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C. Guyader · SciRah

Researcher profile · Semantic Scholar

C. Guyader

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C. Guyader — researcher profile on SciRah

h-index: 10
Works: 34
Citations: 1,175

Most-cited papers

A New Model of Patient Tumor-Derived Breast Cancer Xenografts for Preclinical Assays
E. Marangoni, A. Vincent-Salomon, N. Auger, A. Degeorges +13 more
2007Clinical Cancer Research425 citations
Semantic Scholar
Subunit composition of VRAC channels determines substrate specificity and cellular resistance to Pt-based anti-cancer drugs
R. Planells-Cases, Darius Lutter, C. Guyader, Nora M. Gerhards +14 more
2015EMBO Journal253 citations Open access
Semantic Scholar
Molecular profiling of patient-derived breast cancer xenografts
F. Reyal, C. Guyader, C. Decraene, C. Lucchesi +14 more
2012Breast Cancer Research183 citations Open access
Semantic Scholar
Modeling of response to endocrine therapy in a panel of human luminal breast cancer xenografts
P. Cottu, E. Marangoni, F. Assayag, P. de Cremoux +13 more
2012Breast Cancer Research and Treatment87 citations
Semantic Scholar
BRCA2-deficient sarcomatoid mammary tumors exhibit multidrug resistance.
J. Jaspers, Wendy M. P. J. Sol, A. Kersbergen, A. Schlicker +6 more
2015Cancer Research60 citations Open access
Semantic Scholar
Establishment and characterisation of a new breast cancer xenograft obtained from a woman carrying a germline BRCA2 mutation
L. Deplater, A. Laugé, C. Guyader, M. Poupon +12 more
2010British Journal of Cancer52 citations Open access
Semantic Scholar
Selected Alkylating Agents Can Overcome Drug Tolerance of G0-like Tumor Cells and Eradicate BRCA1-Deficient Mammary Tumors in Mice
M. Pajic, Sohvi Blatter, C. Guyader, M. Gonggrijp +7 more
2017Clinical Cancer Research30 citations Open access
Semantic Scholar
Potentiation of antitumour activity of docetaxel by combination with trastuzumab in a human prostate cancer xenograft model and underlying mechanisms
M. Legrier, S. Oudard, J. Judde, C. Guyader +5 more
2007British Journal of Cancer28 citations Open access
Semantic Scholar
Risk of Hormone Escape in a Human Prostate Cancer Model Depends on Therapy Modalities and Can Be Reduced by Tyrosine Kinase Inhibitors
C. Guyader, J. Céraline, É. Gravier, A. Morin +7 more
2012PLoS ONE19 citations Open access
Semantic Scholar
Haploid genetic screens identify genetic vulnerabilities to microtubule‐targeting agents
Nora M. Gerhards, V. Blomen, M. Mutlu, J. Nieuwenhuis +5 more
2018Molecular Oncology13 citations Open access
Semantic Scholar
Chemotherapy induces an immunosuppressive gene expression signature in residual BRCA1/p53-deficient mouse mammary tumors
Sohvi Blatter, N. Stokar-Regenscheit, A. Kersbergen, C. Guyader +1 more
20187 citations Open access
Semantic Scholar
Hormone escape is associated with genomic instability in a human prostate cancer model
M. Legrier, C. Guyader, J. Céraline, B. Dutrillaux +3 more
2009International Journal of Cancer6 citations Open access
Semantic Scholar
A preclinical therapeutic schedule optimizing docetaxel plus estramustine administration in prostate cancer
A. Dahmani, L. Deplater, C. Guyader, J. Fontaine +9 more
2010Anti-Cancer Drugs5 citations
Semantic Scholar
[New targeted therapies in hormone-refractory prostate cancer].
S. Oudard, E. Banu, F. Scotté, P. Beuzeboc +2 more
2007Bulletin du Cancer3 citations
Semantic Scholar
Abstract 736: Combining PD1- and CTLA4-inhibiting antibodies with cisplatin or PARP inhibition in an attempt to eradicate BRCA1-deficient mouse mammary tumors
Sohvi Blatter, C. Guyader, Asli Küçükosmanoglu, Stephan Freriks +3 more
20151 citations
Semantic Scholar
Molecular profiling of patient-derived breast cancer xenografts
F. Reyal, C. Guyader, C. Decraene, C. Lucchesi +14 more
2012Breast Cancer Research1 citations Open access
Semantic Scholar
Abstract 3275: Molecular characterization of human breast cancer xenografts reveals a strong genomic and gene expression stability
F. Reyal, C. Guyader, C. Decraene, C. Lucchesi +12 more
20101 citations
Semantic Scholar
Abstract S6-7: Establishment and Characterization of Human Luminal Breast Cancer Xenografts
P. Cottu, F. Assayag, L. Deplater, C. Elbaz +10 more
20101 citations
Semantic Scholar
Abstracts the Metastasis Research Society-American Association for Cancer Research Conference on Metastasis
Jane A. Cipollone, M. Graves, M. Koebel, J. Nielsen +17 more
2008Clinical and Experimental Metastasis1 citations
Semantic Scholar
Targeting drug tolerance of residual BRCA1-mutated mouse mammary tumours
Sohvi Blatter, M. Pajic, C. Guyader, M. Gonggrijp +7 more
2019Journal of Comparative Pathology0 citations
Semantic Scholar
Peer Review #1 of "A systematic review of the validity of patient derived xenograft (PDX) models: the implications for translational research and personalised medicine (v0.1)"
A. Collins, S. Lang, M. Baker, P. Ball +296 more
20180 citations Open access
Semantic Scholar
Targeting G0-like Residual Cells in a Mouse Model for BRCA1-deficient Mammary Tumours
Sohvi Blatter, Nadine Regenscheit, C. Guyader, A. Kucukosmanoglu +3 more
20170 citations
Semantic Scholar
Abstract 3607: Loss-of-function screens using haploid KBM7 and HAP1 cells to identify mechanisms of anti-cancer drug resistance
Nora M. Gerhards, C. Guyader, V. Blomen, Asli Küçükosmanoglu +6 more
20150 citations
Semantic Scholar
1 BRCA 2-deficient sarcomatoid mammary tumors exhibit multi-drug resistance 1
J. Jaspers, Wendy M. P. J. Sol, A. Kersbergen, A. Schlicker +6 more
20140 citations
Semantic Scholar
169: Homologous recombination deficiency and radio-curability in mouse models for BRCA1/2-deficient breast cancer
S. Rottenberg, G. Borst, A. Gasparini, M. Barazas +5 more
20140 citations
Semantic Scholar
OC-0487: Genetically engineered breast cancer mouse models to explore and target radioresistance
G. Borst, C. Coackley, H. Yücel, C. Guyader +6 more
20140 citations
Semantic Scholar
Doxorubicin sensitivity and acquired resistance of Pgp-and BRCA 1-deficient mouse mammary tumors
Wendy M. P. J. Sol, A. Kersbergen, J. D. de Ronde, Nikola Banishki +4 more
20120 citations
Semantic Scholar
Abstract 1603: Primary breast cancer xenografts maintain the molecular profiles of corresponding patients’ tumors and recapitulate a part of stroma microenvironment
F. Reyal, C. Guyader, C. Decraene, C. Lucchesi +12 more
20110 citations
Semantic Scholar
276 Establishment and characterization of human luminal breast cancer xenografts
F. Assayag, P. Cottu, C. Elbaz, E. Marangoni +6 more
20100 citations
Semantic Scholar
214 Molecular characterization of patient tumour-derived breast cancer xenografts shows a strong genomic and gene expression stability
E. Marangoni, F. Reyal, C. Guyader, C. Decraene +6 more
20100 citations
Semantic Scholar
Abstract A27: Efficacy of estramustine + docetaxel in docetaxel‐resistant human prostate cancer xenograft: a preclinical model of docetaxel resistance reversion
A. Dahmani, L. Deplater, C. Guyader, J. Fontaine +9 more
20090 citations
Semantic Scholar
Characterization of a novel breast cancer xenograft and the corresponding cell line derived from a BRCA2 germ-line mutation carrier patient’s tumor.
L. Deplater, N. Auger, F. Assayag, P. de Cremoux +9 more
20080 citations
Semantic Scholar
Hormone therapy modality influences the delay and frequency of hormone escape of prostate cancer in a xenograft human model
C. Guyader, S. Oudard, M. Princivalle, J. Céraline +3 more
20070 citations
Semantic Scholar
P16 Biological profiles of two ERBB2-amplified human breast cancer xenografts diversely sensitive to Trastuzumab
L. Deplater, E. Marangoni, F. Assayag, N. Auger +6 more
20070 citations
Semantic Scholar

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