Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

R. Cowling · SciRah

Researcher profile · Semantic Scholar

R. Cowling

Share profile

R. Cowling — researcher profile on SciRah

h-index: 24
Works: 46
Citations: 4,224

Most-cited papers

piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
K. Woltjen, Iacovos P. Michael, P. Mohseni, Ridham Desai +9 more
2009Nature1,896 citations Open access
Semantic Scholar
Evaluation of fluorescence-based thermal shift assays for hit identification in drug discovery.
Mei-Chu Lo, A. Aulabaugh, G. Jin, R. Cowling +3 more
2004Analytical Biochemistry680 citations
Semantic Scholar
Adipose vascular endothelial growth factor regulates metabolic homeostasis through angiogenesis.
H. Sung, K. Doh, Joe Eun Son, J. G. Park +10 more
2013Cell Metabolism301 citations Open access
Semantic Scholar
Acylguanidines as Small-Molecule β-Secretase Inhibitors
D. Cole, E. Manas, J. Stock, J. Condon +22 more
200693 citations Open access
Semantic Scholar
Substrate specificity and inducibility of TACE (tumour necrosis factor alpha-converting enzyme) revisited: the Ala-Val preference, and induced intrinsic activity.
R. Black, J. Doedens, Rajeev M. Mahimkar, Richard S. Johnson +13 more
2003Biochemical Society Symposium77 citations
Semantic Scholar
Acylguanidine inhibitors of β-secretase: Optimization of the pyrrole ring substituents extending into the S1 and S3 substrate binding pockets
D. Cole, J. Stock, R. Chopra, R. Cowling +18 more
200873 citations
Semantic Scholar
The discovery of anthranilic acid-based MMP inhibitors. Part 2: SAR of the 5-position and P1(1) groups.
J. Levin, J. Chen, M. Du, M. Hogan +17 more
2001Bioorganic & Medicinal Chemistry Letters68 citations Open access
Semantic Scholar
Anthranilate sulfonamide hydroxamate TACE inhibitors. Part 2: SAR of the acetylenic P1' group.
J. Levin, J.-M. Chen, M. Du, F. C. Nelson +10 more
2002Bioorganic & Medicinal Chemistry Letters66 citations Open access
Semantic Scholar
X-ray spectroscopy of the iron site in soybean lipoxygenase-1: changes in coordination upon oxidation or addition of methanol.
R. Scarrow, Milton Trimitsis, C. Buck, Geoffrey N. Grove +2 more
1994Biochemistry64 citations
Semantic Scholar
Synthesis and Structure−Activity Relationship of N-Substituted 4-Arylsulfonylpiperidine-4-hydroxamic Acids as Novel, Orally Active Matrix Metalloproteinase Inhibitors for the Treatment of Osteoarthritis
V. Aranapakam, J. Davis, G. Grosu, J. Baker +17 more
200362 citations Open access
Semantic Scholar
A switch in numb isoforms is a critical step in cortical development
M. Bani-Yaghoub, Chris J. Kubu, R. Cowling, Jennifer A. Rochira +3 more
2007Developmental Dynamics61 citations Open access
Semantic Scholar
Synthesis and Structure−Activity Relationship of α-Sulfonylhydroxamic Acids as Novel, Orally Active Matrix Metalloproteinase Inhibitors for the Treatment of Osteoarthritis
V. Aranapakam, G. Grosu, J. Davis, Baihua Hu +11 more
200360 citations Open access
Semantic Scholar
Thiophene substituted acylguanidines as BACE1 inhibitors.
W. Fobare, W. Solvibile, A. Robichaud, M. Malamas +8 more
2007Bioorganic & Medicinal Chemistry Letters59 citations Open access
Semantic Scholar
Characterization of (2R, 3S)-2-([[4-(2-butynyloxy)phenyl]sulfonyl]amino)-N,3-dihydroxybutanamide, a potent and selective inhibitor of TNF-alpha converting enzyme.
Yuhua Zhang, M. Hegen, Jun Xu, J. Keith +15 more
2004International Immunopharmacology59 citations
Semantic Scholar
A Continuous Fluorimetric Assay for Tumor Necrosis Factor-α Converting Enzyme
G. Jin, Xin-Yi Huang, R. Black, M. Wolfson +4 more
200258 citations
Semantic Scholar
Structural characterization of alkyl and peroxyl radicals in solutions of purple lipoxygenase.
M. Nelson, R. Cowling, S. Seitz
1994Biochemistry57 citations
Semantic Scholar
Enzyme-bound pentadienyl and peroxyl radicals in purple lipoxygenase.
M. Nelson, S. Seitz, R. Cowling
1990Biochemistry54 citations
Semantic Scholar
Acetylenic TACE inhibitors. Part 1. SAR of the acyclic sulfonamide hydroxamates.
J. Levin, James M. Chen, Katherine Cheung, D. Cole +20 more
2003Bioorganic & Medicinal Chemistry Letters45 citations Open access
Semantic Scholar
Two novel human NUMB isoforms provide a potential link between development and cancer
Aldona A. Karaczyn, M. Bani-Yaghoub, R. Tremblay, Chris J. Kubu +7 more
2010Neural Development44 citations Open access
Semantic Scholar
The discovery of anthranilic acid-based MMP inhibitors. Part 1: SAR of the 3-position.
J. Levin, M. Du, J. Dijoseph, L. Killar +9 more
2001Bioorganic & Medicinal Chemistry Letters41 citations Open access
Semantic Scholar
The discovery of anthranilic acid-based MMP inhibitors. Part 3: incorporation of basic amines.
J. Levin, J.-M. Chen, M. Du, F. C. Nelson +16 more
2001Bioorganic & Medicinal Chemistry Letters32 citations Open access
Semantic Scholar
Synthesis and SAR of bicyclic heteroaryl hydroxamic acid MMP and TACE inhibitors.
A. Zask, Y. Gu, J. Albright, X. Du +16 more
2003Bioorganic & Medicinal Chemistry Letters31 citations Open access
Semantic Scholar
Benzodiazepine inhibitors of the MMPs and TACE.
F. C. Nelson, Efren Delos-Santos, J. Levin, James M. Chen +9 more
2002Bioorganic & Medicinal Chemistry Letters31 citations Open access
Semantic Scholar
Observation of a peroxyl radical in samples of purple lipoxygenase
M. Nelson, R. Cowling
199029 citations
Semantic Scholar
Discovery and initial optimization of 5,5'-disubstituted aminohydantoins as potent beta-secretase (BACE1) inhibitors.
P. Nowak, D. Cole, A. Aulabaugh, J. Bard +20 more
2010Bioorganic & Medicinal Chemistry Letters24 citations Open access
Semantic Scholar
3,4-Dihydropyrimido(1,2-a)indol-10(2H)-ones as potent non-peptidic inhibitors of caspase-3.
L. Havran, Dan C. Chong, W. Childers, P. Dollings +13 more
2009Bioorganic & Medicinal Chemistry21 citations Open access
Semantic Scholar
A continuous fluorimetric assay for tumor necrosis factor-alpha converting enzyme.
G. Jin, Xin-Yi Huang, R. Black, M. Wolfson +4 more
2002Analytical Biochemistry21 citations
Semantic Scholar
Synthesis and SAR of bis-statine based peptides as BACE 1 inhibitors.
Baihua Hu, K. Fan, K. Bridges, R. Chopra +7 more
2004Bioorganic & Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
Heteroaryl and cycloalkyl sulfonamide hydroxamic acid inhibitors of matrix metalloproteinases.
J. Levin, Yan-Song Gu, F. C. Nelson, Arie Zask +12 more
2001Bioorganic & Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
Acylguanidines as small-molecule beta-secretase inhibitors.
D. Cole, E. Manas, J. Stock, J. Condon +22 more
2006Journal of Medicinal Chemistry17 citations Open access
Semantic Scholar
Insulin acts as a myogenic differentiation signal for neural stem cells with multilineage differentiation potential
M. Bani-Yaghoub, Stephen E. Kendall, D. P. Moore, S. Bellum +5 more
2004Development17 citations Open access
Semantic Scholar
Acylguanidine inhibitors of beta-secretase: optimization of the pyrrole ring substituents extending into the S1' substrate binding pocket.
L. Jennings, D. Cole, J. Stock, M. N. Sukhdeo +17 more
2008Bioorganic & Medicinal Chemistry Letters14 citations
Semantic Scholar
A novel approach to identifying beta-secretase inhibitors: bis-statine peptide mimetics discovered using structure and spot synthesis.
K. Bridges, R. Chopra, Laura Lin, K. Svenson +14 more
2006Peptides11 citations
Semantic Scholar
Structure and kinetics of formation of catechol complexes of ferric soybean lipoxygenase-1.
M. Nelson, B. A. Brennan, D. Chase, R. Cowling +2 more
1995Biochemistry10 citations
Semantic Scholar
Mapping of NRAGE domains reveals clues to cell viability in BMP signaling
Jennifer A. Rochira, R. Cowling, J. Himmelfarb, T. Adams +1 more
2010Apoptosis8 citations Open access
Semantic Scholar
Bovine liver dihydropyrimidine amidohydrolase: pH dependencies of inactivation by chelators and steady-state kinetic properties.
Myoung Hee Lee, R. Cowling, E. Sander, D. W. Pettigrew
1986Archives of Biochemistry and Biophysics8 citations
Semantic Scholar
A colormetric assay for catechol-O-methyltransferase.
K. Bailey, R. Cowling, E. Tan, Daniel Webb
2004Bioorganic & Medicinal Chemistry1 citations
Semantic Scholar
Explorer piggyBac transposition reprograms fibroblasts to induced pluripotent stem cells
K. Woltjen, Iacovos P. Michael, P. Mohseni, Ridham Desai +9 more
20130 citations
Semantic Scholar
Fluorescence Resonance Energy Transfer Reveals Key Binding Domains of Neurotrophin Receptor-Interacting Melanoma-Associated Antigen Homolog in Bone Morphogenetic Protein-Mediated Apoptosis
Jennifer A. Rochira, R. Cowling, J. Himmelfarb, S. Hess +1 more
20090 citations Open access
Semantic Scholar
A switch in numb isoforms is a critical step in cortical development
M. Bani-Yaghoub, Chris J. Kubu, R. Cowling, Jennifer A. Rochira +3 more
20070 citations
Semantic Scholar
Structure-function Analysis of NRAGE : A Protein Involved in Developmental Neural Apoptosis
R. Cowling
20060 citations
Semantic Scholar
Crystal structure of catalytic domain of TNF-alpha converting enzyme (TACE) with inhibitor
J. Levin, James M. Chen, L. Laakso, T. DuMila +9 more
20050 citations
Semantic Scholar
Thiomorpholine sulfonamide hydroxamic acid-based TACE inhibitors
L. Laakso, J. Levin, M. Du, G. Jin +6 more
20030 citations
Semantic Scholar
BUTYNYL ETHER DERIVATIVES AS INHIBITORS OF TACE
J. Levin, Xuemei Du, J. Albright, James M. Chen +13 more
20030 citations
Semantic Scholar
Fatty acid radicals and the mechanism of soybean lipoxygenase.
M. Nelson, R. Cowling, S. Seitz
19930 citations
Semantic Scholar
Silhouette photography of polyacrylamide slab gels.
R. Bidigare, R. Cowling, D. W. Pettigrew
1984Analytical Biochemistry0 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

G. Jin×22
Invite
G. Jin — researcher profile on SciRah
J. Levin×13
Invite
J. Levin — researcher profile on SciRah
J. Skotnicki×13
Invite
J. Skotnicki — researcher profile on SciRah
A. Sung×11
Invite
A. Sung — researcher profile on SciRah

×9

Invite

J. Bard — researcher profile on SciRah

Invite

R. Black — researcher profile on SciRah

Invite

L. Killar — researcher profile on SciRah

Invite

R. Chopra — researcher profile on SciRah

J. Ellingboe×8

Invite

J. Ellingboe — researcher profile on SciRah

Invite

J. Dijoseph — researcher profile on SciRah

Invite

M. Sharr — researcher profile on SciRah

Invite

M. Malamas — researcher profile on SciRah