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Peter H. Dobbelaar · SciRah

Researcher profile · Semantic Scholar

Peter H. Dobbelaar

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Peter H. Dobbelaar — researcher profile on SciRah

h-index: 11
Works: 19
Citations: 299

Most-cited papers

Regulation of energy homeostasis by bombesin receptor subtype-3: selective receptor agonists for the treatment of obesity.
Xiao-Ming Guan, Howard Y. Chen, Peter H. Dobbelaar, Yan Dong +27 more
2010Cell Metabolism84 citations Open access
Semantic Scholar
Discovery of substituted biphenyl imidazoles as potent, bioavailable bombesin receptor subtype-3 agonists.
Shu-Wen He, Peter H. Dobbelaar, Jian Liu, Tian-Ying Jian +29 more
2010Bioorganic & Medicinal Chemistry Letters26 citations Open access
Semantic Scholar
Discovery of highly potent and efficacious MC4R agonists with spiroindane N-Me-1,2,4-triazole privileged structures for the treatment of obesity.
Shu-Wen He, Zhi-Xiong Ye, Peter H. Dobbelaar, R. Bakshi +23 more
2010Bioorganic & Medicinal Chemistry Letters23 citations Open access
Semantic Scholar
Discovery of a spiroindane based compound as a potent, selective, orally bioavailable melanocortin subtype-4 receptor agonist.
Shu-Wen He, Zhi-Xiong Ye, Peter H. Dobbelaar, I. Sebhat +26 more
2010Bioorganic & Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
Discovery of MK-1421, a Potent, Selective sstr3 Antagonist, as a Development Candidate for Type 2 Diabetes
Shrenik K. Shah, Shu-Wen He, Liangqin Guo, Quang T. Truong +40 more
2015ACS Medicinal Chemistry Letters17 citations Open access
Semantic Scholar
The Discovery of MK-4256, a Potent SSTR3 Antagonist as a Potential Treatment of Type 2 Diabetes.
Shu-Wen He, Zhi-Xiong Ye, Quang T. Truong, Shrenik K. Shah +38 more
2012ACS Medicinal Chemistry Letters17 citations Open access
Semantic Scholar
Spiroindane based amides as potent and selective MC4R agonists for the treatment of obesity.
Shu-Wen He, Zhi-Xiong Ye, Peter H. Dobbelaar, I. Sebhat +21 more
2010Bioorganic & Medicinal Chemistry Letters16 citations Open access
Semantic Scholar
Facile one-pot method for the synthesis of novel glycosylidene-based quinolines
Peter H. Dobbelaar, C. Marzabadi
201016 citations
Semantic Scholar
Synthesis and SAR of derivatives based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity.
Jian Liu, Shu-Wen He, Tian-Ying Jian, Peter H. Dobbelaar +25 more
2010Bioorganic & Medicinal Chemistry Letters15 citations Open access
Semantic Scholar
Stimulation of Glucose-Dependent Insulin Secretion by a Potent, Selective sst3 Antagonist.
A. Pasternak, Zhe Feng, R. D. de Jesus, Zhi-Xiong Ye +17 more
2012ACS Medicinal Chemistry Letters14 citations Open access
Semantic Scholar
Discovery of potent, selective, and orally bioavailable 3H-spiro[isobenzofuran-1,4'-piperidine] based melanocortin subtype-4 receptor agonists.
Liangqin Guo, Zhi-Xiong Ye, Jian Liu, Shu-Wen He +21 more
2010Bioorganic & Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
Povarov reactions of exo-glycals: preparation of C-linked, quinoline analogues
Peter H. Dobbelaar, C. Marzabadi
201111 citations
Semantic Scholar
Investigation of Cardiovascular Effects of Tetrahydro-β-carboline sstr3 antagonists.
Shu-Wen He, Zhong Lai, Zhi-Xiong Ye, Peter H. Dobbelaar +35 more
2014ACS Medicinal Chemistry Letters10 citations Open access
Semantic Scholar
SAR exploration at the C-3 position of tetrahydro-β-carboline sstr3 antagonists.
Shu-Wen He, Peter H. Dobbelaar, Liangqin Guo, Zhi-Xiong Ye +38 more
2016Bioorganic & Medicinal Chemistry Letters7 citations Open access
Semantic Scholar
Optimization of privileged structures for selective and potent melanocortin subtype-4 receptor ligands.
Q. Hong, R. Bakshi, James P. Dellureficio, Shu-Wen He +27 more
2010Bioorganic & Medicinal Chemistry Letters7 citations Open access
Semantic Scholar
Catalytic asymmetric hydrogenation to access spiroindane dimethyl acetic acid
Shu-Wen He, C. Shultz, Zhong Lai, R. Eid +3 more
20115 citations
Semantic Scholar
Synthesis of Novel Glycosylidene-Based Quinolines
Peter H. Dobbelaar
20101 citations
Semantic Scholar
Povarov Reactions of exo‐Glycals: Preparation of C‐Linked, Quinoline Analogues.
Peter H. Dobbelaar, C. Marzabadi
20120 citations
Semantic Scholar
CCDC 760573: Experimental Crystal Structure Determination
Shu-Wen He, Zhi-Xiong Ye, Peter H. Dobbelaar, I. Sebhat +26 more
20100 citations
Semantic Scholar

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