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S. Dasarathy · SciRah

Researcher profile · Semantic Scholar

S. Dasarathy

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S. Dasarathy — researcher profile on SciRah

h-index: 74
Works: 353
Citations: 27K

Most-cited papers

Estimated Burden of Metabolic Dysfunction–Associated Steatotic Liver Disease in US Adults, 2020 to 2050
Phuc Le, Moosa Tatar, S. Dasarathy, N. Alkhouri +7 more
2025JAMA Network Open226 citations Open access
Semantic Scholar
Fibrosis Progression Rate in Biopsy-proven Nonalcoholic Fatty Liver Disease among People with Diabetes versus People without Diabetes: A Multicenter Study
Daniel Q. Huang, L. Wilson, C. Behling, D. Kleiner +10 more
2023Gastroenterology176 citations Open access
Semantic Scholar
Challenges in and Opportunities for Electronic Health Record-Based Data Analysis and Interpretation
M. Kim, C. Rouphael, J. McMichael, N. Welch +1 more
2023Gut and Liver107 citations Open access
Semantic Scholar
Increases and decreases in liver stiffness measurements are independently associated with the risk of liver-related events in NAFLD
S. Gawrieh, E. Vilar-Gomez, Laura A. Wilson, Francis Pike +10 more
2024Journal of Hepatology77 citations Open access
Semantic Scholar
ACG Clinical Guideline: MALNUTRITION AND NUTRITIONAL RECOMMENDATIONS IN LIVER DISEASE
A. Singal, Robert J. Wong, S. Dasarathy, M. Abdelmalek +4 more
2025American Journal of Gastroenterology76 citations Open access
Semantic Scholar
Liver transplantation in the patient with physical frailty
P. Tandon, A. Zanetto, S. Piano, J. Heimbach +1 more
2023Journal of Hepatology64 citations Open access
Semantic Scholar
The Beneficial Effects of Lactobacillus GG Therapy on Liver and Drinking Assessments in Patients with Moderate Alcohol-Associated Hepatitis
V. Vatsalya, Wen-Ke Feng, M. Kong, Huirong Hu +8 more
2023American Journal of Gastroenterology57 citations Open access
Semantic Scholar
Designing clinical trials to address alcohol use and alcohol-associated liver disease: an expert panel Consensus Statement
Brian P. Lee, Katie Witkiewitz, J. Mellinger, Frank A. Anania +27 more
2024Nature reviews: Gastroenterology & hepatology55 citations Open access
Semantic Scholar
Randomized-controlled trial of anakinra plus zinc vs. prednisone for severe alcohol-associated hepatitis
S. Gawrieh, S. Dasarathy, Wan-Zhu Tu, P. Kamath +11 more
2024Journal of Hepatology53 citations Open access
Semantic Scholar
Macrophage-derived MLKL in alcohol-associated liver disease: regulation of phagocytosis
Xiao-Qin Wu, Xiu-De Fan, M. McMullen, T. Miyata +13 more
2022Hepatology48 citations Open access
Semantic Scholar
Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice
Robert N. Helsley, T. Miyata, Anagha Kadam, Venkateshwari Varadharajan +32 more
2022bioRxiv42 citations Open access
Semantic Scholar
Long-term liver outcomes after metabolic surgery in compensated cirrhosis due to metabolic dysfunction-associated steatohepatitis
Ali Aminian, Abdullah Aljabri, Sarah Wang, James F. Bena +13 more
2025Nature Medicine35 citations
Semantic Scholar
PNPLA3 rs738409, age, diabetes, sex, and advanced fibrosis jointly contribute to the risk of major adverse liver outcomes in Metabolic-Associated Steatotic Liver Disease
N. Chalasani, E. Vilar-Gomez, R. Loomba, Katherine P. Yates +8 more
2024Hepatology29 citations Open access
Semantic Scholar
Weight gain is an early indicator of injury in ex vivo normothermic limb perfusion (EVNLP)
Abigail Meyers, S. Pandey, V. Kopparthy, P. Sadeghi +7 more
2022Artificial Organs28 citations Open access
Semantic Scholar
The Liver Cirrhosis Network Cohort Study: Cirrhosis Definition, Study Population, and Endpoints
E. Tapper, D. Goldberg, N. Parikh, N. Terrault +18 more
2024American Journal of Gastroenterology26 citations
Semantic Scholar
Prevalence of at-risk NASH and its association with metabolic syndrome in US adults with NAFLD, 2017–2018
Julia Y. Payne, N. Alkhouri, P. Le, M. Rothberg +3 more
2023Hepatology Communications25 citations Open access
Semantic Scholar
Dysregulated cellular redox status during hyperammonemia causes mitochondrial dysfunction and senescence by inhibiting sirtuin‐mediated deacetylation
Saurabh Mishra, N. Welch, M. Karthikeyan, A. Bellar +15 more
2023Aging Cell24 citations Open access
Semantic Scholar
Liver Stiffness Progression in Biopsy-proven Metabolic Dysfunction-associated Steatotic Disease among People with Diabetes versus People without Diabetes: A Prospective Multicenter Study
Daniel Q. Huang, Laura A. Wilson, C. Behling, M. Amangurbanova +10 more
2024Hepatology22 citations Open access
Semantic Scholar
Muscle loss phenotype in COPD is associated with adverse outcomes in the UK Biobank
A. Attaway, Rocio Lopez, N. Welch, A. Bellar +4 more
2024BMC Pulmonary Medicine19 citations Open access
Semantic Scholar
Gene polymorphisms associated with heterogeneity and senescence characteristics of sarcopenia in chronic obstructive pulmonary disease
A. Attaway, A. Bellar, N. Welch, Jinendiran Sekar +11 more
2023Journal of Cachexia, Sarcopenia and Muscle19 citations Open access
Semantic Scholar
Value-Based Pricing of Resmetirom for Metabolic Dysfunction–Associated Steatotic Liver Disease
Phuc Le, S. Dasarathy, William H. Herman, O. Adekunle +6 more
2025JAMA Network Open18 citations Open access
Semantic Scholar
New insights into biomarkers and risk stratification to predict hepatocellular cancer
Katrina Li, Brandon Mathew, Ethan Saldanha, Puja Ghosh +5 more
2025Molecular Medicine18 citations Open access
Semantic Scholar
Design of a multicenter randomized clinical trial for treatment of Alcohol-Associated Hepatitis
W. Tu, S. Gawrieh, S. Dasarathy, M. Mitchell +10 more
2023Contemporary Clinical Trials Communications18 citations Open access
Semantic Scholar
Dysregulated meta-organismal metabolism of aromatic amino acids in alcohol-associated liver disease
M. Mrdjen, Emily Huang, Vai S. Pathak, A. Bellar +13 more
2023Hepatology Communications16 citations Open access
Semantic Scholar
Aldehydes alter TGF-β signaling and induce obesity and cancer
Xiao-Chun Yang, Krishanu Bhowmick, Shuyun Rao, Xiyan Xiang +21 more
2024Cell Reports14 citations Open access
Semantic Scholar
The impact of integrated care on clinical outcomes in patients with alcohol-associated liver disease: Early outcomes from a multidisciplinary clinic
Shreya Sengupta, A. Anand, Qi-Jun Yang, Meghan Reagan +6 more
2025Hepatology Communications13 citations
Semantic Scholar
Perspective on alcohol-induced organ damage via autophagy-dependent cellular changes
Ahmed A Bakheet, M. Anbazhagan, Shirish Barve, S. Dasarathy +15 more
2025Redox Biology13 citations Open access
Semantic Scholar
Membrane-bound O-acyltransferase 7 (MBOAT7) shapes lysosomal lipid homeostasis and function to control alcohol-associated liver injury
Venkateshwari Varadharajan, Iyappan Ramachandiran, William J. Massey, Raghav Jain +20 more
2024eLife13 citations Open access
Semantic Scholar
Development and evaluation of objective trial performance metrics for multisite clinical studies: Experience from the AlcHep Network
S. Dasarathy, Wan-Zhu Tu, A. Bellar, N. Welch +6 more
2024Contemporary Clinical Trials13 citations Open access
Semantic Scholar
Sex related differences in muscle health and metabolism in chronic obstructive pulmonary disease.
M. Engelen, S. Kirschner, K. Coyle, D. Argyelan +3 more
2023Clinical Nutrition12 citations Open access
Semantic Scholar
Proteomics identifies complement protein signatures in patients with alcohol-associated hepatitis
Moyinoluwa Taiwo, Emily Huang, Vai S. Pathak, A. Bellar +18 more
2024JCI Insight11 citations Open access
Semantic Scholar
Alcohol-induced extracellular ASC specks perpetuate liver inflammation and damage in alcohol-associated hepatitis even after alcohol cessation
Marcelle de Carvalho Ribeiro, Arvin Iracheta-Vellve, Mrigya Babuta, Charles D. Calenda +16 more
2023Hepatology11 citations
Semantic Scholar
Ammonia transporter RhBG initiates downstream signaling and functional responses by activating NFκB
Saurabh Mishra, N. Welch, Shashi S. Singh, K. D. Singh +16 more
2024Proceedings of the National Academy of Sciences of the United States of America10 citations
Semantic Scholar
Ammonia measurement in cirrhosis: International Delphi consensus recommendations from ISHEN.
M. Ballester, Rocio Gallego-Duran, Shalimar, K. Thomsen +46 more
2026Journal of Hepatology9 citations Open access
Semantic Scholar
L-Isoleucine reverses hyperammonemia-induced myotube mitochondrial dysfunction and post-mitotic senescence
Avinash Kumar, A. Bellar, Saurabh Mishra, Jinendiran Sekar +2 more
2023Journal of Nutritional Biochemistry9 citations Open access
Semantic Scholar
Mincle-GSDMD-mediated release of IL-1β small extracellular vesicles from hepatic macrophages in ethanol-induced liver injury
Quanri Zhang, Weiwei Liu, K. Bulek, Han Wang +8 more
2023Hepatology Communications9 citations Open access
Semantic Scholar
Acute kidney injury in severe alcohol-associated hepatitis treated with anakinra plus zinc or prednisone
Kavish R. Patidar, Wan-Zhu Tu, Thomas G. Cotter, Douglas A. Simonetto +19 more
2024Hepatology8 citations Open access
Semantic Scholar
Insulin increases type I collagen synthesis in hepatic stellate cells via α5β1 integrin
M. Dodig, Min Li, S. Dasarathy, Sivarajan Kumarasamy +3 more
2024Metabolism and Target Organ Damage8 citations Open access
Semantic Scholar
Natural history and development of a novel composite endpoint in patients with alcohol-associated Hepatitis: Data from a prospective multicenter study
S. Dasarathy, Wan-Zhu Tu, N. Welch, Samer Gawreh +12 more
2025Hepatology7 citations
Semantic Scholar
Association of Components of Metabolic Syndrome and the Progression of Nonalcoholic Fatty Liver Disease
Phuc Le, Moosa Tatar, Michael B. Rothberg, Laura A. Wilson +9 more
2025American Journal of Gastroenterology7 citations
Semantic Scholar
Peripheral blood mononuclear cell mitochondrial dysfunction in acute alcohol‐associated hepatitis
A. Bellar, N. Welch, Jaividhya Dasarathy, A. Attaway +8 more
2023Clinical and Translational Medicine7 citations Open access
Semantic Scholar
5S rRNA pseudogene transcripts are associated with interferon production and inflammatory responses in alcohol-associated hepatitis
Jian-Guo Wu, Adam Kim, Xiao-Qin Wu, Semanti Ray +6 more
2023Hepatology7 citations
Semantic Scholar
Attenuating hyperammonemia preserves protein synthesis and muscle mass via restoration of perturbed metabolic pathways in bile duct-ligated rats
Cristina R. Bosoi, Avinash Kumar, Mariana M. Oliveira, N. Welch +8 more
2025Metabolic brain disease6 citations Open access
Semantic Scholar
Integrated Multiomics Analyses of the Molecular Landscape of Sarcopenia in Alcohol‐Related Liver Disease
N. Welch, Pugazhendhi Kannan, Saurabh Mishra, A. Bellar +11 more
2025Journal of Cachexia, Sarcopenia and Muscle6 citations Open access
Semantic Scholar
Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in patients with cirrhosis
Xiyan Xiang, Krishanu Bhowmick, K. Shetty, Kazufumi Ohshiro +18 more
2024Genes & cancer6 citations Open access
Semantic Scholar
Association between pattern of hepatic iron deposition and severity of MASH among patients enrolled in the NASH Clinical Research Network
Aalam Sohal, Laura A. Wilson, David E. Kleiner, R. Loomba +7 more
2025Hepatology Communications5 citations
Semantic Scholar
Microbial metabolite ammonia disrupts TGF-β signaling to promote colon cancer
Krishanu Bhowmick, Xiao-Chun Yang, Taj Mohammad, Xiyan Xiang +7 more
2025Journal of Biological Chemistry5 citations
Semantic Scholar
Differential impact of sex on regulation of skeletal muscle mitochondrial function and protein homeostasis by hypoxia-inducible factor-1α in normoxia
N. Welch, Saurabh Mishra, A. Bellar, Pugazhendhi Kannan +12 more
2024Journal of Physiology5 citations
Semantic Scholar
Using the Electronic Health Record to Develop a Gastric Cancer Risk Prediction Model
M. Kim, C. Rouphael, S. Wehbe, Ji Yoon Yoon +5 more
2024Gastro Hep Advances4 citations Open access
Semantic Scholar
The pyruvate dehydrogenase kinase inhibitor dichloroacetate mitigates alcohol-induced hepatic inflammation and metabolic disturbances in mice
Jianguo Wu, Emily Huang, Megan R. McMullen, Vaibhav Singh +9 more
2024Hepatology Communications4 citations Open access
Semantic Scholar

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