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A. Meng · SciRah

Researcher profile · Semantic Scholar

A. Meng

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A. Meng — researcher profile on SciRah

h-index: 19
Works: 58
Citations: 2,980

Most-cited papers

Spatial genomic heterogeneity within localized, multifocal prostate cancer
P. Boutros, Michael Fraser, N. Harding, R. de Borja +61 more
2015Nature Genetics481 citations Open access
Semantic Scholar
Down-Regulation of Rad51 and Decreased Homologous Recombination in Hypoxic Cancer Cells
R. Bindra, Paul J. Schaffer, A. Meng, Jennifer L. Woo +6 more
2004Molecular and Cellular Biology382 citations Open access
Semantic Scholar
Hypoxia-induced down-regulation of BRCA1 expression by E2Fs.
R. Bindra, S. Gibson, A. Meng, U. Westermark +5 more
2005Cancer Research346 citations Open access
Semantic Scholar
Genomic hallmarks of localized, non-indolent prostate cancer
Michael Fraser, Veronica Sabelnykova, T. Yamaguchi, L. Heisler +66 more
2017Nature287 citations
Semantic Scholar
Germline BRCA2 mutations drive prostate cancers with distinct evolutionary trajectories
Renea A. Taylor, Michael Fraser, J. Livingstone, S. M. Espiritu +24 more
2017Nature Communications223 citations Open access
Semantic Scholar
Hypoxia down-regulates DNA double strand break repair gene expression in prostate cancer cells.
A. Meng, F. Jalali, A. Cuddihy, N. Chan +3 more
2005Radiotherapy and Oncology203 citations
Semantic Scholar
A Prostate Cancer "Nimbosus": Genomic Instability and SChLAP1 Dysregulation Underpin Aggression of Intraductal and Cribriform Subpathologies.
M. Chua, Winnie W. Lo, M. Pintilie, J. Murgić +26 more
2017European Urology168 citations
Semantic Scholar
Chronic hypoxia compromises repair of DNA double-strand breaks to drive genetic instability
R. Kumareswaran, O. Ludkovski, A. Meng, J. Sykes +2 more
2012Journal of Cell Science132 citations Open access
Semantic Scholar
Copy number alterations of c‐MYC and PTEN are prognostic factors for relapse after prostate cancer radiotherapy
G. Zafarana, A. Ishkanian, C. Malloff, Jennifer A. Locke +13 more
2012Cancer128 citations Open access
Semantic Scholar
High‐resolution array CGH identifies novel regions of genomic alteration in intermediate‐risk prostate cancer
A. Ishkanian, Chad A. Mallof, J. Ho, A. Meng +8 more
2009The Prostate93 citations
Semantic Scholar
IDH mutation status in prostate cancer
A. F. Ghiam, R. Cairns, J. Thoms, A. Dal Pra +4 more
2012Oncogene72 citations Open access
Semantic Scholar
Cancer esearch apeutics , Targets , and Chemical Biology or Cell Kill by c-MYC Depletion : Role of MYC-Regulated R es that Control DNA Double-Strand Break Repair
R. Luoto, A. Meng, A. Wasylishen, Helen Zhao +3 more
201072 citations
Semantic Scholar
Alterations in DNA Repair Gene Expression under Hypoxia: Elucidating the Mechanisms of Hypoxia‐Induced Genetic Instability
R. Bindra, Paul J. Schaffer, A. Meng, Jennifer L. Woo +6 more
2005Annals of the New York Academy of Sciences72 citations
Semantic Scholar
TMPRSS2-ERG Status Is Not Prognostic Following Prostate Cancer Radiotherapy: Implications for Fusion Status and DSB Repair
A. Dal Pra, Emilie Lalonde, J. Sykes, Fiona Warde +16 more
2013Clinical Cancer Research55 citations
Semantic Scholar
NKX3.1 Haploinsufficiency Is Prognostic for Prostate Cancer Relapse following Surgery or Image-Guided Radiotherapy
Jennifer A. Locke, G. Zafarana, A. Ishkanian, M. Milosevic +13 more
2011Clinical Cancer Research45 citations
Semantic Scholar
Translating a Prognostic DNA Genomic Classifier into the Clinic: Retrospective Validation in 563 Localized Prostate Tumors.
Emilie Lalonde, R. Alkallas, M. Chua, Michael Fraser +25 more
2017European Urology43 citations
Semantic Scholar
Hypoxia disrupts the Fanconi anemia pathway and sensitizes cells to chemotherapy through regulation of UBE2T.
Chantal Ramaekers, T. van den Beucken, A. Meng, S. Kassam +3 more
2011Radiotherapy and Oncology41 citations Open access
Semantic Scholar
The receptor tyrosine kinase inhibitor amuvatinib (MP470) sensitizes tumor cells to radio- and chemo-therapies in part by inhibiting homologous recombination.
Helen Zhao, K. Luoto, A. Meng, R. Bristow
2011Radiotherapy and Oncology40 citations
Semantic Scholar
Tumor cell kill by c-MYC depletion: role of MYC-regulated genes that control DNA double-strand break repair.
K. Luoto, A. Meng, A. Wasylishen, Helen Zhao +3 more
2010Cancer Research37 citations Open access
Semantic Scholar
Determining the Impact of Spatial Heterogeneity on Genomic Prognostic Biomarkers for Localized Prostate Cancer.
H. Brastianos, J. Murgić, A. Salcedo, M. Chua +8 more
2020European Urology Oncology18 citations
Semantic Scholar
Allelic loss of the loci containing the androgen synthesis gene, StAR, is prognostic for relapse in intermediate‐risk prostate cancer
Jennifer A. Locke, G. Zafarana, C. Malloff, W. Lam +10 more
2012The Prostate13 citations
Semantic Scholar
Cyclic hypoxia does not alter RAD51 expression or PARP inhibitor cell kill in tumor cells.
R. Kumareswaran, N. Chaudary, Karolina Jaluba, A. Meng +4 more
2015Radiotherapy and Oncology11 citations
Semantic Scholar
Erratum: Copy number alterations of c-MYC and PTEN are prognostic factors for relapse after prostate cancer radiotherapy (Cancer (2012) 118 (4053-4062))
G. Zafarana, A. Ishkanian, C. Malloff, Jennifer A. Locke +13 more
201411 citations Open access
Semantic Scholar
Genomic Architecture of Prostate Cancer at Recurrence Following Radiation Therapy
M. Chua, A. Salcedo, A. Meng, Jingbin Zhang +5 more
20162 citations Open access
Semantic Scholar
PD-0300: NBN gain is predictive for adverse outcome following image-guided radiotherapy for localized prostate cancer
A. Berlin, Emilie Lalonde, G. Zafarana, J. Sykes +6 more
20142 citations
Semantic Scholar
Using NBN to predict biochemical relapse following image-guided radiotherapy (IGRT) for intermediate-risk prostate cancer (IR-PCa).
A. Berlin, Emilie Lalonde, G. Zafarana, J. Sykes +7 more
20142 citations
Semantic Scholar
218MO Comparison of a 22-gene genomic classifier (GC) with NCCN for risk stratification of Asian prostate cancers (PCa)
Wai W. Yee, A. Sim, K. Low, A. Meng +12 more
2020Annals of Oncology1 citations Open access
Semantic Scholar
The impact of intratumoral heterogeneity on prognostic biomarkers in localized prostate cancer.
H. Brastianos, J. Murgić, A. Salcedo, M. Chua +8 more
2019Journal of Clinical Oncology1 citations
Semantic Scholar
Investigation of a 22-gene genomic classifier (GC) for risk stratification and molecular subtyping in an Asian prostate cancer (PCa) cohort.
Wei Loong Sherman Yee, Wai-Yee Woo, A. Sim, K. Low +15 more
20210 citations
Semantic Scholar
39 Determination of the Impact of Intratumoural Heterogeneity on Prognostic Biomarkers in Localized Prostate Cancer
H. Brastianos, J. Murgić, A. Salcedo, M. Chua +6 more
2019Radiotherapy and Oncology0 citations Open access
Semantic Scholar
Abstract A28: Mutational landscape of TP53 in localized prostate cancer
O. Mahamud, M. Chua, S. Supiot, Emilie Lalonde +16 more
20170 citations
Semantic Scholar
Abstract 5860: Genomic architecture of prostate cancer at recurrence following radiotherapy
M. Chua, Erle M. Holgersen, Veronica Sabelnykova, A. Salcedo +5 more
20170 citations Open access
Semantic Scholar
Genomic architecture of radioresistant prostate cancer.
M. Chua, Erle M. Holgersen, Veronica Sabelnykova, A. Salcedo +5 more
20170 citations
Semantic Scholar
Prognostic value of copy-number alterations of the Cohesin complex in intermediate-risk prostate cancer recurrence.
J. So, M. Chua, Emilie Lalonde, O. Mahamud +16 more
20160 citations
Semantic Scholar
Prognostic Significance of Tonsil Expression and the Homologous Recombination Pathway in Intermediate-Risk Prostate Cancer Recurrence
J. So, M. Chua, Emilie Lalonde, A. Dal Pra +15 more
20160 citations
Semantic Scholar
Copy number alterations of P53, RB1, and MDM2 as prognostic markers in intermediate-risk prostate cancer.
O. Mahamud, M. Chua, Emilie Lalonde, J. So +16 more
20160 citations
Semantic Scholar
Abstract 4339: Prognostic significance of copy number alteration burden in unfavorable intermediate-risk prostate cancers harboring intraductal carcinoma and cribriform architecture
M. Chua, J. Murgić, M. Pintilie, Emilie Lalonde +19 more
20160 citations
Semantic Scholar
Copy number alterations of DNA mismatch repair (MMR) genes as novel prognostic markers in localised prostate cancer (CaP).
M. Chua, Emilie Lalonde, O. Mahamud, A. Berlin +16 more
20160 citations
Semantic Scholar
Combinatorial genomic and pathological indices for integrated stratification of unfavorable intermediate-risk prostate cancer.
M. Chua, J. Murgić, M. Pintilie, Emilie Lalonde +12 more
20160 citations
Semantic Scholar
227: Prognostic Significance of Tonsl Expression and the Homologous Recombination Pathway in Intermediate-Risk Prostate Cancer Recurrence
J. So, M. Chua, Emilie Lalonde, O. Mahamud +15 more
20160 citations Open access
Semantic Scholar
Spatio-genomic heterogeneity within localized, multi-focal prostate cancer
P. Boutros, Michael Fraser, N. Harding, R. de Borja +69 more
20150 citations
Semantic Scholar
Abstract 2966: The mutational landscape of localized gleason 6 and 7 prostate cancer
Michael Fraser, Veronica Sabelnykova, T. Yamaguchi, A. Meng +46 more
20150 citations
Semantic Scholar
Predictive Biomarkers and Personalized Medicine TMPRSS2-ERG Status Is Not Prognostic Following Prostate CancerRadiotherapy: Implications forFusionStatusandDSB Repair
A. Dal Pra, Emilie Lalonde, J. Sykes, Fiona Warde +16 more
20130 citations
Semantic Scholar
Abstract B129: Clinical implications of inter- and intra- prostatic heterogeneity.
Emilie Lalonde, P. Boutros, Michael Fraser, R. de Borja +20 more
20130 citations
Semantic Scholar
Radiotherapy : Implications for Fusion Status and DSB Repair Status Is Not Prognostic Following Prostate Cancer
A. Dal Pra, Emilie Lalonde, J. Sykes, Fiona Warde +16 more
20130 citations
Semantic Scholar
MC13-0009 A prognostic CNA signature sub-stratifies intermediate-risk prostate cancer
P. Boutros, Emilie Lalonde, A. Ishkanian, J. Sykes +15 more
20130 citations
Semantic Scholar
Abstract 2003: A molecular portrait of potentially curable prostate cancer.
Michael Fraser, R. de Borja, D. Trudel, N. Harding +33 more
20130 citations
Semantic Scholar
Genomic Instability in Common Fragile Sites (CFSs) Is Associated With Less Favorable Outcome in Patients With Intermediate-Risk Prostate Cancer (IR-CaP)
A. F. Ghiam, G. Zafarana, L. Emilie, J. Sykes +6 more
20130 citations Open access
Semantic Scholar
TMPRSS2-ERG status and biochemical recurrence following radiotherapy for intermediate-risk prostate cancer.
A. Dal Pra, Fiona Warde, A. Ishkanian, A. Meng +9 more
2012Journal of Clinical Oncology0 citations
Semantic Scholar
Abstract 3184: Whole genome sequencing of low-input fresh frozen prostate cancer biopsies
M. Sam, Taryne M. Chong, Amin Zia, Emilie Lalonde +23 more
20120 citations
Semantic Scholar

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