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K. Woltjen · SciRah

Researcher profile · Semantic Scholar

K. Woltjen

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K. Woltjen — researcher profile on SciRah

h-index: 38
Works: 115
Citations: 9,440

Most-cited papers

Robust In Vitro Induction of Human Germ Cell Fate from Pluripotent Stem Cells.
Kotaro Sasaki, Shihori Yokobayashi, Tomonori Nakamura, I. Okamoto +17 more
2015Cell Stem Cell501 citations Open access
Semantic Scholar
Premature termination of reprogramming in vivo leads to cancer development through altered epigenetic regulation.
Kotaro Ohnishi, Katsunori Semi, Takuya Yamamoto, M. Shimizu +11 more
2014Cell455 citations Open access
Semantic Scholar
An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming.
M. Gabut, Payman Samavarchi-Tehrani, Xinchen Wang, Valentina Slobodeniuc +14 more
2011Cell391 citations Open access
Semantic Scholar
The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis
K. Imamura, Y. Izumi, Akira Watanabe, Kayoko Tsukita +32 more
2017Science Translational Medicine234 citations Open access
Semantic Scholar
Engineering the AAVS1 locus for consistent and scalable transgene expression in human iPSCs and their differentiated derivatives.
Fabian Oceguera-Yañez, Shin-Il Kim, Tomoko Matsumoto, Ghee Wan Tan +7 more
2016Methods222 citations Open access
Semantic Scholar
Efficient and Reproducible Myogenic Differentiation from Human iPS Cells: Prospects for Modeling Miyoshi Myopathy In Vitro
A. Tanaka, K. Woltjen, K. Miyake, A. Hotta +13 more
2013PLoS ONE217 citations Open access
Semantic Scholar
Efficient TALEN construction and evaluation methods for human cell and animal applications
T. Sakuma, Sayaka Hosoi, K. Woltjen, Ken-ichi T. Suzuki +11 more
2013Genes to Cells213 citations
Semantic Scholar
Capturing human trophoblast development with naive pluripotent stem cells in vitro.
Shingo Io, Mio Kabata, Yoshiki Iemura, Katsunori Semi +16 more
2021Cell Stem Cell212 citations Open access
Semantic Scholar
iPSC-Based Compound Screening and In Vitro Trials Identify a Synergistic Anti-amyloid β Combination for Alzheimer's Disease.
T. Kondo, K. Imamura, Misato Funayama, Kayoko Tsukita +11 more
2017Cell Reports187 citations Open access
Semantic Scholar
Evolutionarily Distinctive Transcriptional and Signaling Programs Drive Human Germ Cell Lineage Specification from Pluripotent Stem Cells.
Yoji Kojima, Kotaro Sasaki, Shihori Yokobayashi, Y. Sakai +8 more
2017Cell Stem Cell172 citations Open access
Semantic Scholar
Recapitulating the human segmentation clock with pluripotent stem cells
Mitsuhiro Matsuda, Yoshihiro Yamanaka, Maya Uemura, M. Osawa +18 more
2020Nature164 citations Open access
Semantic Scholar
Cell-type-specific genome editing with a microRNA-responsive CRISPR–Cas9 switch
Moe Hirosawa, Y. Fujita, C. Parr, Karin Hayashi +4 more
2017Nucleic Acids Research98 citations Open access
Semantic Scholar
Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway.
D. Gallagher, Andreea Norman, Cameron L. Woodard, Guang Yang +10 more
2013Cell Stem Cell96 citations Open access
Semantic Scholar
Inducible Transgene Expression in Human iPS Cells Using Versatile All-in-One piggyBac Transposons.
Shin-Il Kim, Fabian Oceguera-Yañez, C. Sakurai, M. Nakagawa +2 more
2016Methods in molecular biology95 citations
Semantic Scholar
Synthetic lateral inhibition governs cell-type bifurcation with robust ratios
Mitsuhiro Matsuda, Makito Koga, K. Woltjen, E. Nishida +1 more
2015Nature Communications84 citations Open access
Semantic Scholar
Optimization of the proliferation and persistency of CAR T cells derived from human induced pluripotent stem cells
Tatsuki Ueda, Sara Shiina, S. Iriguchi, S. Terakura +16 more
2022Nature Biomedical Engineering80 citations Open access
Semantic Scholar
Hybrid Cellular Metabolism Coordinated by Zic3 and Esrrb Synergistically Enhances Induction of Naive Pluripotency.
Masamitsu Sone, N. Morone, Tomonori Nakamura, A. Tanaka +7 more
2017Cell Metabolism80 citations Open access
Semantic Scholar
Hypoblast from human pluripotent stem cells regulates epiblast development
Takumi Okubo, N. Rivron, Mio Kabata, Hideki Masaki +12 more
2023Nature79 citations Open access
Semantic Scholar
Mutant IDH1 Dysregulates the Differentiation of Mesenchymal Stem Cells in Association with Gene-Specific Histone Modifications to Cartilage- and Bone-Related Genes
Yong-Hui Jin, Hassan Elalaf, Makoto Watanabe, Sakura Tamaki +10 more
2015PLoS ONE69 citations Open access
Semantic Scholar
In vivo reprogramming drives Kras-induced cancer development
H. Shibata, Shingo Komura, Yosuke Yamada, Nao Sankoda +11 more
2018Nature Communications68 citations Open access
Semantic Scholar
Skin health and biological aging
D. Furman, Johan Auwerx, A. Bulteau, George M. Church +14 more
2025Nature Aging66 citations
Semantic Scholar
Nuclease‐mediated genome editing: At the front‐line of functional genomics technology
T. Sakuma, K. Woltjen
2014Development, Growth and Differentiation66 citations
Semantic Scholar
Transgene-free production of pluripotent stem cells using piggyBac transposons.
K. Woltjen, R. Hämäläinen, M. Kibschull, Maria Mileikovsky +1 more
2011Methods in molecular biology62 citations
Semantic Scholar
Microhomology-assisted scarless genome editing in human iPSCs
Shin-Il Kim, Tomoko Matsumoto, Harunobu Kagawa, Michiko Nakamura +7 more
2018Nature Communications59 citations Open access
Semantic Scholar
Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells
A. Yamashita, Shi-Ying Liu, K. Woltjen, B. Thomas +6 more
2013Scientific Reports46 citations Open access
Semantic Scholar
Correction: Efficient and Reproducible Myogenic Differentiation from Human iPS Cells: Prospects for Modeling Miyoshi Myopathy In Vitro
A. Tanaka, K. Woltjen, K. Miyake, A. Hotta +13 more
2013PLoS ONE45 citations Open access
Semantic Scholar
Synergistic gene editing in human iPS cells via cell cycle and DNA repair modulation
Thomas L. Maurissen, K. Woltjen
2020Nature Communications43 citations Open access
Semantic Scholar
SS18-SSX, the Oncogenic Fusion Protein in Synovial Sarcoma, Is a Cellular Context-Dependent Epigenetic Modifier
Sakura Tamaki, M. Fukuta, Kazuya Sekiguchi, Yong-Hui Jin +9 more
2015PLoS ONE43 citations Open access
Semantic Scholar
Beta‐cell replacement strategies for diabetes
T. Kieffer, K. Woltjen, Kenji Osafune, D. Yabe +1 more
2017Journal of Diabetes Investigation40 citations Open access
Semantic Scholar
Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations
Janin Grajcarek, Jean Monlong, Yoko Nishinaka-Arai, Michiko Nakamura +7 more
2019Nature Communications39 citations Open access
Semantic Scholar
Directed Myogenic Differentiation of Human Induced Pluripotent Stem Cells.
Emi Shoji, K. Woltjen, H. Sakurai
2016Methods in molecular biology39 citations
Semantic Scholar
KLF4 N-Terminal Variance Modulates Induced Reprogramming to Pluripotency
Shin-Il Kim, Fabian Oceguera-Yañez, Ryoko Hirohata, Sara Linker +5 more
2015Stem Cell Reports39 citations Open access
Semantic Scholar
DMRT1-mediated reprogramming drives development of cancer resembling human germ cell tumors with features of totipotency
Jumpei Taguchi, H. Shibata, Mio Kabata, Masaki Kato +16 more
2021Nature Communications36 citations Open access
Semantic Scholar
Srf destabilizes cellular identity by suppressing cell-type-specific gene expression programs
Takashi Ikeda, Takafusa Hikichi, Hisashi Miura, H. Shibata +10 more
2018Nature Communications35 citations Open access
Semantic Scholar
Reprogramming Roadblocks Are System Dependent
Eleni Chantzoura, Stavroula Skylaki, S. Ménendez, Shin-Il Kim +5 more
2015Stem Cell Reports35 citations Open access
Semantic Scholar
Cell-type dependent enhancer binding of the EWS/ATF1 fusion gene in clear cell sarcomas
Shingo Komura, Kenji Ito, Sho Ohta, Tomoyo Ukai +17 more
2019Nature Communications31 citations Open access
Semantic Scholar
De Novo DNA Methylation at Imprinted Loci during Reprogramming into Naive and Primed Pluripotency
Masaki Yagi, Mio Kabata, Tomoyo Ukai, Sho Ohta +9 more
2019Stem Cell Reports30 citations Open access
Semantic Scholar
PhiC31 integrase facilitates genetic approaches combining multiple recombinases.
C. Monetti, Koichiro Nishino, Steffen Biechele, Puzheng Zhang +3 more
2011Methods26 citations
Semantic Scholar
Epithelial expression of Gata4 and Sox2 regulates specification of the squamous–columnar junction via MAPK/ERK signaling in mice
Nao Sankoda, Wataru Tanabe, A. Tanaka, H. Shibata +9 more
2021Nature Communications25 citations Open access
Semantic Scholar
Cellular context-dependent consequences of Apc mutations on gene regulation and cellular behavior
Kyoichi Hashimoto, Yosuke Yamada, Katsunori Semi, Masaki Yagi +9 more
2017Proceedings of the National Academy of Sciences of the United States of America22 citations Open access
Semantic Scholar
An EWS-FLI1-Induced Osteosarcoma Model Unveiled a Crucial Role of Impaired Osteogenic Differentiation on Osteosarcoma Development
Shingo Komura, Katsunori Semi, Fumiaki Itakura, H. Shibata +6 more
2016Stem Cell Reports22 citations Open access
Semantic Scholar
Programmable mammalian translational modulators by CRISPR-associated proteins
Shunsuke Kawasaki, Hiroki Ono, Moe Hirosawa, T. Kuwabara +4 more
2021bioRxiv20 citations Open access
Semantic Scholar
OVOL1 Influences the Determination and Expansion of iPSC Reprogramming Intermediates
Harunobu Kagawa, Ren Shimamoto, Shin-Il Kim, Fabian Oceguera-Yañez +3 more
2019Stem Cell Reports20 citations Open access
Semantic Scholar
Differentiation of pluripotent stem cells for modeling human skin development and potential applications
Fabian Oceguera-Yañez, Alfonso Ávila-Robinson, K. Woltjen
2022Frontiers in Cell and Developmental Biology19 citations Open access
Semantic Scholar
Modeling mutation-specific arrhythmogenic phenotypes in isogenic human iPSC-derived cardiac tissues
Thomas L. Maurissen, Masahide Kawatou, Víctor López-Dávila, K. Minatoya +2 more
2024Scientific Reports15 citations Open access
Semantic Scholar
A disease-specific iPS cell resource for studying rare and intractable diseases
M. Saito, M. Osawa, Nao Tsuchida, Kotaro Shiraishi +7 more
2023Inflammation and Regeneration14 citations Open access
Semantic Scholar
Novel Calmodulin Variant p.E46K Associated With Severe Catecholaminergic Polymorphic Ventricular Tachycardia Produces Robust Arrhythmogenicity in Human Induced Pluripotent Stem Cell–Derived Cardiomyocytes
Jing-Shan Gao, T. Makiyama, Yuta Yamamoto, Takuya Kobayashi +25 more
2023Circulation: Arrhythmia and Electrophysiology14 citations
Semantic Scholar
The oncogene-dependent resistance to reprogramming unveils cancer therapeutic targets.
K. Ito, Kohei Nagata, Sho Ohta, Yutaka Matsuda +13 more
2022Cell Reports14 citations Open access
Semantic Scholar
N-Terminal Amino Acids Determine KLF4 Protein Stability in 2A Peptide-Linked Polycistronic Reprogramming Constructs
A. Reinhardt, Harunobu Kagawa, K. Woltjen
2020Stem Cell Reports14 citations Open access
Semantic Scholar
Identification of target genes of synovial sarcoma-associated fusion oncoprotein using human pluripotent stem cells.
Kazuo Hayakawa, M. Ikeya, M. Fukuta, K. Woltjen +6 more
2013Biochemical and Biophysical Research Communications - BBRC13 citations
Semantic Scholar

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