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G. ten Have · SciRah

Researcher profile · Semantic Scholar

G. ten Have

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G. ten Have — researcher profile on SciRah

h-index: 23
Works: 93
Citations: 1,883

Most-cited papers

Arginine de novo and nitric oxide production in disease states.
Y. Luiking, G. ten Have, R. Wolfe, N. Deutz
2012American Journal of Physiology. Endocrinology and Metabolism242 citations Open access
Semantic Scholar
Ammonia lowering reverses sarcopenia of cirrhosis by restoring skeletal muscle proteostasis
Avinash Kumar, Gangarao Davuluri, Rafaella Nasciemento deSilva, M. P. Engelen +4 more
2017Hepatology223 citations Open access
Semantic Scholar
Metabolic and molecular responses to leucine enriched branched chain amino acid supplementation in the skeletal muscle of alcoholic cirrhosis
C. Tsien, Gangarao Davuluri, Dharmvir Singh, Allawy Allawy +8 more
2015Hepatology211 citations Open access
Semantic Scholar
Pharmacokinetics of proline-rich tripeptides in the pig.
P. C. van der Pijl, A. Kies, G. ten Have, G. Duchateau +1 more
2008Peptides79 citations
Semantic Scholar
Glutamine Synthetase in Muscle Is Required for Glutamine Production during Fasting and Extrahepatic Ammonia Detoxification*
Youji He, T. Hakvoort, S. Köhler, J. Vermeulen +11 more
2010Journal of Biological Chemistry78 citations Open access
Semantic Scholar
Simultaneous measurement of metabolic flux in portally-drained viscera, liver, spleen, kidney and hindquarter in the conscious pig
G. ten Have, M. Bost, J. C. A. W. Suyk-Wierts, A. E. van den Bogaard +1 more
1996Laboratory Animals. Journal of the Laboratory Animal Science Association69 citations Open access
Semantic Scholar
Increased intestinal amino-acid retention from the addition of carbohydrates to a meal.
N. Deutz, G. ten Have, P. Soeters, P. Moughan
1995Clinical Nutrition66 citations
Semantic Scholar
Route of administration (enteral or parenteral) affects the contribution of L-glutamine to de novo L-arginine synthesis in mice: a stable-isotope study.
P. Boelens, G. Melis, P. V. van Leeuwen, G. ten Have +1 more
2006American Journal of Physiology. Endocrinology and Metabolism56 citations
Semantic Scholar
Impact of β-hydroxy-β-methylbutyrate (HMB) on muscle loss and protein metabolism in critically ill patients: A RCT.
M. V. Viana, F. Becce, O. Pantet, S. Schmidt +7 more
2021Clinical Nutrition55 citations Open access
Semantic Scholar
Transorgan fluxes in a porcine model reveal a central role for liver in acylcarnitine metabolism.
M. Schooneman, G. ten Have, N. V. van Vlies, S. Houten +2 more
2015American Journal of Physiology. Endocrinology and Metabolism51 citations Open access
Semantic Scholar
Metabolic flux measurements across portal drained viscera, liver, kidney and hindquarter in mice
M. Hallemeesch, G. ten Have, N. Deutz
2001Laboratory Animals. Journal of the Laboratory Animal Science Association51 citations
Semantic Scholar
Metabolic phenotyping using kinetic measurements in young and older healthy adults
N. Deutz, J. Thaden, G. ten Have, D. Walker +1 more
2017Metabolism: Clinical and Experimental50 citations Open access
Semantic Scholar
Absorption kinetics of amino acids, peptides, and intact proteins.
G. ten Have, M. Engelen, Y. Luiking, N. Deutz
2007International Journal of Sport Nutrition & Exercise Metabolism48 citations
Semantic Scholar
Interorgan ammonia, glutamate, and glutamine trafficking in pigs with acute liver failure.
L. Ytrebø, S. Sen, C. Rose, G. ten Have +8 more
2006American Journal of Physiology - Gastrointestinal and Liver Physiology45 citations
Semantic Scholar
Enhanced Lacto-Tri-Peptide Bio-Availability by Co-Ingestion of Macronutrients
G. ten Have, P. C. van der Pijl, A. Kies, N. Deutz
2015PLoS ONE35 citations Open access
Semantic Scholar
The bile duct ligated rat: A relevant model to study muscle mass loss in cirrhosis
Cristina R. Bosoi, Mariana M. Oliveira, R. Ochoa-Sanchez, M. Tremblay +4 more
2016Metabolic brain disease34 citations
Semantic Scholar
Systemic and regional haemodynamics in pigs with acute liver failure and the effect of albumin dialysis
L. Ytrebø, S. Sen, C. Rose, N. Davies +8 more
2006Scandinavian Journal of Gastroenterology32 citations Open access
Semantic Scholar
Comprehensive metabolic amino acid flux analysis in critically ill patients
N. Deutz, P. Singer, R. Wierzchowska-McNew, M. V. Viana +6 more
2021Clinical Nutrition31 citations Open access
Semantic Scholar
Nitrogen recycling buffers against ammonia toxicity from skeletal muscle breakdown in hibernating arctic ground squirrels
S. Rice, G. ten Have, J. Reisz, S. Gehrke +7 more
2020Nature Metabolism28 citations Open access
Semantic Scholar
Transhepatic bile acid kinetics in pigs and humans.
H. Eggink, F. S. van Nierop, Marieke G. Schooneman, A. Boelen +8 more
2017Clinical Nutrition28 citations Open access
Semantic Scholar
Time course of nitric oxide production after endotoxin challenge in mice.
V. B. Bráulio, G. ten Have, Yvonne L. J. Vissers, N. Deutz
2004American Journal of Physiology. Endocrinology and Metabolism26 citations
Semantic Scholar
Nitric oxide and L-arginine metabolism in a devascularized porcine model of acute liver failure.
Vikram Sharma, G. ten Have, L. Ytrebø, S. Sen +9 more
2012American Journal of Physiology - Gastrointestinal and Liver Physiology25 citations Open access
Semantic Scholar
Comprehensive metabolic flux analysis to explain skeletal muscle weakness in COPD
M. Engelen, R. Jonker, J. Thaden, G. ten Have +3 more
2020Clinical Nutrition24 citations Open access
Semantic Scholar
Identification of Metabolic Changes in Ileum, Jejunum, Skeletal Muscle, Liver, and Lung in a Continuous I.V. Pseudomonas aeruginosa Model of Sepsis Using Nontargeted Metabolomics Analysis.
Amro Ilaiwy, G. ten Have, J. Bain, M. Muehlbauer +5 more
2019American Journal of Pathology24 citations Open access
Semantic Scholar
Transorgan Short-Chain Fatty Acid Fluxes in the Fasted and Postprandial State in the Pig.
S. Kirschner, G. ten Have, M. Engelen, N. Deutz
2021American Journal of Physiology. Endocrinology and Metabolism22 citations
Semantic Scholar
Morphological and functional impairment in the gut in a partial body irradiation minipig model of GI-ARS
A. Kaur, G. ten Have, Bernadette Hritzo, Nicolaas E. P. Deutz +2 more
2019International Journal of Radiation Biology20 citations
Semantic Scholar
Application of liquid chromatography-mass spectrometry to measure the concentrations and study the synthesis of short chain fatty acids following stable isotope infusions.
R. Meesters, H. van Eijk, G. ten Have, A. D. de Graaf +3 more
2007Journal of chromatography. B, Analytical technologies in the biomedical and life sciences19 citations
Semantic Scholar
New advances in stable tracer methods to assess whole-body protein and amino acid metabolism.
M. Engelen, G. ten Have, J. Thaden, N. Deutz
2019Current opinion in clinical nutrition and metabolic care16 citations
Semantic Scholar
Phenylalanine isotope pulse method to measure effect of sepsis on protein breakdown and membrane transport in the pig.
G. ten Have, M. Engelen, R. Wolfe, N. Deutz
2017American Journal of Physiology. Endocrinology and Metabolism16 citations Open access
Semantic Scholar
Metabolic flux analysis of Branched-chain amino and keto acids (BCAA, BCKA) and β-Hydroxy β-methylbutyric acid (HMB) across multiple organs in the pig.
G. ten Have, Lisa Jansen, M. Schooneman, M. Engelen +1 more
2021American Journal of Physiology. Endocrinology and Metabolism15 citations
Semantic Scholar
Functional and metabolic effects of omega-3 polyunsaturated fatty acid supplementation and the role of β-hydroxy-β-methylbutyrate addition in chronic obstructive pulmonary disease: A randomized clinical trial.
M. Engelen, S. Simbo, L. Ruebush, J. Thaden +6 more
2024Clinical Nutrition13 citations
Semantic Scholar
Females have a different metabolic response to critical illness, measured by comprehensive amino acid flux analysis.
N. Deutz, P. Singer, R. Wierzchowska-McNew, M. V. Viana +6 more
2023Metabolism: Clinical and Experimental13 citations Open access
Semantic Scholar
Obesity- and Sex-related Metabolism of Arginine and Nitric Oxide in Adults.
R. Wierzchowska-McNew, M. Engelen, J. Thaden, G. ten Have +1 more
2022American Journal of Clinical Nutrition13 citations Open access
Semantic Scholar
Metabolic Consequences of Supplemented Methionine in a Clinical Context.
G. Ligthart-Melis, M. Engelen, S. Simbo, G. ten Have +3 more
2020Journal of NutriLife12 citations Open access
Semantic Scholar
Inhibition of jejunal protein synthesis and breakdown in Pseudomonas aeruginosa-induced sepsis pig model.
G. ten Have, M. Engelen, R. Wolfe, N. Deutz
2019American Journal of Physiology - Gastrointestinal and Liver Physiology12 citations Open access
Semantic Scholar
Absence of post-prandial gut anabolism after intake of a low quality protein meal.
G. ten Have, M. Engelen, P. Soeters, N. Deutz
2012Clinical Nutrition12 citations Open access
Semantic Scholar
Characteristics of a Pseudomonas aeruginosa induced porcine sepsis model for multi-organ metabolic flux measurements
G. ten Have, Renske C I Deutz, M. Engelen, R. Wolfe +1 more
2018Laboratory Animals. Journal of the Laboratory Animal Science Association11 citations
Semantic Scholar
Short-chain fatty acid production in accessible and inaccessible body pools as assessed by novel stable tracer pulse approach is reduced by aging independent of presence of COPD.
S. Kirschner, Parisa Ghane, Jaekwan K. Park, S. Simbo +6 more
2023Metabolism: Clinical and Experimental10 citations
Semantic Scholar
Net release and uptake of xenometabolites across intestinal, hepatic, muscle, and renal tissue beds in healthy conscious pigs.
Kelly E. Mercer, G. ten Have, Lindsay M Pack, R. Lan +3 more
2020American Journal of Physiology - Gastrointestinal and Liver Physiology10 citations Open access
Semantic Scholar
Protein fractional synthesis rates within tissues of high- and low-active mice
Kristina M. Cross, Jorge Z. Granados, G. ten Have, J. Thaden +3 more
2020PLoS ONE9 citations Open access
Semantic Scholar
Muscle protein catabolism and splanchnic arginine consumption drive arginine dysregulation during Pseudomonas Aeruginosa induced early acute sepsis in swine.
S. Rice, G. ten Have, M. Engelen, N. Deutz
2024American Journal of Physiology - Gastrointestinal and Liver Physiology7 citations Open access
Semantic Scholar
Attenuating hyperammonemia preserves protein synthesis and muscle mass via restoration of perturbed metabolic pathways in bile duct-ligated rats
Cristina R. Bosoi, Avinash Kumar, Mariana M. Oliveira, N. Welch +8 more
2025Metabolic brain disease6 citations Open access
Semantic Scholar
Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues
Hany F. Sobhi, Kelly E. Mercer, Renny S. Lan, Laxmi Yeruva +6 more
2024Journal of Lipid Research6 citations Open access
Semantic Scholar
The role of adipose and muscle tissue breakdown on interorgan energy substrate fluxes in a Pseudomonas aeruginosa induced sepsis model in female pigs
R. Morse, G. ten Have, J. Thaden, M. Engelen +3 more
2025Physiological Reports5 citations Open access
Semantic Scholar
Absolute bioavailability of a Hoodia gordonii steroid glycoside from different physicochemical formats in the pig
B. Graf, C. V. van Platerink, G. ten Have, N. Deutz +6 more
20114 citations Open access
Semantic Scholar
In-vivo production of branched-chain amino acids, branched-chain keto acids, and β-hydroxy β-methylbutyric acid
G. ten Have, M. Engelen, N. Deutz
2021Current opinion in clinical nutrition and metabolic care3 citations
Semantic Scholar
The acute changes in intracellular amino acid production during sepsis do not relate to plasma concentrations
N. Deutz, G. ten Have, P. P. Nghiem, M. Mackey +4 more
2025Clinical Nutrition2 citations Open access
Semantic Scholar
Prolonged disturbances in citrulline metabolism following resistance exercise in COPD
Tarun Sontam, N. Deutz, C. Cruthirds, Robert H Mbilinyi +4 more
2025Clinical Nutrition2 citations Open access
Semantic Scholar
Non-essential Amino Acids Are Needed to Attenuate ICU Acquired Muscle Weakness (ICU-AW) in a Pig Model of Sepsis Recovery
N. Deutz, G. ten Have, P. P. Nghiem, M. Mackey +2 more
2024Current Developments in Nutrition2 citations Open access
Semantic Scholar
Altered Glutamate and Glutamine Kinetics in Autism Spectrum Disorder
Sofie De Wandel, M. Engelen, R. Wierzchowska-McNew, Julie Thompson +5 more
2021Current Developments in Nutrition2 citations Open access
Semantic Scholar

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