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Yan-Qing Kan · SciRah

Researcher profile · Semantic Scholar

Yan-Qing Kan

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Yan-Qing Kan — researcher profile on SciRah

h-index: 17
Works: 24
Citations: 943

Most-cited papers

Vasoactive Intestinal Peptide and Pituitary Adenylate Cyclase-activating Polypeptide Inhibit Tumor Necrosis Factor α Transcriptional Activation by Regulating Nuclear Factor-kB and cAMP Response Element-binding Protein/c-Jun*
M. Delgado, E. Muñoz-Elías, Yan-Qing Kan, I. Gozes +4 more
1998Journal of Biological Chemistry192 citations Open access
Semantic Scholar
Vasoactive Intestinal Peptide and Pituitary Adenylyl Cyclase-Activating Polypeptide Inhibit Tumor Necrosis Factor-α Production in Injured Spinal Cord and in Activated Microglia via a cAMP-Dependent Pathway
Woong-Ki Kim, Yan-Qing Kan, D. Ganea, Ronald P. Hart +2 more
2000Journal of Neuroscience139 citations Open access
Semantic Scholar
Regulation of energy homeostasis by bombesin receptor subtype-3: selective receptor agonists for the treatment of obesity.
Xiao-Ming Guan, Howard Y. Chen, Peter H. Dobbelaar, Yan Dong +27 more
2010Cell Metabolism84 citations Open access
Semantic Scholar
Antiobesity Effect of MK-5046, a Novel Bombesin Receptor Subtype-3 Agonist
Xiao-Ming Guan, Joseph M. Metzger, Liming Yang, Kate A Raustad +18 more
2011Journal of Pharmacology and Experimental Therapeutics54 citations
Semantic Scholar
Discovery of MK-7725, A Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity.
H. Chobanian, Yan Guo, Ping Liu, M. Chioda +20 more
2011ACS Medicinal Chemistry Letters52 citations Open access
Semantic Scholar
Molecular Profiling Reveals a Common Metabolic Signature of Tissue Fibrosis
Ji Zhang, E. Muise, Seongah Han, Peter S. Kutchukian +29 more
2020Cell Reports Medicine51 citations Open access
Semantic Scholar
An integrin antagonist (MK‐0429) decreases proteinuria and renal fibrosis in the ZSF1 rat diabetic nephropathy model
Xiao-Yan Zhou, Ji Zhang, R. Haimbach, Wei Zhu +12 more
2017Pharmacology Research & Perspectives49 citations Open access
Semantic Scholar
Discovery of MK-5046, a Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity.
I. Sebhat, Christopher L. Franklin, M. M. Lo, David Chen +18 more
2011ACS Medicinal Chemistry Letters47 citations Open access
Semantic Scholar
Discovery of benzodiazepine sulfonamide-based bombesin receptor subtype 3 agonists and their unusual chirality.
Ping Liu, T. Lanza, M. Chioda, Carrie P. Jones +28 more
2011ACS Medicinal Chemistry Letters42 citations Open access
Semantic Scholar
The design and synthesis of potent, selective benzodiazepine sulfonamide bombesin receptor subtype 3 (BRS-3) agonists with an increased barrier of atropisomerization.
H. Chobanian, Yan Guo, Ping Liu, T. Lanza +25 more
2012Bioorganic & Medicinal Chemistry39 citations Open access
Semantic Scholar
Discovery of substituted biphenyl imidazoles as potent, bioavailable bombesin receptor subtype-3 agonists.
Shu-Wen He, Peter H. Dobbelaar, Jian Liu, Tian-Ying Jian +29 more
2010Bioorganic & Medicinal Chemistry Letters26 citations Open access
Semantic Scholar
Synthesis and SAR of heterocyclic carboxylic acid isosteres based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity.
Mark Hadden, Allan J. Goodman, Cheng Guo, P. Guzzo +19 more
2010Bioorganic & Medicinal Chemistry Letters24 citations Open access
Semantic Scholar
PAN-AMPK Activation Improves Renal Function in a Rat Model of Progressive Diabetic Nephropathy
Xiao-Yan Zhou, E. Muise, R. Haimbach, I. Sebhat +7 more
2019Journal of Pharmacology and Experimental Therapeutics23 citations Open access
Semantic Scholar
Dose-dependent effects of siRNA-mediated inhibition of SCAP on PCSK9, LDLR, and plasma lipids in mouse and rhesus monkey
Kristian K. Jensen, Marija Tadin-Strapps, Sheng-Ping Wang, J. Hubert +18 more
2016Journal of Lipid Research22 citations Open access
Semantic Scholar
Safety and immunogenicity of V114, a 15-valent pneumococcal conjugate vaccine, in adults living with HIV
L. Mohapi, Y. Pinedo, O. Osiyemi, K. Supparatpinyo +13 more
2021AIDS (London)19 citations Open access
Semantic Scholar
Diacylglycerol Acyltransferase-1 (DGAT1) Inhibition Perturbs Postprandial Gut Hormone Release
Hua V. Lin, Dunlu Chen, Zhu Shen, Lei Zhu +13 more
2013PLoS ONE19 citations Open access
Semantic Scholar
Synthesis of 7-benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-ylamine and its analogs as bombesin receptor subtype-3 agonists.
Cheng Guo, P. Guzzo, Mark Hadden, B. J. Sargent +12 more
2010Bioorganic & Medicinal Chemistry Letters19 citations Open access
Semantic Scholar
Synthesis and SAR of derivatives based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity.
Jian Liu, Shu-Wen He, Tian-Ying Jian, Peter H. Dobbelaar +25 more
2010Bioorganic & Medicinal Chemistry Letters15 citations Open access
Semantic Scholar
Pyridinesulfonylureas and pyridinesulfonamides as selective bombesin receptor subtype-3 (BRS-3) agonists.
M. M. Lo, H. Chobanian, O. Palyha, Yan-Qing Kan +7 more
2011Bioorganic & Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
Potential mechanism of enhanced postprandial glucagon‐like peptide‐1 release following treatment with a diacylglycerol acyltransferase 1 inhibitor
Jin-Qi Liu, David G. McLaren, Dunlu Chen, Yan-Qing Kan +9 more
2015Pharmacology Research & Perspectives11 citations Open access
Semantic Scholar
High-Throughput Screening to Identify Small Molecules That Selectively Inhibit APOL1 Protein Level in Podocytes
J. Choy, Yan-Qing Kan, S. Cifelli, Josephine Johnson +21 more
2021SLAS discovery : advancing life sciences R & D4 citations Open access
Semantic Scholar
PAN-AMPK ACTIVATION IMPROVES RENAL FUNCTION IN A RAT MODEL OF PROGRESSIVE DIABETIC NEPHROPATHY
Xiao-Yan Zhou, E. Muise, R. Haimbach, I. Sebhat +7 more
20191 citations
Semantic Scholar
1 TITLE
Xiao-Yan Zhou, E. Muise, R. Haimbach, I. Sebhat +7 more
20190 citations
Semantic Scholar
Abstract 18950: PCSK9 and LDL-C Lowering Effect of SCAP Targeting siRNA in Mouse and Non-Human Primate Models
Kristian K. Jensen, Marija Tadin-Strapps, Sheng-Ping Wang, K. Herath +12 more
20140 citations
Semantic Scholar

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