Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Xiao-Ming Guan · SciRah

Researcher profile · Semantic Scholar

Xiao-Ming Guan

Share profile

Xiao-Ming Guan — researcher profile on SciRah

h-index: 33
Works: 54
Citations: 8,782

Most-cited papers

Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues.
Xiao-Ming Guan, Hong Yu, O. Palyha, K. McKee +5 more
1997Brain Research. Molecular Brain Research1,181 citations
Semantic Scholar
Distribution of orexin receptor mRNA in the rat brain
Prashant G. Trivedi, Hong Yu, D. Macneil, L. van der Ploeg +1 more
1998FEBS Letters1,001 citations Open access
Semantic Scholar
Inactivation of the mouse melanocortin-3 receptor results in increased fat mass and reduced lean body mass
Airu S Chen, D. J. Marsh, M. Trumbauer, E. Frazier +17 more
2000Nature Genetics923 citations
Semantic Scholar
Orexigenic action of peripheral ghrelin is mediated by neuropeptide Y and agouti-related protein.
Howard Y. Chen, M. Trumbauer, Airu S Chen, Drew T. Weingarth +13 more
2004Endocrinology685 citations Open access
Semantic Scholar
Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism
D. J. Marsh, Drew T. Weingarth, Dawn E Novi, Howard Y. Chen +18 more
2002Proceedings of the National Academy of Sciences of the United States of America569 citations Open access
Semantic Scholar
Neither Agouti-Related Protein nor Neuropeptide Y Is Critically Required for the Regulation of Energy Homeostasis in Mice
S. Qian, Howard Y. Chen, Drew T. Weingarth, M. Trumbauer +13 more
2002Molecular and Cellular Biology446 citations Open access
Semantic Scholar
Identification of receptors for neuromedin U and its role in feeding
A. Howard, Rui-Ping Wang, S. Pong, T. Mellin +21 more
2000Nature405 citations
Semantic Scholar
A role for the melanocortin 4 receptor in sexual function
L. van der Ploeg, W. J. Martin, A. Howard, R. Nargund +30 more
2002Proceedings of the National Academy of Sciences of the United States of America299 citations Open access
Semantic Scholar
Identification and Characterization of Novel Mammalian Neuropeptide FF-like Peptides That Attenuate Morphine-induced Antinociception*
Qing-Yun Liu, Xiao-Ming Guan, W. J. Martin, T. McDonald +13 more
2001Journal of Biological Chemistry269 citations Open access
Semantic Scholar
Enhancement of membrane insertion and function in a type IIIb membrane protein following introduction of a cleavable signal peptide.
Xiao-Ming Guan, T. S. Kobilka, B. Kobilka
1992Journal of Biological Chemistry258 citations Open access
Semantic Scholar
Melanin-concentrating hormone receptor subtypes 1 and 2: species-specific gene expression.
Carina P. Tan, H. Sano, H. Iwaasa, Jie Pan +17 more
2002Genomics255 citations
Semantic Scholar
Role of the melanocortin-4 receptor in metabolic rate and food intake in mice
Airu S Chen, Joseph M. Metzger, M. Trumbauer, Xiao-Ming Guan +12 more
2000Transgenic research243 citations
Semantic Scholar
Serotonin microinfusion into the ventral tegmental area increases accumbens dopamine release.
Xiao-Ming Guan, W. Mcbride
1989Brain Research Bulletin198 citations
Semantic Scholar
Small molecule insulin mimetics reduce food intake and body weight and prevent development of obesity
E. Air, M. Strowski, S. Benoit, Stacey L. Conarello +5 more
2002Nature Medicine185 citations
Semantic Scholar
Mutant Human Presenilin 1 Protects presenilin 1 Null Mouse against Embryonic Lethality and Elevates Aβ1–42/43 Expression
S. Qian, Ping Jiang, Xiao-Ming Guan, Gurparkash Singh +5 more
1998175 citations Open access
Semantic Scholar
Differential expression of mRNA for leptin receptor isoforms in the rat brain.
Xiao-Ming Guan, J. Hess, Hong Yu, Patricia J. Hey +1 more
1997Molecular and Cellular Endocrinology171 citations
Semantic Scholar
The role of melanocortins in body weight regulation: opportunities for the treatment of obesity.
D. Macneil, A. Howard, Xiao-Ming Guan, T. Fong +14 more
2002European Journal of Pharmacology150 citations Open access
Semantic Scholar
Induction of neuropeptide Y expression in dorsomedial hypothalamus of diet‐induced obese mice
Xiao-Ming Guan, Hong Yu, M. Trumbauer, E. Frazier +2 more
1998NeuroReport147 citations
Semantic Scholar
Identification of a single amino acid residue responsible for the binding of a class of beta-adrenergic receptor antagonists to 5-hydroxytryptamine1A receptors.
Xiao-Ming Guan, S. Peroutka, B. Kobilka
1992Molecular Pharmacology129 citations
Semantic Scholar
Antiobesity Efficacy of a Novel Cannabinoid-1 Receptor Inverse Agonist, N-[(1S,2S)-3-(4-Chlorophenyl)-2-(3-cyanophenyl)-1-methylpropyl]-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]oxy}propanamide (MK-0364), in Rodents
T. Fong, Xiao-Ming Guan, D. J. Marsh, Chun-Pyn Shen +22 more
2007Journal of Pharmacology and Experimental Therapeutics103 citations
Semantic Scholar
Regulation of energy homeostasis by bombesin receptor subtype-3: selective receptor agonists for the treatment of obesity.
Xiao-Ming Guan, Howard Y. Chen, Peter H. Dobbelaar, Yan Dong +27 more
2010Cell Metabolism84 citations Open access
Semantic Scholar
A neuropeptide Y Y5 antagonist selectively ameliorates body weight gain and associated parameters in diet-induced obese mice.
A. Ishihara, A. Kanatani, S. Mashiko, Takeshi Tanaka +20 more
2006Proceedings of the National Academy of Sciences of the United States of America77 citations
Semantic Scholar
Molecular basis of the pharmacological difference between rat and human bombesin receptor subtype-3 (BRS-3).
Jie Liu, Z. Lao, Jiaping Zhang, M. Schaeffer +4 more
2002Biochemistry69 citations
Semantic Scholar
Distribution of neuromedin U receptor subtype 2 mRNA in the rat brain.
Xiao-Ming Guan, Hong Yu, Q. Jiang, L. van der Ploeg +1 more
2001Brain research. Gene expression patterns61 citations
Semantic Scholar
Bombesin receptor subtype-3 (BRS-3) regulates glucose-stimulated insulin secretion in pancreatic islets across multiple species.
Yue Feng, Xiao-Ming Guan, Jing Li, Joseph M. Metzger +6 more
2011Endocrinology60 citations
Semantic Scholar
Regional serotonin1A receptors in the CNS of alcohol-preferring and -nonpreferring rats.
W. Mcbride, Xiao-Ming Guan, E. Chernet, L. Lumeng +1 more
1994Pharmacology, Biochemistry and Behavior59 citations
Semantic Scholar
Exploring the site of anorectic action of peripherally administered synthetic melanocortin peptide MT-II in rats.
Prashant G. Trivedi, Michael M Jiang, Constantin Tamvakopoulos, Xiao-Lan Shen +5 more
2003Brain Research55 citations
Semantic Scholar
Antiobesity Effect of MK-5046, a Novel Bombesin Receptor Subtype-3 Agonist
Xiao-Ming Guan, Joseph M. Metzger, Liming Yang, Kate A Raustad +18 more
2011Journal of Pharmacology and Experimental Therapeutics54 citations
Semantic Scholar
Discovery of MK-7725, A Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity.
H. Chobanian, Yan Guo, Ping Liu, M. Chioda +20 more
2011ACS Medicinal Chemistry Letters52 citations Open access
Semantic Scholar
Discovery of MK-5046, a Potent, Selective Bombesin Receptor Subtype-3 Agonist for the Treatment of Obesity.
I. Sebhat, Christopher L. Franklin, M. M. Lo, David Chen +18 more
2011ACS Medicinal Chemistry Letters47 citations Open access
Semantic Scholar
Discovery of benzodiazepine sulfonamide-based bombesin receptor subtype 3 agonists and their unusual chirality.
Ping Liu, T. Lanza, M. Chioda, Carrie P. Jones +28 more
2011ACS Medicinal Chemistry Letters42 citations Open access
Semantic Scholar
The design and synthesis of potent, selective benzodiazepine sulfonamide bombesin receptor subtype 3 (BRS-3) agonists with an increased barrier of atropisomerization.
H. Chobanian, Yan Guo, Ping Liu, T. Lanza +25 more
2012Bioorganic & Medicinal Chemistry39 citations Open access
Semantic Scholar
Differential regulation of neuropeptide Y receptors in the brains of NPY knock-out mice.
Prashant G. Trivedi, Hong Yu, M. Trumbauer, Howard Y. Chen +2 more
2001Peptides37 citations
Semantic Scholar
Body temperature as a mouse pharmacodynamic response to bombesin receptor subtype-3 agonists and other potential obesity treatments.
Joseph M. Metzger, K. Gagen, Kate A Raustad, Liming Yang +10 more
2010American Journal of Physiology. Endocrinology and Metabolism33 citations
Semantic Scholar
Discovery of substituted biphenyl imidazoles as potent, bioavailable bombesin receptor subtype-3 agonists.
Shu-Wen He, Peter H. Dobbelaar, Jian Liu, Tian-Ying Jian +29 more
2010Bioorganic & Medicinal Chemistry Letters26 citations Open access
Semantic Scholar
Synthesis and SAR of heterocyclic carboxylic acid isosteres based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity.
Mark Hadden, Allan J. Goodman, Cheng Guo, P. Guzzo +19 more
2010Bioorganic & Medicinal Chemistry Letters24 citations Open access
Semantic Scholar
Small-molecule insulin mimetic reduces hyperglycemia and obesity in a nongenetic mouse model of type 2 diabetes.
M. Strowski, Zhihua Li, D. Szalkowski, Xiao-Lan Shen +4 more
2004Endocrinology23 citations Open access
Semantic Scholar
Basic mechanisms of action of drugs used in the treatment of essential tremor.
Xiao-Ming Guan, S. Peroutka
1990Clinical neuropharmacology22 citations
Semantic Scholar
Synthesis of 7-benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-ylamine and its analogs as bombesin receptor subtype-3 agonists.
Cheng Guo, P. Guzzo, Mark Hadden, B. J. Sargent +12 more
2010Bioorganic & Medicinal Chemistry Letters19 citations Open access
Semantic Scholar
Mutant human presenilin 1 protects presenilin 1 null mouse against embryonic lethality and elevates Abeta1-42/43 expression.
S. Qian, P. Jiang, Xiao-Ming Guan, G. Singh +5 more
1998Neuron18 citations
Semantic Scholar
Synthesis and SAR of derivatives based on 2-biarylethylimidazole as bombesin receptor subtype-3 (BRS-3) agonists for the treatment of obesity.
Jian Liu, Shu-Wen He, Tian-Ying Jian, Peter H. Dobbelaar +25 more
2010Bioorganic & Medicinal Chemistry Letters15 citations Open access
Semantic Scholar
Pyridinesulfonylureas and pyridinesulfonamides as selective bombesin receptor subtype-3 (BRS-3) agonists.
M. M. Lo, H. Chobanian, O. Palyha, Yan-Qing Kan +7 more
2011Bioorganic & Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
Characterization of a novel and selective cannabinoid CB1 receptor inverse agonist, Imidazole 24b, in rodents.
L. Shearman, D. Stribling, R. Camacho, K. Rosko +20 more
2008European Journal of Pharmacology12 citations
Semantic Scholar
Increased melanin concentrating hormone receptor type I in the human hypothalamic infundibular nucleus in cachexia.
U. Unmehopa, J. V. van Heerikhuize, Wenda Spijkstra, J. Woods +9 more
2005Journal of Clinical Endocrinology and Metabolism12 citations Open access
Semantic Scholar
A neuropeptide Y Y 5 antagonist selectively ameliorates body weight gain and associated parameters in diet-induced obese mice
A. Ishihara, A. Kanatani, S. Mashiko, Takeshi Tanaka +20 more
200611 citations
Semantic Scholar
Erratum to: Distribution of orexin receptor mRNA in the rat brain (FEBS 21024)
Prashant G. Trivedi, Hong Yu, D. Macneil, L. van der Ploeg +1 more
199911 citations Open access
Semantic Scholar
Design and synthesis of (ant)-agonists that alter appetite and adiposity.
L. van der Ploeg, A. Kanatani, D. Macneil, T. Fong +3 more
2006Progress in Brain Research8 citations
Semantic Scholar
Cloning, Sequencing, and Expression of the Rhesus Monkey β2 Adrenergic Receptor
A. Amend, Xiao-Ming Guan
19955 citations
Semantic Scholar
5-benzyloxytryptamine: a relatively selective 5-hydroxytryptamine 1D/1B agent.
S. Peroutka, Bruce G. McCarthy, Xiao-Ming Guan
1991Life Science5 citations Open access
Semantic Scholar
Identification of differential genes in ovarian cancer using representational difference analysis of cDNA.
Hong Chen, Min Wang, Xin-Yan Wang, Shan Gao +2 more
2005Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih3 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

L. van der Ploeg×25
Invite
L. van der Ploeg — researcher profile on SciRah
Hong Yu×19
Invite
Hong Yu — researcher profile on SciRah
R. Nargund×16
Invite
R. Nargund — researcher profile on SciRah
O. Palyha×15
Invite
O. Palyha — researcher profile on SciRah

×15

Invite

D. J. Marsh — researcher profile on SciRah

Alison M. Strack×15

Invite

Alison M. Strack — researcher profile on SciRah

Joseph M. Metzger×14

Invite

Joseph M. Metzger — researcher profile on SciRah

Invite

L. Lin — researcher profile on SciRah

Invite

D. Macneil — researcher profile on SciRah

Invite

M. Reitman — researcher profile on SciRah

Howard Y. Chen×11

Invite

Howard Y. Chen — researcher profile on SciRah

Yan-Qing Kan×11

Invite

Yan-Qing Kan — researcher profile on SciRah