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Sara L. Dominguez · SciRah

Researcher profile · Semantic Scholar

Sara L. Dominguez

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Sara L. Dominguez — researcher profile on SciRah

h-index: 12
Works: 17
Citations: 1,171

Most-cited papers

Ser1292 Autophosphorylation Is an Indicator of LRRK2 Kinase Activity and Contributes to the Cellular Effects of PD Mutations
Zejuan Sheng, Shuo Zhang, D. Bustos, Tracy Kleinheinz +21 more
2012Science Translational Medicine363 citations
Semantic Scholar
Discovery of highly potent, selective, and brain-penetrable leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors.
Anthony A. Estrada, Xing-Rong Liu, C. Baker-Glenn, A. Beresford +35 more
2012Journal of Medicinal Chemistry151 citations Open access
Semantic Scholar
Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease
Claire E. Le Pichon, William J. Meilandt, Sara L. Dominguez, Hilda Solanoy +25 more
2017Science Translational Medicine134 citations
Semantic Scholar
Discovery of highly potent, selective, and brain-penetrant aminopyrazole leucine-rich repeat kinase 2 (LRRK2) small molecule inhibitors.
Anthony A. Estrada, Bryan K. Chan, C. Baker-Glenn, A. Beresford +28 more
2014Journal of Medicinal Chemistry113 citations Open access
Semantic Scholar
Interfering with the Chronic Immune Response Rescues Chronic Degeneration After Traumatic Brain Injury
A. Ertürk, Susanne Mentz, E. E. Stout, M. Hedehus +9 more
2016Journal of Neuroscience84 citations Open access
Semantic Scholar
Cognitive Deficits, Changes in Synaptic Function, and Brain Pathology in a Mouse Model of Normal Aging
Martin Weber, Tiffany Wu, Jesse E. Hanson, N. Alam +11 more
2015eNeuro70 citations Open access
Semantic Scholar
EGFR Inhibitor Erlotinib Delays Disease Progression but Does Not Extend Survival in the SOD1 Mouse Model of ALS
Claire E. Le Pichon, Sara L. Dominguez, Hilda Solanoy, Hai Ngu +5 more
2013PLoS ONE46 citations Open access
Semantic Scholar
Global proteomics of Ubqln2-based murine models of ALS
A. M. Whiteley, Miguel A. Prado, S. D. de Poot, João A. Paulo +12 more
2020bioRxiv42 citations Open access
Semantic Scholar
Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS.
Arundhati Sengupta-Ghosh, Sara L. Dominguez, Luke Xie, K. Barck +17 more
2019Neurobiology of Disease41 citations Open access
Semantic Scholar
Discovery of a Highly Selective, Brain-Penetrant Aminopyrazole LRRK2 Inhibitor.
Bryan K. Chan, Anthony A. Estrada, Hui-Fen Chen, J. Atherall +20 more
2013ACS Medicinal Chemistry Letters41 citations Open access
Semantic Scholar
Genetic inactivation of RIP1 kinase does not ameliorate disease in a mouse model of ALS
Sara L. Dominguez, E. Varfolomeev, R. Brendza, K. Stark +9 more
2020Cell Death and Differentiation32 citations Open access
Semantic Scholar
Lipid nanoparticle delivery limits antisense oligonucleotide activity and cellular distribution in the brain after intracerebroventricular injection
A. E. Byrnes, Sara L. Dominguez, Chun-Wan Yen, B. I. Laufer +16 more
2023Molecular Therapy: Nucleic Acids28 citations Open access
Semantic Scholar
BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats
Martin Weber, Tiffany Wu, William J. Meilandt, Sara L. Dominguez +14 more
2017Scientific Reports11 citations Open access
Semantic Scholar
Antibody-mediated stabilization of NRG1 induces behavioral and electrophysiological alterations in adult mice
Sara L. Dominguez, G. Hegde, Jesse E. Hanson, Hong Xiang +10 more
2018Scientific Reports10 citations Open access
Semantic Scholar
Inducible EphA4 knockout causes motor deficits in young mice and is not protective in the SOD1G93A mouse model of ALS
Sara L. Dominguez, Timothy Earr, M. Dourado, Hai Ngu +2 more
2020Scientific Reports7 citations Open access
Semantic Scholar
Corrigendum to "Muscle specific kinase (MuSK) activation preserves neuromuscular junctions in the diaphragm but is not sufficient to provide a functional benefit in the SOD1G93A mouse model of ALS" Neurobiology of Disease 124 (2019) 340-352.
Arundhati Sengupta-Ghosh, Sara L. Dominguez, Luke Xie, K. Barck +18 more
2019Neurobiology of Disease0 citations Open access
Semantic Scholar
Characterization of Transgenic Mouse Models of Alzheimer ' s Disease by Fully Automated Analysis of Brain MRI
K. Barck, Kim Malesky, Vineela Gandham, M. Hedehus +7 more
20120 citations
Semantic Scholar

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