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Nadine H. Elowe · SciRah

Researcher profile · Semantic Scholar

Nadine H. Elowe

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Nadine H. Elowe — researcher profile on SciRah

h-index: 16
Works: 25
Citations: 980

Most-cited papers

High-Throughput Screening Identifies Inhibitors of the SARS Coronavirus Main Proteinase
Jan E. Blanchard, Nadine H. Elowe, C. Huitema, Pascal D. Fortin +3 more
2004Chemistry and Biology185 citations Open access
Semantic Scholar
An allosteric inhibitor of substrate recognition by the SCFCdc4 ubiquitin ligase
S. Orlicky, Xiaojing Tang, Victor Neduva, Nadine H. Elowe +3 more
2010Nature Biotechnology151 citations Open access
Semantic Scholar
Biochemical characterization of cholesteryl ester transfer protein inhibitors
M. Ranalletta, Kathleen K. Bierilo, Ying Chen, D. Milot +17 more
2010Journal of Lipid Research101 citations Open access
Semantic Scholar
Ultrasensitive ATP detection using firefly luciferase entrapped in sugar-modified sol-gel-derived silica.
J. Cruz-Aguado, Yang Chen, Zheng Zhang, Nadine H. Elowe +2 more
2004Journal of the American Chemical Society84 citations
Semantic Scholar
SAR around (l)-S-adenosyl-l-homocysteine, an inhibitor of human DNA methyltransferase (DNMT) enzymes.
O. Saavedra, L. Isakovic, David B. Llewellyn, Lijie Zhan +12 more
2009Bioorganic & Medicinal Chemistry Letters57 citations Open access
Semantic Scholar
Constrained (l-)-S-adenosyl-l-homocysteine (SAH) analogues as DNA methyltransferase inhibitors.
L. Isakovic, O. Saavedra, David B. Llewellyn, S. Claridge +12 more
2009Bioorganic & Medicinal Chemistry Letters56 citations Open access
Semantic Scholar
An in vitro screen of bacterial lipopolysaccharide biosynthetic enzymes identifies an inhibitor of ADP-heptose biosynthesis.
G. D. de Leon, Nadine H. Elowe, K. Koteva, M. Valvano +1 more
2006Chemistry and Biology55 citations Open access
Semantic Scholar
Small-molecule screening made simple for a difficult target with a signaling nucleic acid aptamer that reports on deaminase activity.
Nadine H. Elowe, R. Nutiu, A. Allali‐Hassani, Jonathan Cechetto +3 more
2006Angewandte Chemie52 citations
Semantic Scholar
Inhibitors of bacterial cystathionine beta-lyase: leads for new antimicrobial agents and probes of enzyme structure and function.
L. Ejim, Jan E. Blanchard, K. Koteva, Rachael Sumerfield +5 more
2007Journal of Medicinal Chemistry45 citations Open access
Semantic Scholar
Experimental Screening of Dihydrofolate Reductase Yields a “Test Set” of 50,000 Small Molecules for a Computational Data-Mining and Docking Competition
Nadine H. Elowe, Jan E. Blanchard, Jonathan Cechetto, E. Brown
2005Journal of biomolecular screening31 citations Open access
Semantic Scholar
Cystathionine beta-lyase is important for virulence of Salmonella enterica serovar Typhimurium.
L. Ejim, Vanessa M. D'Costa, Nadine H. Elowe, J. Loredo-Osti +2 more
2004Infection and Immunity30 citations
Semantic Scholar
Functional annotation of putative aminoglycoside antibiotic modifying proteins in Mycobacterium tuberculosis H37Rv.
Kari-ann Draker, D. Boehr, Nadine H. Elowe, Theresa J Noga +1 more
2003Journal of antibiotics (Tokyo. 1968)23 citations Open access
Semantic Scholar
Side-chain determinants of biopolymer function during selection and replication
P. A. Lichtor, Zhen Chen, Nadine H. Elowe, Jonathan C. Chen +1 more
2019Nature Chemical Biology19 citations Open access
Semantic Scholar
TAILS Identifies Candidate Substrates and Biomarkers of ADAMTS7, a Therapeutic Protease Target in Coronary Artery Disease
Bryan T. MacDonald, Hasmik Keshishian, Charles C. Mundorff, A. Arduini +12 more
2021bioRxiv18 citations Open access
Semantic Scholar
Novel, highly potent systemic glucokinase activators for the treatment of Type 2 Diabetes Mellitus.
Jiayi Xu, Songnian Lin, R. W. Myers, G. Addona +22 more
2017Bioorganic & Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
Point mutations at the catalytic site of PCSK9 inhibit folding, autoprocessing, and interaction with the LDL receptor
C. Garvie, Cara Fraley, Nadine H. Elowe, Elizabeth Culyba +4 more
2016Protein Science18 citations Open access
Semantic Scholar
Discovery of orally active hepatoselective glucokinase activators for treatment of Type II Diabetes Mellitus.
Jiayi Xu, Songnian Lin, R. W. Myers, M. Trujillo +22 more
2017Bioorganic & Medicinal Chemistry Letters13 citations Open access
Semantic Scholar
BAY-9835: Discovery of the First Orally Bioavailable ADAMTS7 Inhibitor
D. Meibom, Pierre Wasnaire, Kristin Beyer, Andreas Broehl +17 more
2024Journal of Medicinal Chemistry9 citations Open access
Semantic Scholar
Rare, Damaging DNA Variants in CORIN and Risk of Coronary Artery Disease: Insights from Functional Genomics and Large-scale Sequencing Analyses
Min-Xian Wang, Vivian S. Lee-Kim, D. Atri, Nadine H. Elowe +13 more
2021Circulation Genomic and Precision Medicine9 citations Open access
Semantic Scholar
High-Throughput Screening at McMaster University: Automation in Academe
Jonathan Cechetto, Nadine H. Elowe, Jan E. Blanchard, E. Brown
20044 citations Open access
Semantic Scholar
Development of a novel, sensitive cell‐based corin assay
Pascal Lambertz, Laura Theisen, Natalie Längst, C. Garvie +6 more
2019Biochemical Pharmacology2 citations
Semantic Scholar
Abstract PR002: Functional screens identify a role for CHK1 in early nucleotide excision repair
I. Khan, Michelle Melanson, Myungsun Shin, I. Stelter +5 more
2024Cancer Research0 citations
Semantic Scholar
Identification of a new Corin atrial natriuretic peptide-converting enzyme substrate: Agouti-signaling protein (ASIP)
Bryan T. MacDonald, Nadine H. Elowe, C. Garvie, V. Kaushik +1 more
2023bioRxiv0 citations Open access
Semantic Scholar
Publisher Correction: Side chain determinants of biopolymer function during selection and replication
P. A. Lichtor, Zhen Chen, Nadine H. Elowe, Jonathan C. Chen +1 more
2019Nature Chemical Biology0 citations Open access
Semantic Scholar
Role of PDZ4 Domain of PDZK1 in the Regulation of Cholesterol Metabolism via the Hepatic HDL Receptor SR‐BI
O. Kocher, G. Birrane, J. Halford, Rinku Pal +5 more
20150 citations
Semantic Scholar

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