helen Zhao, C. Coackley +2 more
2011Cell Cycle117 citations Open access
Semantic Scholar
Evidence for the direct binding of phosphorylated p53 to sites of DNA breaks in vivo.
S. A. Al Rashid, G. Dellaire, A. Cuddihy, F. Jalali +10 more
2005Cancer Research111 citations
Semantic Scholar
Cancer esearch apeutics , Targets , and Chemical Biology or Cell Kill by c-MYC Depletion : Role of MYC-Regulated R es that Control DNA Double-Strand Break Repair
R. Luoto, A. Meng, A. Wasylishen, Helen Zhao +3 more
201072 citations
Semantic Scholar
In vivo studies of the PARP inhibitor, AZD-2281, in combination with fractionated radiotherapy: An exploration of the therapeutic ratio.
C. Gani, C. Coackley, R. Kumareswaran, C. Schütze +3 more
2015Radiotherapy and Oncology63 citations
Semantic Scholar
α-Synuclein mutation impairs processing of endomembrane compartments and promotes exocytosis and seeding of α-synuclein pathology.
Morgan G. Stykel, Kayla M. Humphries, E. Kamski-Hennekam, Brodie Buchner-Duby +6 more
2021Cell Reports46 citations Open access
Semantic Scholar
Hypercapnia increases cerebral tissue oxygen tension in anesthetized rats
G. Hare, B. Kavanagh, C. Mazer, Kathryn M. Hum +4 more
2003Canadian Journal of Anaesthesia-journal Canadien D Anesthesie45 citations Open access
Semantic Scholar
Axonal pathology in hPSC-based models of Parkinson’s disease results from loss of Nrf2 transcriptional activity at the Map1b gene locus
Chris Czaniecki, Tammy L. Ryan, Morgan G. Stykel, Jennifer Drolet +7 more
2019Proceedings of the National Academy of Sciences of the United States of America41 citations Open access
Semantic Scholar
Tumor cell kill by c-MYC depletion: role of MYC-regulated genes that control DNA double-strand break repair.
K. Luoto, A. Meng, A. Wasylishen, Helen Zhao +3 more
2010Cancer Research37 citations Open access
Semantic Scholar
ATM-dependent phosphorylation of 53BP1 in response to genomic stress in oxic and hypoxic cells.
S. Harding, C. Coackley, R. Bristow
2011Radiotherapy and Oncology36 citations
Semantic Scholar
Efficacy of Combining GMX1777 with Radiation Therapy for Human Head and Neck Carcinoma
Hisayuki Kato, E. Ito, Wei Shi, N. Alajez +11 more
2010Clinical Cancer Research35 citations Open access
Semantic Scholar
Contextual Synthetic Lethality of Cancer Cell Kill Based on the Tumor Microenvironment
N. Chan, Isabel M Pires, Zuzana Bencokova, C. Coackley +8 more
2010Cancer Research32 citations Open access
Semantic Scholar
Protein-Protein Interactions Occur Between p53 Phosphoforms and ATM and 53BP1 at Sites of Exogenous DNA Damage
S. A. Al Rashid, S. Harding, C. Law, C. Coackley +1 more
2011Radiation Research20 citations
Semantic Scholar
WTp53 induction does not override MTp53 chemoresistance and radioresistance due to gain-of-function in lung cancer cells
A. Cuddihy, F. Jalali, C. Coackley, R. Bristow
2008Molecular Cancer Therapeutics19 citations Open access
Semantic Scholar
Docosahexanoic acid signals through the Nrf2–Nqo1 pathway to maintain redox balance and promote neurite outgrowth
Jennifer Drolet, Brodie Buchner-Duby, Morgan G. Stykel, C. Coackley +3 more
2021Molecular Biology of the Cell18 citations Open access
Semantic Scholar
Partial magic angle spinning NMR 1H, 13C, 15N resonance assignments of the flexible regions of a monomeric alpha-synuclein: conformation of C-terminus in the lipid-bound and amyloid fibril states
Justin Medeiros, Vladimir V. Bamm, Catherine Jany, C. Coackley +4 more
2021Biomolecular NMR Assignments11 citations
Semantic Scholar
Intracellular Accumulation of α-Synuclein Aggregates Promotes S-Nitrosylation of MAP1A Leading to Decreased NMDAR-Evoked Calcium Influx and Loss of Mature Synaptic Spines
Ryan D. Hallam, Brodie Buchner-Duby, Morgan G. Stykel, C. Coackley +1 more
2022Journal of Neuroscience10 citations Open access
Semantic Scholar
A Novel Poly(ADP-ribose) Polymerase Inhibitor, ABT-888, Sensitizes Malignant Human Cell Lines to Ionizing Radiation Under Oxia and Hypoxia
Stanley K. Liu, C. Coackley, R. Bristow
20073 citations Open access
Semantic Scholar
Cardiolipin exposure on the outer mitochondrial membrane modulates α‐synuclein proteostasis in hPSC‐derived Parkinson's Disease neurons
Scott D. Ryan, Tammy L. Ryan, Vladamir V. Bamm, Morgan G. Stykel +3 more
20181 citations
Semantic Scholar
Axonal pathology in hPSC‐based models of Parkinson's Disease results from loss of Nrf2‐transcriptional activity at the Map1b gene locus
Tammy L. Ryan, Jennifer Drolet, Keith Sherriff, C. Coackley +1 more
20180 citations
Semantic Scholar
Nrf2 Activation Rescues Dendritic Pathology in hPSC‐Derived And Primary Neuron Based Models of Parkinson's Disease
Jennifer Drolet, Chris Czaniecki, Tammy Ryan, Morgan G. Stykel +2 more
20180 citations
Semantic Scholar
OC-0487: Genetically engineered breast cancer mouse models to explore and target radioresistance
G. Borst, C. Coackley, H. Yücel, C. Guyader +6 more
20140 citations
Semantic Scholar
Ther Tum
R. Luoto, Helen Zhao, C. Coackley, Robert G. Bristow
20100 citations
Semantic Scholar
Abstract A115: Contextual synthetic lethality: Repair‐deficient hypoxic tumor cells are sensitized to poly(ADP‐ribose) polymerase (PARP) inhibition
N. Chan, Isabel M. Pires, Zuzana Bencokova, C. Coackley +7 more
20090 citations
Semantic Scholar
Renal expression of endothelial nitric oxide synthase after cpb in rat
F. Briet, G. Hare, K. Blight, Zhi-Lan Wang +5 more
20050 citations Open access
Semantic Scholar
In collaboration with the Canadian Anesthesiologists’ Society, the Canadian Journal of Anesthesia is proud to publish the best abstracts presented at the Annual Meeting of the Canadian Anesthesiologists’ Society held in Quebec City, Quebec, June 18–22, 2004
D. Campbell, T. Breen, S. Halpern, H. Muir +51 more
20040 citations
Semantic Scholar
Abstract
T. Chhina, Harry R. Lapierre, Zane S. Jackson, H. Leong-Poi +299 more
20040 citations Open access
Semantic Scholar
Neuroanesthesia and Intensive Care Hypercapnia increases cerebral tissue oxygen tension in anesthetized rats (L'hypercapnie augmente la tension en oxygène du tissu cérébral chez des rats anesthésiés)
Brian P. Kavanagh, C. Mazer, Kathryn M. Hum, Steve Y. Kim +3 more
20030 citations
Semantic Scholar

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