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J. Grimbergen · SciRah

Researcher profile · Semantic Scholar

J. Grimbergen

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J. Grimbergen — researcher profile on SciRah

h-index: 33
Works: 68
Citations: 3,757

Most-cited papers

Replication-Deficient Human Adenovirus Type 35 Vectors for Gene Transfer and Vaccination: Efficient Human Cell Infection and Bypass of Preexisting Adenovirus Immunity
R. Vogels, D. Zuijdgeest, Richard van Rijnsoever, Eric Hartkoorn +19 more
2003Journal of Virology489 citations Open access
Semantic Scholar
Apoptin induces apoptosis in human transformed and malignant cells but not in normal cells.
A. A. Danen-van Oorschot, D. Fischer, J. Grimbergen, B. Klein +6 more
1997Proceedings of the National Academy of Sciences of the United States of America265 citations Open access
Semantic Scholar
Exploiting the Natural Diversity in Adenovirus Tropism for Therapy and Prevention of Disease
M. Havenga, A. Lemckert, O. Ophorst, M. van Meijer +12 more
2002Journal of Virology204 citations Open access
Semantic Scholar
Calpainopathy-a survey of mutations and polymorphisms.
I. Richard, C. Roudaut, A. Sáenz, R. Pogue +19 more
1999American Journal of Human Genetics194 citations Open access
Semantic Scholar
Protective Function of Transcription Factor TR3 Orphan Receptor in Atherogenesis: Decreased Lesion Formation in Carotid Artery Ligation Model in TR3 Transgenic Mice
E. Arkenbout, V. de Waard, M. V. van Bragt, T. V. van Achterberg +4 more
2002Circulation181 citations Open access
Semantic Scholar
Membrane-type matrix metalloproteinase-mediated angiogenesis in a fibrin-collagen matrix.
A. Collen, R. Hanemaaijer, F. Lupu, P. Quax +5 more
2003Blood168 citations Open access
Semantic Scholar
Novel Replication-Incompetent Vector Derived from Adenovirus Type 11 (Ad11) for Vaccination and Gene Therapy: Low Seroprevalence and Non-Cross-Reactivity with Ad5
L. Holterman, R. Vogels, R. van der Vlugt, M. Sieuwerts +14 more
2004Journal of Virology154 citations Open access
Semantic Scholar
Anti–MCP-1 Gene Therapy Inhibits Vascular Smooth Muscle Cells Proliferation and Attenuates Vein Graft Thickening Both In Vitro and In Vivo
A. Schepers, D. Eefting, P. Bonta, J. Grimbergen +6 more
2006Arteriosclerosis, Thrombosis and Vascular Biology148 citations Open access
Semantic Scholar
Improved Adenovirus Vectors for Infection of Cardiovascular Tissues
M. Havenga, A. Lemckert, J. Grimbergen, R. Vogels +4 more
2001Journal of Virology140 citations Open access
Semantic Scholar
Elevated plasma factor VIII in a mouse model of low-density lipoprotein receptor-related protein deficiency.
N. Bovenschen, J. Herz, J. Grimbergen, P. Lenting +3 more
2003Blood128 citations Open access
Semantic Scholar
Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of TIMP-1 and TIMP-3
W. H. van der Laan, P. Quax, C. Seemayer, L. Huisman +8 more
2003Gene Therapy121 citations Open access
Semantic Scholar
Stimulation of tissue-type plasminogen activator gene expression by sodium butyrate and trichostatin A in human endothelial cells involves histone acetylation.
J. Arts, M. Lansink, J. Grimbergen, K. Toet +1 more
1995Biochemical Journal115 citations Open access
Semantic Scholar
Factor XIII stiffens fibrin clots by causing fiber compaction
N. A. Kurniawan, J. Grimbergen, J. Koopman, G. Koenderink
2014Journal of Thrombosis and Haemostasis105 citations Open access
Semantic Scholar
Generation of a novel replication-incompetent adenoviral vector derived from human adenovirus type 49: manufacture on PER.C6 cells, tropism and immunogenicity.
A. Lemckert, J. Grimbergen, Shirley Smits, Eric Hartkoorn +7 more
2006Journal of General Virology89 citations Open access
Semantic Scholar
Adenoviral Expression of a Urokinase Receptor–Targeted Protease Inhibitor Inhibits Neointima Formation in Murine and Human Blood Vessels
P. Quax, M. Lamfers, J. H. Lardenoye, J. Grimbergen +6 more
2001Circulation81 citations
Semantic Scholar
TR3 Orphan Receptor Is Expressed in Vascular Endothelial Cells and Mediates Cell Cycle Arrest
E. Arkenbout, M. V. van Bragt, E. Eldering, C. van Bree +4 more
2003Arteriosclerosis, Thrombosis and Vascular Biology77 citations
Semantic Scholar
Involvement of membrane-type matrix metalloproteinases (MT-MMPs) in capillary tube formation by human endometrial microvascular endothelial cells: role of MT3-MMP.
M. Plaisier, K. Kapiteijn, P. Koolwijk, Catherine Fijten +6 more
2004Journal of Clinical Endocrinology and Metabolism73 citations Open access
Semantic Scholar
Inhibition of Complement Component C3 Reduces Vein Graft Atherosclerosis in Apolipoprotein E3–Leiden Transgenic Mice
A. Schepers, M. D. de Vries, C. J. van Leuven, J. Grimbergen +4 more
2006Circulation66 citations Open access
Semantic Scholar
Vascular endothelial growth factor overexpression in ischemic skeletal muscle enhances myoglobin expression in vivo.
V. van Weel, M. Deckers, J. Grimbergen, K. V. van Leuven +6 more
2004Circulation Research65 citations
Semantic Scholar
Fibrinogen Marburg: a homozygous case of dysfibrinogenemia, lacking amino acids A alpha 461-610 (Lys 461 AAA-->stop TAA)
J. Koopman, F. Haverkate, J. Grimbergen, R. Egbring +1 more
199261 citations Open access
Semantic Scholar
Binding of human urokinase-type plasminogen activator to its receptor: residues involved in species specificity and binding.
P. Quax, J. Grimbergen, Mirian Lansink, A. Bakker +4 more
1998Arteriosclerosis, Thrombosis and Vascular Biology59 citations Open access
Semantic Scholar
Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of a cell surface-targeted plasmin inhibitor.
W. H. van der Laan, T. Pap, H. Ronday, J. Grimbergen +8 more
2000Arthritis & Rheumatism55 citations Open access
Semantic Scholar
The effect of interleukin-10 knock-out and overexpression on neointima formation in hypercholesterolemic APOE*3-Leiden mice.
D. Eefting, A. Schepers, M. D. de Vries, Nuno M. M. Pires +7 more
2007Atherosclerosis47 citations
Semantic Scholar
Genistein reduces tumor necrosis factor alpha-induced plasminogen activator inhibitor-1 transcription but not urokinase expression in human endothelial cells.
V. van Hinsbergh, M. Vermeer, P. Koolwijk, J. Grimbergen +1 more
1994Blood45 citations
Semantic Scholar
Adenoviral Activin A Expression Prevents Intimal Hyperplasia in Human and Murine Blood Vessels by Maintaining the Contractile Smooth Muscle Cell Phenotype
M. Engelse, J. H. Lardenoye, Jolanda M. Neele, J. Grimbergen +5 more
2002Circulation Research43 citations Open access
Semantic Scholar
Role of c-Jun and proximal phorbol 12-myristate-13-acetate-(PMA)-responsive elements in the regulation of basal and PMA-stimulated plasminogen-activator inhibitor-1 gene expression in HepG2.
J. Arts, J. Grimbergen, Piter J. Bosma, H. Rahmsdorf +1 more
1996European Journal of Biochemistry43 citations
Semantic Scholar
Aberrant fibrin formation and cross-linking of fibrinogen Nieuwegein, a variant with a shortened Aalpha-chain, alters endothelial capillary tube formation.
A. Collen, A. Maas, T. Kooistra, F. Lupu +6 more
2001Blood42 citations
Semantic Scholar
Gene Transfer of the Urokinase-Type Plasminogen Activator Receptor-Targeted Matrix Metalloproteinase Inhibitor TIMP-1.ATF Suppresses Neointima Formation More Efficiently Than Tissue Inhibitor of Metalloproteinase-1
M. Lamfers, J. Grimbergen, M. C. Aalders, M. Havenga +4 more
2002Circulation Research41 citations Open access
Semantic Scholar
Fibrinogen Caracas V, an Abnormal Fibrinogen with an Aα 532 Ser→Cys Substitution Associated with Thrombosis
R. Marchi, U. Lundberg, J. Grimbergen, J. Koopman +4 more
2000Thrombosis and Haemostasis37 citations
Semantic Scholar
On the role of c-Jun in the induction of PAI-1 gene expression by phorbol ester, serum, and IL-1alpha in HepG2 cells.
J. Arts, J. Grimbergen, K. Toet, T. Kooistra
1999Arteriosclerosis, Thrombosis and Vascular Biology37 citations Open access
Semantic Scholar
Vascular Endothelial Growth Factor Overexpression in Ischemic Skeletal Muscle Enhances Myoglobin Expression In Vivo
V. van Weel, M. Deckers, J. Grimbergen, K. V. van Leuven +6 more
200436 citations
Semantic Scholar
Inhibition of Accelerated Atherosclerosis in Vein Grafts by Placement of External Stent in ApoE*3-Leiden Transgenic Mice
J. H. Lardenoye, M. D. de Vries, J. Grimbergen, L. Havekes +5 more
2002Arteriosclerosis, Thrombosis and Vascular Biology36 citations Open access
Semantic Scholar
In vivo suppression of restenosis in balloon-injured rat carotid artery by adenovirus-mediated gene transfer of the cell surface-directed plasmin inhibitor ATF.BPTI
M. Lamfers, J. H. Lardenoye, M. D. de Vries, M. C. Aalders +4 more
2001Gene Therapy36 citations
Semantic Scholar
Involvement of furin-like proprotein convertases in the arterial response to injury.
J. Sluijter, R. Verloop, W. Pulskens, E. Velema +5 more
2005Cardiovascular Research31 citations Open access
Semantic Scholar
Recombinant fibrinogen reveals the differential roles of α‐ and γ‐chain cross‐linking and molecular heterogeneity in fibrin clot strain‐stiffening
I. Piechocka, N. A. Kurniawan, J. Grimbergen, J. Koopman +1 more
2017Journal of Thrombosis and Haemostasis29 citations Open access
Semantic Scholar
The mutation in fibrinogen Bicêtre II (gamma Asn308-->Lys) does not affect the binding of t-PA and plasminogen to fibrin.
P. Grailhe, C. Boyer-Neumann, F. Haverkate, J. Grimbergen +2 more
1993Blood Coagulation and Fibrinolysis26 citations Open access
Semantic Scholar
A novel urokinase receptor-targeted inhibitor for plasmin and matrix metalloproteinases suppresses vein graft disease.
D. Eefting, L. Seghers, J. Grimbergen, M. D. de Vries +5 more
2010Cardiovascular Research23 citations
Semantic Scholar
In vivo suppression of vein graft disease by nonviral, electroporation-mediated, gene transfer of tissue inhibitor of metalloproteinase-1 linked to the amino terminal fragment of urokinase (TIMP-1.ATF), a cell-surface directed matrix metalloproteinase inhibitor.
D. Eefting, M. D. de Vries, J. Grimbergen, J. Karper +2 more
2010Journal of Vascular Surgery23 citations Open access
Semantic Scholar
Prolonged In Vivo Gene Silencing by Electroporation-Mediated Plasmid Delivery of Small Interfering RNA
D. Eefting, J. Grimbergen, M. D. de Vries, V. van Weel +6 more
2007Human Gene Therapy23 citations
Semantic Scholar
Simultaneous detection of NOS-3 protein expression and nitric oxide production using a flow cytometer.
M. Havenga, B. V. Van Dam, B. S. Groot, J. Grimbergen +3 more
2001Analytical Biochemistry20 citations
Semantic Scholar
Fibrinogen reduction and coagulation in cardiac surgery: an investigational study
C. Gielen, J. Grimbergen, R. Klautz, J. Koopman +1 more
2015Blood Coagulation and Fibrinolysis19 citations
Semantic Scholar
Hydrodynamic characterization of recombinant human fibrinogen species
B. Raynal, B. Cardinali, J. Grimbergen, A. Profumo +3 more
2013Thrombosis Research16 citations Open access
Semantic Scholar
Adenoviral Gene Transfer of a u-PA Receptor-binding Plasmin Inhibitor and Green Fluorescent Protein: Inhibition of Migration and Visualization of Expression
M. Lamfers, M. Wijnberg, J. Grimbergen, L. Huisman +5 more
2000Thrombosis and Haemostasis14 citations Open access
Semantic Scholar
Fibrinogen γ′ promotes host survival during Staphylococcus aureus septicemia in mice
Oscar A Negrón, M. Weggeman, J. Grimbergen, Emily G. Clark +4 more
2023Journal of Thrombosis and Haemostasis12 citations Open access
Semantic Scholar
Adenoviral delivery of a constitutively active retinoblastoma mutant inhibits neointima formation in a human explant model for vein graft disease.
M. Lamfers, M. C. Aalders, J. Grimbergen, M. D. de Vries +3 more
2002Vascular pharmacology11 citations
Semantic Scholar
TR 3 Orphan Receptor Is Expressed in Vascular Endothelial Cells and Mediates Cell Cycle Arrest
E. Arkenbout, M. V. van Bragt, E. Eldering, C. van Bree +4 more
200310 citations
Semantic Scholar
Cartilage invasion by rheumatoid synovial fibroblasts in vivo is inhibited by gene transfer of a cell surface-targeted plasmin inhibitor: abstract
W. H. van der Laan, H. Ronday, J. Grimbergen, L. Huisman +5 more
20007 citations
Semantic Scholar
79 Inhibition of neointima formation in cultured human saphenous vein segments by an adenovirus expressing an urokinase receptor binding plasmin inhibitor
P. Quax, M. Lamfers, J. Grimbergen, J. Verheijen +1 more
19977 citations
Semantic Scholar
The inactivation of single-chain urokinase-type plasminogen activator by thrombin on cultured human endothelial cells.
E. Braat, A. Collen, An-Nie F. H. Jie, J. Grimbergen +1 more
2000Biochimica et Biophysica Acta2 citations Open access
Semantic Scholar
Effects of infection with recombinant adenovirus on human vascular endothelial and smooth muscle cells
P. Quax, M. Lamfers, J. Grimbergen, J. Teeling +3 more
19962 citations
Semantic Scholar

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P. Quax — researcher profile on SciRah
V. van Hinsbergh×15
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M. D. de Vries×11
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