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C. Chiu · SciRah

Researcher profile · Semantic Scholar

C. Chiu

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C. Chiu — researcher profile on SciRah

h-index: 18
Works: 40
Citations: 2,454

Most-cited papers

A Therapeutic Antibody Targeting BACE1 Inhibits Amyloid-β Production in Vivo
J. Atwal, Yongmei Chen, C. Chiu, D. Mortensen +16 more
2011Science Translational Medicine252 citations
Semantic Scholar
Targeting PTPRK-RSPO3 colon tumours promotes differentiation and loss of stem-cell function
E. Storm, S. Durinck, F. de Sousa e Melo, Jarrod R. Tremayne +14 more
2015Nature235 citations
Semantic Scholar
Therapeutic antibodies reveal Notch control of transdifferentiation in the adult lung
D. Lafkas, Amy L. Shelton, C. Chiu, Gladys de Leon Boenig +19 more
2015Nature218 citations
Semantic Scholar
Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analog
C. Chiu, A. G. Watts, L. Lairson, M. Gilbert +4 more
2004Nature Structural &Molecular Biology218 citations
Semantic Scholar
Opposing activities of Notch and Wnt signaling regulate intestinal stem cells and gut homeostasis
H. Tian, B. Biehs, C. Chiu, Christopher W. Siebel +4 more
2015Cell Reports215 citations Open access
Semantic Scholar
High-throughput screening methodology for the directed evolution of glycosyltransferases
A. Aharoni, K. Thieme, C. Chiu, Sabrina Buchini +5 more
2006Nature Methods212 citations
Semantic Scholar
Wnt Isoform-Specific Interactions with Coreceptor Specify Inhibition or Potentiation of Signaling by LRP6 Antibodies
Yan-Zhang Gong, Eric Le Bourhis, C. Chiu, S. Stawicki +12 more
2010PLoS ONE209 citations Open access
Semantic Scholar
Wnt antagonists bind through a short peptide to the first β-propeller domain of LRP5/6.
Eric Le Bourhis, Wei-Ru Wang, C. Tam, Jiyoung Hwang +13 more
2011Structure195 citations Open access
Semantic Scholar
A Therapeutic Antibody Targeting Bace1 Inhibits Amyloid-beta Production in Vivo
J. Atwal, Yongmei Chen, C. Chiu, D. Mortensen +16 more
2013103 citations
Semantic Scholar
Structural analysis of the alpha-2,3-sialyltransferase Cst-I from Campylobacter jejuni in apo and substrate-analogue bound forms.
C. Chiu, L. Lairson, M. Gilbert, W. Wakarchuk +2 more
2007Biochemistry102 citations
Semantic Scholar
Intermediate Trapping on a Mutant Retaining α-Galactosyltransferase Identifies an Unexpected Aspartate Residue*
L. Lairson, C. Chiu, H. Ly, Shou-Ming He +3 more
2004Journal of Biological Chemistry94 citations Open access
Semantic Scholar
Blocking NRG1 and Other Ligand-Mediated Her4 Signaling Enhances the Magnitude and Duration of the Chemotherapeutic Response of Non–Small Cell Lung Cancer
G. Hegde, C. C. de la Cruz, C. Chiu, Navneet Alag +17 more
2013Science Translational Medicine78 citations
Semantic Scholar
Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists
Yingnan Zhang, M. Ultsch, N. Skelton, D. Burdick +12 more
2017Nature Structural &Molecular Biology57 citations
Semantic Scholar
An Anti–CLL-1 Antibody–Drug Conjugate for the Treatment of Acute Myeloid Leukemia
B. Zheng, Shang-Fan Yu, Geoffrey Del Rosario, S. Leong +15 more
2018Clinical Cancer Research53 citations Open access
Semantic Scholar
Apolipoprotein L1-Specific Antibodies Detect Endogenous APOL1 inside the Endoplasmic Reticulum and on the Plasma Membrane of Podocytes.
S. Scales, Nidhi Gupta, A. De Mazière, G. Posthuma +10 more
2020Journal of the American Society of Nephrology45 citations Open access
Semantic Scholar
Structure and Mechanism of the Lipooligosaccharide Sialyltransferase from Neisseria meningitidis*
L. Lin, Bojana Rakić, C. Chiu, Emilie Lameignère +3 more
2011Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Dual antibody inhibition of KLK5 and KLK7 for Netherton syndrome and atopic dermatitis
Joseph Chavarria-Smith, C. Chiu, J. Jackman, Jianping Yin +29 more
2022Science Translational Medicine42 citations Open access
Semantic Scholar
Rapid identification of anti-idiotypic mAbs with high affinity and diverse epitopes by rabbit single B-cell sorting-culture and cloning technology
Wei-Yu Lin, Wei-Ching Liang, Trung Nguy, M. Maia +5 more
2020PLoS ONE23 citations Open access
Semantic Scholar
A phase 1 study to evaluate the safety and LDL cholesterol–lowering effects of RG7652, a fully human monoclonal antibody against proprotein convertase subtilisin/kexin type 9
A. Baruch, D. Luca, Robert Kahn, K. Cowan +8 more
2017Clinical Cardiology18 citations Open access
Semantic Scholar
Genome-wide association study identifies kallikrein 5 in type 2 inflammation-low asthma.
J. Jackman, A. Stockwell, David D. Choy, M. M. Xie +26 more
2022Journal of Allergy and Clinical Immunology12 citations Open access
Semantic Scholar
Novel Anti-LY6G6D/CD3 T-Cell–Dependent Bispecific Antibody for the Treatment of Colorectal Cancer
Pei-Yin Wang, L. Sun, Robyn Clark, Maria Hristopoulos +21 more
2022Molecular Cancer Therapeutics11 citations Open access
Semantic Scholar
Antibody-mediated stabilization of NRG1 induces behavioral and electrophysiological alterations in adult mice
Sara L. Dominguez, G. Hegde, Jesse E. Hanson, Hong Xiang +10 more
2018Scientific Reports10 citations Open access
Semantic Scholar
Thiosemicarbazide complexes of mercury (II) halides
C. Chieh, L. Lee, C. Chiu
19789 citations
Semantic Scholar
Method of treating retinopathy with an anti-LRP5 antibody
Yan Wu, Wei-Lan Ye, J. Burton, C. Chiu
20161 citations
Semantic Scholar
Anti-cll-1 and immunoconjugates
Wei-Ching Liang, Yan Wu, A. Polson, B. Zheng +1 more
20170 citations
Semantic Scholar
O1‐06‐02: Enhancing antibody uptake in brain to target BACE1
Jasi Atwal, Joyleene T. Yu, Yin Zhang, Yongmei Chen +9 more
20120 citations
Semantic Scholar
Structure of Neisseria LOS-specific sialyltransferase (NST), in complex with CDP.
L. Y. Lin, Bojana Rakić, C. Chiu, Emilie Lameignère +3 more
20110 citations
Semantic Scholar
Atwal in Vivo Production β A Therapeutic Antibody Targeting BACE 1 Inhibits Amyloid -
J. Atwal, Yongmei Chen, C. Chiu, D. Mortensen +16 more
20110 citations
Semantic Scholar
Methods and compositions for immunotherapy of neuronal diseases
J. Atwal, Yongmei Chen, C. Chiu, R. Lazarus +4 more
20110 citations
Semantic Scholar
Structure of Neisseria LOS-specific sialyltransferase (NST).
L. Y. Lin, Bojana Rakić, C. Chiu, Emilie Lameignère +3 more
20110 citations
Semantic Scholar
Structure of Neisseria LOS-specific sialyltransferase (NST), in complex with CMP-3F-Neu5Ac.
L. Y. Lin, Bojana Rakić, C. Chiu, Emilie Lameignère +3 more
20110 citations
Semantic Scholar
Structure Basis of Allosteric Inhibition of BACE1 by an Exosite-Binding Antibody
W. Wang, L. Rougé, P. Wu, C. Chiu +3 more
20110 citations
Semantic Scholar
Crystallographic studies of bacterial sialyltransferases
C. Chiu
20070 citations
Semantic Scholar
Crystal structure of alpha-2,3-sialyltransferase from Campylobacter jejuni in apo form
C. Chiu, L. Lairson, M. Gilbert, W. Wakarchuk +2 more
20070 citations
Semantic Scholar
Xray structure of alpha-2,3/8-sialyltransferase CstII F91Y mutant
C. Chiu, N. Strynadka
20070 citations
Semantic Scholar
Crystal structure analysis of monofunctional alpha-2,3-sialyltransferase Cst-I from Campylobacter jejuni
C. Chiu, L. Lairson, M. Gilbert, W. Wakarchuk +2 more
20070 citations
Semantic Scholar
Host Receptors of Bacterial Origin
Calvin K. Yip, C. Chiu, N. Strynadka
20050 citations
Semantic Scholar
Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analogue, cytidine-5'-monophosphate
C. Chiu, A. G. Watts, L. Lairson, M. Gilbert +4 more
20040 citations
Semantic Scholar
Crystal Structural Analysis of Active Site Mutant Q189E of LgtC
L. Lairson, C. Chiu, H. Ly, Shou-Ming He +3 more
20040 citations
Semantic Scholar
Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analogue, CMP-3FNeuAc.
C. Chiu, A. G. Watts, L. L. Lairson, M. Gilbert +4 more
20040 citations
Semantic Scholar

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