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A. Boelen · SciRah

Researcher profile · Semantic Scholar

A. Boelen

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A. Boelen — researcher profile on SciRah

h-index: 49
Works: 285
Citations: 7,848

Most-cited papers

The interplay of thyroid hormones and the immune system – where we stand and why we need to know about it
Christina Wenzek, A. Boelen, A. Westendorf, D. Engel +2 more
2022European Journal of Endocrinology83 citations Open access
Semantic Scholar
A Comprehensive Review of Thyroid Hormone Metabolism in the Gut and Its Clinical Implications
Aline C. Fenneman, E. Bruinstroop, Max Nieuwdorp, A. H. van der Spek +1 more
2022Thyroid67 citations Open access
Semantic Scholar
Hypothyroidism: The difficulty in attributing symptoms to their underlying cause
H. Jansen, A. Boelen, A. Heijboer, E. Bruinstroop +1 more
2023Frontiers in Endocrinology61 citations Open access
Semantic Scholar
Diagnosis and Management of Central Congenital Hypothyroidism
Peter Lauffer, N. Zwaveling-Soonawala, J. C. Naafs, A. Boelen +1 more
2021Frontiers in Endocrinology52 citations Open access
Semantic Scholar
Sex‐specific newborn screening for X‐linked adrenoleukodystrophy
M. Albersen, S. L. van der Beek, Inge M. E. Dijkstra, M. Alders +17 more
2022Journal of Inherited Metabolic Disease32 citations Open access
Semantic Scholar
Role of hepatic deiodinases in thyroid hormone homeostasis and liver metabolism, inflammation, and fibrosis
E. Bruinstroop, A. H. van der Spek, A. Boelen
2023European Thyroid Journal27 citations Open access
Semantic Scholar
Neonatal screening for primary and central congenital hypothyroidism: is it time to go Dutch?
A. Boelen, N. Zwaveling-Soonawala, A. Heijboer, A. V. van Trotsenburg
2023European Thyroid Journal25 citations Open access
Semantic Scholar
Developmental thyroid disruption permanently affects the neuroglial output in the murine subventricular zone
Pieter Vancamp, K. Le Blay, L. Butruille, A. Sébillot +3 more
2022Stem Cell Reports23 citations Open access
Semantic Scholar
Biomarkers indicating tissue thyroid hormone status: ready to be implemented yet?
H. Jansen, E. Bruinstroop, A. Heijboer, A. Boelen
2022Journal of Endocrinology23 citations Open access
Semantic Scholar
Pregnancy disrupts the accuracy of automated fT4 immunoassays
H. Jansen, A. V. van Herwaarden, H. Huijgen, R. Painter +3 more
2022European Thyroid Journal23 citations Open access
Semantic Scholar
Transient developmental exposure to low doses of bisphenol F negatively affects neurogliogenesis and olfactory behaviour in adult mice.
Pieter Vancamp, L. Butruille, A. Herranen, A. Boelen +3 more
2023Environment International21 citations Open access
Semantic Scholar
[Age-specific reference intervals for thyroid-stimulating hormone and free thyroxine to optimize diagnosis of thyroid disease].
W. D. den Elzen, H. Jansen, N. F. Dirks, J. Hillebrand +5 more
2025Nederlandsch tijdschrift voor geneeskunde17 citations
Semantic Scholar
Age-Specific Reference Intervals for Thyroid-Stimulating Hormones and Free Thyroxine to Optimize Diagnosis of Thyroid Disease
H. Jansen, N. F. Dirks, J. Hillebrand, E. ten Boekel +19 more
2024Thyroid13 citations Open access
Semantic Scholar
Should we depend on reference intervals from manufacturer package inserts? Comparing TSH and FT4 reference intervals from four manufacturers with results from modern indirect methods and the direct method
N. F. Dirks, W. D. den Elzen, J. Hillebrand, H. Jansen +17 more
2024Clinical Chemistry and Laboratory Medicine13 citations Open access
Semantic Scholar
The role of WD40 repeat-containing proteins in endocrine (dys)function.
Yalan Hu, E. Bruinstroop, A. Hollenberg, E. Fliers +1 more
2023Journal of Molecular Endocrinology12 citations Open access
Semantic Scholar
Maleic acid is a biomarker for maleylacetoacetate isomerase deficiency; implications for newborn screening of tyrosinemia type 1
K. van Vliet, A. Dijkstra, M. Bouva, J. van der Krogt +13 more
2023Journal of Inherited Metabolic Disease12 citations Open access
Semantic Scholar
Optimizing the Dutch newborn screening for congenital hypothyroidism by incorporating amino acids and acylcarnitines in a machine learning-based model
H. Jansen, Marije van Haeringen, M. Bouva, W. D. den Elzen +9 more
2023European Thyroid Journal12 citations Open access
Semantic Scholar
Triac Treatment Prevents Neurodevelopmental and Locomotor Impairments in Thyroid Hormone Transporter Mct8/Oatp1c1 Deficient Mice
Jie-Si Chen, Eva Salveridou, L. Liebmann, S. Sundaram +7 more
2022bioRxiv11 citations Open access
Semantic Scholar
A systematic review of subclinical hyperthyroidism guidelines: a remarkable range of recommendations
Stan R. Ursem, A. Boelen, E. Bruinstroop, P. Elders +4 more
2024European Thyroid Journal10 citations Open access
Semantic Scholar
Machine learning to improve false-positive results in the Dutch newborn screening for congenital hypothyroidism.
Kevin Stroek, Allerdien Visser, C. V. D. van der Ploeg, N. Zwaveling-Soonawala +6 more
2023Clinical Biochemistry10 citations Open access
Semantic Scholar
Lower accuracy of testosterone, cortisol, and free T4 measurements using automated immunoassays in people undergoing hemodialysis
H. Jansen, A. V. van Herwaarden, H. Huijgen, M. Vervloet +3 more
2023Clinical Chemistry and Laboratory Medicine10 citations Open access
Semantic Scholar
Insights into the stability of serum calcitonin and a comparison of three serum calcitonin immunoassays.
Amber Mater, A. Boelen, A. Heijboer, J. Hillebrand
2025Clinica chimica acta; international journal of clinical chemistry9 citations Open access
Semantic Scholar
Increased fT4 concentrations in patients using levothyroxine without complete suppression of TSH
H. Jansen, Marijn M Bult, P. Bisschop, A. Boelen +2 more
2023Endocrine Connections9 citations Open access
Semantic Scholar
An animal model for Pierpont syndrome: a mouse bearing the Tbl1xr1Y446C/Y446C mutation
Yalan Hu, Peter Lauffer, Michelle E. Stewart, G. Codner +9 more
2022Human Molecular Genetics9 citations Open access
Semantic Scholar
Newborn screening for central congenital hypothyroidism: past, present and future
M. Garrelfs, C. Mooij, A. Boelen, A. V. van Trotsenburg +1 more
2025European Thyroid Journal8 citations Open access
Semantic Scholar
Stability of steroid hormones in dried blood spots (DBS)
Anouk M. Olthof, J. Hillebrand, Wjera V Wickenhagen, A. Boelen +1 more
2024Clinical Chemistry and Laboratory Medicine8 citations Open access
Semantic Scholar
Neuronal blockade of thyroid hormone signaling increases sensitivity to diet-induced obesity in adult male mice.
Eva Rial Pensado, L. Canaple, R. Guyot, C. Clemmensen +8 more
2023Endocrinology8 citations Open access
Semantic Scholar
Newborn screening and the screening laboratory: past, present and future
A. Boelen, A. Heijboer
2025European Thyroid Journal7 citations Open access
Semantic Scholar
Thyroglobulin and calcitonin measurements: pitfalls and future perspectives.
Amber Mater, A. Boelen, A. Heijboer, J. Hillebrand
2024Journal of Endocrinology7 citations Open access
Semantic Scholar
Neonatal reference intervals for serum steroid hormone concentrations measured by LC-MS/MS
Anouk M. Olthof, J. C. Naafs, N. Zwaveling-Soonawala, C. Heinen +5 more
2024Clinical Chemistry and Laboratory Medicine7 citations Open access
Semantic Scholar
Divergent Thyroid Hormone Levels in Plasma and Left Ventricle of the Heart in Compensated and Decompensated Cardiac Hypertrophy Induced by Chronic Adrenergic Stimulation in Mice
W. Simonides, Alice Tijsma, A. Boelen, R. Jongejan +5 more
2023Metabolites7 citations Open access
Semantic Scholar
Inactivation of Thyroid Hormone Transporters Mct8/Oatp1c1 in Mouse Brain Endothelial Cells Causes Region-Specific Alterations in Central Thyroid Hormone Signaling
Androniki Alevyzaki, Boyka Markova, M. De Angelis, T. Müller +7 more
2025Thyroid6 citations Open access
Semantic Scholar
The Value of Reducing Inconclusive and False-Positive Newborn Screening Results for Congenital Hypothyroidism, Congenital Adrenal Hyperplasia and Maple Syrup Urine Disease in The Netherlands
Rosalie C Martens, A. Boelen, Michèle H. van der Kemp, Annet M. Bosch +8 more
2024International Journal of Neonatal Screening6 citations Open access
Semantic Scholar
Cerebrospinal fluid sex steroid hormones in bacterial meningitis
S. Dias, M. Brouwer, A. Boelen, D. van de Beek
2022Medicine6 citations Open access
Semantic Scholar
Evaluation of Neonatal Screening Programs for Tyrosinemia Type 1 Worldwide
Allysa M Kuypers, M. Bouva, J. G. Loeber, A. Boelen +5 more
2024International Journal of Neonatal Screening5 citations Open access
Semantic Scholar
Steroid hormone concentrations in dried blood spots: A comparison between capillary and venous blood samples.
Anouk M. Olthof, Vera H. de Kleijne, A. Boelen, A. Heijboer
2024Clinica chimica acta; international journal of clinical chemistry5 citations Open access
Semantic Scholar
The need for the GREAT+ score to predict relapse in Graves’ disease: a questionnaire among patients and internal medicine specialists
H. Jansen, C. van Beek, P. Bisschop, A. Heijboer +2 more
2024Journal of Endocrinological Investigation4 citations Open access
Semantic Scholar
Stability of TSH receptor antibody concentrations and comparability of its immunoassays.
H. Jansen, Héloïse G. Gohy, A. Boelen, P. Bisschop +2 more
2023Clinica chimica acta; international journal of clinical chemistry4 citations Open access
Semantic Scholar
The role of transducin β-like 1 X-linked receptor 1 (TBL1XR1) in thyroid hormone metabolism and action in mice
Yalan Hu, Kim Falize, A. V. van Trotsenburg, R. Hennekam +3 more
2023European Thyroid Journal4 citations Open access
Semantic Scholar
Meta-Analysis of DNA Methylation Datasets Shows Aberrant DNA Methylation of Thyroid Development or Function Genes in Down Syndrome
Peter Lauffer, N. Zwaveling-Soonawala, Shaobo Li, M. Bacalini +6 more
2022Thyroid4 citations
Semantic Scholar
Thyroid hormone receptor α signaling shapes innate and adaptive immune responses during viral infection
Christina Wenzek, T. Knuschke, G. S. Hönes, A. Boelen +6 more
2025European Thyroid Journal3 citations Open access
Semantic Scholar
Evaluation of the Performance of Newborn Screening for Tyrosinemia Type 1 in The Netherlands: Suggestions for Improvements Using Additional Biomarkers in Addition to Succinylacetone
M. Bouva, Allysa M Kuypers, E. A. Kemper, Rose E. Maase +6 more
2025International Journal of Neonatal Screening3 citations Open access
Semantic Scholar
Analysis of Serum Free Thyroxine Concentrations in Healthy Term Neonates Underlines Need for Local and Laboratory-Specific Reference Interval: A Systematic Review and Meta-Analysis of Individual Participant Data
Peter Lauffer, C. Heinen, A. Goorsenberg, A. Malekzadeh +5 more
2024Thyroid3 citations Open access
Semantic Scholar
How low can we (reliably) go? A method comparison of thyroid-stimulating hormone assays with a focus on low concentrations
Stan R. Ursem, A. Boelen, J. Hillebrand, W. D. den Elzen +1 more
2023European Thyroid Journal3 citations Open access
Semantic Scholar
Further Delineation of Central Congenital Hypothyroidism due to Variants in TBL1X and IRS4
Peter Lauffer, J. C. Naafs, H. Bikker, M. Garrelfs +4 more
2023Thyroid3 citations Open access
Semantic Scholar
Aging and Western Diet Synergistically Impair Hepatic Thyroid Hormone Signaling to Promote Metabolic Dysfunction‐Associated Steatotic Liver Disease (MASLD) in Mice
Xin-Ru Zhang, M. Tripathi, Chun-Ting Goh, Chee-Seng Chan +4 more
2026Aging Cell2 citations Open access
Semantic Scholar
Evaluation of Newborn Screening for Diseases Using C5‐OH as a Marker: Systematic Review of the Literature and Evaluation of 17 Years of C5‐OH Screening in the Netherlands
Ryan Aukes, Monique Albersen, A. Boelen, L. Kluijtmans +3 more
2025Journal of Inherited Metabolic Disease2 citations Open access
Semantic Scholar
Cost–Effectiveness of Newborn Screening for X-Linked Adrenoleukodystrophy in the Netherlands: A Health-Economic Modelling Study
Rosalie C Martens, H. M. Broulíková, Marc Engelen, S. Kemp +4 more
2025International Journal of Neonatal Screening2 citations Open access
Semantic Scholar
Natural course of subclinical hyperthyroidism in primary care in the Netherlands
Stan R. Ursem, W. D. den Elzen, J. M. van den Berg, A. Boelen +3 more
2025European Thyroid Journal2 citations Open access
Semantic Scholar
21-deoxycortisol as a second-tier test in congenital adrenal hyperplasia newborn screening in The Netherlands: two-year evaluation
Anouk M. Olthof, M. Bouva, Hedi L. Claahsen-van der Grinten, D. Westra +4 more
2025Archives of Disease in Childhood2 citations Open access
Semantic Scholar

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