S. Babu

Most-cited papers

1. Discovery of an Orally Available, Brain Penetrant BACE1 Inhibitor that Affords Robust CNS Aβ Reduction

   A. Stamford, Jack D. Scott, Sarah W. Li, S. Babu +23 more

   2012ACS Medicinal Chemistry Letters97 citations Open access

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2. Rational design of novel, potent piperazinone and imidazolidinone BACE1 inhibitors.

   J. Cumming, T. Le, S. Babu, C. Carroll +24 more

   2008Bioorganic & Medicinal Chemistry Letters54 citations Open access

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3. Piperazine sulfonamide BACE1 inhibitors: design, synthesis, and in vivo characterization.

   J. Cumming, S. Babu, Ying Huang, C. Carrol +19 more

   2010Bioorganic & Medicinal Chemistry Letters50 citations Open access

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4. Preparation of 3-acetyl-2-hydroxyindoles via rhodium carbenoid aromatic carbon-hydrogen insertion

   N. Etkin, S. Babu, Catherine J. Fooks, T. Durst

   199050 citations

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5. Intramolecular rhodium carbenoid insertions into aromatic C—H bonds. Preparation of 1,3-dihydrothiophene 2,2-dioxides fused onto aromatic rings

   S. Babu, M. Hrytsak, T. Durst

   198926 citations

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6. Discovery and SAR of biaryl piperidine MCH1 receptor antagonists through solid-phase encoded combinatorial synthesis.

   T. Guo, Y. Shao, G. Qian, L. Rokosz +5 more

   2005Bioorganic & Medicinal Chemistry Letters16 citations Open access

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7. ErratumErratum to “Rational design of novel, potent piperazinone and imidazolidinone BACE1 inhibitors” [Bioorg. Med. Chem. Lett. 18 (2008) 3236–3241]

   J. Cumming, T. Le, S. Babu, C. Carroll +24 more

   20084 citations

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8. P3‐274: The plant‐derived polyphenol tannic acid mitigates Alzheimer‐like pathology

   L. Hyde, P. Leach, Qi Zhang, Giuseppe Terracina +16 more

   20102 citations

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9. P3‐299: Chronic administration of a novel BACE inhibitor reduced brain Aβ levels and mature plaques and modestly improved cognition in transgenic CRND8‐APPswe/ind mice

   L. Hyde, R. D. Del Vecchio, Tatiana M. Kazdoba, Ronald Manning +9 more

   20101 citations Open access

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10. BACE-1 inhibitors of cyclic amines having a substituent benzamide.

    S. Babu, S. Chackalamannil, J. Cumming, T. Guo +11 more

    20040 citations

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11. Part~A. Synthesis of optically active alpha-substituted acids. Part~B. The use of rhodium carbenoid reactions in organic synthesis.

    S. Babu

    19910 citations

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12. Preparation of 3-Acetyl-2-hydroxyindoles via Rhodium Carbenoid Aromatic C-H Insertion.

    N. Etkin, S. Babu, C. J. Fooks, T. Durst

    19900 citations

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13. Intramolecular Rhodium Carbenoid Insertions into Aromatic C-H Bonds. Preparation of 1,3-Dihydrothiophene 2,2-Dioxides Fused onto Aromatic Rings.

    S. Babu, M. Hrytsak, T. Durst

    19890 citations

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