Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

F. Lupu · SciRah

Researcher profile · Semantic Scholar

F. Lupu

Share profile

F. Lupu — researcher profile on SciRah

h-index: 65
Works: 204
Citations: 18K

Most-cited papers

Inflammation, innate immunity and blood coagulation
Jia-Qiong Xu, F. Lupu, C. Esmon
2010Hämostaseologie204 citations
Semantic Scholar
Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria.
A. Risitano, D. Ricklin, Yijun Huang, E. Reis +13 more
2014Blood194 citations Open access
Semantic Scholar
Complement inhibition decreases the procoagulant response and confers organ protection in a baboon model of Escherichia coli sepsis.
R. Silasi-Mansat, Hua Zhu, N. Popescu, G. Peer +9 more
2010Blood194 citations Open access
Semantic Scholar
New analogs of the clinical complement inhibitor compstatin with subnanomolar affinity and enhanced pharmacokinetic properties
Hongchang Qu, D. Ricklin, Hong-Jun Bai, Hui Chen +8 more
2012Immunobiology154 citations Open access
Semantic Scholar
Crosstalk between the coagulation and complement systems in sepsis
F. Lupu, R. Keshari, John D Lambris, K. Coggeshall
2014Thrombosis Research141 citations Open access
Semantic Scholar
MicroRNA-19 (miR-19) Regulates Tissue Factor Expression in Breast Cancer Cells*
Xiaoxi Zhang, Hai-Jun Yu, Jessica R. Lou, Jie Zheng +5 more
2010Journal of Biological Chemistry140 citations Open access
Semantic Scholar
Endothelial epsin deficiency decreases tumor growth by enhancing VEGF signaling.
Satish Pasula, Xiaofeng Cai, Yun-Zhou Dong, Mirko Messa +21 more
2012Journal of Clinical Investigation115 citations Open access
Semantic Scholar
Extracellular protein disulfide isomerase regulates coagulation on endothelial cells through modulation of phosphatidylserine exposure.
N. Popescu, C. Lupu, F. Lupu
2010Blood115 citations Open access
Semantic Scholar
Disseminated intravascular coagulation and its immune mechanisms
N. Popescu, C. Lupu, F. Lupu
2021Blood110 citations Open access
Semantic Scholar
Inhibition of complement C5 protects against organ failure and reduces mortality in a baboon model of Escherichia coli sepsis
R. Keshari, R. Silasi, N. Popescu, Maulin M. Patel +6 more
2017Proceedings of the National Academy of Sciences of the United States of America107 citations Open access
Semantic Scholar
PDGFRβ signaling regulates local inflammation and synergizes with hypercholesterolemia to promote atherosclerosis
Chao-Yong He, Shayna C Medley, Taishan Hu, Myron E. Hinsdale +3 more
2015Nature Communications107 citations Open access
Semantic Scholar
Activated protein C inhibits neutrophil extracellular trap formation in vitro and activation in vivo
Laura D. Healy, C. Puy, José A. Fernández, Annachiara Mitrugno +8 more
2017Journal of Biological Chemistry99 citations Open access
Semantic Scholar
Pro-fibrotic infrapatellar fat pad remodeling without M1-macrophage polarization precedes knee osteoarthritis in diet-induced obese mice
Erika Barboza, Joanna Hudson, Wan-Pin Chang, S. Kovats +5 more
2017Arthritis & Rheumatology90 citations Open access
Semantic Scholar
Differential regulation of human and murine P-selectin expression and function in vivo
Zhenghui Liu, J. Miner, T. Yago, Longbiao Yao +3 more
2010Journal of Experimental Medicine77 citations Open access
Semantic Scholar
Kupffer cell receptor CLEC4F is important for the destruction of desialylated platelets in mice
Yi-Zhi Jiang, Ya-Qiong Tang, Christopher Hoover, Y. Kondo +16 more
2021Cell Death and Differentiation71 citations Open access
Semantic Scholar
Novel protein ADTRP regulates TFPI expression and function in human endothelial cells in normal conditions and in response to androgen.
C. Lupu, Hua Zhu, N. Popescu, J. Wren +1 more
2011Blood70 citations Open access
Semantic Scholar
Inhibition of contact-mediated activation of factor XI protects baboons against S aureus-induced organ damage and death.
R. Silasi, R. Keshari, C. Lupu, W. J. V. van Rensburg +11 more
2019Blood Advances66 citations Open access
Semantic Scholar
Sphingosine 1‐phosphate and its carrier apolipoprotein M in human sepsis and in Escherichia coli sepsis in baboons
Cecilia Frej, A. Linder, Kaisa E. Happonen, F. Taylor +2 more
2016Journal of Cellular and Molecular Medicine59 citations Open access
Semantic Scholar
Notch3 Arg170Cys Knock-In Mice Display Pathologic and Clinical Features of the Neurovascular Disorder Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy
G. Wallays, D. Nuyens, R. Silasi-Mansat, Joris Souffreau +8 more
2011Arteriosclerosis, Thrombosis and Vascular Biology53 citations
Semantic Scholar
Bacillus anthracis peptidoglycan activates human platelets through FcγRII and complement.
Da-Wei Sun, N. Popescu, B. Raisley, R. Keshari +3 more
2013Blood50 citations Open access
Semantic Scholar
L-SIGN is a receptor on liver sinusoidal endothelial cells for SARS-CoV-2 virus
Y. Kondo, Jason L. Larabee, Liang Gao, Huiping Shi +17 more
2021JCI Insight49 citations Open access
Semantic Scholar
The contact pathway and sepsis
Vikram Raghunathan, J. Zilberman-Rudenko, S. Olson, F. Lupu +2 more
2019Research and Practice in Thrombosis and Haemostasis43 citations Open access
Semantic Scholar
The NuRD Chromatin-Remodeling Enzyme CHD4 Promotes Embryonic Vascular Integrity by Transcriptionally Regulating Extracellular Matrix Proteolysis
Kyle G. Ingram, Carol D. Curtis, R. Silasi-Mansat, F. Lupu +1 more
2013PLoS Genetics41 citations Open access
Semantic Scholar
In vivo detection of free radicals using molecular MRI and immuno-spin trapping in a mouse model for amyotrophic lateral sclerosis.
R. Towner, N. Smith, D. Saunders, F. Lupu +8 more
2013Free Radical Biology & Medicine39 citations
Semantic Scholar
Complement inhibition decreases early fibrogenic events in the lung of septic baboons
R. Silasi-Mansat, Hua Zhu, C. Georgescu, N. Popescu +8 more
2015Journal of Cellular and Molecular Medicine38 citations Open access
Semantic Scholar
Early Antibiotic Exposure Alters Intestinal Development and Increases Susceptibility to Necrotizing Enterocolitis: A Mechanistic Study
Hala Chaaban, Maulin M. Patel, Kathryn Y. Burge, Jeffrey V. Eckert +8 more
2022Microorganisms37 citations Open access
Semantic Scholar
Elevated CXCL1 expression in gp130-deficient endothelial cells impairs neutrophil migration in mice.
Longbiao Yao, T. Yago, Bo-Jing Shao, Zhenghui Liu +4 more
2013Blood37 citations Open access
Semantic Scholar
Acute lung injury and fibrosis in a baboon model of Escherichia coli sepsis.
R. Keshari, R. Silasi-Mansat, Hua Zhu, N. Popescu +7 more
2013American Journal of Respiratory Cell and Molecular Biology37 citations Open access
Semantic Scholar
The sepsis model: An emerging hypothesis for the lethality of inhalation anthrax
K. Coggeshall, F. Lupu, J. Ballard, J. Metcalf +3 more
2013Journal of Cellular and Molecular Medicine37 citations Open access
Semantic Scholar
In Vivo Imaging of Immuno-Spin Trapped Radicals With Molecular Magnetic Resonance Imaging in a Diabetic Mouse Model
R. Towner, N. Smith, D. Saunders, Michael D. Henderson +8 more
2012Diabetes37 citations Open access
Semantic Scholar
Peptidoglycan induces disseminated intravascular coagulation in baboons through activation of both coagulation pathways.
N. Popescu, R. Silasi, R. Keshari, Alanson Girton +6 more
2018Blood35 citations Open access
Semantic Scholar
DNA and factor VII-activating protease protect against the cytotoxicity of histones.
G. Marsman, H. V. von Richthofen, I. Bulder, F. Lupu +3 more
2017Blood Advances34 citations Open access
Semantic Scholar
In vivo-generated thrombin and plasmin do not activate the complement system in baboons.
R. Keshari, R. Silasi, C. Lupu, F. Taylor +1 more
2017Blood31 citations Open access
Semantic Scholar
Suppression of Tumor Growth in Mice by Rationally Designed Pseudopeptide Inhibitors of Fibroblast Activation Protein and Prolyl Oligopeptidase
K. Jackson, V. J. Christiansen, V. Yadav, R. Silasi-Mansat +4 more
2015Neoplasia31 citations Open access
Semantic Scholar
In vivo detection of free radicals in mouse septic encephalopathy using molecular MRI and immuno-spin trapping.
R. Towner, P. Garteiser, F. Bozza, N. Smith +11 more
2013Free Radical Biology & Medicine31 citations Open access
Semantic Scholar
Pathophysiology, staging and therapy of severe sepsis in baboon models
F. Taylor, G. Kinasewitz, F. Lupu
2012Journal of Cellular and Molecular Medicine31 citations Open access
Semantic Scholar
In vivo detection of inducible nitric oxide synthase in rodent gliomas.
R. Towner, N. Smith, S. Doblas, P. Garteiser +6 more
2010Free Radical Biology & Medicine30 citations
Semantic Scholar
Endothelial plasminogen activator inhibitor-1 blocks the intrinsic pathway of coagulation, inducing the clearance and degradation of factor XIa.
C. Puy, A. Ngo, J. Pang, R. Keshari +6 more
2019Arteriosclerosis, Thrombosis and Vascular Biology26 citations Open access
Semantic Scholar
Motif mimetic of epsin perturbs tumor growth and metastasis.
Yun-Zhou Dong, Hao Wu, H. N. Rahman, Yanjun Liu +23 more
2015Journal of Clinical Investigation26 citations Open access
Semantic Scholar
Role of PDI in regulating tissue factor:FVIIa activity
N. Popescu, C. Lupu, F. Lupu
2010Thrombosis Research26 citations Open access
Semantic Scholar
Plasma Viral miRNAs Indicate a High Prevalence of Occult Viral Infections
Enrique Fuentes-Mattei, D. Giza, M. Shimizu, C. Ivan +15 more
2017EBioMedicine25 citations Open access
Semantic Scholar
Bacillus anthracis Lethal Toxin Reduces Human Alveolar Epithelial Barrier Function
Marybeth Langer, E. Duggan, J. Booth, V. I. Patel +14 more
2012Infection and Immunity25 citations Open access
Semantic Scholar
Anti–miR-93-5p therapy prolongs sepsis survival by restoring the peripheral immune response
M. Dragomir, Enrique Fuentes-Mattei, M. Winkle, K. Okubo +35 more
2023Journal of Clinical Investigation22 citations Open access
Semantic Scholar
Molecular MRI assessment of vascular endothelial growth factor receptor-2 in rat C6 gliomas
T. He, N. Smith, D. Saunders, S. Doblas +7 more
2010Journal of Cellular and Molecular Medicine22 citations Open access
Semantic Scholar
The NuRD chromatin-remodeling complex enzyme CHD4 prevents hypoxia-induced endothelial Ripk3 transcription and murine embryonic vascular rupture
S. Colijn, Siqi Gao, Kyle G. Ingram, Matthew T. Menendez +6 more
2019Cell Death and Differentiation21 citations Open access
Semantic Scholar
Targeting ELTD1, an angiogenesis marker for glioblastoma (GBM), also affects VEGFR2: molecular-targeted MRI assessment.
Jadith Ziegler, M. Zalles, N. Smith, D. Saunders +7 more
2019American Journal of Nuclear Medicine and Molecular Imaging21 citations
Semantic Scholar
In Vivo Targeted Molecular Magnetic Resonance Imaging of Free Radicals in Diabetic Cardiomyopathy within Mice
R. Towner, N. Smith, D. Saunders, J. Carrizales +4 more
2015Free radical research21 citations Open access
Semantic Scholar
Insights into the Functional Role of ADTRP (Androgen-Dependent TFPI-Regulating Protein) in Health and Disease
C. Lupu, Maulin M. Patel, F. Lupu
2021International Journal of Molecular Sciences19 citations Open access
Semantic Scholar
Role of ADTRP (Androgen‐Dependent Tissue Factor Pathway Inhibitor Regulating Protein) in Vascular Development and Function
Maulin M. Patel, Amanda R. Behar, R. Silasi, G. Regmi +4 more
2018Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease19 citations Open access
Semantic Scholar
Complement C5 inhibition protects against hemolytic anemia and acute kidney injury in anthrax peptidoglycan-induced sepsis in baboons
R. Keshari, N. Popescu, R. Silasi, G. Regmi +5 more
2021Proceedings of the National Academy of Sciences of the United States of America18 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

R. Silasi-Mansat×19
Invite
R. Silasi-Mansat — researcher profile on SciRah
C. Lupu×14
Invite
C. Lupu — researcher profile on SciRah
R. Keshari×14
Invite
R. Keshari — researcher profile on SciRah
N. Popescu×12
Invite
N. Popescu — researcher profile on SciRah

×10

Invite

R. Towner — researcher profile on SciRah

Invite

D. Saunders — researcher profile on SciRah

Invite

R. Silasi — researcher profile on SciRah

K. Coggeshall×7

Invite

K. Coggeshall — researcher profile on SciRah

Invite

N. Smith — researcher profile on SciRah

John D Lambris×6

Invite

John D Lambris — researcher profile on SciRah

Invite

Hua Zhu — researcher profile on SciRah

Invite

F. Taylor — researcher profile on SciRah