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P. Sorgen · SciRah

Researcher profile · Semantic Scholar

P. Sorgen

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P. Sorgen — researcher profile on SciRah

h-index: 34
Works: 105
Citations: 3,499

Most-cited papers

Structural Changes in the Carboxyl Terminus of the Gap Junction Protein Connexin43 Indicates Signaling between Binding Domains for c-Src and Zonula Occludens-1*
P. Sorgen, H. Duffy, P. Sahoo, W. Coombs +2 more
2004Journal of Biological Chemistry191 citations Open access
Semantic Scholar
pH-Dependent Intramolecular Binding and Structure Involving Cx43 Cytoplasmic Domains*
H. Duffy, P. Sorgen, M. Girvin, Phyllis M. O'Donnell +4 more
2002Journal of Biological Chemistry185 citations Open access
Semantic Scholar
Phosphorylation at S365 is a gatekeeper event that changes the structure of Cx43 and prevents down-regulation by PKC
J. Solan, Lucrecia Márquez‐Rosado, P. Sorgen, P. Thornton +2 more
2007Journal of Cell Biology183 citations Open access
Semantic Scholar
An evaluation of detergents for NMR structural studies of membrane proteins
Ray D. Krueger-Koplin, P. Sorgen, S. Krueger-Koplin, Iván O. Rivera-Torres +5 more
2004Journal of Biomolecular NMR176 citations
Semantic Scholar
Structural and Molecular Mechanisms of Gap Junction Remodeling in Epicardial Border Zone Myocytes following Myocardial Infarction
Fabien Kieken, Nancy A. M. Mutsaers, E. Dolmatova, Kelly L. Virgil +5 more
2009Circulation Research143 citations Open access
Semantic Scholar
Endogenous oxidized DNA bases and APE1 regulate the formation of G-quadruplex structures in the genome
Shrabasti Roychoudhury, Suravi Pramanik, Hannah L. Harris, Mason W. Tarpley +7 more
2020Proceedings of the National Academy of Sciences of the United States of America113 citations Open access
Semantic Scholar
Structural bases for the chemical regulation of Connexin43 channels.
M. Delmar, W. Coombs, P. Sorgen, H. Duffy +1 more
2004Cardiovascular Research110 citations
Semantic Scholar
Cardiomyocyte ATP release through pannexin 1 aids in early fibroblast activation.
E. Dolmatova, Gaelle Spagnol, D. Boassa, J. Baum +6 more
2012American Journal of Physiology. Heart and Circulatory Physiology107 citations Open access
Semantic Scholar
Gap Junctions
M. S. Nielsen, L. Axelsen, P. Sorgen, Vandana Verma +2 more
2012Comprehensive Physiology103 citations Open access
Semantic Scholar
Well-defined cross-linked antioxidant nanozymes for treatment of ischemic brain injury
D. Manickam, A. Brynskikh, Jennifer L. Kopanic, P. Sorgen +4 more
2012Journal of Controlled Release98 citations Open access
Semantic Scholar
Characterization of the pH-dependent Interaction between the Gap Junction Protein Connexin43 Carboxyl Terminus and Cytoplasmic Loop Domains*
Bethany J Hirst-Jensen, P. Sahoo, Fabien Kieken, M. Delmar +1 more
2007Journal of Biological Chemistry95 citations Open access
Semantic Scholar
Eps15 homology domain 1-associated tubules contain phosphatidylinositol-4-phosphate and phosphatidylinositol-(4,5)-bisphosphate and are required for efficient recycling.
M. Jović, Fabien Kieken, Naava Naslavsky, P. Sorgen +1 more
2009Molecular Biology of the Cell92 citations Open access
Semantic Scholar
Protein–Protein Interactions with Connexin 43: Regulation and Function
P. Sorgen, A. Trease, Gaelle Spagnol, M. Delmar +1 more
2018International Journal of Molecular Sciences91 citations Open access
Semantic Scholar
An approach to membrane protein structure without crystals
P. Sorgen, Yong-Lin Hu, L. Guan, H. Kaback +1 more
2002Proceedings of the National Academy of Sciences of the United States of America86 citations Open access
Semantic Scholar
Gap Junction Protein Cx37 Interacts With Endothelial Nitric Oxide Synthase in Endothelial Cells
Anna Pfenniger, Jean-Paul Derouette, Vandana Verma, Xianming Lin +9 more
2010Arteriosclerosis, Thrombosis and Vascular Biology83 citations Open access
Semantic Scholar
Connexin43 Forms Supramolecular Complexes through Non-Overlapping Binding Sites for Drebrin, Tubulin, and ZO-1
C. Ambrosi, Cynthia Ren, Gaelle Spagnol, G. Cavin +4 more
2016PLoS ONE69 citations Open access
Semantic Scholar
The Gap Junction Protein Connexin32 Interacts with the Src Homology 3/Hook Domain of Discs Large Homolog 1*
H. Duffy, I. Iacobas, Kylie Hotchkiss, Bethany J Hirst-Jensen +5 more
2007Journal of Biological Chemistry68 citations Open access
Semantic Scholar
Rabankyrin-5 interacts with EHD1 and Vps26 to regulate endocytic trafficking and retromer function
Jing Zhang, C. Reiling, James B. Reinecke, Iztok Prislan +4 more
2012Traffic : the International Journal of Intracellular Transport67 citations Open access
Semantic Scholar
EHD1 and Eps15 Interact with Phosphatidylinositols via Their Eps15 Homology Domains*
Naava Naslavsky, Juliati Rahajeng, S. Chenavas, P. Sorgen +1 more
2007Journal of Biological Chemistry64 citations Open access
Semantic Scholar
pH-dependent dimerization of the carboxyl terminal domain of Cx43.
P. Sorgen, H. Duffy, D. Spray, M. Delmar
2004Biophysical Journal64 citations Open access
Semantic Scholar
Differential Roles of C-terminal Eps15 Homology Domain Proteins as Vesiculators and Tubulators of Recycling Endosomes*
Bi-Shuang Cai, S. Giridharan, Jing Zhang, S. Saxena +6 more
2013Journal of Biological Chemistry59 citations Open access
Semantic Scholar
Effects of Phosphorylation on the Structure and Backbone Dynamics of the Intrinsically Disordered Connexin43 C-terminal Domain*
Rosslyn Grosely, Jennifer L. Kopanic, S. Nabors, Fabien Kieken +4 more
2013Journal of Biological Chemistry58 citations Open access
Semantic Scholar
Characterization of the Structure and Intermolecular Interactions between the Connexin40 and Connexin43 Carboxyl-terminal and Cytoplasmic Loop Domains*
D. Bouvier, Gaelle Spagnol, S. Chenavas, Fabien Kieken +5 more
2009Journal of Biological Chemistry53 citations Open access
Semantic Scholar
Membrane proximal ectodomain cleavage of MUC16 occurs in the acidifying Golgi/post-Golgi compartments
Srustidhar Das, P. Majhi, Mona H. Al-mugotir, S. Rachagani +2 more
2015Scientific Reports52 citations Open access
Semantic Scholar
Structural Studies of the Nedd4 WW Domains and Their Selectivity for the Connexin43 (Cx43) Carboxyl Terminus*
Gaelle Spagnol, Fabien Kieken, Jennifer L. Kopanic, Hanjun Li +4 more
2016Journal of Biological Chemistry50 citations Open access
Semantic Scholar
Mechanism for the Selective Interaction of C-terminal Eps15 Homology Domain Proteins with Specific Asn-Pro-Phe-containing Partners*
Fabien Kieken, Mahak Sharma, M. Jović, S. Giridharan +3 more
2010Journal of Biological Chemistry49 citations Open access
Semantic Scholar
Identification of a Novel Peptide That Interferes With the Chemical Regulation of Connexin43
Junko Shibayama, Rebecca Lewandowski, Fabien Kieken, W. Coombs +4 more
2006Circulation Research44 citations Open access
Semantic Scholar
Characterization of the Structure and Intermolecular Interactions between the Connexin 32 Carboxyl-terminal Domain and the Protein Partners Synapse-associated Protein 97 and Calmodulin*
K. Stauch, Fabien Kieken, P. Sorgen
2012Journal of Biological Chemistry43 citations Open access
Semantic Scholar
Connexin43 Carboxyl-Terminal Domain Directly Interacts with β-Catenin
Gaelle Spagnol, A. Trease, Li Zheng, M. Gutiérrez +5 more
2018International Journal of Molecular Sciences39 citations Open access
Semantic Scholar
Letter to the Editor: Sequence-specific resonance assignment of the carboxyl terminal domain of Connexin43
P. Sorgen, H. Duffy, S. Cahill, W. Coombs +3 more
2002Journal of Biomolecular NMR38 citations
Semantic Scholar
EH domain of EHD1
Fabien Kieken, M. Jović, Naava Naslavsky, S. Caplan +1 more
2007Journal of Biomolecular NMR36 citations
Semantic Scholar
Effect of charge substitutions at residue his-142 on voltage gating of connexin43 channels.
Junko Shibayama, Cristina Gutiérrez, Daniel González, Fabien Kieken +6 more
2006Biophysical Journal35 citations Open access
Semantic Scholar
In situ delivery of a curcumin-loaded dynamic hydrogel for the treatment of chronic peripheral neuropathy
Yunfan Kong, Wen Shi, Li Zheng, Dongze Zhang +7 more
2023Journal of Controlled Release34 citations Open access
Semantic Scholar
Structure of the Rhodobacter sphaeroides light-harvesting 1 beta subunit in detergent micelles.
P. Sorgen, S. Cahill, Ray D. Krueger-Koplin, S. Krueger-Koplin +2 more
2002Biochemistry34 citations
Semantic Scholar
Novel Pharmacophores of Connexin43 Based on the “RXP” Series of Cx43-binding Peptides
Vandana Verma, B. Larsen, W. Coombs, Xianming Lin +4 more
2009Circulation Research32 citations Open access
Semantic Scholar
TC-PTP directly interacts with connexin43 to regulate gap junction intercellular communication
Hanjun Li, Gaelle Spagnol, Naava Naslavsky, S. Caplan +1 more
2014Journal of Cell Science30 citations Open access
Semantic Scholar
Structural Changes in the Carboxyl Terminus of the Gap Junction Protein Connexin40 Caused by the Interaction with c-Src and Zonula Occludens-1
D. Bouvier, Fabien Kieken, Admir Kellezi, P. Sorgen
2008Cell Communication & Adhesion29 citations Open access
Semantic Scholar
Phosphorylation of Cx43 residue Y313 by Src contributes to blocking the interaction with Drebrin and disassembling gap junctions
Li Zheng, Hanjun Li, A. Cannon, A. Trease +6 more
2018Journal of Molecular and Cellular Cardiology28 citations Open access
Semantic Scholar
Carboxy terminus and pore-forming domain properties specific to Cx37 are necessary for Cx37-mediated suppression of insulinoma cell proliferation.
Tasha K. Nelson, P. Sorgen, J. Burt
2013American Journal of Physiology - Cell Physiology27 citations Open access
Semantic Scholar
Amphiphilic polyanhydride-based recombinant MUC4β-nanovaccine activates dendritic cells
Kasturi Banerjee, S. Gautam, Prakash G. Kshirsagar, K. Ross +8 more
2019Genes & cancer26 citations Open access
Semantic Scholar
EHD3 Protein Is Required for Tubular Recycling Endosome Stabilization, and an Asparagine-Glutamic Acid Residue Pair within Its Eps15 Homology (EH) Domain Dictates Its Selective Binding to NPF Peptides*
Kriti Bahl, Shuwei Xie, Gaelle Spagnol, P. Sorgen +2 more
2016Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Mechanism for modulation of gating of connexin26-containing channels by taurine
Darren Locke, Fabien Kieken, L. Tao, P. Sorgen +1 more
2011The Journal of General Physiology25 citations Open access
Semantic Scholar
Regulation of Cx37 channel and growth-suppressive properties by phosphorylation
Nicole L. Jacobsen, Tasha K. Pontifex, Hanjun Li, J. Solan +3 more
2017Journal of Cell Science24 citations Open access
Semantic Scholar
Regulation of Connexin43 Function and Expression by Tyrosine Kinase 2*
Hanjun Li, Gaelle Spagnol, Li Zheng, K. Stauch +1 more
2016Journal of Biological Chemistry23 citations Open access
Semantic Scholar
Inhibition of Pyk2 and Src activity improves Cx43 gap junction intercellular communication
Li Zheng, A. Trease, Kenichi Katsurada, Gaelle Spagnol +5 more
2020Journal of Molecular and Cellular Cardiology19 citations Open access
Semantic Scholar
Characterization of the connexin45 carboxyl-terminal domain structure and interactions with molecular partners.
Jennifer L. Kopanic, Mona H. Al-mugotir, Fabien Kieken, Sydney J. Zach +2 more
2014Biophysical Journal19 citations Open access
Semantic Scholar
Degradation of gap junction connexins is regulated by the interaction with Cx43-interacting protein of 75 kDa (CIP75)
Jennifer L. Kopanic, B. Schlingmann, Michael Koval, Alan F. Lau +2 more
2015Biochemical Journal16 citations Open access
Semantic Scholar
Molecular Organization and Regulation of the Cardiac Gap Junction Channel Connexin43
M. Delmar, H. Duffy, P. Sorgen, S. Taffet +1 more
200416 citations
Semantic Scholar
Structural order in Pannexin 1 cytoplasmic domains
Gaelle Spagnol, P. Sorgen, D. Spray
2014Channels15 citations Open access
Semantic Scholar
A History of Gap Junction Structure: Hexagonal Arrays to Atomic Resolution
Rosslyn Grosely, P. Sorgen
2013Cell Communication & Adhesion14 citations Open access
Semantic Scholar

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Gaelle Spagnol×16
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Gaelle Spagnol — researcher profile on SciRah
Fabien Kieken×14
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Fabien Kieken — researcher profile on SciRah
M. Delmar×13
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M. Delmar — researcher profile on SciRah
H. Duffy×9
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H. Duffy — researcher profile on SciRah

Naava Naslavsky

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S. Caplan — researcher profile on SciRah

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W. Coombs — researcher profile on SciRah

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D. Spray — researcher profile on SciRah

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S. Taffet — researcher profile on SciRah

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Hanjun Li — researcher profile on SciRah

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M. Girvin — researcher profile on SciRah

Jennifer L. Kopanic×5

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Jennifer L. Kopanic — researcher profile on SciRah